Clinical trials: Cognitive-behavioral Therapy
Generalized Anxiety Disorder
A Single-Component CBT for GAD
Generalized Anxiety Disorder (GAD) is a chronic condition that is characterized by excessive and uncontrollable worry and anxiety. In Canada, 3 to 4% of the population suffer from GAD at any point in time.
- Trial name
- NCT02552108
- Testing
- Behavioural experiments for intolerance of uncertainty (BE-IU)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universite du Quebec en Outaouais
Depression, Mental Disorder in Adolescence
The PATHway Study: Primary Care Based Depression Prevention in Adolescents
Prevention of depressive disorders has become a key priority for the NIMH, but the investigators have no widely available public health strategy to reduce morbidity and mortality.
- Trial name
- PATHway (NCT05203198)
- Testing
- Competent Adulthood Transition with Cognitive-Behavioral, Humanistic and Interpersonal Training
- Where
- 6 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Dementia, Cognitive Decline
Preventing Cognitive Decline: The CITA GO-ON Multi-domain Intervention Study
The GOIZ ZAINDU Gipuzkoa - GO - ON Study is an intervention trial to evaluate the efficacy of dementia prevention strategies in cognitively frail people.
- Conditions
- Dementia, Cognitive Decline, Prevention, Life Style
- Trial name
- CITA GO-ON (NCT04840030)
- Testing
- Multimodal intervention (MM-int)
- Where
- Spain
- Volunteers
- 1,094 people, healthy volunteers welcome
- Sponsor
- Fundacion CITA-alzheimer
Mental Health Issue
UNIPDES- An Internet-Based Transdiagnostic Intervention for College Students' Psychological Symptoms
This study is a randomised clinical trial. This study evaluates the effect of an internet-based intervention developed based on a transdiagnostic cognitive behavioural approach on psychological symptoms of university students.
- Trial name
- UNIPDES (NCT06245200)
- Testing
- UNIPDES - Internet Based Intervention - GUIDED, UNIPDES - Internet Based Intervention - UNGUIDED
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Anadolu University
Rumination, Depressive Symptoms
Can Rumination-Focused Cognitive Behavioral Therapy Reduce the Risk of Cardio-vascular Disease?
Many people know that a poor diet, exercise, smoking, and alcohol use cause heart disease. However, a less known factor that increases the risk of heart disease is depression.
- Conditions
- Rumination, Depressive Symptoms, Blood Pressure
- Trial name
- RFCBT-I (NCT05980130)
- Testing
- Rumination-Focused Cognitive Behavior Therapy
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Cognitive Behavior Group Therapy
Cognitive Behavioral Group Therapy for University Students
This study developed a culturally appropriate cognitive behavioral group prevention program for Mainland Chinese university students in Hong Kong.
- Trial name
- NCT04442854
- Testing
- cognitive behavioral group therapy
- Where
- Hong Kong
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Early Psychosis
PSYCHE Cognitive Remediation & Social Recovery Study
This study is a pilot feasibility study embedded in the Early Intervention in Psychosis (EIP) services in Ireland. It explores the feasibility and acceptability of a combined cognitive remediation training and social recovery…
- Trial name
- NCT06032182
- Testing
- CRESTR Intervention, CRESTR Control
- Where
- 5 sites in Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Cognitive Dysfunction
Adapting a Behavioral Intervention to Accommodate Cognitive Dysfunction in People Who Inject Drugs
The goal of this pilot work was to determine if the cognitive dysfunction accommodation strategies help patients retain/utilize more HIV prevention information and increase PrEP adherence.
- Trial name
- NCT05912374
- Testing
- standard Community-Friendly Health Recovery Program- Biobehavioral (CHRP-BB), enhanced Community-Friendly Health Recovery Program- Biobehavioral (CHRP-BB)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Depression
An Adaptive Intervention for Depression Among Latinos Living With HIV
This study will use a pilot sequential multiple assignment randomized trial (SMART) design to build an adaptive treatment strategy (ATS) for depression and engagement in HIV among Latinos living with HIV.
- Trial name
- Latino-SMART (NCT03668379)
- Testing
- Augment w/mHealth, Maintenance, Switch to CBT & mHealth
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Irritable Bowel Syndrome
Management of Irritable Bowel Syndrome in Primary Care (MIBS Trial)
Aims: 1. To pilot an randomized, controlled trial (RCT) to assess the effectiveness of the commonly prescribed medications in UK general practice for IBS: mebeverine (anti-spasmodic) and methylcellulose (bulking-agent) and of the…
- Trial name
- MIBS (NCT00934973)
- Testing
- mebeverine, methylcellulose, CBT website with support
- Where
- United Kingdom
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Hazel Everitt
Alcoholism
Individualized Assessment and Treatment for Alcoholism II
The object of this study is to develop a treatment for alcohol use disorders that is more effective than current CB treatments. Through a 2009 R-21 pilot project the investigators developed a cognitive-behavioral (CB) treatment…
- Trial name
- IATP2 (NCT03233802)
- Testing
- Individualized Assess & Treatment (IATP), Packaged Cognitive-Behavioral (PCBT), Case Management (CaseM)
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- UConn Health
Tobacco Dependence
Tobacco Dependence Treatment for Asian Americans
Nicotine dependence is very common among Asian Americans; yet, research on understanding and treating nicotine dependence in this group is almost nonexistent.
- Trial name
- NCT01091363
- Testing
- Standard, Deep Cultural
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Boston
Alzheimer Disease
The Dementia Study in Northern Norway
The Dementia Study in Northern Norway is an open controled intervention trial carried out in nine rural municipalities, five of which allocated to intervention and four to control.
- Trial name
- NCT00443014
- Testing
- Cognitive, physical and social stimulation
- Where
- Norway
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Insomnia
Improving Sleep With a Digital Cognitive Behavioral Therapy for Insomnia Application
Insomnia is an important public health problem and the most common sleep disorder in the general population. Up to 20% of adults in the United States suffer from insomnia disorder, and it has been associated with increased…
- Trial name
- STELLAR (NCT05991492)
- Testing
- Web-based Cognitive Behavioral Therapy for Insomnia (wCBT-I
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Depression
Optimizing Mindfulness Based Cognitive Therapy (MBCT) Maintenance
Mindfulness-Based Cognitive Therapy (MBCT) combines meditation practices from Mindfulness-Based Stress Reduction (MBSR) with cognitive behavioral therapy to improve mental health.
- Trial name
- OMM (NCT05859386)
- Testing
- Mindfulness maintenance program
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Knee Osteoarthritis
Occupational Therapy-Delivered Cognitive Behavioral Therapy for Symptomatic Knee Osteoarthritis
Knee osteoarthritis (OA) affects 27 million US adults and is a leading cause of pain and disability. Non-pharmacological interventions are recommended but are underutilized.
- Trial name
- ENGAGE (NCT02498847)
- Testing
- ENGAGE
- Where
- 2 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Health Services Accessibility, Rural Health
Health Ahead Comparative Effectiveness Study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening…
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services
- Trial name
- HACE (NCT07669168)
- Testing
- AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- William Brandenburg, MD
Depression, Anxiety, Alcohol Abuse
Cognitive-Behavioral Therapy for Young Adult Lesbian, Gay and Bisexual: Transdiagnostic Minority Stress Approach
Background: LGB people experience a large number of anxiety and mood disorders, and risk behaviors than heterosexual (Marshall et al., 2011).
- Conditions
- Depression, Anxiety, Alcohol Abuse, Sexual Compulsivity, Unsafe Sex
- Trial name
- NCT03980873
- Testing
- ESTEEM (Effective Sikills to Empower Effective Men)
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Depression / Major Depressive Disorder, Anxiety
Digital Single-Session Cognitive Behavioural Therapy in Healthy Adults
The goal of this study is to learn if digital single-session cognitive behavioural therapy can treat mental health in adults. The main question it aims to answer is: Does digital single-session cognitive behavioural therapy…
- Conditions
- Depression / Major Depressive Disorder, Anxiety, Anxiety Disorder Generalized
- Trial name
- CBT (NCT07873905)
- Testing
- Digital single-session cognitive behavioural therapy, Digital memory task
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Brunel University
Widespread Chronic Pain
The Maintaining Musculoskeletal Health Study
It is known from many studies that when patients have developed chronic widespread pain (CWP) or fibromyalgia that managing such symptoms is extremely challenging for both doctors and patients.
- Trial name
- MAmMOTH (NCT02668003)
- Testing
- Cognitive Behavioural Therapy
- Where
- 3 sites in United Kingdom
- Volunteers
- 1,002 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen