Clinical trials: Cohort
Osteoarthritis, Knee, Osteoarthritis, Hip
Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee
In this work the investigators will study the relationship between chronic musculoskeletal pain and abnormal blood flow (neovascularity) around the shoulder, hip and knee.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Osteo Arthritis Shoulders, Synovitis of Knee
- Trial name
- MRI (NCT05700682)
- Testing
- Shoulder/Hip/Knee Embolization with Embozene Microspheres
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Palo Alto Veterans Institute for Research
Brachytherapy, Squamous Cell Carcinomas
RISI in the Treatment of Recurrent Metastatic SCC of Thoracic Inlet Lymph Nodes
The malignant tumor at the thoracic entrance is difficult to be surgically removed, and radiotherapy or radiotherapy based comprehensive treatment is often chosen at the initial diagnosis.
- Trial name
- NCT04266327
- Testing
- 3D-printing Template-assisted CT-guided I-125 Seed Implantation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Allogenic Hematopoietic Cell Transplant, CAR-T Therapy
COVID-19 Vaccine in Patients After Allogeneic HCT, CAR-T Therapy and With Primary Immune Deficiency
The corona pandemic is a continuing global challenge due to Corona Virus 2019 (COVID-19). The purpose of the study is to confirm the accepted hypothesis from the recommendations of The European Society for Blood and Marrow…
- Conditions
- Allogenic Hematopoietic Cell Transplant, CAR-T Therapy, Primary Immunodeficiency
- Trial name
- NCT04724642
- Where
- Israel
- Volunteers
- 110 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Healthy
Study to Evaluate Safety, Tolerability, PK and PD of ALXN1007 in Healthy Subjects
The purpose of the study is to evaluate the safety, tolerability, PK and PD of a single-dose of ALXN1007 in healthy volunteers.
- Trial name
- NCT01454986
- Testing
- ALXN1007
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Alexion Pharmaceuticals, Inc.
Stroke
The Experiences of Family Caregivers of Stroke Patients: A Cross-sectional Study of a French Cohort
Stroke is the most common cause of non-traumatic disability in adults and ranks second among causes of dementia and third among causes of death.
- Trial name
- AVCAIDE (NCT04741451)
- Where
- 2 sites in France
- Volunteers
- 16 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Hepatic Impairment, Healthy Volunteers
Effect Of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of PF-06865571 In Subjects With Hepatic Impairment and in Healthy Subjects
The current study is proposed to evaluate whether there is any clinically meaningful effect of hepatic impairment on the plasma PK of PF-06865571.
- Trial name
- NCT04091061
- Testing
- PF-06865571 100 mg
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Cancer Survivors, Rehabilitation
Multidisciplinary Rehabilitation of Children and Adolescents After Acute Cancer Treatment
Recent numbers display a 85% survival-rate in children after a very harmful disease such as cancer. However, the survivors still experience mild to severe side effects of the primary disease or treatment.
- Conditions
- Cancer Survivors, Rehabilitation, Exercise Therapy
- Trial name
- NCT05154305
- Testing
- multidisciplinary intervention
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Hospital, Ghent
Alveolar Bone Loss
Effectiveness in Limiting the Need to Elevate the Maxillary Sinus
The aim of the present study is to evaluate the effectiveness of different alveolar preservation procedures performed at the time of extraction of the first or second upper molar in avoiding a maxillary sinus elevation or at…
- Trial name
- SO-GHI (NCT03357705)
- Testing
- alveolar ridge preservation with synthetic bone, alveolar ridge preservation with bovine collagen
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Covid19
Long-term Effects of COVID-19: a Comparative Cohort Study
This study is a longitudinal cohort study which investigates the effect of COVID-19 in ambulatory care. This study aims to assess the effect of COVID-19 beyond the acute phase, i.e.
- Trial name
- CoCo (NCT05002205)
- Testing
- Questionnaires, spirometry, ECG
- Volunteers
- 180 people
- Sponsor
- KU Leuven
Endometriosis
Guangdong Provincial Endometriosis Clinical Research Cohort
Endometriosis is a chronic condition that may cause pelvic pain, ovarian cysts, infertility, and recurrent symptoms. This prospective observational cohort study will enroll women aged 18 to 45 years with endometriosis and age…
- Trial name
- NCT07749053
- Where
- China
- Volunteers
- 716 people, healthy volunteers welcome
- Sponsor
- Li Li
Parotid Neoplasm, Bupivacaine
Clinical Tolerance of an Intraparotid Injection of Bupivacaine, Combined With Dexamethasone, After Parotidectomy for Benign Tumor
There has been a paradigm shift toward less invasive surgical techniques for parotidectomies, primarily to mitigate post-surgical complications.
- Conditions
- Parotid Neoplasm, Bupivacaine, Dexamethasone
- Trial name
- PAROCAINE (NCT07812259)
- Testing
- Intraparotid injection of bupivacaine/ dexamethasone
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
NUT Carcinoma
Multicenter Retrospective Cohort of Pulmonary NUT Carcinoma
This study is a multi-center, retrospective observational study of patients with lung NUT carcinoma. Existing clinical records from participating hospitals will be reviewed to describe patient characteristics, treatments, and…
- Trial name
- NCT07459127
- Testing
- Standard-of-care anticancer treatment (retrospective)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Three Gorges Hospital of Chongqing University
Postoperative Pain
Postoperative Pain Management of Therapeutic Surgery: a Prospective, Observational Cohort Study.
Poor management of post-operative acute pain can contribute to medical complications including pneumonia, deep vein thrombosis, infection and delayed healing, as well as the development of chronic.
- Trial name
- NCT04578483
- Testing
- ERDS group
- Where
- Taiwan
- Volunteers
- 634 people
- Sponsor
- China Medical University Hospital
Cardiovascular Diseases, Coronary Disease
Neighborhoods and CVD Risk in a Multiethnic Cohort - Ancillary to MESA
To investigate if neighborhood characteristics are related to disease risk in a multiethnic cohort.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Atherosclerosis
- Trial name
- NCT00063557
- Sponsor
- University of Michigan
COVID-19 Infection
Immunosupressive Treatment in COVID-19 Patients
SAM-COVID is a retrospective cohort study that aims to determine the impact of immunosuppressive drugs and immunoglubulins in the outcome of patients with COVID-19.
- Trial name
- SAM-COVID (NCT04382781)
- Testing
- NO-Immunosuppressive, Immunosuppressive, Immunoglubulins
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Spanish Network for Research in Infectious Diseases
Unresectable Stage III, Stage IV Melanoma
An Open-Label, 2-Cohort, Multicenter, Study of Lenvatinib in Previously Treated Subjects With Unresectable Stage III or Stage IV Melanoma
The purpose of this study is to assess the objective response rate of lenvatinib in previously treated participants with American Joint Committee on Cancer (AJCC) unresectable Stage III or Stage IV melanoma and disease…
- Trial name
- NCT01136967
- Testing
- Lenvatinib
- Where
- 95 sites in United States, Australia and 2 more
- Volunteers
- 182 people
- Sponsor
- Eisai Inc.
Arrhythmogenic Cardiomyopathy
Risk Stratification, Early Prevention and Treatment Strategies for Arrhythmogenic Cardiomyopathy
This study will include patients diagnosed with Arrhythmogenic cardiomyopathy (ACM) in the First Affiliated Hospital of Xi 'an Jiaotong University and other centers, and collect clinical data and biological samples of patients…
- Trial name
- STARTER (NCT06352307)
- Testing
- Diagnosis of ACM
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Heart Failure
Evalutation of a Hybrid Care Pathway With Remote MONitoring for Heart Failure
Heart failure is a long-term condition in which the heart cannot pump blood as well as it should. People with heart failure often need to be admitted to hospital when their symptoms suddenly get worse, which affects their quality…
- Trial name
- HARMONY-HF (NCT07680634)
- Testing
- Hybrid heart failure care pathway
- Where
- 7 sites in Netherlands
- Volunteers
- 6,000 people
- Sponsor
- St. Antonius Hospital
Idiopathic Pulmonary Fibrosis (IPF)
Idiopathic Pulmonary Fibrosis Cohort of TCM
This study, based on past registration records, evaluates the clinical efficacy of traditional Chinese medicine in treating IPF in the real world, identifies advantageous populations and clinical targets, and provides references…
- Trial name
- NCT07162870
- Testing
- Traditional Chinese medicine (TCM), Non-traditional Chinese medicine (non-TCM)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Body Weight, Obesity
Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes
The Nordic Diet is a dietary pattern rich in traditional Nordic foods, including berries, grains, and fatty fish common in northern Europe.
- Conditions
- Body Weight, Obesity, Overweight and Obesity, Obesity, Abdominal
- Trial name
- NCT04094194
- Testing
- Nordic diet
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
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