Clinical trials: Cohort
Anxiety Disorders, Post Traumatic Stress Disorder
Psychological Impact of Admission With Covid-19 During the SARS-CoV-2 Pandemic: Naturalistic Cohort Study With a Digital Intervention
Studies have shown that admission to hospital during a coronavirus epidemic is associated with increased levels of anxiety, depression and panic disorder.
- Conditions
- Anxiety Disorders, Post Traumatic Stress Disorder, Depressive Disorder, Covid19
- Trial name
- FeelGood (NCT04449627)
- Testing
- Feeling Good Digital App
- Volunteers
- 125 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Bimaxillary Protrusion
Evaluation of Smile Esthetics in Orthodontically Treated Patients With Bimaxillary-dentoalveolar Protrusion
Evaluation of Smile Esthetics in Orthodontically Treated Adult Female Patients with Bimaxillary-dentoalveolar Protrusion. A Retrospective Cohort Study.
- Trial name
- NCT03074370
- Where
- Egypt
- Volunteers
- 19 people
- Sponsor
- Cairo University
Placenta Accreta Spectrum
Risk Factors, Prognosis and Prediction Models for Placenta Accreta Without Prior Cesarean Section
1. Identify the risk factors for Placenta accreta spectrum (PAS) disorders in women without prior caesarean section (CS). 2. Clarify the prognostic factors of the disease and explore individualized treatment options to improve…
- Trial name
- NCT06383923
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Sickle Cell Disease
Cohort Study of Sickle Cell Patients Evaluating Analgesic Strategies and Their Consequences
To date, there is no comprehensive data among adults with sickle cell disease concerning the prevalence of consumption of level 2 and 3 analgesics at home and the use of cannabis or CBD for analgesic use.
- Trial name
- DDAM (NCT06650059)
- Testing
- Questionnaire
- Where
- 3 sites in France
- Volunteers
- 257 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Arthritis, Reactive, Arthritis, Rheumatoid
Prognostic Indicators and Determinants of the 2-5 Year Outcome in a Cohort of Early Synovitis Patients
This study will evaluate the 2-5 year outcome of a cohort of 250 patients with early synovitis, who were recruited into protocol 94-AR-0194 (The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis).
- Conditions
- Arthritis, Reactive, Arthritis, Rheumatoid, Synovitis
- Trial name
- NCT00001679
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Hepatitis C
Hepatitis C (HCV) Cure and Kidney Health
The purpose of this study is to learn how 12 weeks of HCV treatment with elbasvir and grazoprevir (brand name Zepatier) impacts your kidney function.
- Trial name
- NCT03407703
- Testing
- Elbasvir / Grazoprevir Oral Tablet [Zepatier]
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- San Francisco Veterans Affairs Medical Center
Colorectal Cancer
The Prognosis of Colorectal Cancer Patients After Indocyanine Green Fluorescence-guided Radical Surgery
Previous studies of Indocyanine green (ICG) in colorectal surgery have focused on lymphatic mapping, lymph node detection, and the number of harvested lymph nodes.
- Trial name
- NCT06508541
- Testing
- ICG Guided surgery, conventional surgery
- Where
- China
- Volunteers
- 235 people
- Sponsor
- Shanghai Tong Ren Hospital
Postpartum, Intrauterine Devices, Copper
Expulsion of Immediate Postplacental Copper Intrauterine Devices at Six Months: A Prospective Cohort Study
This is an observational study enrolling women who have had a copper intrauterine device placed immediately after childbirth. The study follows participants for 6 month in order to evaluate the primary outcome of IUD expulsion…
- Trial name
- PPIUD (NCT02706340)
- Testing
- No intervention - observational study only
- Where
- United States
- Volunteers
- 309 people
- Sponsor
- University of Pennsylvania
Ischemic Stroke
Prospective Cohort With Incident Stroke
The primary aim of the study is to derive and validate risk scores for vascular endpoints (recurrent stroke, myocardial infarction, and other complications of stroke) and for death following an incident stroke.
- Trial name
- PROSCIS (NCT01364168)
- Where
- 2 sites in Germany
- Volunteers
- 850 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Chronic Hepatitis B
The Establishment of Korean Hepatitis B Patients Cohort
According to the World Health Organization about 1,400,000 deaths reported annually, are related to chronic liver disease. Chronic liver disease is very prevalent in South Korea, placing a large economic burden nationwide.
- Trial name
- NCT04139850
- Testing
- Discontinuation of antiviral treatment in chronic hepatitis B cohort patients
- Where
- South Korea
- Volunteers
- 2,000 people
- Sponsor
- Yonsei University
ADHD, Language Disorders
Clinical Evaluation and Intervention of Developmental Behavioral Diseases Based on Multicenter Cohort Study(CEIDBDBMCS)
Diagnosis of Language Disorder and Attention Deficit Hyperactivity Disorder (ADHD) is difficult for several reasons. This study aims to establish a Chinese multi-center cohort for the early diagnosis of language disorder and ADHD…
- Trial name
- CEIDBDBMCS (NCT06025890)
- Testing
- Functional Training., Observe.
- Where
- China
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Chen Li
Carcinoma, Non-Small-Cell Lung, Immune-Related Adverse Events
PD-1 Immune Checkpoint Inhibitors and Immune-Related Adverse Events: a Cohort Study
The objective of our study is to assess the risk of immune-related adverse events associated with PD-1 inhibitors use compared to standard chemotherapy use in patients with non small cell lung cancer, using nationwide healthcare…
- Trial name
- NCT04115410
- Testing
- PD-1 inhibitor, Chemotherapy Drugs, Cancer
- Volunteers
- 4,724 people
- Sponsor
- Sungkyunkwan University
Sacral Fractures, Traumatic Unstable Sacral Fractures
Open Versus Minimally Invasive Fixation for Unstable Sacral Fractures in Adults
Severe injuries to the lower spine and pelvis, known as traumatic unstable sacral fractures, are complex injuries that often require surgery to stabilize the bones and prevent long-term disability.
- Conditions
- Sacral Fractures, Traumatic Unstable Sacral Fractures, Spinopelvic Dissociation, Pelvic Ring Injuries
- Trial name
- NCT07534579
- Volunteers
- 60 people
- Sponsor
- Assiut University
Unruptured Intracranial Aneurysm, Intracranial Bifurcation Aneurysm
Early Complications After Flow Diverter Versus Stent-Assisted Coiling for Unruptured Wide-Neck Intracranial Bifurcation Aneurysms
This prospective real-world cohort study aims to compare early postoperative complications between flow diverter treatment and stent-assisted coiling in patients with unruptured wide-neck intracranial bifurcation aneurysms.
- Conditions
- Unruptured Intracranial Aneurysm, Intracranial Bifurcation Aneurysm, Wide-Neck Aneurysm
- Trial name
- FD-SAC BAS (NCT07754188)
- Testing
- Flow Diverter, Stent-Assisted Coiling
- Where
- 3 sites in China
- Volunteers
- 274 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Mucormycosis
Mucormycosis in ICU
Mucormycosis is an invasive fungal infection affecting patients with various clinical conditions especially patients with heavy immunosuppression or patients with trauma or extensive burns.
- Trial name
- ZygoRéa (NCT03387696)
- Where
- 21 sites in France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Grenoble
Gynecologic Cancers
Feasibility Study of a Prospective and Pragmatic Cohort
Gynecologic cancers (cancers of cervix, endometrium, ovary, vagina, and vulva) represent an important part of the female cancer in France with more than 15 000 new cases in 2012.
- Trial name
- GYNEQOL-Pilot (NCT02864797)
- Testing
- Health related quality of life collected via CHES
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Breast Neoplasms
Cohort Study on Sequential ADC Therapy in HR-positive/HER2-negative Advanced Breast Cancer
The combination of cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) and endocrine therapy is the standard first-line treatment for advanced HR+ (hormone receptor-positive)/HER2- (human epidermal growth factor receptor 2-negative)…
- Trial name
- NCT07162259
- Testing
- First-line T-DXd followed by SG upon disease progression, First-line SG followed by T-DXd upon progression
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Yan Xue
HCC - Hepatocellular Carcinoma
A Prospective Observational Cohort Study on Dynamic CD8+ T-cell Profiling and Multi-omics Biomarkers for Predicting Conversion Therapy Response in Unresectable Hepatocellular Carcinoma
This study aims to identify early predictors for successful liver cancer treatment conversion. We will track changes in immune cells (CD8+ T-cells) in the blood during chemotherapy infusion (HAIC/TACE) combined with…
- Trial name
- NCT07117279
- Volunteers
- 120 people
- Sponsor
- Tongji Hospital
Urinary Tract Infection(UTI), Urinary Tract Infection, Recurrent
Multicentre Prospective Observational Cohort Study Aiming to Collect Medical Data, Create a Database to Facilitate Clinical and Fundamental Research Into Urinary Tract Infections With the Ultimate Goal of Improving Their Treatment.
The goal of this prospective observational study is to collect epidemiological, clinical, microbiological, genetic, and behavioral data on individuals with UTIs.
- Conditions
- Urinary Tract Infection(UTI), Urinary Tract Infection, Recurrent, UTI - Urinary Tract Infection
- Trial name
- IUTIC (NCT07485686)
- Where
- 5 sites in Germany, Netherlands and 1 more
- Volunteers
- 500 people
- Sponsor
- Angela HUTTNER
Cancer, Neoplasms
Safety and Pharmacokinetic Study of IT-141 in Monotherapy in Patients With Advanced Cancer
IT141 is a novel nanoparticle formulation of SN-38, the active metabolite of irinotecan, and is intended to deliver more drug to the tumor with reduced toxicity on normal tissues.
- Conditions
- Cancer, Neoplasms, Tumors, Refractory Solid Tumors
- Trial name
- NCT03096340
- Testing
- IT-141
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Intezyne Technologies, Inc.
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