Clinical trials: Cohort Study, open to volunteers
Postoperative Cognitive Dysfunction, Perioperative Neurocognitive Disorder
POCD After Major Gynecologic Surgery
This prospective observational cohort study aims to determine the incidence of early postoperative cognitive dysfunction (POCD) in patients undergoing major gynecological surgery.
- Trial name
- POCD-GYN (NCT07589348)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Fatihhan Zeytun
Gestatiaonl Diabetes Mellitus, Thyroid Disease Pregnancy
Gongji Pregnancy Endorine Cohort Study
To explore the relationship between genetic factors, lifestyle, and drug interventions and the occurrence, development, adverse pregnancy outcomes, and postpartum maternal-infant outcomes of gestational endocrine diseases.
- Conditions
- Gestatiaonl Diabetes Mellitus, Thyroid Disease Pregnancy, Hyperglycemia in Pregnant Diabetic Patients
- Trial name
- GREAT (NCT07125885)
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Shanghai General Hospital, China
Osteoporosis, Postmenopausal Osteoporosis
AGE Burden and Response to Antiresorptive Therapy in Osteoporosis
Osteoporosis is a common condition that increases the risk of bone fractures. Although antiresorptive treatments such as bisphosphonates and denosumab are effective in increasing bone mineral density, some patients continue to…
- Trial name
- NCT07329543
- Volunteers
- 240 people
- Sponsor
- Bursa City Hospital
PARKINSON DISEASE (Disorder)
Engage-PD: a Physical Activity Coaching Program Via Telehealth for People With Parkinson's Disease. A Single-cohort Study in Spain.
Engage-PD is a single cohort evaluation of implementation of a telehealth-delivered physical activity coaching program for people with early-mid stage Parkinson's disease in Spanish population.
- Trial name
- EngagePD-BCN (NCT07859332)
- Testing
- Physical Activity Coaching
- Volunteers
- 30 people
- Sponsor
- Hospital Clinic of Barcelona
Locally Advanced Gastric Cancer, Gastric Adenocarcinoma
The Safety and Efficacy of Robotic Assisted Surgery Using Vessel Sealer Extend in Locally Advanced Gastric Cancer
Gastric cancer is the fifth most common malignancy and the fourth leading cause of cancer-related deaths. Surgical resection is the primary treatment, with laparoscopic-assisted gastrectomy (LG) being a minimally invasive option.
- Trial name
- STARS-GC09 (NCT06881043)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Hospital of Jilin University
Prostate Cancer
Randomized Prospective Multi Center Cohort Study for Primary Diagnosis of Clinically Significant Prostate Cancer With Combination of PSA/DRE and Multi Parametric Magnetic Resonance Imaging
This randomized prospective multi center study is designed to confirm a new diagnostic pathway in primary diagnosis of clinically significant prostate cancer by combination of serum levels of prostate specific antigen (PSA)…
- Trial name
- PRIMA (NCT04993508)
- Testing
- PSA test, multiparametric prostate Magnetic Resonance Imaging (mpMRI), targeted MRI/US fusion-guided biopsy
- Volunteers
- 1,908 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Pancreatic Cancer Metastatic
A Single-center, Prospective, Two Cohort Study of Surufatinib Combined With AG or AG in the First-line Treatment of Locally Advanced or Metastatic Pancreatic Cancer
This is a single-center, prospective, two cohort study to evaluate the efficacy and safety of surufatinib in combination with AG or AG alone in the first-line treatment of patients with locally advanced or metastatic pancreatic…
- Trial name
- NCT05969171
- Testing
- Surufatinib, gemcitabine, nab-paclitaxel, Nab-paclitaxel, gemcitabine
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Fudan University
Polycystic Ovarian Syndrome (PCOS)
Comparative Study Between HOMA1-IR and HOMA2-IR in Prediction of Ovulation Outcome in Women With PCOS
122 women diagnosed with PCOS seeking fertility in the fertility clinic at kasr Alainy hospital will be subjected to Homeostatic model assessment for insulin resistance 1 was calculated for all participants through the equation…
- Trial name
- NCT06793904
- Testing
- Aromatase inhibitor Letrozole
- Where
- Egypt
- Volunteers
- 122 people
- Sponsor
- Cairo University
Alcohol Drinking, Suicide
mHealth-supported Skills Training for Alcohol-Related Suicidality
Suicide is a high priority public health problem and an increasingly prevalent alcohol-related consequence. One-third of people who die by suicide consume alcohol at hazardous rates in the year preceding death.
- Trial name
- mSTARS (NCT05847504)
- Testing
- mSTARS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Duke University
Preoperative Anxiety, Orthopedic Surgery
Preoperative Anxiety and One-year Patient-reported Outcomes in Orthopedic Surgery Patients Receiving Enhanced Recovery After Surgery or Conventional Care
This study investigates whether an Enhanced Recovery After Surgery (ERAS) program can help orthopedic surgery patients feel less anxious before their operation and recover better one year after surgery, compared to conventional…
- Conditions
- Preoperative Anxiety, Orthopedic Surgery, Patient Reported Outcome (PRO)
- Trial name
- ERAS-APO (NCT07706244)
- Testing
- Enhanced Recovery After Surgery (ERAS) pathway, Conventional care group
- Where
- Taiwan
- Volunteers
- 220 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Flexor Tendon Injury, Splints
Evaluation of Eight-Strand Flexor Tendon Repair Without Splinting
This prospective cohort study evaluates functional outcomes of primary eight-strand flexor tendon repair in zone II without postoperative splinting in 40 adults (≥18 years) at Assiut University Hospitals.
- Conditions
- Flexor Tendon Injury, Splints, Flexor Tendon Repair, Flexor Tendon
- Trial name
- NCT07382193
- Volunteers
- 40 people
- Sponsor
- Assiut University
Gallbladder Diseases, Cholelithiasis
Impact of Pringle Maneuver on Postoperative Gallbladder Diseases After Hepatectomy
The liver is an organ with a rich blood supply. During liver surgery (hepatectomy), surgeons often temporarily clamp the blood vessels supplying the liver to maintain a clear surgical field and reduce bleeding.
- Trial name
- NCT07452848
- Testing
- Pringle maneuver
- Where
- 8 sites in China
- Volunteers
- 2,000 people
- Sponsor
- West China Hospital
Pain, Chronic Pain
Chronic Pain After Combat-Related Traumatic Brain Injury (cTBI-Pain Study) A Prospective Cohort Study of Pain Chronification After Combat-Related Traumatic Brain Injury
Combat-related traumatic brain injury (cTBI), particularly blast-related injury, is frequently associated with the development of persistent and disabling chronic pain.
- Conditions
- Pain, Chronic Pain, Chronic Pain Due to Injury
- Trial name
- TBI-Pain (NCT07424248)
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Non-valvular Atrial Fibrillation (NVAF), Venous Thromboembolism (VTE)
Precision Antithrombotic Therapy
The goal of this observational study is to systematically analyze the relationship between trough/peak concentrations of novel oral anticoagulants (NOACs) and antiplatelet drugs with clinical events, aiming to provide high-level…
- Conditions
- Non-valvular Atrial Fibrillation (NVAF), Venous Thromboembolism (VTE), MI(Myocardial Infarction), Ischemic Stroke
- Trial name
- NCT07654634
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Calcaneal Fractures
Sustentaculum Tali Screw Fixation Mode and Postoperative Foot-Ankle Function in Calcaneal Fractures
This is an observational, ambidirectional cohort study. Calcaneal fractures are the most common tarsal bone fractures, and most are intra-articular fractures involving the subtalar joint.
- Trial name
- NCT07822698
- Testing
- Screw Tip Position Relative to the Sustentaculum Tali
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Peking University Third Hospital
Liver Cancer (Primary and Metastatic)
A Cohort Study (Risk Prediction of HCC in Patients With Chronic Liver Disease)
Evaluating the effectiveness of standardized HCC risk stratification management in improving early diagnosis rates in patients with chronic liver disease
- Trial name
- NCT07820644
- Where
- China
- Volunteers
- 15,000 people
- Sponsor
- Cai Qingxian
Sensorineural Hearing Loss, Bilateral Hearing Loss
Long-term Follow-up of a Cochlear Implant With Dexamethasone Eluting Electrode Array
A long-term follow-up of Cochlear's cochlear implant electrode array which passively elutes dexamethasone for a defined period of time to help reduce inflammatory responses.
- Trial name
- CI-DEX-LTFU (NCT06936449)
- Testing
- CI632D, CI632
- Where
- 3 sites in United States
- Volunteers
- 19 people
- Sponsor
- Cochlear
Lower Extremity Injury
Cohort Study of PPP Injections for Athletes With Muscle Injury
The investigators hypothesize that a single injection of platelet-poor plasma (PPP) into an acute muscle injury will significantly improve local muscle regeneration and patient outcomes compared to the standard of care using only…
- Trial name
- NCT07566039
- Testing
- Platelet Poor Plasma (PPP) Injection
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Colorado, Denver
Gout, Chondrocalcinosis
CRYSTALILLE Cohort: Getting the Whole Picture of Crystal-related Arthropathies
The objective of this research is to collect data to create an observatory of microcrystalline rheumatism (gout and calcium-crystal rheumatism) in patients treated at the Groupement des Hôpitaux de l'Institut Catholique de Lille…
- Conditions
- Gout, Chondrocalcinosis, Hydroxyapatite
- Trial name
- CRYSTALILLE (NCT04695028)
- Testing
- Data collection
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Lille Catholic University
Perioperative/Postoperative Complications, Anaphylaxis
Diagnosis and Allergen Identification of Perioperative Anaphylaxis
Perioperative anaphylaxis may lead to fatal respiratory and/or circulatory events, yet both clinical diagnosis and management are challenging.
- Conditions
- Perioperative/Postoperative Complications, Anaphylaxis, Tryptase, Allergens
- Trial name
- NCT06793163
- Where
- 6 sites in China
- Volunteers
- 115 people
- Sponsor
- Peking University First Hospital
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