Clinical trials: Coin Lesion, Pulmonary
Solitary Pulmonary Nodule
Tubeless VATS for Peripheral Lung Nodule
Chest tube placement after thoracoscopy surgery had been generally accepted as routine procedure for removal of the residual intrapleural fluid and air, however, it would cause post-operative pain, prohibit ambulation after…
- Trial name
- NCT02817048
- Testing
- chest tube, VATS without chest tube placement, VATS with chest tube placement
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Pulmonary Nodule, Multiple, Pulmonary Nodule, Solitary
Utility of CAML as Diagnostic for Early Stage Lung Cancer
Primary Objective Determine the prevalence of CAMLS in patients with pulmonary nodules. Secondary Objectives Determine the positive and negative predictive value of CAMLS in patients with pulmonary nodules who undergo biopsy.
- Trial name
- NCT03992183
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Fox Chase Cancer Center
Pulmonary Nodule, Solitary
Is Bronchoscopy Necessary in the Preoperative Workup of GGO Lung Cancer?(ECTOP-1005)
This study is one of Eastern Cooperative Thoracic Oncology Projects (ECTOP-1005). It aims to evaluate the role of flexible bronchoscopy in the pre-operative workup of ground glass opacity featured lung cancer.
- Trial name
- NCT03591445
- Testing
- Flexible Bronchoscopy
- Where
- China
- Volunteers
- 615 people
- Sponsor
- Fudan University
Pulmonary Neoplasms, Solitary Pulmonary Nodules
Diagnosis of Lung Lesions by Endobronchial Ultrasound With an Alternative Guide Sheath
The purpose of this study is to examine the usefulness of a balloon covered sheath as a guide sheath in endobronchial ultrasound guided transbronchial biopsy and bronchial brushing cytology for diagnosis of peripheral lung lesions
- Trial name
- NCT00922155
- Testing
- guide sheath
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Chang Gung Memorial Hospital
Solitary Pulmonary Nodule
Mobile Lung Nodule Observatory for Worldwide, Evidenced-based Research
Patients with lung nodules may develop a variety of potentially severe symptoms. These symptoms may impact a patient's quality of life and lead to difficult treatment.
- Trial name
- mLOWER (NCT02693496)
- Testing
- Installation or registration of smartphone application
- Where
- 34 sites in China
- Volunteers
- 10,000 people
- Sponsor
- Chinese Alliance Against Lung Cancer
Lung Cancer, Secondary Lung Cancer
Conventional Bronchoscopy Plus Rose Versus Electromagnetic Navigation (EMN) Plus Rose in Small Peripheral Lesions
The aim of this study is to evaluate if Electromagnetic navigation (ENB) in combination with rapid on site evaluation (ROSE) can improve diagnostic accuracy in those patients who fail to be diagnosed with conventional…
- Conditions
- Lung Cancer, Secondary Lung Cancer, Benign Lung Lesions
- Trial name
- NCT00880945
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Solitary Pulmonary Nodule, Oncology
18F-2-fluoro-2-deoxy-D-glucose in Positron Emission Tomography Computed Tomography
The study objectives are as follows: To determine the safety of trial 18F-2-fluoro-2-deoxy-D-glucose, produced by a new manufacturer, by surveillance for adverse events in patients having Positron Emission Tomography Computed…
- Conditions
- Solitary Pulmonary Nodule, Oncology, 18F-2-fluoro-2-deoxy-D-glucose, Adverse Event
- Trial name
- NCT04615156
- Testing
- 18F-2-fluoro-2-deoxy-D-glucose
- Volunteers
- 10,000 people
- Sponsor
- Eastern Health, Canada
Nodule Solitary Pulmonary, NSCLC
A Registry to Evaluate the Performance of the BDX-XL2 Test
The purpose of the ORACLE Registry is to demonstrate clinical utility of the BDX-XL2 test; specifically, the potential to reduce unnecessary invasive procedures, such as biopsies and surgeries, on benign lung nodules while not…
- Trial name
- ORACLE (NCT03766958)
- Where
- 15 sites in United States
- Volunteers
- 842 people
- Sponsor
- Biodesix, Inc.
Lung Cancer
Ultrathin Bronchoscopy for Solitary Pulmonary Nodules
The evaluation of solitary pulmonary nodules (SPN) requires a balance between procedure-related morbidity and diagnostic yield, particularly in areas where tuberculosis is endemic.
- Trial name
- Babyscope (NCT02490059)
- Testing
- bronchoscopy
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Pulmonary Nodule, Solitary, Multiple Pulmonary Nodules
GE Healthcare VolumeRAD Lung Nodule Detection Study
To perform a multiple reader, multiple case (MRMC) observer study assessing the detection performance of VolumeRAD tomosynthesis of the chest in detecting lung nodules.
- Trial name
- NCT00963651
- Testing
- Chest tomosynthesis and X-ray
- Where
- 4 sites in United States, Sweden
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- American College of Radiology - Image Metrix
Lung Tumor, Solitary Pulmonary Nodule
Feasibility of Multi-Energy Digital Radiography Detector for Lung Lesions Detection
A single-centre, industry sponsored, pilot study to assess the feasibility of Single Exposure Dual Energy Subtraction with a Multi-Energy digital radiography detector as an imaging platform for lung lesion detection.
- Trial name
- NCT03528733
- Testing
- Multi-Energy Digital Radiography Detector System
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- KA Imaging Inc.
Lung Nodule, Solitary, Lung Nodule
Iriscope for the Diagnosis of Peripheral Pulmonary Lesions: a Multicentre Randomised Controlled Trial
A pulmonary nodule is a small mass detected in your lungs during a scan. When a nodule is suspicious, we need to determine its nature (benign or malignant). To do this, a bronchoscopy is performed.
- Conditions
- Lung Nodule, Solitary, Lung Nodule, Lung Cancer (Diagnosis)
- Trial name
- NCT07798362
- Testing
- Use of Iriscope via guide sheath to guide biopsies, Bronchoscopy
- Volunteers
- 140 people
- Sponsor
- Erasme University Hospital
Pulmonary Nodule, Solitary, Whole-genome Methylation Sequencing
Benign/Malignant Pulmonary Nodule Classification Based on High-throughput Whole-genome Methylation Sequencing(GM-seq)
Lung cancer is the first cancer in China in terms of morbidity and mortality. The problem of early diagnosis/treatment has always been concerned.
- Trial name
- NCT05415670
- Testing
- Whole-genome Methylation Sequencing(GM-seq)
- Where
- 2 sites in China
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Geneplus-Beijing Co. Ltd.
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
Dynamic Evolution of Pulmonary Nodules and Influence Factors of Its Clinical Decision-making
The researchers are aimed to investigate the dynamic evolution of indeterminate pulmonary nodules by a long-term follow-up of patients with different characteristics.
- Trial name
- DEPICT (NCT04857333)
- Testing
- CT scan, Antibiotics, Surgical Resection
- Where
- China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- GuiBin Qiao
Yield of Cryo Biopsy in Lung Cancer, Solitary Pulmonary Nodule
EBUS Guided Cryo Biopsy of Solitary Pulmonary Nodules
To proof the feasibility and safety of EBUS guided transbronchial cryo biopsies in peripheral lung lesions
- Trial name
- NCT01221493
- Testing
- Cryo biopsy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Heidelberg University
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
Evaluate the Utility of the ProLung China Test in the Diagnosis of Lung Cancer
A Study to evaluate the utility of the ProLung China Test as an adjunct to CT scan in the diagnosis of lung cancer.
- Trial name
- ProLung (NCT02726633)
- Where
- 3 sites in China
- Volunteers
- 500 people
- Sponsor
- Chinese Alliance Against Lung Cancer
Pulmonary Nodules, Multiple, Pulmonary Nodules, Solitary
Differentiation of Benign and Malignant Pulmonary Nodules by Volatile Organic Compounds in Human Exhaled Breath
The goal of this observational study is to develop an advanced expiratory algorithm model utilizing exhaled breath volatile organic compound (VOC) markers.
- Conditions
- Pulmonary Nodules, Multiple, Pulmonary Nodules, Solitary, Lung Cancer
- Trial name
- NCT06518655
- Testing
- Gas chromatography-mass spectrometry(GC-MS) and micro Gas Chromatography-photoionisation detector (μGC-PID) system
- Where
- 15 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- ChromX Health
Pulmonary Nodule, Solitary, Lung Cancer
A Trial to Compare Robotic Assisted Bronchoscopy Ion's Clinical Utility for Peripheral Lung Nodule Access and Diagnosis to ENB
Multi-center randomized controlled study designed to compare the diagnostic yield of ION™ Endoluminal System with electromagnetic navigation bronchoscopy in patients undergoing transbronchial sampling procedure of peripheral…
- Trial name
- ARTICULAtE (NCT06308120)
- Testing
- Ion Endoluminal System, superDimension Navigation System and Accessories
- Where
- 3 sites in China
- Volunteers
- 354 people
- Sponsor
- Intuitive Surgical
Pulmonary Nodule, Multiple, Pulmonary Nodule, Solitary
Comparative Study on the Efficacy and Safety of Microwave Ablation and Lobectomy in the Treatment of Ground Glass Nodules Located in the Pulmonary Hilar Region
GGO is a characteristic focus of early lung cancer. Due to the abundant peripheral blood vessels and bronchial tissues around the GGO lesions located in pulmonary hilar, only lobectomy could be used for the surgical treat of…
- Trial name
- NCT05477251
- Testing
- microwave ablation, lobectomy
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Solitary Pulmonary Nodule, Lung Cancer
Bronchoscopic Approach to the Peripheral Lung Nodule - An Alternative Approach
Patients presenting with solitary or multiple lung nodules often require tissue confirmation in order to guide further management and determine if the lesion is benign or malignant.
- Trial name
- NCT00925210
- Testing
- Sequential pEBUS - ENB
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary