Clinical trials: Colchicine Adverse Reaction
HIV Infections, Inflammatory Markers
Efficacy and Safety of Low-Dose Colchicine on Surrogate Markers of Cardiovascular Events in People Living With HIV Receiving Antiretroviral Therapy
In a double-blind, randomized controlled trial, we assigned PLWH receiving ART without a history of cardiovascular events to received colchicine 0.6 mg once daily or placebo.
- Conditions
- HIV Infections, Inflammatory Markers, Colchicine Adverse Reaction
- Trial name
- NCT05168137
- Testing
- Low-dose colchicine
- Where
- Thailand
- Volunteers
- 84 people
- Sponsor
- Mahidol University
Renal Impairment, Gout
Evaluation of Colchicine and Nonsteroidal Anti-inflammatory Drug Combination Therapy and Renal Function in Gout Patients
Our findings are expected to provide real-world evidence of the renal-adverse effects of colchicine and NSAIDs combination therapy in patients with gout, which will guide healthcare professions in optimizing gout treatment…
- Conditions
- Renal Impairment, Gout, Colchicine Adverse Reaction, Nonsteroidals (NSAIDs)Toxicity
- Trial name
- NCT05006001
- Testing
- Colchicine and NSAID
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- En Chu Kong Hospital
Familial Mediterranean Fever (FMF )
The Effect of Probiotics on Response to Therapy and on Adverse Effect in Patients Treated With Colchicine for Familial Mediterranean Fever.
Colchicine is the drug of choice to treat patients with Familial Mediterranean Fever (FMF ), some of the patients treated with colchicine may suffer from gastrointestinal (GIT) adverse effect such as diarrhea and abdominal pain…
- Trial name
- NCT02021084
- Testing
- probiotic
- Sponsor
- Rambam Health Care Campus
Statin Adverse Reaction
Safety and Efficacy of LOw DOse COlchicine in Patients With STatin INTolerance: the LODOCO STINT Pilot Study
Statins are a class of cholesterol lowering medications that contribute to reducing a person's risk of experiencing a cardiovascular event like heart attack.
- Trial name
- NCT06874192
- Testing
- Low-dose colchicine at 0.5mg daily
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Virginia Commonwealth University
Atrial Fibrillation, Cardiac Surgery
Effect of Low Dose ColchiciNe on the InciDence of POAF
The prior End-AF study by the same group showed that 1 mg of colchicine didn't decrease the incidence of AF after cardiac surgery. The current study, End-AF Low Dose Study, will test 0.5 mg colchicine vs.
- Conditions
- Atrial Fibrillation, Cardiac Surgery, Colchicine Adverse Reaction
- Trial name
- END-AFLD (NCT03015831)
- Testing
- Colchicine
- Where
- 3 sites in Jordan
- Volunteers
- 254 people
- Sponsor
- Jordan Collaborating Cardiology Group
Colchicine, Inflammation in Cardiac Surgery
Colchicine's Effect on Inflammatory Markers
This study wants to see if the medicine colchicine can help lower inflammation and reduce the chance of developing an irregular heartbeat (atrial fibrillation) after heart bypass surgery.
- Conditions
- Colchicine, Inflammation in Cardiac Surgery, Post Operative Atrial Fibrillation, Inflammatory Markers
- Trial name
- NCT07287345
- Testing
- Colchicine (Colcrys®)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ayesha Ather
Colchicine Adverse Reaction, Atrial Fibrillation New Onset
COlchicine in Cardiac Surgery
Postoperative atrial fibrillation (POAF) is a major complication of cardiac surgery, which could lead to high morbidity and mortality, increase duration of hospital stay and increase the cost of treatment.
- Trial name
- COCS (NCT04224545)
- Testing
- Colchicine Pill
- Where
- 2 sites in Russia
- Volunteers
- 267 people
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery