Clinical trials: Cold
Birth
The Effect of Cold Application to the Sacral Area on Labor Comfort:
Purpose: Cold application is considered as an effective alternative treatment for labor comfort because of its low side effects and easy availability.
- Trial name
- NCT05693623
- Testing
- cold application
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Emine Yıldırım
COVID-19, Upper Respiratory Tract Infections
COVID-19 Prevention Trial: Effect of Prophylactic Use of TAFFIX™ on Infection Rate by SARS-CoV-2 Virus (COVID-19).
TAFFIX is a nasal powder spray that immediately creates a protective acidic barrier on the nasal mucosa against infection by inhaled viruses. The protective barrier lasts 5 hours.
- Trial name
- NCT05252468
- Testing
- TaffiX™
- Where
- Bulgaria
- Volunteers
- 693 people, healthy volunteers welcome
- Sponsor
- Nasus Pharma
Recurrent Upper Respiratory Tract Infections, Iron Deficiency Anemia
Iron Supplementation Outcome on Recurrent Upper Respiratory Tract Infections in 6-15 Years Old Egyptian School Children
Recurrent upper respiratory infections ( RURTIs) are common in school aged children. An adequate iron status might reduce their prevalence.
- Trial name
- NCT02398968
- Testing
- iron fumerate
- Where
- Egypt
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Covid19, Acute Respiratory Tract Infection
Trial of Vitamin D to Reduce Risk and Severity of COVID-19 and Other Acute Respiratory Infections
CORONAVIT is an open-label, phase 3, randomised clinical trial testing whether implementation of a test-and-treat approach to correction of sub-optimal vitamin D status results in reduced risk and/or severity of COVID-19 and…
- Trial name
- CORONAVIT (NCT04579640)
- Testing
- Vitamin D
- Where
- United Kingdom
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Cough
Efficacy and Safety of Zihua Wenfei Granules in Treatment of Postinfectious Cough (Wind-cold Invading Lungs Syndrome)
Cough is a common symptom of respiratory medicine clinic patients, which has complex etiology and wide-ranging. Cough is usually divided into three categories by time: acute cough, subacute cough and chronic cough.
- Trial name
- NCT05764668
- Testing
- Zihua Wenfei Zhisou Granule
- Where
- China
- Volunteers
- 480 people
- Sponsor
- DoCare Pharmaceutial Technology Co.,Ltd
Psychological
Mindset Interventions to Facilitate Taking Cold Showers
The primary objective of this trial is to determine whether mindsets sustain the feasibility of taking cold showers over a 3-month period.
- Trial name
- MICS (NCT05497713)
- Testing
- Mindsets
- Where
- Switzerland
- Volunteers
- 476 people, healthy volunteers welcome
- Sponsor
- Jens Gaab
Common Cold
Efficacy and Safety of the Combination of Acetylcysteine, Paracetamol and Phenylephrine for the Treatment of Common Cold
Prospective, randomized, multinational, multicenter, double-blind trial in 2 parallel groups of patients
- Trial name
- NCT05070650
- Testing
- Acetylcysteine, Paracetamol, Phenylephrine
- Sponsor
- Sandoz
Healthy
The Effect of Probiotics (L. Helveticus, B. Longum, and B. Bifidum) on Immune Function and Digestive Health
The purpose of this study is to determine if daily consumption of a probiotic in the period before, during and after academic exams will help maintain digestive and immune health and quality of life of undergraduate students.
- Trial name
- NCT01709825
- Testing
- Probiotic- Bifidobacterium Bifidum, Sugar Pill, Probiotic- Lactobacillus helveticus
- Where
- United States
- Volunteers
- 583 people, healthy volunteers welcome
- Sponsor
- University of Florida
Healthy Subjects
HEALSea Nasal Spray for Prevention of Infections in Children
Healsea® Children is a class IIa medical device. This is an isotonic seawater-based nasal spray supplemented with a natural Symbiofilm™ extract (0.02%) isolated from marine bacteria.
- Trial name
- HEALSPIC (NCT06582589)
- Testing
- Healsea Children
- Where
- 8 sites in Bulgaria
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Lallemand Pharma AG
Acute Rhinosinusitis, Allergic Rhinitis
An Observational Study to Evaluate The Relationship of Nasal Mucus Properties and Symptoms
This is a study to learn more about the common cold from studying the nasal secretions produced during a cold or episode of allergic rhinitis.
- Trial name
- NCT01553110
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Virginia Commonwealth University
Immune Health
Efficacy and Tolerability of Sensoril® in Improving Immunity and Thereby Reducing Incidence of Upper Respiratory Tract Infections
to assess the efficacy and safety of a standardized Withania somnifera extract (Sensoril®) as an immunomodulator in individuals suffering from recurrent URTIs.
- Trial name
- NCT04733924
- Testing
- Aqueous extract of roots plus leaves of Withania somnifera 125 mg, Aqueous extract of roots plus leaves of Withania somnifera 250 mg, Microcrystalline Cellulose
- Where
- 3 sites in India
- Volunteers
- 77 people
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Acute Upper Respiratory Tract Infection, Acute Bronchitis
Clinical Trials to Assess the Efficacy and Safety of HLIM
The purpose of this study is to assess the efficacy and safety of HLIM
- Trial name
- NCT03827590
- Testing
- Test, Active Comparator Control 1, Active Comparator Control 2
- Where
- South Korea
- Volunteers
- 487 people
- Sponsor
- SamA Pharmaceutical Co., Ltd
Cutaneous Manifestations, Skin Manifestations
Cutaneous Manifestations of Coronavirus Disease 2019(COVID-19).
An outbreak of Corona virus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-coV-2) occurred in Wuhan city, Hubei province, China in December 2019.
- Conditions
- Cutaneous Manifestations, Skin Manifestations, COVID-19, COVID-19 Pneumonia
- Trial name
- NCT05094687
- Where
- Pakistan
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Coronary Artery Bypass Surgery
Myocardial Protection With Multiport Antegrade Cold Blood Cardioplegia
In spite improvements in methods of myocardial protection, peri-operative myocardial damage is still the commonest cause of early morbidity and mortality after technically successful CABG Surgery.
- Trial name
- MACBC (NCT02303704)
- Testing
- multiport antegrade cardioplegia, Aortic root antegrade cardioplegia
- Volunteers
- 448 people
- Sponsor
- Chaudhry Pervaiz Elahi Institute of Cardiology
Acute Pain, Trauma
Determination of Analgesic Equipotent Doses of Inhaled Metoxyflurane vs. Intravenous Fentanyl
The aim of this study is to determinate the equipotent doses of inhaled metoxyflurane vs. intravenous fentanyl.
- Conditions
- Acute Pain, Trauma, Hypovolemia
- Trial name
- NCT03894800
- Testing
- Methoxyflurane (M), Fentanyl (F1), Fentanyl (F2)
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Non-Allergic Rhinitis With Eosinophilia Syndrome
Efficacy and Safety of Stapokibart in Non-Allergic Rhinitis With Eosinophilia Syndrome
The goal of this clinical trial is to learn if Stapokibart (CM310) works to treat Non-Allergic Rhinitis with Eosinophilia Syndrome (NARES) in adults. It will also learn about the safety of CM310.
- Trial name
- ESSNARES (NCT07240376)
- Testing
- Stapokibart (CM310)
- Where
- 11 sites in China
- Volunteers
- 90 people
- Sponsor
- Huazhong University of Science and Technology
Recurrent Herpes Labialis
An Open Label Study to Evaluate the Safety and Efficacy of BOR15001L7 for the Treatment of Cold Sores in Patients With Recurrent Herpes Labialis
BOR15001L7 is a natural product. The primary objective of this study is to demonstrate its non-inferiority to docosanol 10% based on the healing time of cold sores in patients with recurrent herpes labialis.
- Trial name
- NCT03977792
- Testing
- BOR15001L7, Docosanol Cream 10%
- Volunteers
- 164 people
- Sponsor
- Laboratoire Boreaderme Inc.
Resting Energy Expenditure, Thermogenesis
MIrabegron and Physiological Function in Cold Environments
Many Navy diving operations are performed in cold water. Despite technical advances to improve thermal protection for cold water diving, these applications are cumbersome and do not provide complete thermal protection as thermal…
- Conditions
- Resting Energy Expenditure, Thermogenesis, Brown Adipose Tissue
- Trial name
- NCT05990387
- Testing
- Mirabegron
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Indiana University
Acute Anterior Myocardial Infarction
Rapid Intravascular Cooling in Myocardial Infarction as Adjunctive to Percutaneous Coronary Intervention
Rapid MI-ICE-Pilot is designed to demonstrate the safety and efficacy of the Celsius Control™ System (CCS) endovascular catheter to reduce the infarct size resulting from acute anterior myocardial infarction when used in…
- Trial name
- NCT00417638
- Testing
- Endovascular cooling by the Celsius Control System, Standard of care
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- ZOLL Circulation, Inc., USA
Common Cold
Efficacy Trial of 3804-250A in the Prevention of Cold Illnesses
The purpose of this study is to evaluate the efficacy of 3804-250A in the prevention of the common cold. The study will also evaluate whether 3804-250A prevents rhinovirus infection, a virus that causes many common colds.
- Trial name
- NCT00762476
- Testing
- 3804-250A, 3804-291
- Where
- 2 sites in United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- The Dial Corporation