Clinical trials: Cold Intolerance
Cold Hypersensitivity
Efficacy and Safety of Sipjeondaebo-tang on Korean Patients With Cold Hypersensitivity in the Hands and Feet (SDT)
Gachon University, Gil Oriental Medicine Center
- Trial name
- NCT03374345
- Testing
- Sipjeondaebo-tang Granule
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Gachon University Gil Oriental Medical Hospital
Carpal Tunnel Syndrome, Entrapment Neuropathies
Nerve Entrapment in Diabetic Patients
The aim of this study is in a prospective, consecutive series of diabetic patients with carpal tunnel syndrome, who are then age and gender matched with non-diabetic patients having idiopathic carpal tunnel syndrome to compare…
- Conditions
- Carpal Tunnel Syndrome, Entrapment Neuropathies, Nerve Compression Syndromes, Diabetes Complications
- Trial name
- NCT00775333
- Testing
- Outcome after carpal tunnel release
- Where
- Sweden
- Volunteers
- 67 people
- Sponsor
- Skane University Hospital
Fibromyalgia
Pilot Study of Warm Acupuncture in Treatment of Cold-sensitive Fibromyalgia Syndrome
Non-pharmaceutical therapies, such as acupuncture, hydrotherapy, and meditative exercises (such as Qigong (including Tai Chi and Ba-Duan-Jin), have been shown to reduce pain and improve physical function.
- Trial name
- NCT05228990
- Testing
- warm acupunctrue
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Type 2 Diabetes Mellitus, Pre-diabetes
Acute Effects of Cold-induced Shivering on 24-hour the Glucose Profile in Metabolically Compromised Populations
Type 2 Diabetes Mellitus (T2DM) and its associated comorbidities pose a major health concern worldwide. Although lifestyle strategies, such as exercise and diet-induced weight loss are effective interventions to counteract the…
- Trial name
- SHIVER (NCT05576025)
- Testing
- Lifestyle intervention (cold exposure)
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Healthy, Obese
Circadian Rhythmicity in Cold-induced Thermogenesis
This study aims to investigate whether maximum cold-induced non-shivering thermogenesis (e.g. thermogenesis as a consequence of BAT activity) differs between morning and evening.
- Conditions
- Healthy, Obese, Glucose Intolerance
- Trial name
- COLDR (NCT04406922)
- Testing
- Personalized cooling protocol
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Hand Injuries and Disorders
Cross-cultural Adaptation and Validation of the CISS and the PWES Questionnaire in Patients With Hand Pathologies.
The primary objective of the study is to do translation, cross-cultural adaptation and validation of the CISS and PWES questionnaire in French. No available translation exist in French.
- Trial name
- NCT04646343
- Testing
- administration of F-CISS and F-PWES pre version, administration of definitive version of F-CISS and F-PWES plus F-DASH, F-HFS and F-SF 36
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Clinique Romande de Readaptation
Cold Intolerance
Botulinum Toxin Type A for Cold Intolerance Secondary to Digital Amputations and Replantations: A Pilot Study
Patients will be selected for cold intolerance after finger amputation or replantation. They will be given Botox or placebo dose as treatment and assessed over 3 months.
- Trial name
- NCT04917731
- Testing
- Botulinum toxin type A
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Upper Extremity Arterial Surgery
Long Term Patency Following Arterial Repair
Injury to the blood vessels of the extremities, and more specifically the arteries, can result from fractures and severe crush injuries. It occurs in about 3% of the general population.
- Trial name
- NCT02228057
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Pittsburgh
Spinal Cord Injuries (SCI), Orthostatic Hypotension, Dysautonomic
Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury
The study aims to explore how cardiovascular function changes in the first year after a spinal cord injury, and to see how different treatments, like spinal stimulation through the skin (transcutaneous spinal stimulation), affect…
- Conditions
- Spinal Cord Injuries (SCI), Orthostatic Hypotension, Dysautonomic, Cardiovascular, Transcutaneous Spinal Stimulation
- Trial name
- NCT06841198
- Testing
- spinal cord transcutaneous stimulation, Ice testing
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Cold Hypersensitivity, Vascular System Injuries
Treatment of Frostbite Sequelae With Botulinum Toxin A
Background Digital vasospasm as part of frostbite sequelae is comparable to the vasospastic disorders found in Raynaud's phenomenon which has been successfully treated with Botulinum toxin type A injections in the palm of the…
- Conditions
- Cold Hypersensitivity, Vascular System Injuries, Vibration; Disorder, Sensory Disorders
- Trial name
- NCT06460194
- Testing
- Botuinum toxin
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Raynaud's Phenomenon Secondary to Systemic Sclerosis
A Study to Assess the Effect of Oral Temanogrel on Digital Blood Flow in Adult Participants With Raynaud's Phenomenon Secondary to Systemic Sclerosis
The purpose of this study is to determine whether oral temanogrel improves digital blood flow in participants with Raynaud's phenomenon secondary to systemic sclerosis (SSc-RP) as a potential safe and effective treatment for…
- Trial name
- NCT04915950
- Testing
- Temanogrel
- Where
- 6 sites in United States, United Kingdom
- Volunteers
- 13 people
- Sponsor
- Pfizer
Cold Hypersensitivity
Efficacy and Safety of Ojeok-san on Korean Patients With Cold Hypersensitivity in the Hands and Feet
The Purpose of this trial is to investigate the efficacy and safety of Ojeok-san(OJS) on Korean Patients With Cold Hypersensitivity in the Hands
- Trial name
- OJS (NCT03083522)
- Testing
- Ojeok-San
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Chan-Yong Jeon
Sensory Restoration of the Reconstructed Finger Pulps, Cold Intolerance of the Reconstructed Finger
Nerve Transfer for Finger Sensory Reconstruction With Dorsal Branch of the Digital Nerve
A proper digital nerve (PDN) defect causes partial or complete sensory loss of the finger pulp, which results in functional disability.The dorsal branch of the PDN can be transferred for reconstruction of such nerve defects.In…
- Conditions
- Sensory Restoration of the Reconstructed Finger Pulps, Cold Intolerance of the Reconstructed Finger, Pain of the Reconstructed Finger
- Trial name
- NCT01559337
- Testing
- Nerve transfer
- Where
- China
- Volunteers
- 17 people
- Sponsor
- The Second Hospital of Tangshan
GI Patients on Oxaliplatin Containing Regimen
A Randomized Study to Establish the Efficacy of Oral Ice Exposure During Oxaliplatin Infusion in Preventing Oral Cold Sensitivity
The main purpose of this study is to evaluate whether exposure to ice chips in the mouth (oral ice chips) during oxaliplatin treatment prevents or reduces symptoms of cold sensitivity.
- Trial name
- NCT03427021
- Testing
- Oxaliplatin
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Syncope
Non-Pharmacologic Therapy for Neurocardiogenic Syncope
This study will examine whether certain procedures that do not involve the use of medications can reduce symptoms of neurocardiogenic syncope (SIN-ku-pe), or a condition involving recurrent fainting.
- Trial name
- NCT00096902
- Testing
- Tilt table test
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Hand Injuries
Cross-cultural Adaptation of the 'Cold Intolerance Severity Score' (CISS) to the Dutch Language.
To report Cold intolerance by the CISS score in medicolegal patients.
- Trial name
- Ciss-DLV (NCT05925907)
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Erasmus Medical Center
Orthostatic Hypotension
Autonomic Effects of Spinal Cord Stimulation in Spinal Cord Injury
The goal of this interventional crossover study is to determine the effects of transcutaneous spinal cord stimulation (TSCS) on the ability to perform moderate exercise and regulate core body temperature in the chronic spinal…
- Trial name
- NCT05960448
- Testing
- Transcutaneous Spinal Cord Stimulation (TSCS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Carbohydrate Intolerance
Effect of Genetic Variation in Starch-digesting Enzymes on Digestibility and Glycemic Index of Cold and Hot Rice
This study evaluates the effect of different methods of preparation (cooked and consumed hot vs cooked, cooled overnight and consumed cold) and variation in the activity of salivary amylase on the glycemic index and carbohydrate…
- Trial name
- NCT03667963
- Testing
- Glucose, Glucose plus lactulose, Hot Rice
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Toronto