Clinical trials: Cold Symptom
End Stage Renal Failure on Dialysis
Impact of Cold Dialysis in Combination With Intradialytic Exercise in Aspects Related to Quality of Life and Health
Despite the tremendous advances in dialysis technology, hemodialysis (HD) is a significant challenge for dialysis patients and quality of their lives[2].
- Trial name
- REACD (NCT03905551)
- Testing
- Cold Dialysis, Typical Dialysis, Exercise
- Where
- 3 sites in Greece
- Volunteers
- 72 people
- Sponsor
- University of Thessaly
Cryopyrin Associated Periodic Syndrome
The Safety and Efficacy of Canakinumab in Patients Aged 4 Years or Older Diagnosed With Cryopyrin-associated Periodic Syndromes (CAPS) in Canada
This study will assess the safety, tolerability and efficacy of canakinumab treatment in Canadian patient diagnosed with cryopyrin-associated periodic syndrome over a period of 18 months.
- Trial name
- NCT01105507
- Testing
- canakinumab (company code: ACZ885D)
- Where
- 2 sites in Canada
- Volunteers
- 4 people
- Sponsor
- Novartis Pharmaceuticals
Trauma, Hemorrhage
Cold Stored Platelet in Hemorrhagic Shock
The Cold Stored Platelet Early Intervention in Hemorrhagic Shock (CriSP-HS) trial is a proposed 3 year, open label, multi-center, randomized trial designed to determine the feasibility, efficacy, and safety of urgent release cold…
- Trial name
- CriSP-HS (NCT04667468)
- Testing
- Cold Stored Platelets (CSP), Standard Care
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Jason Sperry
Acupressure, Cold Application
Acupressure and Cold Application on Pain, Anxiety, Comfort, and Hemodynamic Parameters
The ventrogluteal injection is an invasive and often painful procedure commonly performed in healthcare settings. This study aimed to compare the effects of acupressure and cold application on pain, anxiety, comfort, and…
- Trial name
- NCT07049640
- Testing
- Acupressure Group, Cold Application to Acupressure Points Group
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Mardin Artuklu University
Cough
Clinical Trial of Efficacy and Safety of Levopront® 30 mg/5 ml in Patients With Dry Cough
Primary objective: To assess the efficacy of Levopront® in comparison with Libexin® based on daytime cough resolution rate by Day 8.
- Trial name
- LDP0114 (NCT03837938)
- Testing
- Levopront® syrup 30 mg/5 ml, Libexin®
- Where
- 8 sites in Russia
- Volunteers
- 184 people
- Sponsor
- Dompé Farmaceutici S.p.A
Leukemia
American Ginseng Extract in Preventing Respiratory Infection and in Reducing Antibiotic Use in Patients With CLL
RATIONALE: American ginseng extract may prevent or reduce acute respiratory illness in patients with chronic lymphocytic leukemia.
- Trial name
- NCT00752895
- Testing
- American ginseng
- Where
- 125 sites in United States
- Volunteers
- 293 people
- Sponsor
- Wake Forest University Health Sciences
Electrosurgery Versus Scalpel
Cold Knife Versus Monopolar Electrosurgery in Abdominal Incisions
the aim of work is to compare the early postoperative and late term wound complication rates between the scalpel and electrosurgery in patients with benign gynecological conditions undergoing abdominal incisions.
- Trial name
- NCT04236401
- Testing
- electrosurgery will be used for abdominal incision, scalpel will be used for abdominal incision
- Volunteers
- 90 people
- Sponsor
- Al-Azhar University
Hematologic Malignancy
Cold Versus Room Temperature Storage of Platelets for Bleeding in Hematologic Malignancy - a Pilot Trial
This is a pilot trial to discover the feasibility of recruiting 50 pts over the course of 12 months. The trial is testing the efficacy of using cold-stored vs.
- Trial name
- CoVeRTS-HM (NCT05820126)
- Testing
- Cold-stored platelet concentrate
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
Upper Respiratory Tract Infections
Efficacy of Diclofenac Potassium vs Nimesulide in the Treatment of Fever and Pain in Children With Upper Respiratory Tract Infection
This is a local, phase IV, open-label, randomized, head to head study of children aged 3 to 7 years. The objective of the study is to compare the efficacy of a single dose of both diclofenac potassium and nimesulide in the…
- Trial name
- NCT01257126
- Testing
- diclofenac potassium, nimesulide
- Sponsor
- Novartis Pharmaceuticals
Vasomotor Symptoms, Quality of Life
Determination of the Effects of Autogenic Relaxation Exercise and Cold Pillow Application on Vasomotor Symptom Control and Quality of Life in Postmenopausal Women
The aim of this study was to determine the effect of autogenic relaxation exercise and cold pillows on vasomotor symptom control and quality of life.
- Trial name
- Vasomotor (NCT05850338)
- Testing
- cold pad pillow, autogenic training
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Aylin Güneş
Allergic Disease, Chronic Spontaneous Urticaria
A Single Dose, Phase 1 Study of YH35324 in Patients with Various Allergic Diseases
This study aims to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) following a single subcutaneous injection of YH35324 in subjects with various allergic diseases.
- Conditions
- Allergic Disease, Chronic Spontaneous Urticaria, Chronic Inducible Urticaria, Cold Urticaria
- Trial name
- NCT05960708
- Testing
- YH35324, Omalizumab
- Where
- 9 sites in South Korea
- Volunteers
- 30 people
- Sponsor
- Yuhan Corporation
Percutaneous Coronary Intervention
Effect of Ice Bag Application to Femoral Region on Pain in Patients Undergoing Percutaneous Coronary Intervention
Background: Removal of femoral arterial catheter causes pain, and current interventions used for reducing this pain are not sufficiently effective.
- Trial name
- NCT03131271
- Testing
- cold application
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Inflammation, Familial Mediterranean Fever
Interleukin-1 Trap to Treat Autoinflammatory Diseases
Autoinflammatory diseases are illnesses characterized by episodes of inflammation that, unlike autoimmune disorders, lack the production of high titer autoantibodies or antigen-specific T cells.
- Conditions
- Inflammation, Familial Mediterranean Fever, Still's Disease, Adult-Onset
- Trial name
- NCT00094900
- Testing
- IL-1 Trap
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Ventilator Associated Pneumonia, Respiratory Tract Infection
Candida in the Respiratory Tract Secretions of Critically Ill Patients and The Efficacy of Antifungal Treatment
The purpose of the study is to determine whether the effect of treating Candida spp. isolated in the respiratory tract secretions of patients with a clinical suspicion of ventilator associated pneumonia (VAP) on clinical outcomes…
- Trial name
- CANTREAT (NCT00934934)
- Testing
- Normal Saline, anidulafungin
- Where
- 6 sites in Canada
- Volunteers
- 61 people
- Sponsor
- Daren K. Heyland
Chronic Inducible Urticaria
A Study to Investigate Efficacy, Safety, and Tolerability of Remibrutinib Compared With Placebo in Adults With CINDU Inadequately Controlled by H1-antihistamines
This is a Phase 3, parallel group, placebo-controlled, double-blind, confirmatory study in patients with CINDU, with an optional Open-label Extension (OLE).
- Trial name
- NCT05976243
- Testing
- Remibrutinib
- Where
- 130 sites in United States, Argentina and 26 more
- Volunteers
- 362 people
- Sponsor
- Novartis Pharmaceuticals
Cryopyrin-Associated Periodic Syndromes
Kineret CAPS Post Authorisation Study
A non-interventional, post authorization safety study to evaluate the safety of Kineret in the treatment of Cryopyrin Associated Periodic Syndromes (CAPS) in routine clinical care with regard to serious infections, malignancies…
- Trial name
- NCT02326376
- Testing
- anakinra (Kineret)
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 12 people
- Sponsor
- Swedish Orphan Biovitrum
Health Behavior
Cold Water Immersion in the Recovery of Markers of Muscle Damage of 10km Street Runners
Objective: To analyze the effect of cold water immersion (CWI) on the recovery of clinical, biochemical, functional and neuromuscular markers of muscle damage in 10 km street runners.
- Trial name
- NCT03094689
- Testing
- Cold water immersion, Water immersion
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Obesity
Chronic Intermittent Cold Exposure on Weight Loss
1. To test whether chronic intermittent cold exposure is more effective in programmed body weight loss when compared to conventional programmed weight loss. 2. To measure the metabolic responses (e.g.
- Trial name
- CICE (NCT01312090)
- Testing
- Whole body cryotherapy, counseling and behavioral therapy for weight loss
- Volunteers
- 20 people
- Sponsor
- Helsinki University Central Hospital
Pulmonary Disease, Chronic Obstructive
Prophylactic Antibiotic Treatment of Patients With Chronic Obstructive Lung Disease (COLD)
The purpose of the study is to investigate, in patients with moderate to severe chronic obstructive lung disease, whether intermittent antibiotic treatment leads to: A slower rate of decline in forced expiratory volume in one…
- Trial name
- NCT00132860
- Testing
- azithromycin
- Where
- Denmark
- Volunteers
- 800 people
- Sponsor
- Odense University Hospital
Tracheitis, Tracheobronchitis
Evaluation of Effectiveness of the Treatment After Repeated Administration of Klacid®SR
This post-marketing observational study (PMOS) will be conducted in a prospective, single-arm, single-country, multicenter format.
- Conditions
- Tracheitis, Tracheobronchitis, Bronchitis, Chronic Bronchitis
- Trial name
- NCT01130883
- Where
- 135 sites in Czechia
- Volunteers
- 3,130 people
- Sponsor
- Abbott