Clinical trials: Colectomy
Total Colectomy, Subtotal Colectomy
RISK FACTORS FOR ANASTOMOTIC LEAKAGE FOLLOWING TOTAL OR SUBTOTAL COLECTOMY (RIALTCOT)
Higher anastomotic leakage (AL) rate is reported after ileosigmoid (ISA) or ileorectal anastomosis (IRA) in total or subtotal colectomy (TSC) compared to colonic or colorectal anastomosis.
- Trial name
- RIALTCOT (NCT04512326)
- Testing
- Total or Subtotal colectomy
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Surgical Wound Healing, Botulinum Toxin, Type A
Botulinum Toxin Type A for Wound Healing After Laparoscopic Colectomy
This study aims to evaluate the efficacy and safety of botulinum toxin type A (BTX-A) injection as an adjunct to surgical wound healing in patients undergoing laparoscopic colectomy.
- Trial name
- NCT07795463
- Testing
- Botulinum toxin type A (Botox®, Allergan)
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Pham Ngoc Thach University of Medicine
Wound
Study of DERMABOND ProPen in Closure of Colectomy Wounds
2-octylcyanoacrylate (2-OCA) has been used extensively in clinical practice in trauma, plastic surgery, orthopaedic surgery, emergency medicine and paediatrics.
- Trial name
- NCT00978133
- Testing
- Dermabond ProPen (2-octylcyanoacrylate), Skin closure with skin staples
- Where
- Singapore
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Postoperative Ileus, Colon Cancer
Trial of Acupuncture for Reduction of Post-Colectomy Ileus
The purpose of this study is to see whether acupuncture may help patients recover from colon cancer surgery.
- Conditions
- Postoperative Ileus, Colon Cancer, Pain, Postoperative, Postoperative Nausea and Vomiting
- Trial name
- NCT00402961
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
to Evaluate the Effects of Clinical Hypnosis on Post-operative Pain, Following Colectomy Operations
Hypnosis for Colectomies as Postoperative Pain Management
The present study intends to assess the feasibility, value and direction of conducting a future, full scale randomised controlled trial, to evaluate the effects of clinical hypnosis on post-operative pain, following colectomy…
- Trial name
- Hypnopal (NCT06499909)
- Testing
- Hypnosis
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Somerset NHS Foundation Trust
Clostridium Difficile
Intestinal Lavage for the Treatment of Severe C. Difficile Infections
Clostridium Difficile infections (CDIs) are treated initially with antibiotic therapy and supportive care, with surgical intervention reserved for patients with significant systemic toxicity or perforation.
- Trial name
- NCT02466698
- Testing
- Intestinal Lavage, Vancomycin, PEG
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Analgesia, Post-Operative Pain
A Prospective Pilot Study of a Non-Narcotic Post-Operative Course After Colectomy
With this pilot investigation, the investigators aim to challenge the reliance on opiate analgesia following colon and rectal surgery.
- Conditions
- Analgesia, Post-Operative Pain, Breakthrough Pain, Colectomy
- Trial name
- NCT05200806
- Testing
- Non-Narcotic ERAS Post-Operative Pain Management
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Colon Cancer
Evaluation of NiTi Laparoscopic Compression Anastomosis Clip (LapCAC) Device for Intra-Corporeal Lap-Colectomy
The study involves adult subject requiring colonic anastomosis following laparoscopic intra-corporeal surgery. The anastomosis will be performed by using nitinilclip by the LapCAC device instead of staplers.
- Trial name
- NCT00250328
- Testing
- LapCAC Laparoscopic Compression Anastomosis Clip
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hadassah Medical Organization
Rectal Neoplasms, Colon Neoplasms
Fluorescent Evaluation of Colorectal Anastamoses
Bowel removal is indicated for various types of colon and rectal disease, including colon cancer, rectal cancer, diverticulitis, and inflammatory bowel disease among others.
- Conditions
- Rectal Neoplasms, Colon Neoplasms, Diverticulitis
- Trial name
- NCT01424293
- Testing
- Indocyanine Green, The SPY® Intraoperative Imaging System
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Maimonides Medical Center
Ileus
Does Chewing Gum After Elective Laparoscopic Colectomy Surgery Decrease Ileus?
The incidence of ileus after laparoscopic colectomy continues to pose complications for the patient, staff, and the healthcare system.
- Trial name
- NCT00632801
- Testing
- chewing gum
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- State University of New York - Upstate Medical University
Pain, Postoperative
The Interest of the Xylocaine® and Ketamine on the Management of Acute and Chronic Ain After Colectomy by Laparoscopy
Recent clinical studies in abdominal surgery have shown that the use of Xylocaine® parenterally intraoperative at plasma concentrations below the toxic threshold of 5 .mu.g / ml, had an analgesic effect and decreased…
- Trial name
- KETALIDO (NCT02969733)
- Testing
- Xylocaine, Ketamine, isotonic saline serum intravenous administration
- Where
- France
- Volunteers
- 135 people
- Sponsor
- University Hospital, Lille
Colon Cancer
Laparoscopic Versus Open Right Colectomy for Right Colon Cancer
The purpose of this research protocol is to compare open versus laparoscopic right colectomy (according to the CME technique of complete mesocolic excision) for right colon cancer.
- Trial name
- NCT05713903
- Testing
- Laparoscopic right colectomy, Open right colectomy
- Where
- Greece
- Volunteers
- 114 people
- Sponsor
- Larissa University Hospital
Minimal Invasive Surgery, Colon Surgery
The Anorectal Function and QoL of Patients Receiving Transrectal NOSE Via Rigid TAMIS Platform in Minimal Invasive Colon Surgery
The primary objective of this study is to prospectively determine and precisely estimate the incidence of Internal Anal Sphincter (IAS) Injury at 12 months following colectomy with Transrectal NOSE.
- Trial name
- NCT07653607
- Testing
- Pre-op and post-op anorectal function and quality of life evaluation
- Volunteers
- 57 people
- Sponsor
- Chang Gung Memorial Hospital
Bowel Disease
Bilateral TAP and RS Blocks Using Liposomal Bupivacaine/Bupivacaine vs. Regular Bupivacaine in Laparoscopic Colectomy
This study will be a single center, prospective triple blinded randomized controlled study, comparing the use of liposomal bupivacaine (Exparel) to regular bupivacaine with adjuncts in bilateral mid-abdominal transverse abdominis…
- Trial name
- TAPLIP (NCT05224089)
- Testing
- Liposomal Bupivicaine/Bupivacaine Admixture, Bupivacaine HCL
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Hartford Hospital
Adenomatous Polyps
Detection of Ileoanal Pouch/Reservoir Adenomas
The detection of adenomas is the basis for the follow-up of patients with familial adenomatous polyposis, after colectomy, with a remnant rectum or an ileal pouch. The optimal method for the adenomas detection is not defined yet.
- Trial name
- DARIAC (NCT05954949)
- Testing
- Adenomas detection rate with the different observation methods
- Volunteers
- 40 people
- Sponsor
- Jean Christophe Saurin
Solid Tumor, Colorectal Cancer
Live Biotherapeutic Product GB104 Phase 1 Study in Colorectal Cancer
Prospective, open label, multi-dose, sequential dose escalation, single-center, Phase 1 trial
- Conditions
- Solid Tumor, Colorectal Cancer, Sigmoid Colon Cancer, Rectosigmoid Junction Cancer
- Trial name
- NCT05943041
- Testing
- GB104(Level 1), GB104(Level 2), GB104(Level 3)
- Where
- South Korea
- Volunteers
- 9 people
- Sponsor
- GILongevity
Surgical Site Infection
Surgical-Site Infection After Laparoscopic Right Colectomy
Laparoscopic right colectomy with intracorporeal anastomosis seems to be associated with several short-term benefits. It could reduce the postoperative infection rate and shorten the hospital stay.
- Trial name
- NCT04350203
- Testing
- Laparoscopic right colectomy with intracorporeal anastomosis (IA), Laparoscopic right colectomy with extracorporeal anastomosis (EA)
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Hospital Plató