Clinical trials: Collagen Augmentation
Peri-implant Soft Tissue Deficiency, Insufficient Peri-implant Keratinized Tissue
CTG Versus Collagen Matrix for Peri-Implant Soft Tissue Augmentation
This randomized controlled trial compares two techniques for peri-implant soft tissue augmentation in the mandibular molar region: an autogenous connective tissue graft (CTG) and a collagen matrix.
- Trial name
- NCT07371481
- Testing
- Collagen Matrix, Connective Tissue Graft
- Where
- Vietnam
- Volunteers
- 46 people
- Sponsor
- Hanoi Medical University
ACL Tear
Augmentation of Anterior Cruciate Ligament Reconstruction Using Mesenchymal Stem Cells and Collagen Matrix Carrier
The goal of this observational study is to compare patient outcomes for reconstructive surgery of ACL tears. This study utilizes two randomized groups, one being the control group that receives standard ACL reconstructive…
- Trial name
- BioACL (NCT05582226)
- Testing
- ACL reconstruction, Mesenchymal stem cell implantation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Andrews Research & Education Foundation
Mucositis
Surgical Protocol for Prevention of Mucositis
The main goal of implant therapy is to obtain long-term peri-implant health. Among local risk factors in the etiology of peri-implant diseases the absence of keratinized tissue (KT) around the implant has been reported.
- Trial name
- NCT04628520
- Testing
- Free gingival graft, Collagen matrix, Maintenance
- Where
- Italy
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Survival, Prosthesis, Bone Loss
Osteotome-mediated Sinus Floor Elevation With or Without Grafting Material
Implant placement in the posterior part of the maxilla is frequently compromised or impossible due to atrophy of the alveolar process and pneumatisation of the maxillary sinus.
- Conditions
- Survival, Prosthesis, Bone Loss, Patient Satisfaction
- Trial name
- NCT04618900
- Testing
- Sinus floor elevation with a grafting material
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Edentulous Alveolar Ridge
Clinical Outcomes of Immediate Implants With or Without a Volume-stable Collagen Matrix
The purpose of this study is to evaluate the soft tissue clinical results in patients that received, or not, a soft tissue augmentation around dental implant inserted immediately after the extraction.
- Trial name
- NCT05081284
- Testing
- Volume-stable collagen matrix Geistlich Fibro-Gide®
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pisa
Bone Healing, Augmentation
Healing After Augmentation of Alveolar Ridge Using Collagen Membrane
One of the prerequisites for successful prosthetic implant therapy of patients is achieving the initial stability of the embedded implant, which largely depends on the width alveolar ridge, at the place of its installation.
- Conditions
- Bone Healing, Augmentation, Augmentation, Alveolar Ridge
- Trial name
- NCT06885983
- Testing
- implant placement, Guided bone regeneration
- Where
- Serbia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Posterior Mandible With Deficient Ridge Height
Vertical Ridge Augmentation With Autogenous Onlay Blocks Combined With Guided Bone Regeneration Versus Autogenous Bone Graft With Titanium Mesh in Posterior Mandible
Atrophic ridge augmentation utilizing guided bone regeneration (GBR) has become a major treatment option to provide optimal bone support for osseointegrated dental implants.
- Trial name
- NCT03680118
- Testing
- autogenous rings with GBR and autogenous graft with ti-mesh
- Volunteers
- 24 people
- Sponsor
- Cairo University
Soft Tissue Atrophy
Increasing the Thickness of Soft Tissues in the Esthetic Zone Around Implants
This is an interventional prospective randomized clinical trial (RCT) in parallel groups. This study is aimed at detecting a difference in the increase in the thickness of soft tissues of at least 0.3 mm between the two groups…
- Trial name
- NCT05551962
- Testing
- Soft tissue augmentation with CTG, Soft tissue augmentation with CM
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Peri-implant Soft Tissue Augmentation, Dental Implant Rehabilitation
Soft Tissue Augmentation Around Dental Implants
The goal of this study is to determine which method better increases the volume of soft tissues (gums) around dental implants: using the patient's own tissues or applying collagen matrices.
- Trial name
- NCT07605286
- Testing
- Connective Tissue Graft (Palate), Connective Tissue Graft (Tuberosity), Fibro-Gide Collagen Matrix
- Where
- Russia
- Volunteers
- 84 people
- Sponsor
- Andrey Vasilyev
Interdental Papilla Recession
Interdental Guided Creeping Technique
The aim of this randomized clinical trial is to treat interdental papillary deficiency with minimally invasive interdental guided creeping technique (IGCT) comparing collagen membrane versus connective tissue graft.
- Trial name
- NCT06264869
- Testing
- Interdental guided creeping technique (IGCT) and connective tissue graft (CTG), Interdental guided creeping technique (IGCT) and collagen membrane (CM)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- October 6 University
Soft Tissue Augmentation
The Use of a Porcine Collagen Matrix for the Prevention of Buccal Bone Wall Resorption During Implant Placement in the Aesthetic Zone.
Aim: To provide a comparative assessment of the clinical and radiographic effect of porcine collagen matrix when placed buccally at the time of single implant placement in the aesthetic zone vs autogenous connective tissue graft…
- Trial name
- NCT06622759
- Testing
- CTG, Collagen Matrix, Control group
- Where
- Greece
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Soft Tissue Atrophy
Using of Collagen Matrix for Maxillary Tuberosity Donor Area Preservation
An interventional prospective randomised clinical trial (RCT) in parallel groups is planned. The sample size was 30 patients who will be randomly divided into two groups based on the surgical procedure.
- Trial name
- NCT06039839
- Testing
- Closure of the donor area after CTG harvesting without the use of collagen matrix, Closure of the donor area after CTG harvesting with collagen matrix
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Horizontal Ridge Deficiency
Assessment of GBR in Augmentation of Horizontally Atrophic Maxillary Ridge Using Collagen Membrane Versus Using Titanium Mesh
this study is aiming to Assess postoperative complications and bone quality and quantity in augmentation of horizontally atrophic maxillary ridge using a 1:1 mixture of autograft and xenograft particulate bone covered with…
- Trial name
- NCT03635658
- Testing
- titanium mesh, collagen membrane (Sausage technique)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Ridge Augmentations
Socket Preservation: A Clinical and Histological Study
The objective of this study is to investigate the use of human amnion chorion membrane (BioXclude®) as an exposed barrier in ridge preservation and whether the intentional exposure of this membrane to oral environment will…
- Trial name
- NCT03422692
- Testing
- BioXclude amnion-chorion membrane, Mem-Lok collagenous membrane
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Kentucky
Non Therapeutic Body Modification
Post Market Safety Study and Effectiveness With Evolence in Subjects With Skin Color Types IV-VI
Approximately 165 subjects with Fitzpatrick Skin Color Types IV, V, and VI and a moderate to deep wrinkle between the corner of the nose and the corner of the mouth, will be treated with EVOLENCE® (an approved collagen filler) to…
- Trial name
- NCT00891774
- Testing
- EVOLENCE®
- Where
- 11 sites in United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Bone Loss, Alveolar
Effect of Collagen Versus PRF on BMA Osteogenic Potential
Utilization of collagen vs PRF membrane over the graft following sinus lift procedure and before suturing
- Trial name
- NCT05985317
- Testing
- Collagen membrane over BMAC/bovine graft in sinus lift, PRF membrane over BMAC/bovine graft in sinus lift
- Where
- Egypt
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cairo University
Keratinized Mucosa, Keratinized Tissue
Efficacy of Collagen Matrix for Peri-implant Soft Tissue Phenotype Modification
A stable band of keratinized mucosa (KM) around dental implants is thought to minimize tissue recession and provide resistance against mechanical, chemical, and microbial challenges, thereby preserving peri-implant tissue health.
- Trial name
- XCM versus FGG (NCT07056959)
- Testing
- Soft tissue substitute for peri-implant phenotype modification, Control Group - Free gingival graft for soft tissue augmentation
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Ridge Augmentation
Comparison of Non Perforated Titanium Foil Over Collagen Membrane in Ridge Augmentation.
Aim \& Objectives: The aim of the present study was to clinically and radiographically evaluate the efficacy of titanium foil and collagen membrane in ridge augmentation.
- Trial name
- NCT07162727
- Testing
- titanium foil in ridge augmentation, collagen membrane
- Where
- India
- Volunteers
- 18 people
- Sponsor
- Dr R Viswa Chandra
Achilles Tendon Rupture, Achilles Tendinopathy
Degenerative Achilles Tendon Rupture Repair With Regeneten Augmentation
Retrospective Case Series to investigate the effect a bovine collagen patch to augmented repair in acute Achilles tendon rupture with pre-existing tendinopathy
- Trial name
- NCT06252389
- Testing
- Achilles Tendon Repair augmented with Bioinductive Collagen Patch
- Where
- Hong Kong
- Volunteers
- 9 people
- Sponsor
- Chinese University of Hong Kong
Bone Loss, Missing Teeth
The Use of Bio-Oss Collagen for Sinus Augmentation Using the Transcrestal Approach.
To assess vertical bone height gain with Geistlich Bio-Oss Collagen used in conjunction with simultaneous implant installation in transcrestal approach sinus augmentation.
- Trial name
- NCT04581304
- Testing
- Geistlich Bio-Oss® Collagen, Geistlich Bio-Oss® Granules
- Where
- Israel
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus