Clinical trials: Collagen Augmentation
Recession, Gingival
Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation
The goal of this randomized clinical trial is to compare whether soft tissue augmentation placed in the donor site following a gum graft harvesting leads to volumetric changes compared to non-augmented sites in the palate.
- Trial name
- NCT05961566
- Testing
- Use of collagen matrix after subepithelial connective tissue graft harvest
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hailey Bivens
Soft Tissue Atrophy
Clinical and Histological Outcomes of Using Collagen Matrix or Soft Tissue Graft Around Implants
This was an interventional prospective randomized clinical trial (RCT) in parallel groups. The sample size is 35 patients who were randomly divided into two groups depending on the surgical intervention used.
- Trial name
- NCT05123898
- Testing
- Soft tissue augmentation
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Acellular Dermal Matrix, Bone Grafting
Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix
This investigator-initiated study will compare ADM and resorbable cross-linked collagen membrane barriers for guided bone regeneration at atrophic lateral ridge augmentation sites.
- Conditions
- Acellular Dermal Matrix, Bone Grafting, Soft Tissue Grafting
- Trial name
- NCT07613047
- Testing
- Guided Bone Regeneration with ADM (AlloDerm) as a barrier, Guided Bone Regeneration with Resorbable Crosslinked Collagen Matrix (Mem-Lok) as a barrier
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Tooth Loss, Soft Tissue Deficiency
A Clinical Study to Investigate Collagen Matrix 10808 for Soft Tissue Volume Augmentation Around Single Implants
The objective of this study is to investigate the safety and the function of the collagen Matrix 10808 in humans and to compare it versus the standard therapy, the transplantation of the autologous connective tissue graft.
- Trial name
- NCT02356770
- Testing
- Collagen Matrix 10808, Connective tissue graft
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Geistlich Pharma AG
Horizontal Deficiecy in Maxillary Arches
Horizontal Maxillary Ridge Augmentation With Sticky Bone Versus Collagen Membrane GBR
Guided bone regeneration (GBR) using bone graft and barrier membrane is a well-established technique for augmentation of atrophic alveolar ridges.
- Trial name
- NCT03697616
- Testing
- Ridge augmentation with sticky bone and GBR
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Resorption
Lateral Ridge Augmentation Around Implants
The rehabilitation of dentoalveolar defects and tooth loss has seen remarkable advancements over time. Extraction of tooth leads to reduction in physiologic dimension of bone and it is imperative to evaluate the site before…
- Trial name
- NCT04197128
- Testing
- Resorbable Collagen membrane with bone graft for augmentation, Ribose cross linked collagen matrix for augmentation
- Where
- India
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Dental Crowding, Gingival Recession
Evaluating the Clinical Efficacy of Collagen Scaffold (Ossix VOLUMAX) With Piezo-Surgical Decortication in Enhancing Orthodontic Treatment Outcomes: A Randomized Controlled Trial
Recent advances in orthodontic treatment have explored various materials to enhance treatment efficacy, particularly focusing on collagen scaffolds.
- Conditions
- Dental Crowding, Gingival Recession, Thin Phenotype
- Trial name
- NCT07097714
- Testing
- Piezocision with ribose cross-linked collagen matrix (Ossix® Volumax), control
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- NMSI DENTMASTER
Alveolar Bone Loss, Gingival Recession
Xenogenic Collagen Matrix vs. Connective Tissue Graft for Soft Tissue Augmentation Around Early Maxillary Implants
This study compares two methods used to improve gingival tissue around dental implants placed in (the maxillary esthetic zone). After a tooth is removed and a dental implant is placed early (usually 4-8 weeks later), additional…
- Conditions
- Alveolar Bone Loss, Gingival Recession, Peri-implant Mucositis
- Trial name
- NCT07024186
- Testing
- Xenogeneic Collagen Matrix, subepithelial connective tissue graft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Minia University
Alveolar Ridge Augmentation
Ridge Augmentation in Posterior Mandible Using Tunneling Technique With Amix of Autogenous Bone and Xenograft With and Without Collagen Membrane
aim Evaluation of the amount of bone gain following Ridge augmentation using tunneling technique in atrophic posterior mandibular ridges using anorganic bovine bone derived mineral mixed with particulated autogenous bone chips…
- Trial name
- NCT03712631
- Testing
- tunneling technique bone augmentation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Collagen Augmentation
Microfracture With/Without Collagen Augmentation in Patients Undergoing High Tibial Osteotomy
The quality of cartilage regeneration after marrow stimulation is well documented to be unpredictable, because they do not regenerate consistent amount of cartilage.
- Trial name
- NCT02685917
- Testing
- Microfracture without Collagen Augmentation, Microfracture with Collagen Augmentation
- Volunteers
- 30 people
- Sponsor
- The Catholic University of Korea
Missing Teeth
Enhancing Soft Tissues Around Inserted Implants by Two Different Methods
This randomized controlled clinical trial investigates the efficacy of xenogeneic collagen matrix (XCM) versus autogenous subepithelial connective tissue graft (SCTG) in enhancing the peri-implant soft tissue profile around…
- Trial name
- NCT06837688
- Testing
- Peri-implant soft tissue augmentation using connective tissue graft, Peri-implant soft tissue augmentation using xenogenic collagen matrix
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Damascus University
Bone Augmentation
Reconstruction of Atrophic Maxillary Ridges Using Mandibular Blocks With and Without Coverage Using Collagen Membrane
Is the use of collagen membrane on top of particulate bone mixture covered by onlay bone block in Maxilla better than the use of mixture of particulate bone covered by onlay bone block without the use of collagen membrane, in…
- Trial name
- NCT04462575
- Testing
- Onlay bone block covered using collagen membrane, Onlay bone block without collagen membrane
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Extraction, Tooth Replacement
Comparison of Two Collagen Membranes for Bone Augmentation Around Dental Implants Restored with Monolithic Zirconia Single Crowns
The goal of this randomized controlled clinical trial is to compare the use of two covering collagen membranes in a bone augmentation procedure around single implants and to assess three different veneering approaches on crowns…
- Trial name
- BioGide-Compr (NCT06724783)
- Testing
- Collagen membrane
- Where
- Switzerland
- Volunteers
- 68 people
- Sponsor
- Dr. med. dent. Malin Strasding
Chronic Ankle Instability, Ankle Sprain
Collagen Scaffold Bioaugmentation for ATFL Repair in Chronic Ankle Instability
This is a multicenter, randomized, controlled clinical trial comparing two surgical techniques for the treatment of chronic ankle instability (CAI).
- Conditions
- Chronic Ankle Instability, Ankle Sprain, Joint Instability
- Trial name
- REAR (NCT07878312)
- Testing
- Arthroscopic Anterior Talofibular Ligament Repair, Internal Brace Augmentation, REGENETEN Bioinductive Collagen Scaffold
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Alveolar Ridge Augmentation, Dental Implants
Lateral Ridge Augmentation Using a Volume Maintaining Collagen Scaffold Versus Allograft With Collagen Membrane.
The aim of the current study is to compare lateral bone augmentation using the current gold standard (FDBA plus resorbable collagen membrane) versus Ossix Volumax as a stand-alone material.
- Trial name
- NCT03457298
- Testing
- Ossix Volumax, FDBA with collagen membrane
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Bone Resorption Disorder
Guided Bone Regeneration in Atrophic Anterior Maxillary Ridges
This study is aiming to evaluate clinically, radiographically ,and histologically GBR using collagen membrane in combination with a mixture of ABBM and autogenous particulated bone compared to collagen membrane with ABBM in…
- Trial name
- NCT03731416
- Testing
- GBR by xenograft and autogenous bone
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Keratinized Mucosa
Keratinized Tissue Augmentation Using Porcine Collagen Matrix (Mucoderm®) Around Dental Implant
Aim of the Study To evaluate the using of porcine collagen matrix for keratinized tissue augmentation around delayed dental implant.
- Trial name
- NCT06753084
- Testing
- Alloderm
- Where
- 2 sites in Egypt
- Volunteers
- 22 people
- Sponsor
- ahmed amer
Sinus Lift Augmentation
Collagenic vs Collagen-enriched Graft in Sinus Elevation: RCT
The goal of this clinical trial is to histologically understand if collagenic or collagen enriched graft in sinus lift of healthy volunteers needing for implants in the posterior maxillae may work.
- Trial name
- C vs CE (NCT07386184)
- Testing
- transcrestal sinus lift
- Volunteers
- 24 people
- Sponsor
- Studio Odontoiatrico Associato Dr. P. Cicchese e L. Canullo
Ridge Deficiency
Comparison of Dehydrated Human Amnion-Chorion and Type 1 Bovine Collagen Membranes for Guided Bone Regeneration
The objective of this randomized clinical study was to evaluate the use of dehydrated human amnion-chorion membrane as an exposed barrier for guided bone regeneration (GBR) after tooth extraction and to determine whether…
- Trial name
- GBR (NCT03290638)
- Testing
- Guided Bone Regeneration (GBR)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Samer Faraj
Cognition, Inflammation Biomarkers
Dietary Supplements and Middle Aged Women (Collagen & Omega)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Inflammation Biomarkers, Bone Metabolism Biomarkers, Fatigue Symptom
- Trial name
- NCT07740967
- Testing
- Collagen peptides and omega-3
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Loughborough University