Clinical trials: Collagen Augmentation
Dehiscent Type of Alveolar Bone Defect, One Stage Bone Augmentation
Morphometric, Clinical and Histological Study on One Stage Bone Augmentation Using BoneCeramic (BCP) and Collagen Membranes
Prospective randomized assessment of alveolar ridge alterations after augmenting dehisced areas by applying principles of guided bone regeneration (GBR) subsequently to implant installation.
- Trial name
- BCP+Collagen (NCT00835432)
- Testing
- Ossix, Biogide
- Volunteers
- 40 people
- Sponsor
- Charite University, Berlin, Germany
Dental, Implant
Modified Periosteal Tissue Graft vs Collagen Matrix for Soft Tissue Augmentation Around Implants: A Comparative Study
This clinical trial aims to evaluate the effectiveness of the Modified Vascularized Interpositional Periosteal Connective Tissue Graft (mVIP-CTG) compared to Xenogeneic Collagen Matrix (XCM) around immediate implant in esthetic…
- Trial name
- NCT06808243
- Testing
- connective tissue graft, xenogenic collagen membrane
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Minia University
Alveolar Ridge Atrophy
HydroGraft for Mandibular Horizontal Ridge Atrophy Augmentation.
This randomized controlled trial aims to evaluate the efficacy of a hydrogel-enhanced allograft compared with a standard particulate allograft, both used in conjunction with a resorbable collagen membrane, for horizontal alveolar…
- Trial name
- NCT07865299
- Testing
- Control Arm (Allograft + Collagen Membrane), Study Arm (Hydrogel-enhanced Allograft + Collagen membrane)
- Volunteers
- 18 people
- Sponsor
- Damascus University
Guided Bone Regeneration, Bone Augmentation
Lateral GBR Using Two Types of Membrane With a Combination of Allograft-xenograft
Bone width is critical for successful implant placement, as thin bone increases the risk of bone loss. Various augmentation techniques-especially guided bone regeneration (GBR)-are effective in restoring bone volume using grafts…
- Trial name
- NCT07525128
- Testing
- Lateral Guided bone regeneration
- Where
- Lebanon
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Bone Loss, Alveolar
Evaluation of Vertical Bone Gain After Ridge Augmentation With APRF & Xenograft Vs Collagen Membrane & Xenograft. RCT
Comparative study for evaluation of vertical bone gain after one stage ridge augmentation with advanced platelet rich fibrin (A-PRF) and xenograft versus guided bone regeneration using collagen membrane and xenograft.
- Trial name
- NCT03855852
- Testing
- Xenograft and Collagen membrane, Xenograft and APRF
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Horizontal Ridge Deficiency
Vascularized Inter-positional Periosteal Connective-tissue Flap Versus Collagen Membrane in Guided Bone Regeneration
this study compares 2 techniques in guided bone regeneration for horizontal ridge augmentation in aesthetic zone
- Trial name
- VIP-CT (NCT05813340)
- Testing
- Vascularized inter-positional periosteal connective tissue flap
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Diseases
Xenogeneic Collagen Matrix as an Alternative to Free Gingival Grafting for Oral Soft Tissue Augmentation
A split-mouth study comparing soft tissue augmentation results using free gingival graft (FGG) versus xenogeneic collagen matrix (CM) for the generation of keratinized tissue (KT) around teeth with insufficient (< 2mm) KT.
- Trial name
- NCT01952301
- Testing
- Xenogeneic Collagen Matrix, Free Gingival Graft
- Volunteers
- 30 people
- Sponsor
- Perio Health Professionals, PLLC
Dental Papilla Loss, Black Triangles, Black Traingles
The Clinical Effects of Using Collagen Matrix in Papilla Augmentation: a Prospective Clinical Trial. Augmenting Fibro-Gide in Interdental Area Using Tunneling Technique to Treat Black Triangles (Papilla Loss)
Black triangles, also known as open gingival embrasures, are usually the result of the lack of papilla fill interdentally. With the improvement of dental procedures and materials, more attention has been directed to improving…
- Conditions
- Dental Papilla Loss, Black Triangles, Black Traingles, Interdental Papillae Reconstruction, Interdental Papilla Augmentation
- Trial name
- TPA (NCT06853704)
- Testing
- papillary unit advancement
- Where
- Jordan
- Volunteers
- 8 people
- Sponsor
- King Abdullah University Hospital
Loss of Teeth Due to Extraction, Alveolar Bone Loss
Regeneration of Alveolar Sockets With rhBMP-2-loaded Bovine Bone Mineral
Aim of the present investigation will be to evaluate the efficacy and safety of a granulate of rhBMP-2- loaded bovine bone mineral (rhBMP-2-BBM) as alveolar bone regeneration procedure following tooth extraction.
- Conditions
- Loss of Teeth Due to Extraction, Alveolar Bone Loss, Edentulous Alveolar Ridge
- Trial name
- PROTEOGRAFT (NCT05717478)
- Testing
- rhBMP-2-BBM, Bio-Oss+Bio-Gide
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Bone Loss
Lateral Ridge Augmentation Using Cross-linked or Non-cross-linked Collagen Membrane
The objective of the present trial is to test clinically, radiographically and histologically , in a lateral alveolar ridge augmentation model (without simultaneous implant placement) the efficiency in supporting bone formation…
- Trial name
- NCT04402671
- Testing
- non-cross-linked porcine skin collagen membrane, glutaraldehyde cross-linked bovine collagen membrane
- Where
- Lebanon
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Alveolar Bone Grafting, Bone Augmentation
Bone Augmentation Using Particulated Biomaterial and Autogenous Bone, Stabilized by Collagen Membrane and Pins (PaMP)
Twenty four patients with bone resorption on the anterior maxilla will be divided into two groups with different kinds of grafting: bone block associated with particulated biomaterial and particulated mixture of autogenous bone…
- Trial name
- PaMP (NCT02406924)
- Testing
- Biopsy, Computerized Tomography, Standardized periapical radiographs
- Volunteers
- 24 people
- Sponsor
- Pedro Tortamano
Bone Augmentation
Reconstruction of Deficient Maxillary Ridges Using Retromolar Blocks With and Without Collagen Membrane
Is the use of collagen membrane on top of particulate bone mixture covered by onlay bone block in Maxilla better than the use of mixture of particulate bone covered by onlay bone block without the use of collagen membrane, in…
- Trial name
- NCT06900933
- Testing
- Onlay bone block covered with collagen membrane, Onlay bone block without collagen membrane
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ridge Augmentation
Magnesium NOVAMag® Membrane vs. Collagen Jason® Membrane in Patients Requiring Guided Bone Regeneration
The NOVAMag® membrane is a medical device approved in the EU, and is a completely resorbable and biodegradable metal membrane. This medical device is used in the treatment of bone defects in the oral cavity.
- Trial name
- NCT06059898
- Testing
- GBR surgery including membrane placement, Biopsy
- Where
- 5 sites in Austria, Denmark and 1 more
- Volunteers
- 106 people
- Sponsor
- Botiss Medical AG
Edentulous Alveolar Ridge Atrophy, Soft Tissue Augmentation At Dental Implants
Cross-linked Volume-stable Collagen Matrix Versus Connective Tissue Graft At Implant Site.
Recent data suggested that an adequate volume of Keratinized Tissue (KT) around dental implant is a key factor to obtain aesthetic outcomes and to support easy long-term maintenance.
- Trial name
- NCT05458271
- Testing
- VCMX, CTG
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Florence
Maxillary Sinus Augmentation
Lateral Bony Wall Repositioning in Maxillary Sinus Floor Augmentation
The aim of the present prospective randomized controlled study is to clinically and histologically investigate the safety and efficacy of bony wall repositioning compared to rotary window preparation with membrane coverage in…
- Trial name
- NCT04811768
- Testing
- Maxillary sinus augmentation
- Where
- Hungary
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Ridge Augmentation, Bone Augmentation
Reconstruction of Deficient Atrophic Ridges Using Guide Bone Regeneration Technique
patients will be informed of the nature of the research work and informed consent will be obtained then randomized in 2 groups. Mixture 1:1 autogenous and xenogenic bone covered with Polytetrafluoroethylene membrane control group…
- Trial name
- NCT06746935
- Testing
- Collagen membrane., Polytetrafluoroethylene membrane.
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Buccal Defect At Implant Sites
Volumetric Assessment of Volume Stable Collagen Matrix in Soft Tissue Ridge Augmentation
This proposal suggests the use of a collagen scaffold as a core material for GBR in the case of a missing tooth between two existing teeth, in situations where there is sufficient bone to place an implant but a horizontal defect…
- Trial name
- NCT04873830
- Testing
- volume stable collagen matrix placement, connective tissue grafting
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Bone Regeneration, Dental Implants
Effectiveness of Different Membrane Applications in Vertical Ridge Augmentation
This randomized clinical trial (RCT) study investigates if there is any difference in absolute vertical bone gain between perforated dense-polytetrafluroethylene (d-PTFE) mesh vs perforated d-PTFE mesh covered with a native…
- Conditions
- Bone Regeneration, Dental Implants, Polytetrafluoroethylene
- Trial name
- NCT04843488
- Testing
- Guided bone regeneration with a PTFE membrane, Guided bone regeneration with a PTFE+collagen membrane
- Where
- Hungary
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Urban Regeneration Institute
Surgery
Buccal Graft + Collagen Matrix Versus Free Gingival Graft for Keratinized Mucosa Augmentation at Implant Sites
The study aims at comparing two different approaches for soft tissue augmentation at implants lacking keratinized and adherent mucosa width: the free gingival graft (FGG) vs the Buccal Strip Graft in combination with a xenogeneic…
- Trial name
- FGGvsBSG+CM (NCT05844475)
- Testing
- Conventional Free Gingival Graft Approach (FGG), Buccal Strip Graft with a collagen matrix (bSG + CM)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Ridge Augmentation
Autogenous Sticky Bone Plus Platelet-rich Fibrin Membrane Versus Xenograft With Collagen Membrane for Posterior Atrophic Mandible
Background: Teeth loss in the posterior mandible initiates residual ridge resorption, this causes difficulty in implant placement so ridge augmentation must be done either simultaneous with implant placement or in a staged…
- Trial name
- NCT07825896
- Testing
- autogenous sticky bone + PRF membrane, Xenograft + collagen membrane
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University