Clinical trials: Colon Cancer Patients
Colorectal Cancer
Attitudes Towards Prophylactic Colectomy in Hereditary Non-polyposis Colorectal Cancer (HNPCC) Patients
The purpose of this study is to learn more about individual's with a family history of colon cancer and the process by which they may decide to undergo or not undergo prophylactic colectomy.
- Trial name
- NCT00582452
- Testing
- Telephone survey
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Diabetes Risk, CVD Risk
Effectiveness of a Self-health Assessment Mobile Application in Young-to-midlife Adults in Hong Kong
This project aims to compare the effectiveness of Wellnuts, an evidence-based, algorithm-driven self-health assessment mobile application, in empowering asymptomatic young-to-midlife adults in Hong Kong, promoting health…
- Conditions
- Diabetes Risk, CVD Risk, Colorectal Cancer, Lung Cancer
- Trial name
- NCT07720245
- Testing
- Wellnuts app intervention, Web-based health resources
- Where
- Hong Kong
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Lynch Syndrome, Li Fraumeni Syndrome
Video Capsule Examination in Patients With Lynch Syndrome
Surveillance for colorectal cancer (CRC) in patients predisposed to develop CRC during their lifetime has been impacted by access to colonoscopy suites and endoscopy specialists in the past couple of years.
- Conditions
- Lynch Syndrome, Li Fraumeni Syndrome, PTEN Hamartoma Syndrome, FAP
- Trial name
- PILLCAM (NCT06712095)
- Testing
- Video capsule investigation
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Colo-rectal Cancer
Decision Counseling and Follow-up for Shield+ Patients
Prospective, observational, minimal-risk study evaluating decision-making, decisional conflict, intention to undergo complete diagnostic evaluation (CDE), and colonoscopy completion after a positive Shield TM blood-based…
- Trial name
- DCaF (NCT07620535)
- Testing
- Decision Counseling Session
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Guardant Health, Inc.
Colorectal Cancer
Chemotherapy-Related Changes in Neurocognitive Function and Symptoms in Colorectal Cancer Patients: A Pilot Study
Cancer treatments have successfully improved cancer outcomes but frequently negatively impact quality of life in cancer survivors.
- Trial name
- NCT03683004
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Clinical Response, Toxicity
Study of Metronomic Capecitabine and Oxaliplatin Versus XELOX in Egyptian Metastatic Colorectal Cancer Patients
Colorectal cancer (CRC) in Egypt is advanced tumors at diagnosis. Although, the dramatic increase in efficacy, reduction of mortality, and improvements in survival by the use of standard doses of chemotherapy, some CRC patients…
- Conditions
- Clinical Response, Toxicity, Survival
- Trial name
- NCT04425564
- Testing
- metronomic XELOX, Classic XELOX, Blood samples for pharmacological studies
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Prevention, LARS - Low Anterior Resection Syndrome
Effectiveness of Pelvic Floor Exercise to Prevent LARS (Low Anterior Resection Syndrome)
The main aim of this randomized study will be to determine the effectiveness of pelvic floor exercises on the incidence or severity of LAR syndrome in patients after mini-invasive rectal resection.
- Conditions
- Prevention, LARS - Low Anterior Resection Syndrome, Pelvic Floor Disorders, Rectal Cancer
- Trial name
- CH1 (NCT06519006)
- Testing
- Pelvic floor exercise
- Where
- Slovakia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- F. D. Roosevelt University Hospital
Colon Cancer Screening, Colon Cancer Surveillance
Enchasing Polyp Detection: The Effect of Adding Polyp Detection Attachment Device to Computer Aid Detection System.
Despite the widespread use of colonoscopy, the ongoing challenge of potentially missing polyps remains. Previous studies have independently shown that both Endocuff, a colonoscope attachment device for polyp detection, and…
- Trial name
- NCT06116864
- Testing
- Endocuff and GI Genius, GI Genius
- Where
- United States
- Volunteers
- 1,766 people, healthy volunteers welcome
- Sponsor
- Marshall University
Colorectal Cancer
Colorectal Cancer Screening French Organizations for the Follow-up After Colonoscopy
France is one of the European countries where the incidence of colorectal cancer is the highest among cancers for both sexes. Fecal occult blood screening has been implemented since 2008.
- Trial name
- Tempo-colo (NCT03383367)
- Testing
- Tempo Colo
- Where
- France
- Volunteers
- 33,000 people, healthy volunteers welcome
- Sponsor
- Association pour le Dépistage Organisé des Cancers dans le Rhône
Preference, Patient, Pharmacist-Patient Relations
Preferences of Patients Treated With Oral Cancer Drugs and Informal Caregivers for Pharmaceutical Consultation in Hospital
To ensure the safe use of oral anticancer drugs, oncology pharmacy consultations (OPCs) have been established in France. Their goal is to provide the patient with the means to identify, prevent and limit adverse effects and to…
- Conditions
- Preference, Patient, Pharmacist-Patient Relations, Caregiver, Cancer
- Trial name
- IMPLICATION (NCT05970471)
- Where
- France
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Metastatic Colorectal Cancer
FOLFOX + Panitumumab According to a "Stop and go" Strategy With a Reintroduction Loop After Progression on Fluoropyrimidine as Maintenance Treatment, as the First Line in Patients With Metastatic Colorectal Adenocarcinoma Without a RAS Mutation
Single-arm, multi-centre phase II study The primary objective is to evaluate the time to failure of the strategy.
- Trial name
- OPTIPRIME (NCT03584711)
- Testing
- FOLFOX + panitumumab
- Where
- 124 sites in France, Martinique
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Federation Francophone de Cancerologie Digestive
Lynch Syndrome, Contraception
Perception About Benefits and Risks Related to Combined Hormonal Contraceptives Use in Patients With Lynch Syndrome
Combined hormonal contraceptives (CHCs), according to the opinion by The Manchester International Consensus Group, should be considered for women wishing contraception because also positively impact endometrial cancer and ovarian…
- Trial name
- NCT05909410
- Testing
- Survey investigating the CHC use and patients' perception about the relationship between CHC and cancer, diseases and symptoms
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Piazza della Vittoria 14 Studio Medico - Ginecologia e Ostetricia
Evaluation of the Effects of Education Provided on Family Members Caring for Colorectal Cancer Patients
The Effect of Education Provided to Family Members Caring for Colorectal Cancer Patients on Caregiving Reactions and Healthy Lifestyle Behaviors: A Prospective Quasi-experimental Study.
The effect of education provided to family members caring for colorectal cancer patients on caregiving reactions and healthy lifestyle behaviors: A prospective quasi-experimental study
- Trial name
- NCT04791982
- Testing
- Educational sessions
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara University
Gastrointestinal Disease, Colorectal Cancer
Randomized Controlled Study Comparing Colon Evaluation With The Pure-Vu System To A Standard Colonoscopy In Patients Who Are High Risk For Inadequate Bowel Preparation
The primary objective of this multi-center, prospective, randomized controlled trial is to evaluate the bowel cleansing after Pure-Vu use in outpatient subjects at high risk for inadequate colon preparation as compare to standard…
- Trial name
- RESCue (NCT04285008)
- Testing
- Pure-Vu System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Colorectal Neoplasms
Risk-adapted Screening in First-degree Relatives of Patients With Colorectal Cancer
BACKGROUND: First-degree relatives of patients with colorectal cancer are at increased risk for colorectal cancer as well. Nevertheless, participation in the German national screening program stagnates at 2-3 percent per year…
- Trial name
- FAMKOL (NCT01903395)
- Testing
- Nurse-led counselling
- Where
- 33 sites in Germany
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Colorectal Cancer
Uncovering and Overcoming the Barriers of Colorectal Cancer Screening Amongst Spouses of Patients With Colorectal Cancer
To determine amongst spouses of colorectal cancer patients: 1. Screening rates for Colorectal Cancer (CRC) amongst spouses of patients with CRC 2. Barriers to screening based on the Health Belief Model (HBM) 3.
- Trial name
- NCT04544852
- Testing
- Current practice, Targeted intervention programme
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University Health System, Singapore
Metastatic Colorectal Cancer
Re-challenge of Anti-EGFR for Patients With RAS/BRAF Wild-type Metastatic CRC
The aim of the trial is to study the efficacy and safety of Cetuximab re-challenge for Chinese Patients with RAS/BRAF wild-type Metastatic Colorectal Cancer.
- Trial name
- NCT04224415
- Testing
- C225+CPT-11
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Yuhong Li
Colorectal Cancer
Efficacy and Patient Satisfaction of Miralax and Gatorade Versus Movi Prep
This study will be comparing patient satisfaction, efficacy comparing miralax with gatorade versus Movi Prep for outpatient colonoscopy.
- Trial name
- NCT01695863
- Testing
- comparing 2 drugs on their effect on the bowel preparation for colonoscopy
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Malignant Female Reproductive System Neoplasm, Malignant Hepatobiliary Neoplasm
Acceptance and Commitment Therapy in Improving Well-Being in Patients With Stage III-IV Cancer and Their Partners
This pilot clinical trial studies how well acceptance and commitment therapy works in improving well-being in patients with stage III-IV cancer and their partners.
- Conditions
- Malignant Female Reproductive System Neoplasm, Malignant Hepatobiliary Neoplasm, Partner, Stage III Breast Cancer
- Trial name
- NCT03112668
- Testing
- Cognitive Behavior Therapy, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Colorectal Cancer, Cancer Cachexia
Structural Characteristics of Trunk and Limb Muscles in Cachectic Colorectal Cancer Patients
Until now, cancer is still associated with high morbidity and mortality, and is therefore a big issue for the public health. Colorectal cancer is the second leading cause of cancer death in developed countries.
- Trial name
- CTLm-CCP (NCT06780423)
- Testing
- Minimal invasive fine needle muscle biopsies
- Where
- 2 sites in Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hasselt University