Clinical trials: Colon Cleansing
Colorectal Cancer
Pharmacodynamic Evaluation of Stool Output Following Oral Administration of Various Low Volume PEG3350-based Gut Cleansing Solutions Using the Split Dose Intake in Healthy Subjects
This study is to investigate the effect of various modified low volume polyethylene glycol (PEG) 3350 and ascorbic acid/ascorbate (PEG+ASC)-based gut cleansing solutions on stool output in healthy subjects.
- Trial name
- OUT (NCT01834742)
- Testing
- NER1006, Moviprep
- Where
- 2 sites in Romania
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Norgine
Capsule Endoscopy
Small Bowel Cleansing for Capsule Endoscopy in Pediatric Patients
The primary aim of this prospective, randomized and controlled study was to evaluate the effect of five bowel preparation regimens on small-bowel cleansing in a pediatric population.
- Trial name
- PREP-CE (NCT01783782)
- Testing
- DIET, polyethylene glycol 4000 solution with simethicon, simethicon
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Policlinico Umberto I
Colorectal Neoplasms
Comparison of the Effectiveness of Bowel Preparations Before Colonoscopy
Polyethylene glycol is the gold standard of bowel preparation for colonoscopy. The most important disadvantage is high volume of this preparation.
- Trial name
- NCT03242369
- Testing
- colonoscopy
- Where
- Czechia
- Volunteers
- 400 people
- Sponsor
- Military University Hospital, Prague
Colon Cleansing
PMC Split Preparation for Colon Cleansing
This is an endoscopist-blinded, prospective, multicenter study involving adult outpatients aiming at evaluating whether sodium picosulphate/magnesium citrate split dosing is associated to higher efficacy and acceptability in…
- Trial name
- MAGIC-P (NCT01909219)
- Testing
- Sodium picosulphate/magnesium Citrate
- Where
- 2 sites in Italy
- Volunteers
- 862 people, healthy volunteers welcome
- Sponsor
- Luigi Sacco University Hospital
Preparation for Colonoscopy
Safety and Efficacy of High Dose Bowel Preparation Solutions for Patients With Difficult To Clean Colons For Colonoscopy
The purpose of this study is to document the safety and effectiveness of high doses of liquids to clean the colon for colonoscopy in patients who had a previous colonoscopy with a poorly cleaned colon.
- Trial name
- NCT02661750
- Testing
- Bowel Preparation
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Gastroenterology Services, Ltd.
Colon Cleansing for Colonoscopy
Sodium Picosulphate/Magnesium Citrate and Low-volume PEG -Ascorbic Acid as Preparation for Colonoscopy
Adequate bowel cleansing is essential for effective colonoscopy. Acceptance of colon preparation affects the quality of colon cleansing.
- Trial name
- NCT01603654
- Testing
- sodium picosulphate magnesium citrate, low-volume PEG -ascorbic acid
- Where
- 3 sites in Italy
- Volunteers
- 300 people
- Sponsor
- ASST Fatebenefratelli Sacco
Bowel Preparation
Effect and Safety of Polyethylene Glycol Combined With Linaclotide on Colon Cleansing for Patients With Chronic Constipation
Constipation is a common reason of poor bowel preparation, which negatively influences the quality of colonoscopy. Clinically to explore more effective and tolerant bowel clearance programs is necessary for patients with chronic…
- Trial name
- NCT05137145
- Testing
- Linaclotide, Compound Polyethylene Glycol Electrolyte Powder
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Colorectal Cancer, Colorectal Carcinoma
Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 Versus a Sodium Picosulfate and Magnesium Salt Solution Using Day Before-Only Dosing Regimen in Adults.
This study evaluates the efficacy, safety and tolerability of NER1006 versus a sodium picosulfate and magnesium salt solution (SP + MS) in adult patients requiring bowel cleansing prior to any procedure that requires a clean…
- Conditions
- Colorectal Cancer, Colorectal Carcinoma, Colon Cleansing
- Trial name
- NCT02273141
- Testing
- NER1006, Day Before-Only Dosing, SP+MS, Day Before-Only Dosing
- Where
- 19 sites in Germany, Italy and 4 more
- Volunteers
- 515 people
- Sponsor
- Norgine
Bowel Preparation Before Colonoscopy
A Trial to Evaluate the Efficacy and Safety of PMF104 Compared to a Conventional PEG-electrolyte Solution in Children
A randomised, single-blind, active controlled, multi-centre trial to evaluate the efficacy, safety, tolerability, acceptability and palatability of PMF104 compared to a conventional PEG-electrolyte solution in paediatric subjects…
- Trial name
- NCT03106922
- Testing
- PMF104, Klean-prep
- Where
- 9 sites in Belgium, France and 1 more
- Volunteers
- 430 people
- Sponsor
- Alfasigma S.p.A.
Colon Cleansing
Efficacy and Safety Study of Sodium Phosphate Tablets vs PEG for Bowel Cleansing
The purpose of this study is to evaluate the efficacy and safety of sodium phosphate tablets compared to split dose of 4 liters of PEG used in adults for bowel cleansing prior to colonoscopy.
- Trial name
- NCT01840553
- Testing
- oral sodium phosphate tablets, polyethylene glycol
- Where
- 19 sites in France, Germany and 1 more
- Volunteers
- 461 people
- Sponsor
- Laboratoires Mayoly Spindler
Colonoscopy
Impact of a Self-Administered Information Leaflet on Adequacy of Colonic Cleansing for in-Hospital Patients
The quality of colon cleansing has a major impact on efficiency and cost of colonoscopy. A hand-out was made to instruct and motivate patients to adequately clean the bowel before colonoscopy.
- Trial name
- NCT00160823
- Testing
- Self-administered leaflet
- Where
- Switzerland
- Volunteers
- 102 people
- Sponsor
- University Hospital, Geneva
Colonoscopy, Bowel Cleansing
The Effect of pH Value of Water Consumed During Bowel Preparation Before Colonoscopy on Colon Cleansing
Colonoscopy is a commonly used minimally invasive method for evaluating the lower gastrointestinal tract. The quality of colonoscopy is assessed by factors such as cecal intubation rate and adenoma detection rate, both of which…
- Conditions
- Colonoscopy, Bowel Cleansing, Water Intake, pH
- Trial name
- NCT07669116
- Testing
- Colon preparation for colonoscopy
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Sinan Ömeroğlu, MD
Bowel Preparation
Investigation of PicoPrep Versus HalfLytely for Bowel Preparation for Colonoscopy - Split Dose PicoPrep
Subjects undergoing an elective complete colonoscopy will randomly receive either PicoPrep: 2-sachets for oral solution in two divided doses given a night before (first dose - sachet) and approximately 5 hours prior to procedure…
- Trial name
- NCT01073930
- Testing
- PicoPrep, HalfLytely, bisacodyl
- Where
- 9 sites in United States
- Volunteers
- 608 people
- Sponsor
- Ferring Pharmaceuticals
Colorectal Cancer
Efficacy and Tolerability of Suprep With and Without Simethicone for Routine Colonoscopy for Colorectal Cancer Screening
The purpose of this study is to investigate Suprep bowel preparation, with and without the anti-gas medication simethicone, in terms of efficacy and patient tolerability in the preparation of patients undergoing routine…
- Trial name
- NCT02523911
- Testing
- Simethicone, sodium sulfate/potassium sulfate/magnesium sulfate solution
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- MercyOne Des Moines Medical Center
Colorectal Cancer, Colonoscopy Preparation
The Effect of Nurse Process on Bowel Cleansing
Colonoscopy is still the gold standard method for the diagnosis and treatment of colon cancers. Preparation for colonoscopy is a complex processa (eg.
- Conditions
- Colorectal Cancer, Colonoscopy Preparation, Boston Bowel Preparation Scale, Nursing
- Trial name
- NCT06453655
- Testing
- Nursing Process
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Polyethylene Glycol, Sodium Phosphate
Randomized Controlled Trail of Polyethylene Glycol vs Sodium Phosphate for Colonic Cleansing of Colonoscopy
This study is to compare polyethylene glycol and sodium phosphate for colonic cleansing of colonoscopy.
- Trial name
- NCT03817788
- Testing
- polyethylene glycol, sodium phosphate
- Where
- China
- Volunteers
- 586 people, healthy volunteers welcome
- Sponsor
- Dong Yang
Cleansing Quality of the Colon
Artificial Intelligence and Bowel Cleansing Quality
The main purpose of the study is to assess if a strategy based on a mobile application linked to a neural network is useful for guiding colon cleansing in a more personalized way is better than the usual care defined as regular…
- Trial name
- CALPER3 (NCT05871814)
- Testing
- Colon preparation guided by an artificial intelligence device
- Where
- Spain
- Volunteers
- 774 people
- Sponsor
- University of La Laguna
Colon Cancer
Pharmacodynamic and Clinical Evaluation of Dose and Taste-optimised Low Volume PEG-based Bowel Cleansing Solutions Using the Split-dosing Intake Regimen in Healthy Subjects and in Subjects Undergoing Screening Colonoscopy
A study to assess the pharmacodynamics, safety and tolerability of a PEG-based bowel cleansing solution (MOVIPREP®)
- Trial name
- NCT01714466
- Testing
- NER1006, MOVIPREP
- Where
- 2 sites in Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Norgine
Colonoscopy Preparation
PEG Versus PEG+Bisacodyl Versus Sennosides for Colon Cleansing Before Colonoscopy
Background: Polyethylene glycol (PEG) solution has been proven to be effective for large bowel cleansing prior to colonoscopy in children.
- Trial name
- NCT01531140
- Testing
- polyethylene glycol +Bisacodyl, Polyethylene glycol, Sennosides
- Where
- 2 sites in Poland
- Volunteers
- 240 people
- Sponsor
- Medical University of Warsaw
Need for Bowel Preparation
Efficacy and Safety of Prepopik® in Children for Overall Colon Cleansing in Preparation for Colonoscopy
To study the efficacy and safety of Prepopik® in children aged 9 to 16 years for overall colon cleansing in preparation of colonoscopy
- Trial name
- Prepopik PREA (NCT01928862)
- Testing
- Prepopik® ½ Sachet x 2 (9-12 years), Prepopik® 1 Sachet x 2 (9-12 years), Oral polyethylene glycol (PEG) based preparation (9-12 years)
- Where
- 9 sites in United States
- Volunteers
- 78 people
- Sponsor
- Ferring Pharmaceuticals