Clinical trials: Colon Lesion
Colorectal Cancer, Precancerous Lesion
Study on the Diagnostic Value of Multi-omics Combined Detection for Precancerous Lesions of CRC
Colorectal cancer (CRC) has become one of the most common malignant tumors in the world, and the key to its prevention and control is early detection and treatment.
- Conditions
- Colorectal Cancer, Precancerous Lesion, Inflammatory Bowel Diseases
- Trial name
- NCT05530746
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Neoplasms, Colonic Polyps
Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study
We hypothesize that high definition narrow band imaging (NBI) colonoscopy compared to high definition white light colonoscopy will detect an increased number of nonpolypoid (flat and depressed) colorectal neoplasm.
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Colorectal Cancer
- Trial name
- NBI (NCT01310699)
- Testing
- Olympus Colonoscope CFHQ190AL
- Where
- 3 sites in United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Microscopic Colitis, Colorectal Cancer
Mucosa Adherent Intestinal Microbiome in Microscopic Colitis and Colorectal Cancer
Microscopic colitis (MC) is an inflammatory bowel disease characterized by chronic non-bloody watery diarrhoea and a macroscopically normal colonic mucosa upon endoscopic exploration (colonoscopy).
- Conditions
- Microscopic Colitis, Colorectal Cancer, Colon Adenoma
- Trial name
- CMBACT (NCT06172647)
- Testing
- Colonoscopy
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Mutua de Terrassa
Recurrence
Post-resection Treatment of Large Colon Polyps
Patients who have provided informed consented and are scheduled to undergo endoscopic mucosal resection (EMR) of lesions 15mm and larger will be randomized to STSC (80 W, Effect 5) vs APC (preferred settings) vs No Treatment of…
- Trial name
- SAP (NCT03654209)
- Testing
- Argon Plasma Coagulation, Snare Tip Soft Coagulation
- Where
- 10 sites in United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Indiana University
Serrated Lesion, Adenoma
Serrated Lesions Detection With Endocuff-assisted Colonoscopy
Colorectal cancer (CRC) is a leading cause of morbidity and mortality worldwide, especially in Western countries. CRC is currently considered a preventable disease and screening has been endorsed by several societies, since it…
- Conditions
- Serrated Lesion, Adenoma, Colorectal Cancer
- Trial name
- NCT03856957
- Testing
- Endocuff colonoscopy, control
- Where
- Portugal
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Hospital Beatriz Ângelo
Colorectal Cancer
Prevention and Early Detection Biomarkers of Adenomas and CRC Lesions During CRC Screening
The investigators designed a prospective study to evaluate the predictive ability of detection of mutations in genes involved in carcinogenesis of the colon (eg hMLH1, K-Ras, B-Raf, ccfDNA) in a sample of Greek population…
- Trial name
- NCT02596113
- Where
- Greece
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Evangelismos Hospital
Colonic Lesions
Prospective Image Collection of Colorectal Polyps.
It concerns a study in which we wish to collect images and corresponding histological information (microscopic characteristics) in a prospective manner in various European and non-European centers (multicentric).
- Trial name
- NCT07401264
- Where
- Belgium
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sessile Serrated Lesion, CADe
USAGE OF ARITIFICIAL INTELLIGENCE IN AIDING WITH COLONIC SESSILE SERRATED LESIONS DETECTION AND DIAGNOSIS (AI-SSL)
The aim of this study is to is to evaluate if a real-time Computer Aided Detection (CADe) system can help improve the detection of SSL(sessile serrated lesions) versus a conventional colonoscopy (CC) using white light…
- Trial name
- AI-SSLD (NCT07650344)
- Testing
- usage of CADe system
- Where
- 3 sites in Singapore
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- National Healthcare Group, Singapore
Adenoma
The MORDIS Study Clinical Investigational Plan
To demonstrate the use of WavSTAT4 system during colonoscopy in identifying diminutive colorectal lesions (e.g. hyperplastic polyps) that can be resected and discarded (or even left in-situ) without adverse clinical impact.
- Trial name
- MORDIS (NCT01980134)
- Where
- 6 sites in Czechia, Denmark and 3 more
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- SpectraScience
Sessile Colonic Polyp, Serrated Lesion
Computer-Aided Water Exchange Colonoscopy With and Without Linked-Color Imaging for Detection of Clinically Significant Serrated Lesions
The goal of this clinical trial is to compare the detection rate of clinically significant serrated lesions (CSSL) in participants undergoing water exchange (WE) colonoscopy with artificial intelligence (AI)-based computer-aided…
- Conditions
- Sessile Colonic Polyp, Serrated Lesion, Sessile Serrated Lesion, Colon Adenomas
- Trial name
- NCT07127471
- Testing
- Water exchange with AI-assisted detection, Water exchange with AI-assisted detection and LCI
- Where
- 4 sites in Canada, Italy and 2 more
- Volunteers
- 1,090 people, healthy volunteers welcome
- Sponsor
- Evergreen General Hospital, Taiwan