Clinical trials: Colon Neoplasm
Colorectal Cancer
Computerized and Mailed Reminders in Increasing the Rate of Colorectal Cancer Screening in Adults With an Average Risk for Colorectal Cancer
RATIONALE: Screening may help doctors find colorectal cancer sooner, when it may be easier to treat. Computerized and mailed reminders may help increase the rate of colorectal cancer screening in adults with an average risk for…
- Trial name
- NCT00355004
- Testing
- counseling intervention, fecal occult blood test, screening colonoscopy
- Where
- 3 sites in United States
- Volunteers
- 21,860 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Prostate Cancer, Breast Cancer
Collection of Blood From Patients With Cancer
This study will collect blood from patients with cancer to study the level of cells which decrease the immune response (suppressor cells) before and after chemotherapy.
- Conditions
- Prostate Cancer, Breast Cancer, Colon Cancer, Lung Cancer
- Trial name
- NCT00034216
- Where
- United States
- Volunteers
- 1,750 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer
Effectiveness of Fecal Immunnochemical Test and Colonoscopy Screening in Hong Kong
Colorectal neoplasm in Asia is now increasingly common and is rising in an alarming manner in Hong Kong. Population-based screening for colorectal cancer (CRC) should be implemented.
- Trial name
- NCT03597204
- Testing
- Fecal immunochemical test (FIT), Colonoscopy
- Where
- Hong Kong
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Cancer, Colon Cancer
Online Study of Colorectal Cancer and Prostate Cancer Screening Decision Making
Participants will be recruited from the United States and Australia to take an online survey about colon cancer screening or prostate cancer screening.
- Conditions
- Colorectal Cancer, Colon Cancer, Prostate Cancer
- Trial name
- CARR2 (NCT01558583)
- Testing
- Rating and Ranking Task, Discrete Choice Task, Balance Sheet Task
- Where
- United States
- Volunteers
- 1,831 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection.
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Ann Arbor Stage I Lymphoma, Ann Arbor Stage II Lymphoma
- Trial name
- NCT05334069
- Testing
- Questionnaire Administration, Biospecimen Collection
- Where
- 747 sites in United States
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Lynch Syndrome, Polyposis Syndrome, Hereditary Mixed, 1
PSYLIVED: the Psychological Impacts of Living With an Inherited Colorectal Cancer Predisposition Syndrome
Why? PSYLIVED is a qualitative study that aims to understand the psychological experience of individuals living with inherited colorectal cancer.
- Conditions
- Lynch Syndrome, Polyposis Syndrome, Hereditary Mixed, 1, Polyposis Syndrome, Hereditary Mixed, 2
- Trial name
- PSYLIVED (NCT06447961)
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Colorectal Cancer, Colorectal Neoplasms
Early Onset Colorectal Cancer Detection
Colorectal cancer (CRC) once predominantly affected older individuals, but in recent years has witnessed a progressive increase in incidence among young adults.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenocarcinoma, Colorectal Cancer Stage I
- Trial name
- ENCODE (NCT06342401)
- Testing
- ENCODE
- Where
- 13 sites in United States, Italy and 2 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Cancer Colorectal
Calm for Cancer Patients Receiving Chemotherapy
Chemotherapy is a common strategy used to treat colorectal cancer patients, but is often leads patients and survivors to experience a host of symptoms, of which acute emotional distress is a major concern.
- Trial name
- NCT04345952
- Testing
- Calm Meditation Mobile App
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Artificial Intelligence, Deep Learning
Development and Demonstration of Intelligent Assessment Based on Multi-modal Information Fusion for Tumor Risk and Diagnosis and Treatment
To improve the accuracy of risk prediction, screening and treatment outcome of cancer, we aim to establish a medical database that includes standardized and structured clinical diagnosis and treatment information, image features…
- Conditions
- Artificial Intelligence, Deep Learning, Lung Cancer, Lung; Node
- Trial name
- NCT06653478
- Testing
- No Intervention
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Colonoscopy, Colonic Polyps
Implementation of Optical Diagnosis for Diminutive Polyps Amongst Endoscopists: Training and Long-term Quality Assurance
In this study, Dutch gastroenterologists who are certified for performing colonoscopies on FIT-positive patients in the Dutch population screening program are trained in optical diagnosis with validated methods.
- Trial name
- DISCOUNT2 (NCT02407925)
- Testing
- Feedback
- Where
- 13 sites in Netherlands
- Volunteers
- 3,144 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Colorectal Cancer
Promoting CRC Screening in an Urban Minority Population
The purpose of this study (Healthy Colon Project II) is to evaluate different educational approaches for increasing rates of colorectal cancer (CRC) screening in a hard-to-reach urban minority population with health insurance.
- Trial name
- NCT02392143
- Testing
- Printed Education Material, Academic Detailing, Academic Detailing+Telephone Education
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
Colon Cancer, Breast Cancer
Understanding the Value of Community Vital Signs in Primary Care
Social determinants of health (e.g. the income, education, and environment of patients) may exert greater influence on health outcomes than traditional clinical factors (e.g. lab results, diagnoses, and family history).
- Conditions
- Colon Cancer, Breast Cancer, Cervical Cancer, Prostate Cancer
- Trial name
- NCT02512835
- Testing
- Community vital signs
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Colorectal Cancer
Colorectal Inflammatory Response to a Western-Style Diet
The investigators are involved in a research program to understand how different diets may affect the risk of colorectal polyps and cancer.
- Trial name
- NCT00932308
- Testing
- Western-style diet (WD), Prudent Diet (PD)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Hereditary Cancer Syndrome
Cancer Health Assessments Reaching Many
The CHARM (Cancer Health Assessment Reaching Many) study will assess the utility of clinical exome sequencing and how it affects care in diverse populations.
- Trial name
- CHARM (NCT03426878)
- Testing
- Modified genetic counseling, Traditional genetic counseling
- Where
- 2 sites in United States
- Volunteers
- 967 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Cancer of Colon, Cancer of Rectum
Colorectal Health Research Champions
The purpose of the Colorectal Health Research Champions program is to provide accurate and reliable colorectal health cancer information that they can share within their communities to encourage cancer prevention, screening, and…
- Trial name
- NCT04812743
- Testing
- Colorectal Health Research Champions
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Colorectal Cancer
Reducing Colorectal Cancer Death Through Mailed Outreach Screening
The main study aim is to develop, implement and disseminate a pilot population-based mailed FIT outreach screening program in the Philadelphia VA Medical Center that does not rely on having an office visit, by conducting a…
- Trial name
- NCT02584998
- Testing
- Mailed-FIT, Screening invitation-reminder
- Where
- United States
- Volunteers
- 782 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Colon Inflammation, Iron Malabsorption
Obesity, Iron Regulation and Colorectal Cancer Risk
Obesity is an independent risk factor for colorectal cancer (CRC) although the underlying mechanisms have not been elucidated. Dietary nutrients play a key role in both the prevention and promotion of CRC.
- Conditions
- Colon Inflammation, Iron Malabsorption, Obesity, Diet Modification
- Trial name
- NCT03548948
- Testing
- High heme iron diet, Low iron diet, Plant-based high non-heme iron diet
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Colorectal Cancer
Specimens for Septin 9 Performance
Epigenomics has identified methylated gene regions that are specific for colorectal cancer (CRC). Through Epigenomics' marker discovery and validation process Septin 9 was identified as a particularly robust methylation marker…
- Trial name
- SPR0012 (NCT01329718)
- Testing
- Blood Sample
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Epigenomics, Inc
Colorectal Cancer Stage 0, Colorectal Cancer Stage I
Matrilysin Expression in Different Stages of Colorectal Tumors
Matrix metalloproteinases (MMPs) have been shown to be involved in cancer biology. Significant expression of MMP-7 (matrilysin) in colorectal cancer is mainly associated with metastatic disease even though it is expressed in most…
- Conditions
- Colorectal Cancer Stage 0, Colorectal Cancer Stage I, Colorectal Cancer Stage II, Colorectal Cancer Stage III
- Trial name
- MMP7 (NCT01570452)
- Testing
- colonic or colorectal resection
- Where
- Italy
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Colorectal Cancer
The Clinical Application of 68Ga Labeled ssDNA Aptamer Sgc8 in Healthy Volunteers and Colorectal Patients
The protein tyrosine kinase-7 (PTK7) is overexpressed in various types of human cancers. As a specific imaging agent of PTK7, 68Ga-Sgc8 was investigated in this study to assess its safety, biodistribution and dosimetric…
- Trial name
- NCT03385148
- Testing
- 68Ga-Sgc8
- Where
- 2 sites in China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
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