Clinical trials: Colon Neoplasm
Colon Cancer, Colonic Neoplasms
A Randomized Trial of Cancer Risk and Health Education in Relatives of Colorectal Cancer Patients
Having at least one first-degree relative (FDR) with colon cancer increases an individual's risk of developing the disease. Many relatives of cancer patients are ineligible for genetic testing and, therefore, do not receive…
- Trial name
- NCT00188305
- Testing
- General health counselling and risk information
- Where
- 2 sites in Canada
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Colorectal Cancer Screening, Colon Polyps and Adenomas
Artificial Intelligence (AI) Technology May Help Patients to Understand Bowel Preparation Better Before They go for Colonoscopy.This Study Attempts to Leverage AI Chatbot in Counselling Patients to Improve Bowel Cleanliness, Reduce Anxiety as Well as Increase Procedural Satisfaction
Traditional pre-colonoscopy counselling requires significant time from healthcare workers to explain procedures, limiting efficiency and patient turnover.
- Conditions
- Colorectal Cancer Screening, Colon Polyps and Adenomas, Bowel Preparation Quality, Artificial Intelligence (AI)
- Trial name
- NCT06905782
- Testing
- AI chatbot study arm, Traditional counselling study arm
- Where
- Malaysia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
BRCA1-Related Hereditary Breast and Ovarian Cancer Syndrome, BRCA2-Related Hereditary Breast and Ovarian Cancer Syndrome
A Web-Based Program (Kindred) to Improve the Understanding of Genetic Cancer Risk and Cancer Genetic Testing in African American Families
This clinical trial studies whether a web-based program, Kindred, works to improve the understanding of genetic cancer risk and cancer genetic testing in African American families.
- Conditions
- BRCA1-Related Hereditary Breast and Ovarian Cancer Syndrome, BRCA2-Related Hereditary Breast and Ovarian Cancer Syndrome, Hereditary Neoplastic Syndrome, Lynch Syndrome
- Trial name
- NCT07542405
- Testing
- Discussion, Internet-Based Intervention, Survey Administration
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Michigan Rogel Cancer Center
Colorectal Cancer
Colorectal Cancer Awareness, Research and Education and Screening - Rural Expansion, Access and Capacity for Health
This study is to assess the impact of the CARES-REACH intervention on colorectal cancer screening rates.
- Trial name
- CARES-REACH (NCT04464668)
- Testing
- Provider Tools, Provider surveys
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Colorectal Polyps
Colorectal Polypectomy Upon Insertion And Withdrawal Or Upon Withdrawal Only?
The investigators aim to assess the procedure time and miss rate of polyps when performing polypectomy in the colon on the way up* and down or only on the way down.
- Trial name
- NCT01607827
- Testing
- Polyp removal upon insertion and withdrawal, Polyp removal upon withdrawal only
- Where
- Switzerland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Colorectal Cancer
Use and Decision-making About Colorectal Cancer Screening Among Hispanic Men and Women
During this first year, the researchers have worked toward identifying factors influencing initiation of colorectal cancer screening among Hispanic men and women aged 50 and older and developing an intervention plan using…
- Trial name
- NCT00136227
- Testing
- small media intervention using video, flip chart, and pamphlets and a tailored interactive multimedia intervention
- Where
- United States
- Volunteers
- 521 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Cancer, Colorectal Cancer
Screen to Save 2: Rural Cancer Screening Educational Intervention
The purpose of this study is to help the Dartmouth Cancer Center and the National Cancer Institute understand how to educate people about cancer screening.
- Trial name
- NCT04414306
- Testing
- Online educational video and website module
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Colorectal Cancer, Adenoma
NORCCAP: Norwegian Colorectal Cancer Prevention Trial
The purpose of this study is to see if screening with flexible sigmoidoscopy (a flexible viewing tube) may reduce large bowel cancer and cancer deaths.
- Trial name
- NORCCAP (NCT00119912)
- Testing
- A 1 Intervention arm Flex Sig, A 2 Intervention arm Flex Sig + iFOBT
- Where
- Norway
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Colorectal Cancer
Assessment of Glypican 3 as Apredictive Marker in Colorectal Cancer Patients
Evaluation Of Glypican 3 in serum of colorectal cancer patients . Correlation between Glypican 3 and clinicopathological characteristics of colorectal cancer .
- Trial name
- NCT04728139
- Testing
- glypican 3
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Lynch Syndrome, Li Fraumeni Syndrome
Video Capsule Examination in Patients With Lynch Syndrome
Surveillance for colorectal cancer (CRC) in patients predisposed to develop CRC during their lifetime has been impacted by access to colonoscopy suites and endoscopy specialists in the past couple of years.
- Conditions
- Lynch Syndrome, Li Fraumeni Syndrome, PTEN Hamartoma Syndrome, FAP
- Trial name
- PILLCAM (NCT06712095)
- Testing
- Video capsule investigation
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Colorectal Cancer
Three-port Versus Conventional Laparoscopic Surgery for Colorectal Cancer
This study is designed to evaluate the short-term and long-term results after three-port laparoscopic surgery for colorectal cancer(TLSC) compared with conventional laparoscopic surgery for colorectal cancer(CLSC).
- Trial name
- NCT03426514
- Testing
- Three-port Laparoscopic Surgery, Conventional Laparoscopic Surgery
- Where
- China
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Colo-rectal Cancer
EXercise And Colo-Rectal Cancer Trial
The aim of this study is to assess the feasibility and effectiveness of a home-based walking and strengthening intervention on physiological, biochemical and psychological outcomes in colo-rectal cancer survivors.
- Trial name
- EXACT (NCT02607787)
- Testing
- Exercise, Control
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Breast Cancer, Colon Cancer
Partnership for Healthy Seniors
The Centers for Medicare and Medicaid Services (CMS) has awarded cooperative agreements to 6 sites from across the country (Salt Lake City, UT, Molokai, HI, Houston, TX, Newark, NJ, Detroit, MI, and Baltimore City) to participate…
- Conditions
- Breast Cancer, Colon Cancer, Rectum Cancer, Cervix Cancer
- Trial name
- NCT00379743
- Testing
- Health coordinator (or patient navigator), Educational materials only
- Where
- United States
- Volunteers
- 2,593 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Malignant Female Reproductive System Neoplasm, Malignant Hepatobiliary Neoplasm
Acceptance and Commitment Therapy in Improving Well-Being in Patients With Stage III-IV Cancer and Their Partners
This pilot clinical trial studies how well acceptance and commitment therapy works in improving well-being in patients with stage III-IV cancer and their partners.
- Conditions
- Malignant Female Reproductive System Neoplasm, Malignant Hepatobiliary Neoplasm, Partner, Stage III Breast Cancer
- Trial name
- NCT03112668
- Testing
- Cognitive Behavior Therapy, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Colon Cancer, Colon Rectal Cancer
EndoStyle: Artificial Intelligence Image Transformation Tool for Colonoscopy
The study addresses the limitations of current AI systems in gastrointestinal endoscopy, which are tipically trained with data from a single type of endoscopy processor and have limited expert-annotated images.
- Trial name
- EndoStyle (NCT06553326)
- Testing
- EndoStyle
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Colorectal Cancer
A Model for the Early Diagnosis of Colorectal Cancer by the Detection of 5-hydroxymethylcytosine (5-hmC) in Plasma Cell-free DNA
In this study, the investigators establish a model for the early diagnosis of colorectal cancer based on detection of 5-hydroxymethylcytosine (5-hmC) in training group and validate the effectiveness of the model using a…
- Trial name
- NCT03599947
- Where
- China
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Fudan University
Colorectal Cancer
Guardant Shield Colorectal Cancer Screening
The purpose of this research is to identify individuals overdue for colon cancer screening and send them a reminder to complete their screening, which includes standard of care colonoscopy or stool-based testing.
- Trial name
- NCT07436637
- Testing
- Screening Reminder, Blood Sample Collection
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Miami
Colorectal Cancer, Screening Compliance
WhatsApp Reminder on FIT Compliance
It is estimated that there are about 1.4 million patients with colorectal cancer (CRC) worldwide, with a rising trend in CRC incidence in many Asian Pacific countries.
- Conditions
- Colorectal Cancer, Screening Compliance, Fecal Immunochemical Test
- Trial name
- NCT03209765
- Testing
- WhatsApp reminder
- Where
- Hong Kong
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Tuberculosis, Gastric Cancer
Volatiles in Breath and Headspace Analysis - Diagnostic Markers
Detection of Volatile Organic Compounds (VOC) directly from tissue by headspace analysis (skin, surgery material, other tissue) and exhaled breath is feasible using affordable user-friendly novel nano-chemo sensors that can…
- Conditions
- Tuberculosis, Gastric Cancer, Peptic Ulcer, Atrophic Gastritis
- Trial name
- Volatolome (NCT03228095)
- Testing
- VOC detection in breath and in skin headspace, Breath sampling, Upper endoscopy with biopsies
- Where
- Latvia
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Latvia
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