Clinical trials: Colon Neoplasms
Colorectal Cancer
REINFORCEMENT ANASTOMOSIS WITH Modified Cyanacrylate IN Patients Undergoing to Oncologic Colorectal Surgery With Colorectal Anastomosis
In colorectal surgery about 30% of postoperative mortality is attributed to anastomotic leak, whit an incidence range between 1.8% and 15.9%.
- Trial name
- ANASTOSEAL (NCT03380858)
- Testing
- colectomy
- Where
- Italy
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Naples
Colorectal Disorders, Colorectal Neoplasms
Comparison of the Left-Lateral Horizontal and Supine Positions for Colonoscopy Intervention: A Randomized Controlled Study
Objective: One of the most common technical difficulties during colonoscopy is passing through the fold of the sigmoid colon. Colonoscopy is commonly performed by endoscopists with the patient in the left lateral position.
- Conditions
- Colorectal Disorders, Colorectal Neoplasms, Colorectal Polyp, Colo-rectal Cancer
- Trial name
- NCT07517848
- Testing
- Colonoscopy after bowel cleansing
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Colorectal Cancer
Establishment and Clinical Validation of New Technologies for Accurate Screening of Colorectal Cancer Based on Multi-omics
Background: The current screening techniques for colorectal cancer include colonoscopy, fecal occult blood, and high-risk factor questionnaires.
- Trial name
- NCT04913233
- Where
- 3 sites in China
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colorectal Cancer
Colorectal Cancer Awareness, Research and Education and Screening - Rural Expansion, Access and Capacity for Health
This study is to assess the impact of the CARES-REACH intervention on colorectal cancer screening rates.
- Trial name
- CARES-REACH (NCT04464668)
- Testing
- Provider Tools, Provider surveys
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Colorectal Cancer, Colorectal Adenoma
Circulating Tumor DNA in Patients Summoned for Colonoscopy; - a Liquid Biopsy for Detection, Characterization, Individualized Treatment and Follow-up of Colorectal Cancer
CoLiQ is a clinical study designed to evaluate the clinical usefulness of circulating tumor DNA (ctDNA) markers found in blood, as a liquid biopsy for diagnosis, prognosis and follow-up of colorectal cancer.
- Trial name
- CoLiQ (NCT06307938)
- Testing
- liquid biopsy
- Where
- Norway
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Helse Nord-Trøndelag HF
Colorectal Cancer
Exploratory Analysis on the Impact of Morbidities on Colorectal Cancer Screening Uptake
The primary aim of this project is to examine the association between having a long-term condition (morbidity) and screening uptake for colorectal cancer.
- Trial name
- NCT02503969
- Testing
- Exposure to having a long-term condition.
- Where
- United Kingdom
- Volunteers
- 8,776 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Colon Cancer
Fiber to Reduce Colon Cancer in Alaska Native People
Alaska native people (AN) have the highest recorded incidence and death rate from colon cancer in the world (>90:100,000). We hypothesize that the AN, despite their high consumption of anti-inflammatory and antineoplastic n-3…
- Trial name
- NCT03028831
- Testing
- 70g of fully digestible starch amylopectin corn starch, Resistant starch
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Colorectal Cancer
Assessment of Glypican 3 as Apredictive Marker in Colorectal Cancer Patients
Evaluation Of Glypican 3 in serum of colorectal cancer patients . Correlation between Glypican 3 and clinicopathological characteristics of colorectal cancer .
- Trial name
- NCT04728139
- Testing
- glypican 3
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Colorectal Cancer, Colon Polyps
Prevalence and Topography of Adenomas in 40-49 Year Old Patients With a Family History of Colon Cancer
Conflicting guideline recommendations for screening colonoscopy result due to scant data upon which to develop appropriate recommendations.
- Conditions
- Colorectal Cancer, Colon Polyps, Adenomatous Polyp of Colon
- Trial name
- NCT02289053
- Where
- 6 sites in United States
- Volunteers
- 1,623 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Colorectal Cancer, Inflammation
Reducing Metabolic Dysregulation in Dyads
This study is a 6-month randomized controlled trail of diet modification designed to reduce chronic inflammation and reverse metabolic dysfunction among obese individuals with one or more polyps found at a colonoscopy screening.
- Conditions
- Colorectal Cancer, Inflammation, Nutrition Related Cancer
- Trial name
- REMEDY (NCT06117241)
- Testing
- IMAGINE HEALTHY
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Colorectal Carcinoma
The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Injectable SPN01 in Phase I.
The primary objective of this study is: to evaluate the safety and tolerability of injectable SPN01 in subjects. The secondary objective of this study is: to evaluate the pharmacokinetic characteristics of injectable SPN01 in…
- Trial name
- NCT06710561
- Testing
- SPN01 for Injection
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Beijing SonoPhotoNano Medical Technology Co., Ltd.
Cancer Colon
Genetic Variants of Selected Genes in Colo-Rectal Cancer Patients.
Colorectal cancers (CRC) are the third most common human malignancy, and are also the leading cause of cancer related deaths worldwide.
- Trial name
- NCT02542670
- Testing
- Whole genome sequencing
- Where
- 2 sites in Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sherief Abd-Elsalam
Advanced Colorectal Cancer, Colo-rectal Cancer
Optimal Surveillance Strategy After Positive FIT and Negative Colonoscopy
Individuals with high fecal hemoglobin concentrations detected by fecal immunochemical testing (FIT) but negative findings on high-quality colonoscopy represent a clinically challenging population.
- Conditions
- Advanced Colorectal Cancer, Colo-rectal Cancer, Fecal Immunochemical Test
- Trial name
- NCT07470658
- Testing
- Colonoscopy Surveillance
- Where
- Taiwan
- Volunteers
- 1,274 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Colorectal Cancer
RCT of Automated Telephone Outreach to Improve Colorectal Cancer Screening
This large randomized controlled trial is testing the effectiveness of automated telephone outreach with speech recognition to improve rates of screening for colorectal cancer.
- Trial name
- NCT00792285
- Testing
- Automated Telephone Outreach with Speech Recognition
- Where
- United States
- Volunteers
- 80,000 people, healthy volunteers welcome
- Sponsor
- Harvard Pilgrim Health Care
Colorectum
Prospective Trial of Metformin - Chemoprevention Role
The goal of this clinical research study is to learn if metformin extended release (ER) can prevent colonic adenomas from becoming cancerous. Metformin ER will be compared to a placebo.
- Trial name
- NCT01550900
- Testing
- Metformin ER
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Neoplasms
Message Framing and Colorectal Cancer Screening
The main purpose of this study is to promote colorectal cancer (CRC) screening among individuals who have never been screened, with these individuals being members of a panel who participant in online studies.
- Trial name
- CRC (NCT02483832)
- Testing
- Educational materials
- Where
- United States
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Duke University
Colorectal Cancer, Somatic (Diagnosis)
Mycotoxin Exposure and Dietary Habits in Colorectal Cancer Prevention and Development Among Polish Population
The aim of the study is the determination of the zearalenone and its metabolites (α and β) level in the blood plasma and faeces of patients at increased risk of cancer, in relation to the nutrition data (FFQ) and information on…
- Trial name
- NCT04152265
- Testing
- colonoscopy, questionnaires, demographic data collections
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Warmia and Mazury in Olsztyn
Colon Cancer
Impact of Exercise and Hyperlipidic Meal on Free Circulating DNA in Patients With Metastatic Colonic Cancer and Healthy Subjects
The study of circulating tumoral DNA makes it possible to study, without invasive procedures or pathological studies, the tumoral DNA circulating in the blood of a patient and its various alterations.
- Trial name
- ASRHACOLS (NCT05147545)
- Testing
- Moderate intensity physical effort, Low intensity physical effort, Hyperlipidic meal
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Cancer Screening, Colon Cancer Screening
Evaluating the Shared Decision Making Process Scale in Cancer Screening Decisions
The purpose of this retrospective observational study is to evaluate the performance of the Shared Decision Making Process scale in a sample of patients who have received a decision aid about the decision to screen or not screen…
- Conditions
- Breast Cancer Screening, Colon Cancer Screening, Prostate Cancer Screening
- Trial name
- NCT04601272
- Testing
- Decision aid
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
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