Clinical trials: Colon Rectal Cancer
Colorectal Neoplasms
Diagnostic Performance Assessment of Qualitative Ifobt and Quantitative Ifobt for Advanced Neoplastic
In Argentina, there is vast experience in qualitative iFOBT population screening that is part of the CRC Prevention and Early Detection National Program. The screening's cut-off point is at 50 ng/mL buffer.
- Trial name
- NCT04831632
- Testing
- quantitative and qualitative iFOBTs
- Where
- Argentina
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- CECILIA CURVALE
Colorectal Polyp, Inflammation
Impact of Dietary Intervention on Inflammation and Microbiome Composition Post-Colonoscopy
This study aims to investigate the impact of various healthy diets, specifically a modified plant-based Mediterranean diet, on the gut microbiome and overall well-being post-colonoscopy.
- Conditions
- Colorectal Polyp, Inflammation, Dietary Intervention, Microbiota
- Trial name
- NCT06603519
- Testing
- Modified Plant-Based Mediterranean Diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
High Risk (Above Average) Subjects, Non Compliant Patients for Colo Rectal Cancer [CRC] Screening
Evaluation of C-Scan System in Providing Structural Information and Detection of Polypoid Lesions in High Risk Subjects
The purpose of this study is to establish the efficacy of Check-Cap's C-Scan System in providing structural information on colonic polypoid lesions and masses, as an adjacent tool to Feacal Immunochemical Test [FIT] in high risk…
- Conditions
- High Risk (Above Average) Subjects, Non Compliant Patients for Colo Rectal Cancer [CRC] Screening, Counterindicated Patients for Colonoscopy
- Trial name
- NCT03356002
- Testing
- C-Scan System
- Where
- 7 sites in Israel
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Check-Cap Ltd.
Colorectal Cancer, Precancerous Lesion
Study on the Diagnostic Value of Multi-omics Combined Detection for Precancerous Lesions of CRC
Colorectal cancer (CRC) has become one of the most common malignant tumors in the world, and the key to its prevention and control is early detection and treatment.
- Conditions
- Colorectal Cancer, Precancerous Lesion, Inflammatory Bowel Diseases
- Trial name
- NCT05530746
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Neoplasms, Colonoscopy
AI-assisted Integrated Care to Promote Colonoscopy Uptake
Colorectal cancer (CRC) ranks the second most common cancer and the fourth leading cause of cancer-related deaths in China. Early screening of CRC has been proven to reduce the incidence and mortality, with colonoscopy as the…
- Trial name
- NCT07261059
- Testing
- AI-assisted integrated care
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fudan University
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
EXERCISING TOGETHER for Couples Coping With Cancer
The Exercising Together trial is a single-blind, parallel group, randomized controlled trial comparing 3 arms: Arm 1 (experimental): Exercising Together where couples perform partnered exercise in a supervised, group setting…
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Breast Carcinoma
- Trial name
- NCT03630354
- Testing
- Exercise Intervention (supervised), Exercise Intervention (unsupervised), Informational Intervention
- Where
- United States
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Colorectal Cancer
A Monocentric Study to Investigate a New Low Dose Oral Gut Cleansing Solution
A first study at one centre, with a new oral gut cleansing solution, NRL994, in patients who were going to have a colonoscopy. The study was to find out how well the new "Low Dose Bowel Prep" (LDBP) worked, and whether it was…
- Trial name
- NCT06597903
- Testing
- NRL994
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Norgine
Colon Cancer, Colonic Neoplasms
A Randomized Trial of Cancer Risk and Health Education in Relatives of Colorectal Cancer Patients
Having at least one first-degree relative (FDR) with colon cancer increases an individual's risk of developing the disease. Many relatives of cancer patients are ineligible for genetic testing and, therefore, do not receive…
- Trial name
- NCT00188305
- Testing
- General health counselling and risk information
- Where
- 2 sites in Canada
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Mindfulness, Colon Cancer
Targeting Chronic Stress for Reducing Risk Factors for Colorectal Cancer
Many neighborhoods in Chicago experience daily exposure to stressors including economic inopportunity and violent crime in public spaces.
- Conditions
- Mindfulness, Colon Cancer, Females
- Trial name
- MindCRC (NCT06323421)
- Testing
- Mindfulness
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Colorectal Cancer, Stomach Disease
Screening for Stomach Diseases and Colorectal Neoplasms With the Fecal Testing
1. The abundant results from this trial will be helpful for assessing the feasibility of increasing stool sampling and shortening screening interval in population setting for lower and upper gastrointestinal tract lesions, their…
- Trial name
- NCT01741363
- Testing
- FIT(Eiken OC-Sensor) Two-day sampling, FIT(Eiken OC-Sensor) One-year interval, FIT(Eiken OC-Sensor) One-day sampling
- Where
- Taiwan
- Volunteers
- 99,314 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Colorectal Cancer, Coping, Cognitive
The Effect of Mandala Art Therapy, Psychological Resilience, Coping With Cancer, Colorectal Cancer Surgery
The aim of this study is to evaluate the effects of mandala art therapy on psychological resilience and coping with cancer in patients undergoing colorectal cancer surgery.
- Conditions
- Colorectal Cancer, Coping, Cognitive, Psychological Well-Being
- Trial name
- NCT07535021
- Testing
- Mandala art therapy, rutine service operation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Colorectal Cancer
COlorectal BReath Analysis (COBRA2)
Colorectal cancer (CRC) is the second most common cause of cancer death in the United Kingdom, with approximately 17,000 deaths per year.
- Trial name
- NCT05844514
- Testing
- Breath test
- Where
- 5 sites in United Kingdom
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Brest Cancer, Lung Cancer (NSCLC)
The CCANED-CIPHER Study: Early Cancer Detection and Treatment Response Monitoring Using AI-Based Platelet and Immune Cell Transcriptomic Profiling
The purpose of the CCANED-CIPHER study is to develop and validate an AI-based blood test for early cancer detection and to monitor treatment effectiveness in cancer patients.
- Conditions
- Brest Cancer, Lung Cancer (NSCLC), Pancreatic Cancer, Adult, Prostate Cancers
- Trial name
- CCANED-CIPHER (NCT06717295)
- Testing
- DiNanoQ: A multi-cancer early detection (MCED) blood test, DiNanoTrack: Therapeutic Response Monitoring Blood Test
- Where
- 4 sites in Argentina, Nigeria and 1 more
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Javier Toledo
Colorectal Cancer, Sedentary Lifestyle
Views on Cancer Prevention and Daily Lifestyle
This study is to assess how a theoretically guided mHealth communication informed by evidence of thoughts and affect about colorectal cancer can enhance how an existing mHealth (cell/mobile based text messaging health promotion)…
- Trial name
- NCT03575117
- Testing
- Common-Sense Model (CSM) Be Well, ACS usual messages, NCI HealthyYouTXT--Get Active (HYT--GA)
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of California, Merced
Colorectal Cancer, Prevention
A Cross-sectional Partnership to Improve Prevention and Health Equity Among African Americans
African Americans face racial disparities in colorectal cancer (CRC), with lower screening rates and higher incidence and mortality rates.
- Trial name
- NCT05903885
- Testing
- On-site Fecal Immunochemical Test (FIT) Kit Distribution, On-site With Social Media Advertising Fecal Immunochemical Test (FIT) Kit Distribution
- Where
- 2 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Colorectal Cancer
Diet Modulation of Bacterial Sulfur and Bile Acid Metabolism and Colon Cancer Risk
Determine in the context of a controlled crossover diet-intervention trial the role of taurocholic acid metabolism by gut bacteria in African American subjects at elevated risk for colorectal cancer (CRC).
- Trial name
- NCT03550885
- Testing
- High taurine and saturated fat diet, Low in taurine and saturated fat diet
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Colorectal Cancer, Colorectal Polyps
Does Inspection During Insertion Improve Adenoma Yields During Colonoscopy?
Colonoscopy is not a perfect test. It misses a substantial number of neoplastic lesions and has some risk of missing cancer. Nearly all work on detection during colonoscopy has focused on the withdrawal phase of the examination.
- Trial name
- NCT01035775
- Testing
- Inspection during insertion, Inspection during withdrawal
- Where
- 2 sites in United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colon Polyp, Colon Adenoma
Impact of Screen Size on Colorectal Adenoma Detection
The purpose of this study is to assess whether the use of large screen during colonoscopy will increase adenoma detection rate.
- Conditions
- Colon Polyp, Colon Adenoma, Colorectal Neoplasms
- Trial name
- NCT04749303
- Testing
- Large Screen
- Where
- Hong Kong
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal (Colon or Rectal) Cancer
Promoting Equity for Cancer Screening and Follow-up
This is a randomized trial to assess the efficacy of reminder mechanisms on colorectal cancer (CRC) screening uptake among a cohort of patients who were previously mailed a multitarget stool DNA (mt-sDNA) test and did not…
- Trial name
- NCT04831827
- Testing
- IVR Reminder, Phone call from research team, EHR Portal message
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colorectal Carcinoma
Smart Symptom Tracking ALEX Application for Tracking and Monitoring Gastrointestinal Health, Smart Horizons Pilot Trial
This clinical trial compares the impact of the Smart Symptom Tracking ALEX application (app) to standard symptom-tracking practices in tracking and monitoring gastrointestinal (GI) symptoms in young adults.
- Trial name
- NCT07618273
- Testing
- Artificial Intelligence-based Intervention, Best Practice, Communication Intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic