Clinical trials: Colonic Diverticula, active
Colorectal Cancer, Diverticulitis, Colonic
Colorectal Omics and OfCS Proteoglycans
This observational study aims to test proteomics, metabolomics and proteoglycans as predictors of postoperative complications after colorectal surgery and as biomarkers of colorectal cancer.
- Conditions
- Colorectal Cancer, Diverticulitis, Colonic, Inflammatory Bowel Diseases, Stoma Colostomy
- Trial name
- COCO (NCT06287671)
- Testing
- Colorectal resection or stoma closure
- Where
- 2 sites in Denmark
- Volunteers
- 1,000 people
- Sponsor
- Claus Anders Bertelsen, PhD, MD
Diverticulitis, Colonic
Effectiveness and Safety of Outpatient Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics
The objective of this clinical trial to evaluate the effectiveness and safety of outpatient treatment without antibiotics compared to outpatient treatment with antibiotics in patients with acute uncomplicated diverticulitis.
- Trial name
- ADIANA (NCT06517264)
- Testing
- Antibiotic, Non antibiotic
- Where
- Spain
- Volunteers
- 282 people
- Sponsor
- Monica Mengual Ballester
Diverticulitis Colon, Quality of Life
Quality of Life and Surgery in Diverticular Disease
Diverticular disease is one of the most common diseases of the gastrointestinal tract in industrial countries. Prevalence and admission rate due to diverticular disease increases.
- Conditions
- Diverticulitis Colon, Quality of Life, Diverticular Disease of Left Side of Colon
- Trial name
- NCT05393609
- Testing
- Sigmoidectomy, Conservative
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Colorectal Cancer, Colorectal Anastomosis
Single-Stapled Technique for Colorectal Anastomosis
The goal of this observational multicenter study is to evaluate the safety and feasibility of a single-stapled technique (SST) for colorectal anastomosis and to explore whether this technique is associated with a reduced rate of…
- Conditions
- Colorectal Cancer, Colorectal Anastomosis, Anastomotic Leakage, Diverticular Disease of Left Side of Colon
- Trial name
- SST (NCT07417358)
- Testing
- Single-stapled colorectal anastomosis, Double-stapled colorectal anastomosis
- Where
- 5 sites in Sweden
- Volunteers
- 500 people
- Sponsor
- Umeå University
Colo-rectal Cancer, Colo-rectal Surgery
Post Operative Hospital at Home After Colorectal Surgery
The goal of this feasibility study is to investigate whether a virtual Hospital at Home is safe and possible for patients undergoing planned minimally invasive colorectal surgery.
- Conditions
- Colo-rectal Cancer, Colo-rectal Surgery, Colocolic and Ileocolic Anastomosis, Colon and/or Rectal Resection With Anastomosis for Cancer
- Trial name
- POPHaH (NCT07113717)
- Testing
- virtual Hospital at Home
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Nordsjaellands Hospital
Diverticulitis, Surgical Site Infection
Surgical Site Infection Outcomes in Natural Orifice Intracorporeal Anastomosis and Extraction (NICE) Procedure - The NICE Trial
The goal of this observational study is to learn if a new surgical technique, called the NICE procedure, is as safe as standard methods for treating benign left-sided colon and rectal diseases in adults.
- Conditions
- Diverticulitis, Surgical Site Infection, Surgical Site Infections, Colorectal Surgery
- Trial name
- NCT06957236
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- The Methodist Hospital Research Institute
Diverticular Disease of Colon
Molecular and Microbiota Signatures Underlying Colonic Diverticular Disease
The pathogenesis of diverticular disease is likely multifactorial in origin. This project aims to study the involvement of environmental factors in the pathophysiology of diverticular disease, the underlying molecular mechanisms…
- Trial name
- GR-Barbaro (NCT06764550)
- Testing
- This is an observational study, participants are not assigned an intervention as part of the study.
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Diverticular Disease of Colon, Acute Diverticulitis
Analysis of the Role of the Microbiota in Diverticular Disease
A single-center, prospective observational cohort study conducted at the University Hospital of Navarra. The primary objective is to expand knowledge of diverticular disease and its pathological variants, as well as the influence…
- Conditions
- Diverticular Disease of Colon, Acute Diverticulitis, Gut Microbiota
- Trial name
- NCT07681505
- Where
- Spain
- Volunteers
- 285 people
- Sponsor
- Hospital of Navarra
Colonic Diverticulitis, Colorectal Cancer
The Diverticulitis Study
Acute colonic diverticulitis is when a part of the colon gets swollen and inflamed. The diagnosis is based on a CT scan, which can show thickening of the colonic walls and infiltration of the diverticula.
- Conditions
- Colonic Diverticulitis, Colorectal Cancer, Acute Diverticulitis
- Trial name
- NCT06023004
- Where
- 5 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Diverticular Disease of Colon
Percutaneous Drainage Versus Antibiotic Therapy for Acute Diverticulitis With Abscess.
the management of diverticular abscesses is guided by consensus-based recommendations from the WSES guidelines, the American College of Physicians, and the American Gastroenterological Association, all of which acknowledge the…
- Trial name
- NCT07352605
- Testing
- Arm 1 (Control Arm) - Percutaneous drainage plus antibiotics: Image-guided (CT or ultrasound) percutaneous drainage performed within 48 hours of randomization with intravenous bro, Arm 2 (Experimental Arm) - Antibiotics alone: Intravenous broad-spectrum antibiotics: piperacillin-tazobactam 4 g/0.5 g q6h (dosage to be adjusted based on renal function) according to the recent lite
- Volunteers
- 50 people
- Sponsor
- Azienda Sanitaria di Firenze
Zenker Diverticulum, Polyp of Colon
Advanced Endo-therapeutic Procedure : Registry-based Observational Study
Advanced therapeutic endoscopy procedures are of increasing importance to provide minimal invasive treatment for GI diseases. The Centre Hospitalier de l'Université de Montréal as tertiary university center is dedicated to…
- Conditions
- Zenker Diverticulum, Polyp of Colon, Colo-rectal Cancer
- Trial name
- AE Registry (NCT04117100)
- Testing
- Polypectomy or myotomy
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Diverticulum, Colon, Sigmoid
LASER Trial. LAparoscopic Elective Sigmoid Resection Following divERticulitis - a Multicenter, Prospective, Randomized Clinical Trial
The purpose of this study is to find out whether elective sigmoid resection will improve quality of life compared to conservative treatment with lifestyle guidance and fiber supplement in patients with a recurrent or complicated…
- Trial name
- LASER (NCT02174926)
- Testing
- Elective laparoscopic sigmoid resection, Conservative treatment
- Where
- 11 sites in Finland
- Volunteers
- 133 people
- Sponsor
- Helsinki University Central Hospital