Clinical trials: Colonic Neoplasm
Cancer
Clinical Study of Pan-cancer DNA Methylation Test in Plasma
We intend to establish an efficient method for plasma cfDNA extraction and Bisulfite transformation to facilitate the detection of DNA methylation status using multiplex fluorescence PCR.
- Trial name
- NCT05685524
- Testing
- DNA methylation test
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Wuhan Ammunition Life-tech Co., Ltd
Colorectal Cancer
The FLU-FOBT Program in Primary Care Settings Where Disparities Persist
The investigators overall goals are to adapt, implement, evaluate, and disseminate the FLU-FOBT Program as an integrated nurse-run, primary care-based intervention that can reduce colorectal cancer screening disparities in…
- Trial name
- NCT01211379
- Testing
- FLU-FOBT Program
- Where
- United States
- Volunteers
- 1,372 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Colorectal Cancer
Low-Literacy Physician-Patient Intervention Promoting Colorectal Cancer Screening
The purpose of this study is to evaluate the effectiveness of a low literacy, physician and patient-directed intervention to promote colorectal cancer (CRC) screening among the medically underserved.
- Trial name
- NCT01103479
- Testing
- Physician Intervention, Physician and Patient Intervention
- Where
- 2 sites in United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Colorectal Cancer, Colorectal Adenoma
Accuracy of Real Time Characterization in Artificial Intelligence-assisted Colonoscopy
The goal of this substudy is to investigate the accuracy of a computer-aided polyp characterization (CADx) system. The main question[s] it aims to answer are: How high is the specificity of the AI system when characterizing…
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Colorectal Neoplasms
- Trial name
- NCT05754229
- Testing
- AI-assisted colonoscopy
- Where
- 4 sites in Denmark
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- Ismail Gögenur
Colorectal Cancer
Virtual Reality During Colonoscopy Procedures
Colorectal cancer (CRC) in the United States (US) is the fourth leading cause of cancer- related deaths. In Puerto Rico (PR), the incidence and mortality rate of CRC is higher (41% and 14%) in comparison to the mainland US (38%…
- Trial name
- VR (NCT06236386)
- Testing
- VR Experience
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Ventral Hernias, Cytoreductive Surgery
Ventral Hernias Following Cytoreductive Surgery : Incidence, Risk Factors and Surgical Management.
Cytoreductive surgery (CRS), with or without hyperthermic intraperitoneal chemotherapy (HIPEC), is currently the standard treatment for advanced peritoneal tumors, including pseudomyxoma peritonei (PMP), colorectal, and ovarian…
- Trial name
- NCT07451483
- Where
- Belgium
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Colo-rectal Cancer
Assessing Repeat Fit Testing for CRC
This study will randomly assign 220 men and women to either a social media intervention or a standard reminder system to have a repeat screening test for colo-rectal cancer.
- Trial name
- ARFT (NCT03248661)
- Testing
- Now I'm Telling You
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Richard Crosby
Colorectal Cancer (CRC)
Raising Awareness of Colorectal Screening in American Indian Communities
This study focuses exclusively on American Indian individuals within their communities to enhance health equity and address a critical tribal health priority.
- Trial name
- AIC-DC (NCT07515729)
- Testing
- Navigator-led intervention
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Cancer, Lung, Cancer, Breast
Early Detection of Five Common Cancers Using the ctDNA Analysing Test
This is a multi-centre, prospective cohort study, aiming to evaluate a blood test in early detection of the four common cancers, based on the investigation of the circulating tumour DNA (ctDNA).
- Conditions
- Cancer, Lung, Cancer, Breast, Cancer Liver, Cancer, Colorectal
- Trial name
- K-DETEK (NCT05227261)
- Where
- Vietnam
- Volunteers
- 9,057 people, healthy volunteers welcome
- Sponsor
- Gene Solutions
Breast Cancer, Lung Cancer
Predicting Cancer Risk With Digital and Molecular Markers
The goal of this study is to identify new markers to predict the risk of developing cancer, primarily breast cancer. For this purpose, researchers will compare data obtained from cancer patients and healthy individuals.
- Conditions
- Breast Cancer, Lung Cancer, Colorectal Cancer, Gynecologic Cancer
- Trial name
- PräDigt (NCT06962670)
- Testing
- Biomaterial collection, BayPass mobile application
- Where
- Germany
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Colo-rectal Cancer
Blood Collection Sub-Study for CRC Screening in Individuals 45-49 at Average Risk for CRC.
The primary objective of this sub-study, 2018-10B, is to collect blood specimens to assess new biomarkers for the detection of Colorectal Cancer (CRC).
- Trial name
- NCT03741166
- Testing
- Blood Sample Collection
- Where
- 37 sites in United States
- Volunteers
- 871 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Age-Related Macular Degeneration, Allergies
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and…
- Conditions
- Age-Related Macular Degeneration, Allergies, Alpha-Gal Syndrome, Alzheimer Disease
- Trial name
- NCT05635266
- Testing
- Specimen sample
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Colon Disease, Colonic Neoplasms
3-day vs. 1-day Low Residue Diet Influence in Colonoscopy Preparation and Patient Tolerability
Colonoscopy is one of the most common methods for the diagnosis and treatment of lower gastrointestinal tract diseases and provides a unique opportunity to identify early neoplastic lesions.
- Trial name
- NCT02955901
- Testing
- 3 day low residue diet prior to the colonoscopy, 1 day low residue diet prior to the colonoscopy
- Where
- Portugal
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- Portuguese Oncology Institute, Coimbra
Advanced Cancers
End of Life Treatment Preferences of Latino Medicare Beneficiaries With Cancer
Objectives: The primary objective of the research project is to investigate how declining health status influences the end-of-life (EOL) treatment preferences in Latino Medicare beneficiaries with cancer and to examine if and how…
- Trial name
- NCT01389830
- Testing
- Telephone Survey
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Cancer
Performance Evaluation of the Micromedic CD24 in Vitro Diagnostic Assay
This study is aimed to evaluate the performance of the Micromedic CD24 assay in identifying colorectal adenoma using Western blot and ELISA assays.
- Trial name
- NCT01214512
- Testing
- blood-sample based diagnostic assay
- Where
- 2 sites in Israel
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Colorectal Neoplasms
Chromoendoscopy or Narrow Band Imaging (NBI) for Improving Adenoma Detection in Colonoscopy
Narrow band imaging or electronic chromoendoscopy might provide similar adenoma detection capabilities while limiting time spent when compared to conventional chromoendoscopy method.
- Trial name
- NCT04192929
- Testing
- Narrow band imaging, Chromoendoscopy, High definition white light endoscopy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Colonic Neoplasms
Imaging Colo-rectal Cancer Using a Two Step Antibody Technique in Nuclear Imaging
The purpose of this study is to test the safety of the peptide and antibody and at the same time evaluate the tumor imaging of a two step antibody technique in nuclear imaging.
- Trial name
- NCT00185081
- Testing
- Indium labeled IMP-205xm734
- Where
- Netherlands
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Colorectal Cancer
Colorectal Cancer Detected by 1H-NMR Spectroscopy
The hypothesis of the present study is that metabolic phenotyping of blood plasma allows to (i) discriminate between colorectal cancer patients and control subjects and (ii) identify new biomarkers for colorectal cancer.
- Trial name
- BIOCOR (NCT02364154)
- Testing
- Control group-Blood sampling, Blood sampling
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Colorectal Cancer Screening
Evaluating the Efficacy of the eNav Toolkit to Improve Colorectal Cancer Screening
The purpose of this research study is to evaluate the efficacy of a digital navigation tool, called the eNav to improve colorectal cancer screening uptake among patients treated at federally qualified health centers (FQHC)s.
- Trial name
- NCT06184594
- Testing
- eNav, Standard of Care
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Colorectal Cancer
Increasing Colorectal Cancer Screening in African Americans
RATIONALE: Screening may help doctors find colorectal cancer sooner, when it may be easier to treat. Finding out what affects a patient's decision to undergo screening tests may help increase the number of patients who undergo…
- Trial name
- NCT00893295
- Testing
- informational intervention, medical chart review, screening questionnaire administration
- Where
- United States
- Volunteers
- 896 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
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