Clinical trials: Colonic Neoplasm
Inflammatory Bowel Disease, Uterine Cervical Dysplasia
Immune Response to the Human Papillomavirus Vaccine in Young Women With Inflammatory Bowel Disease
The Gardasil vaccine, a vaccine targeted towards the human papillomavirus (HPV), has been shown to prevent the transmission of several strains of HPV in young women.
- Trial name
- NCT01034358
- Testing
- Human Papillomavirus Vaccine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Metastatic Colorectal Cancer
Positron Emission Tomography - Computed Tomography (PET-CT) Cetuximab Project
Molecular imaging with positron emission tomography (PET) using [18F] fluorodeoxyglucose (FDG) has been suggested as an early, sensitive marker of tumour response to anticancer drugs by monitoring the changes in glucose…
- Trial name
- NCT00828620
- Testing
- Imaging study
- Where
- 6 sites in Belgium
- Volunteers
- 21 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lynch Syndrome
Multi-Organ Screening Recommendations in Patients With Lynch Syndrome
The purpose of this study is to examine how people with a family history of colon cancer and other related cancers respond to recommendations for cancer screening after genetic counseling.
- Trial name
- NCT00582296
- Testing
- questionnaires, telephone interview, optional blood drawn, questionnaires, telephone interview and optional blood drawn
- Where
- 8 sites in United States
- Volunteers
- 1,530 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Colorectal Cancer, Peripheral Neuropathy
Rood's Approach and Oxaliplatin-induced Peripheral Neuropathy in Colorectal Cancer Patients
Oxaliplatin-induced chronic peripheral neuropathy is of major concern to oncologists and patients as it has been shown to affect patients' health-related quality of life.
- Trial name
- NCT05882396
- Testing
- Rood's approach, Traditional physical therapy program
- Volunteers
- 60 people
- Sponsor
- Cairo University
Colorectal Cancer
Stool DNA to Improve Colorectal Cancer Screening Among Alaska Native People
Only 59% of Alaska Native people have been adequately screened for colorectal cancer (CRC) despite having the highest reported incidence of CRC in the world.
- Trial name
- NCT04336397
- Testing
- Multi-target stool DNA test, Colonoscopy
- Where
- United States
- Volunteers
- 2,029 people, healthy volunteers welcome
- Sponsor
- Alaska Native Tribal Health Consortium
Colorectal Cancer
A Study of Xeloda (Capecitabine) in Patients With Advanced and/or Metastatic Colorectal Cancer
This study will assess the efficacy and safety of continuous oral Xeloda administration in combination with intravenous irinotecan as a first-line treatment in patients with advanced and/or metastatic colorectal cancer.
- Trial name
- NCT00048126
- Testing
- Irinotecan, capecitabine [Xeloda]
- Where
- 10 sites in United States
- Volunteers
- 57 people
- Sponsor
- Hoffmann-La Roche
Fear of Cancer Recurrence
The Effect of Metacognition-based, Manualized Intervention on Fear of Cancer Recurrence
The primary aim of this study is to assess the effect of ConquerFear, a metacognition-based manualized intervention on fear of cancer recurrence, using the randomized controlled trial approach, among Chinese patients newly…
- Trial name
- NCT04568226
- Testing
- ConquerFear Intervention, Active control: Basic Cancer Care
- Where
- 6 sites in Hong Kong
- Volunteers
- 177 people
- Sponsor
- The University of Hong Kong
Metastatic Colorectal Cancer, BRAF V600 Mutation
A Study on Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer (mCRC)
Previous studies have shown that BRAFV600E mutant mCRC patients have a shorter survival time than BRAF wild type mCRC patients. For Chinese patients, however, it remains unclear about the BRAF gene mutation rate, diagnosis…
- Trial name
- NCT06749015
- Testing
- Non interventional study
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University
Colorectal Cancer
FOcUs on Colorectal CAncer oUtcomes: Long-Term Study
Colorectal cancer (CRC) affects men and women of all racial and ethnic groups and accounts for more than 600,000 deaths per year, globally.
- Trial name
- Foucault (NCT03965325)
- Testing
- Use of a standardized set to collect clinical and patient-centered data, to assess the trend of the Global Health Status overtime in colorectal cancer patients
- Where
- France
- Volunteers
- 133 people
- Sponsor
- IHU Strasbourg
Colorectal Cancer, Cholangiocarcinoma
A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma
This study is being done to answer the following question: Is the combination of the Medtronic pump and the Codman catheter device a safe alternative to the C3000 Codman pump for delivering chemotherapy directly into the liver of…
- Trial name
- NCT04668976
- Testing
- Medtronic pump and Codman catheter, Floxuridine (FUDR), Gemcitabine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Benaroya Research Institute
Colorectal Cancer, Fatigue
UNTIRE: Cancer-related Fatigue With Digital Treatment
This research is being done to find out if using a smartphone app as digital treatment to reduce Cancer Related Fatigue is feasible and easy to use.
- Trial name
- NCT05584540
- Testing
- UNTIRE App
- Where
- United States
- Sponsor
- Dana-Farber Cancer Institute
Male Breast Cancer, Stage IV Breast Cancer
Cediranib Maleate and Whole Brain Radiation Therapy in Patients With Brain Metastases From Non-Small Cell Lung Cancer
This phase I trial is studying the side effects and best dose of cediranib maleate when given together with whole brain radiation therapy in treating patients with brain metastases from non-small cell lung cancer.
- Conditions
- Male Breast Cancer, Stage IV Breast Cancer, Stage IV Melanoma, Stage IV Non-small Cell Lung Cancer
- Trial name
- NCT00937482
- Testing
- cediranib maleate, whole-brain radiation therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- National Cancer Institute (NCI)
Low Anterior Resection Syndrome, Rectal Cancer
The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection Syndrome After Rectal Cancer Surgery (TraLARS)
The preservation surgery of the anal sphincter muscle has become the standard procedure in the treatment of rectal cancer and, thanks to advancements in surgical techniques, can now be performed for tumors located closer to the…
- Conditions
- Low Anterior Resection Syndrome, Rectal Cancer, Insomnia, Sleep Disorder
- Trial name
- TraLARS (NCT06222255)
- Testing
- Transanal Irrigation (TAI)
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Seoul National University Hospital
Colonic Cancer, Rectal Cancer
Chinese Colorectal Cancer Database
1. To establish the Chinese people's own clinical data database of colorectal cancer, reflecting the law and characteristics of colorectal cancer patients in China. 2.
- Conditions
- Colonic Cancer, Rectal Cancer, Prospective Studies
- Trial name
- CCCD (NCT05434026)
- Where
- China
- Volunteers
- 200,000 people
- Sponsor
- Beijing Friendship Hospital
Colorectal (Colon or Rectal) Cancer, Leak, Anastomotic
Predictive Model For Anastomotic Leakage After Colorectal Cancer Surgery
This pilot study aimed to develop a simplified early postoperative model for AL risk stratification using readily available clinical and laboratory variables.
- Conditions
- Colorectal (Colon or Rectal) Cancer, Leak, Anastomotic, Surgery Complications
- Trial name
- Doesn't exist (NCT07709923)
- Where
- Italy
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Colorectal Cancer
Risk Stratification to Promote Effective Shared Decision-Making for Colorectal Cancer Screening
Shared decision-making (SDM) has been advocated as a strategy for increasing colorectal cancer (CRC) screening rates. Our studies to date suggest that while the use of a novel computer-based decision aid facilitates several…
- Trial name
- NCT01596582
- Testing
- Risk Assessment
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Anemia, Colorectal Neoplasm
IVICA: Intravenous Iron in Colorectal Cancer Associated Anaemia
116 eligible patients with confirmed non-metastatic colorectal adenocarcinoma and anemia will be randomized to receive either oral ferrous sulphate (control) or intravenous ferric carboxymaltose (intervention).
- Trial name
- IVICA (NCT01701310)
- Testing
- Ferric carboxymaltose, Ferrous Sulphate
- Where
- 8 sites in United Kingdom
- Volunteers
- 116 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Colorectal Cancer, Colorectal Adenoma
Volatile Markers in Digestive Cancer
The study is aimed to determine the potential of volatile marker testing for identification of gastrointestinal cancers (in particular - colorectal and gastric cancers), the related precancerous lesions in the stomach and colon.
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Gastric Cancer, Peptic Ulcer Disease
- Trial name
- VOLGACORE (NCT02332213)
- Testing
- Breath sampling for volatile marker detection, Upper endoscopy with biopsies, Colonoscopy with biopsies or lesion removal when required
- Where
- 2 sites in Latvia, Lithuania
- Volunteers
- 2,022 people, healthy volunteers welcome
- Sponsor
- University of Latvia
Stage IV Colorectal Cancer
Exercise Program During Chemotherapy in Metastatic Colorectal Cancer
This pilot clinical trial studies how well aerobic exercise works in improving quality of life and health-related outcomes in patients with stage IV colorectal cancer undergoing chemotherapy.
- Trial name
- NCT03111823
- Testing
- Exercise Intervention, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- University of Southern California
Breast Cancer, Colon Cancer
EXoPERT EMERALD Clinical Study
The purpose of this study is to establish a multi-center clinical repository of blood samples to support the development and evaluation of an artificial intelligence-based in vitro diagnostic software.
- Conditions
- Breast Cancer, Colon Cancer, Pancreatic Cancer, Ovarian Cancer
- Trial name
- NCT07186296
- Testing
- EXoPred
- Where
- 9 sites in United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- EXoPERT
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