Clinical trials: Colonic Neoplasms
Colonic Neoplasms, Colorectal Neoplasms
Performance and Evaluation for CT Colonography Screening
Colorectal cancer (CRC) is an important United Kingdom healthcare issue affecting 1 in 20 individuals, half of whom will die from the disease.
- Trial name
- PERFECTS (NCT02892721)
- Testing
- Training with feedback
- Where
- United Kingdom
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Colorectal Neoplasms, Colorectal Cancer
A Study Comparing Standard and AI-Assisted Colonoscopies for Detecting and Characterizing Colorectal Lesions in Adults Aged 50-74 Undergoing Cancer Screening
The goal of this clinical trial is to determine whether using artificial intelligence (AI) can improve the detection and characterization of abnormal growths (polyps) during colonoscopy in adults aged 50 to 74 years who are…
- Conditions
- Colorectal Neoplasms, Colorectal Cancer, Adenoma Colon Polyp
- Trial name
- NCT07125300
- Testing
- Artificial Intelligence-Assisted Colonoscopy
- Where
- Spain
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Javier Santos Fernández
Colorectal Cancer
Correlation Between Blood Group ,Rh and Obesity With Colorectal Carcinoma
Aim of study: is there possibility of relationship between ABO blood group, Rh \& obesity with CRC, that is what we tried to show in this study .
- Trial name
- NCT05520385
- Testing
- blood group and Rh
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Al-Kindy Teaching Hospital
Colorectal Cancer, Colorectal Neoplasms
Effect of Patient Portal Messaging Before Mailing Fecal Immunochemical Testing Kit on Colorectal Cancer Screening Rates
Behavioral economics principles have increasingly been shown to improve health outcomes in the United States. They offer the ability to implement simple, low-cost and effective interventions to address key health issues without…
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Cancer Screening
- Trial name
- NCT05115916
- Testing
- MyChart Priming Message
- Where
- United States
- Volunteers
- 3,880 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Colorectal Cancer
Scaling CRC Screening Through Outreach, Referral, and Engagement (SCORE)
This study will test the effectiveness of mailing fecal immunochemical tests (FITs) in increasing colorectal cancer (CRC) screening rates in U.S. adults ages 45-75.
- Trial name
- SCORE (NCT04406714)
- Testing
- Trial Mailed FIT Intervention - Age Group 50-75, Sub-Study Mailed FIT Intervention Enhanced Envelope - Age Group 45-49, Sub-Study Mailed FIT Active Comparator Plain Envelope - Age Group 45-49
- Where
- 2 sites in United States
- Volunteers
- 4,318 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Colon Cancer
Screening and Risk Factors of Colon Neoplasia
The investigators propose a screening population-based study to systematically evaluate the accuracy and clinical relevance of sDNA testing as a potential alternative to colonoscopy screening.
- Trial name
- NCT01647776
- Testing
- Stool DNA Test, biopsies of rectal and colon mucosa, Questionnaires
- Where
- United States
- Volunteers
- 3,315 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Colo-rectal Cancer
Evaluation of the Natera Colorectal Cancer Screening Test in an Average Risk Population (FIND-CRC)
The FIND-CRC study is a prospective collection of samples and data from participants who are at average risk of developing colorectal cancer (CRC).
- Trial name
- FIND-CRC (NCT07046585)
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
Colorectal Cancer (MSI-H), Molecular Residual Disease
Research on Colorectal Cancer Recurrence Monitoring and Individualized Treatment Based on MRD
This study aims to evaluate whether plasma molecular residual disease (MRD), assessed using circulating tumor DNA (ctDNA), can help optimize the duration of immunotherapy in patients with metastatic microsatellite…
- Trial name
- NCT07775950
- Testing
- Discontinue NA Treatment, Continued Immunotherapy, Observation
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Artificial Intelligence, Enteroscope
A Clinical Trial of the Effectiveness and Safety of Software Assisting Diagnose the Intestinal Polyp Digestive Endoscopy by Analysis of Colonoscopy Medical Images From Electronic Digestive Endoscopy Equipment
A clinical trial of the effectiveness and safety of intestinal polyp digestive endoscopy-assisted diagnosis software used in the analysis of colonoscopy medical images generated by electronic digestive endoscopy equipment.
- Conditions
- Artificial Intelligence, Enteroscope, Intestinal Polyposis, Adenomatous
- Trial name
- NCT05687318
- Testing
- DeFrame
- Where
- China
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Colo-rectal Cancer
Plasma-based Colorectal Cancer Screening Research & Development
The objective of this Clinical Sample Collection Study is to develop a biobank of appropriately collected plasma samples from colorectal cancer patients (i.e.
- Trial name
- NCT04027790
- Testing
- Epi proColon
- Where
- 5 sites in United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Epigenomics, Inc
Colorectal Cancer, Colorectal Adenoma
The Colorectal Cancer Chemoprevention Acceleration and Improvement Platform (CRC-CHAMP) Study
The overall goal of this study is to develop a platform for both large-scale chemoprevention trials and real-world chemoprevention studies for colorectal cancer (CRC) prevention.
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Colorectal Adenomatous Polyp
- Trial name
- NCT05402124
- Testing
- acetylsalicylic acid delayed release tablets, 81mg
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Colorectal Cancer, CRC
Addressing Colorectal Cancer in South Florida Firefighters
The standard way of screening for colorectal cancer is to have a series of fecal blood tests, where a sample is taken from a participant's stool, or an endoscopic procedure performed by a doctor, where a camera is used to look…
- Trial name
- NCT05976282
- Testing
- Fecal Immunochemical Test, Septin9 Test
- Where
- United States
- Volunteers
- 646 people, healthy volunteers welcome
- Sponsor
- University of Miami
Colon Cancer, Rectal Cancer
GI SPORE Colon Biosample Protocol
The investigators are creating a data and specimen repository to study causes , early detection, prevention and treatment of colon and rectal cancer.
- Trial name
- NCT02243267
- Testing
- sample collection
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Colon Cancer, Polyps
Evaluation of Stool Tagging for Improved Patient Compliance
Computed tomography (CT) colonography has gained widespread multi-disciplinary interest as an evolving noninvasive colorectal screening examination, with the potential of improved patient compliance.
- Trial name
- NCT00124163
- Testing
- Imaging procedure of CT colonography
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Center for Diagnostic Imaging
Colorectal Cancer, Lung Cancer
Technology-Based Cancer Screening Intervention
The primary purpose of this research study is to contribute to generalized knowledge on how to increase screening for patients at risk of missing their recommended cancer preventive care by using a newly developed predictive…
- Conditions
- Colorectal Cancer, Lung Cancer, Breast Cancer
- Trial name
- NCT04535492
- Testing
- Decision Making Support Tool
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Colorectal Cancer, Sleep Apnea Syndromes
Prevalence of Sleep Apnea in Patients Undergoing Surgery for Colorectal Cancer
212 patients with colorectal cancer will be investigated before surgery and 100 of them after surgery. 597 individuals from a previous population based study will serve as controls to the prevalence of sleep apnea in the general…
- Conditions
- Colorectal Cancer, Sleep Apnea Syndromes, Hypoxia
- Trial name
- NCT02323464
- Testing
- Surgery for colorectal cancer, No Interventions
- Where
- Sweden
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Karl A Franklin
Adenoma, Adenoma Colon
Impact of AI on Trainee ADR
Adenoma detection rate (ADR) is a validated quality metric for colonoscopy with higher ADR correlated with improved colorectal cancer outcomes.
- Conditions
- Adenoma, Adenoma Colon, Colorectal Cancer
- Trial name
- NCT05423964
- Testing
- AI use in Endoscopy Room, Non-AI use Standard of Care endoscopy room
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Pelvic Radiation Therapy, Radiation-induced Hemorrhagic Cystitis
Trial Evaluating the Efficacy of Systemic Mesenchymal Stromal Cell (MSC) Injections for the Treatment of Severe and Chronic Radiotherapy-induced Abdomino-pelvic Complications (Pelvic Radiation Disease, PRD) Refractory to Standard Therapy
Patients receiving radiation therapy are still at risk for side effects due to off-target radiation damage of normal tissues The number of cancer patients is expected to increase from 14.1 million around the world in 2012 to 19.3…
- Trial name
- PRISME (NCT02814864)
- Testing
- Mesenchymal Stromal Cell (MSC) injections
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pancreatic Ductal Adenocarcinoma, Pancreatic Cyst
The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics
The long-term goal of our PIC is to develop effective strategies that can be applied clinically at the point-of-care to prevent, intercept, or detect PDAC at an early stage, thereby reducing PDAC burden and saving lives.
- Conditions
- Pancreatic Ductal Adenocarcinoma, Pancreatic Cyst, Chronic Pancreatitis, Fatty Pancreas
- Trial name
- NCT05692596
- Testing
- Data collection
- Where
- United States
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Nutrition Related Neoplasm/Cancer
Dietary Factors Associated to Colorectal Premalignant Lesions (COLOMAR-1)
This study aims to find a correlation between fish protein intake and other dietary habits and colorectal premalignant lesions in healthy volunteers.
- Trial name
- NCT06368661
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fundación Vithas
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