Clinical trials: Colonization
Complicated Intra-Abdominal Infections
Antibiotic Resistant Bacteria Among Patients With Severe Intraabdominal Infections
The objectives of the study were: 1. To study risk factors for colonization and infection with antibiotic resistant bacteria among patients with severe IAI before and after antibiotic treatment and surgical intervention. 2.
- Trial name
- Bakki (NCT00860587)
- Volunteers
- 200 people
- Sponsor
- University Hospital, Linkoeping
Chronic Hand Eczema
Microbial Colonization and Change of Chronic Keratinized Hand Eczema After Using Halometasone Triclosan
The clinical study of the microbial colonization of chronic keratinized hand eczema and the change of microbial colonization after external using of Halometasone Triclosan Cream
- Trial name
- MCCK (NCT03246776)
- Testing
- Halometasone Triclosan
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Friendship Hospital
Microbial Colonization
Preterm Infant Intestinal Microbiota Development and Maternal Fecal Transplant
The goal of this clinical trial is to study if a oral maternal fecal transplant given to a premature infant born by cesarean section (CS) is safe.
- Trial name
- PREFLOR (NCT06227845)
- Testing
- Fecal microbiota transplant
- Where
- Finland
- Volunteers
- 36 people
- Sponsor
- Otto Helve
Microbial Colonization
Impact of Quinoa Milk Fermented With Lactic Acid Bacteria From Foods on Human Oral and Intestinal Flora
The demand for alternatives to dairy products has increased in recent years and a lot of proposals for vegetable milk and yogurt products have taken place in the market.
- Trial name
- NCT04280731
- Testing
- fermented quinoa
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lund University
Infections, Bacterial
Retapamulin Ointment in Healthy Adults Nasally Colonized With Staphylococcus Aureus
This is a Phase I/IIa randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, PK, and efficacy of Retapamulin ointment, 1% applied twice daily for 3 or 5 days to the anterior nares of healthy…
- Trial name
- NCT00539994
- Testing
- retapamulin
- Where
- 4 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Growth
Evaluation of Safety, Growth, Tolerance and Effects on the Intestinal Fora of a New Milk for Healthy Infants
The purpose of the study is to assess growth and tolerance in new born and infant fed an experimental infant formula with reduced total protein concentration, enriched in alpha-lactalbumin and containing a symbiotic.
- Trial name
- Pétunia (NCT00920166)
- Testing
- Pétunia 1, Regular formula
- Where
- 4 sites in France
- Volunteers
- 97 people
- Sponsor
- Sodilac
Diarrhea
Dose-finding Study of WS6788A, DS37-4 and H10407 Enterotoxigenic Escherichia Coli (ETEC) Challenge Strains
Five subjects will be admitted to the General Clinical Research Center (GCRC). The next day they will eat a light breakfast, fast for 90 minutes, ingest ETEC strain H10407, and fast for 90 more minutes.
- Trial name
- NCT00198796
- Testing
- H10407
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Anastomotic Leak, Microbial Colonization
SURGIcal COmplication and MIcrobiome ChangeS in Colorectal Surgery
The microbiome, the collection of microorganisms that live in our gut, plays an important role in maintaining our health, proper nutrient absorption, nutrient turnover and immunity.
- Trial name
- Surgi-Comics (NCT05779254)
- Testing
- Neomycin Sulfate
- Where
- 3 sites in Hungary
- Volunteers
- 100 people
- Sponsor
- Uzsoki Hospital
Microbial Colonization
Rewilding the Human Gut: Reintroduction of the Species Limosilactobacillus Reuteri
The large intestine is home to trillions of microbes, known as the gut microbiome, which perform essential functions, such as digesting food and fighting disease.
- Trial name
- NCT03501082
- Testing
- L Reuteri PB-W1 Strain, L. Reuteri DSM20016T Strain, Non-Industrialized-Type Diet
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Lower Respiratory Tract Infection, Upper Respiratory Tract Infection
Antiviral Activity of Oral Probiotics
The aim of this study is to test saliva samples obtained from healthy human participants for anti-viral activity after they have consumed S. salivarius probiotic in a powder format.
- Trial name
- NCT05374070
- Testing
- Streptococcus salivarius K12 Powder 1 Billion colony forming units /g), Streptococcus salivarius K12 Powder (1 Billion colony forming units /g) with a prebiotic included, Streptococcus salivarius M18 Powder (1 Billion colony forming units /g)
- Where
- New Zealand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- John Hale
Group B Streptococcal Infection
Intrapartum Effect of Vancomycin on Rectovaginal GBS Colonization
The aim of this project is to identify the duration of vancomycin administration at which group B streptococcus (GBS) colonization is eradicated from the vaginal and recto-vaginal mucosa.
- Trial name
- NCT02814318
- Testing
- Vaginal and rectovaginal swab cultures
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Oncology [See Also, Affected System], Hematological Disease
Assessing the Effect of Contact Isolation on Nosocomial Colonization With ESBL-EC in German Hematology/Oncology Wards
This study aims to evaluate the impact of contact isolation on the rate of hospital-acquired transmissions of ESBL-producing Escherichia coli (ESBL-EC) and the rate of colonization and infection.
- Conditions
- Oncology [See Also, Affected System], Hematological Disease, Infection Due to ESBL Escherichia Coli
- Trial name
- CONTAIN (NCT02456818)
- Volunteers
- 2,264 people
- Sponsor
- University of Cologne
Antibiotic Resistant Strain, Microbial Colonization
Fecal Microbiota Transplantation for Eradication of Carbapenem-resistant Enterobacteriaceae Colonization
Antibiotic resistance has emerged world wide and is of major concern. Multidrug resistant (MDR) bacteria is widely spread and is now a major factor in morbidity and mortality in health-care settings.
- Trial name
- NCT03391674
- Testing
- Fecal Microbiota Transplantation
- Where
- Israel
- Sponsor
- Rambam Health Care Campus
GBS
QF-PCR In GBS Diagnosis During Pregnancy
Estimate the sensitivity and specificity of Quantitative Fluorescence Polymerase Chain Reaction (QF-PCR) in diagnosing Group B Strep (GBS) rectovaginal colonization during pregnancy, and follow the outcome of the mothers and…
- Trial name
- QFPCRIGDDP (NCT04434391)
- Testing
- QF-PCR for GBS screening
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Primary Teeth, Microbial Colonization
The Antibacterial Effect of Nanosilver Fluoride on Primary Teeth
To assess the antibacterial effect of Nanosilver Fluoride (NSF) in relation to caries activity in dentin caries lesions of primary teeth in comparison to Silver Diamine Fluoride (SDF).
- Conditions
- Primary Teeth, Microbial Colonization, Caries, Dental Caries in Children
- Trial name
- NCT05221749
- Testing
- Nanosilver Fluoride (NSF), Silver diamine fluoride
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nour Ammar, BDS
MRSA-Colonization
Whole Body Washing With Chlorhexidine for the Eradication of MRSA
The purpose of this study is to determine whether whole body washing with chlorhexidine in combination with mupirocine nasal ointment is effective in the eradication of meticillin-resistant Staphylococcus aureus (MRSA).
- Trial name
- NCT00266448
- Testing
- Chlorhexidine solution 4%
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Heidelberg University
Diarrhea
Low-dose Challenge Model With Enterotoxigenic E Coli
This study will validate a model for testing new vaccines designed to protect against intestinal infections with enterotoxigenic Escherichia coli (ETEC).
- Trial name
- NCT00844493
- Testing
- E coli strain H10407 and buffer, E coli H10407 and buffer
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Staphylococcus Aureus, HIV Infections
Mupirocin Ointment to Eliminate Nasal Carriage of Staphylococcus Aureus in HIV Infection
Staphylococcus aureus is a bacteria that causes serious, often life threatening infections including pneumonia, wound, and bloodstream infections. Persons with AIDS are at high risk for S. aureus infections.
- Trial name
- NCT00801879
- Testing
- Mupirocin calcium ointment, 2%
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Columbia University
Group B Streptococcus (GBS) Colonization
Group B Streptococcus Colonization in Mother-newborn Dyads and Association With Serotype-specific Capsular Antibodies in Karachi, Pakistan.
Group B Streptococcus (GBS) of which there are 10 serotypes of varying invasive potential is a major cause of invasive bacterial disease in neonates and young infants.
- Trial name
- GBS (NCT05469256)
- Where
- Pakistan
- Volunteers
- 600 people
- Sponsor
- Aga Khan University
Colic, Infantile, Probiotic
NEOBIFI: Clinical Trial for the Prevention and/or Reduction of the Incidence of Colics in Infants
Infant colics represent a clinical condition in childhood, characterized by an uncontrollable crying that occurs without any apparent organic cause.1 They can be associated with face redness, closed fists, thighs flexion…
- Conditions
- Colic, Infantile, Probiotic, Gut Microbiome, Bifidobacterium Breve
- Trial name
- NEOBIFI (NCT03219931)
- Testing
- Bifidobacterium breve BR03 and Bifidobacterium breve B632
- Where
- Italy
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita