Clinical trials: Colonoscopy
Colonoscopy
A Safety and Efficacy Comparison of BLI4700 Bowel Preparation Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy
The objective of this study is to compare the safety and efficacy of BLI4700 bowel preparation to an FDA-approved bowel preparation as 2-day, split-dose bowel preparations prior to colonoscopy in adult patients.
- Trial name
- NCT03261960
- Testing
- BLI4700, Magnesium bowel preparation
- Where
- 20 sites in United States
- Volunteers
- 389 people
- Sponsor
- Braintree Laboratories
Clostridium Difficile Infection Recurrence
A Multi-center, Single-arm Trial Exploring the Safety and Clinical Effectiveness of RBX2660 Administered by Colonoscopy to Adults With Recurrent Clostridioides Difficile Infection
This trial will be initiated to explore whether RBX2660 (REBYOTA®) could be suitable for administration by the practice of colonoscopy.
- Trial name
- CDI-SCOPE (NCT05831189)
- Testing
- RBX2660
- Where
- 12 sites in United States
- Volunteers
- 41 people
- Sponsor
- Ferring Pharmaceuticals
Colonoscopy
Safety and Efficacy of Remimazolam in ASA III and IV Patients Undergoing Colonoscopy
A prospective, double-blind, randomized, placebo and active controlled, multi-center, parallel group study comparing remimazolam to placebo, with an additional open-label arm for midazolam, in American Society of…
- Trial name
- NCT02532647
- Testing
- Remimazolam, Midazolam
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- Paion UK Ltd.
Colonoscopy
An Open-Label Preference Evaluation of BLI800
The purpose of this study is to evaluate patient experience ratings of BLI800 in adult patients undergoing colonoscopy.
- Trial name
- NCT04214301
- Testing
- BLI800
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Braintree Laboratories
Bowel Preparation
A Study Comparing the Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid Oral Solution With PREPOPIK® for Colon Cleansing in Preparation for Colonoscopy
The purpose of this study is to compare the Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid Oral Solution with PREPOPIK® for colon cleansing in adult subjects undergoing colonoscopy.
- Trial name
- NCT03017235
- Testing
- Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid Oral Solution, Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Powder
- Where
- 14 sites in United States, Canada
- Volunteers
- 917 people
- Sponsor
- Ferring Pharmaceuticals
CRC
Evaluation of the Motus Gl CleanUp System During Screening Colonoscopy
Motus Gl is developing a single-use device that attaches to a standard colonoscope, thereby integrating colon cleansing, screening and treatment into one procedure. The device creates turbulence within the colon using water jets.
- Trial name
- NCT02161549
- Testing
- Motus Gl CleanUp System
- Where
- Spain
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Colon Cancer
Polyp Detection With the EndoRings™: A Randomized Tandem Colonoscopy Study
To compare the adenoma miss rate with the EndoRings™ vs. the adenoma miss rate with Standard view colonoscopy. To compare the polyp miss rate with the EndoRings™ vs.
- Trial name
- NCT01955122
- Testing
- Tandem Colonoscopy
- Where
- 3 sites in United States, Israel and 1 more
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- EndoAid
Hypertension
A Study Evaluating the Gastrointestinal (GI) Safety and Tolerability of Aliskiren Compared to Ramipril in Essential Hypertension
This study will evaluate the long-term gastrointestinal (GI) safety and efficacy of aliskiren (300 mg) compared to ramipril (10mg) in patients ≥ 50 years with essential hypertension.
- Trial name
- NCT00631917
- Testing
- Aliskiren, Ramipril
- Where
- 7 sites in United States, Argentina and 5 more
- Volunteers
- 774 people
- Sponsor
- Novartis
Airway Obstruction, Apnea
Effectiveness of Continuous Negative External Pressure in Preventing Upper Airway Impairment During Routine Colonoscopy
The primary goal of this study is to determine the effectiveness and safety of delivering continuous negative external pressure (cNEP) to the upper airway as a means of preventing episodes of respiratory impairment (RI) such as…
- Conditions
- Airway Obstruction, Apnea, Hypopnea
- Trial name
- NCT01895062
- Testing
- Airway Management System (AMS)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- 5i Sciences, Inc.
Bowel Preparation
Investigation of PicoPrep Versus HalfLytely for Bowel Preparation for Colonoscopy - Day Before PicoPrep
Subjects undergoing an elective complete colonoscopy will randomly receive either PicoPrep: 2-sachets for oral solution in two divided doses given in the afternoon (first dose - sachet) and 6 hours later in the evening (second…
- Trial name
- NCT01073943
- Testing
- PicoPrep, HalfLytely, bisacodyl
- Where
- 11 sites in United States
- Volunteers
- 603 people
- Sponsor
- Ferring Pharmaceuticals
Colonoscopy, Bowel Preparation
BLI800-480: A Safety and Efficacy Evaluation of 2 Different Bowel Cleansing Preparations in Adult Subjects
To compare the safety, tolerance and efficacy of SUPREP Bowel Prep Kit to an FDA approved control as bowel preparations prior to colonoscopy in adult patients.
- Conditions
- Colonoscopy, Bowel Preparation, Endoscopy
- Trial name
- NCT01786629
- Testing
- SUPREP Bowel Prep Kit, FDA approved bowel preparation containing electrolytes
- Where
- 10 sites in United States
- Volunteers
- 338 people
- Sponsor
- Braintree Laboratories
Colonoscopy
Study 302: BLI4900 Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy
The purpose of this study is to compare the safety and efficacy of BLI4900 bowel preparation to an FDA-approved control as 2-day, split-dose bowel preparations prior to colonoscopy in adult patients.
- Trial name
- NCT04446312
- Testing
- Bowel Prep
- Where
- 34 sites in United States
- Volunteers
- 500 people
- Sponsor
- Braintree Laboratories
Colonoscopy Procedure
Evaluation of the Performance of the Motus Cleansing System
The purpose of this study is evaluate the Motus GI Colon Cleansing system performance.
- Trial name
- MSC (NCT02161536)
- Testing
- Motus Cleansing System
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Bowel Preparation
Investigation of PicoPrep Versus HalfLytely for Bowel Preparation for Colonoscopy - Split Dose PicoPrep
Subjects undergoing an elective complete colonoscopy will randomly receive either PicoPrep: 2-sachets for oral solution in two divided doses given a night before (first dose - sachet) and approximately 5 hours prior to procedure…
- Trial name
- NCT01073930
- Testing
- PicoPrep, HalfLytely, bisacodyl
- Where
- 9 sites in United States
- Volunteers
- 608 people
- Sponsor
- Ferring Pharmaceuticals
Colonoscopy Preparation
2 Regimens of Lactulose for Colonoscopy Preparation in Adults
The purpose of the study is to determine the efficacy of 2 regimens of lactulose as a preparation for colonoscopy.
- Trial name
- NCT01887470
- Testing
- Full dose preparation, Split dose preparation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Cumberland Pharmaceuticals
Colonoscopy, Bowel Preparation
A Safety Study of 3 Different Bowel Cleansing Preparations
The objective of this study is to compare the safety, tolerance and efficacy of BLI800 (approved and investigational regimens) to an approved control preparation as bowel preparations prior to colonoscopy in adult patients…
- Conditions
- Colonoscopy, Bowel Preparation, Endoscopy
- Trial name
- NCT01501513
- Testing
- PEG-3350 based bowel preparation, BLI800 approved preparation regimen, BLI800 investigational preparation regimen
- Where
- 17 sites in United States
- Volunteers
- 541 people
- Sponsor
- Braintree Laboratories
Bowel Cleansing
A Trial Comparing the PICOPREP Tailored Dosing Schedule to the PICOPREP Day-before Dosing Schedule for Colon Cleansing in Preparation for Colonoscopy
This was a phase 3, randomised, assessor-blinded, multi-centre trial comparing the efficacy, safety and tolerability of a PICOPREP tailored dosing schedule to the PICOPREP day-before dosing schedule for colon cleansing in…
- Trial name
- OPTIMA (NCT02239692)
- Testing
- PICOPREP
- Where
- 3 sites in France, Germany and 1 more
- Volunteers
- 204 people
- Sponsor
- Ferring Pharmaceuticals
Polyps
Evaluation of an Endoscopic Suturing System for Tissue Apposition in Colonic Polypectomy
The purpose of this study is to show that the surgical site in the bowel wall can be sewn closed in the colon or intestine, with a new sewing device after removal of a benign polyp according to standard of care.
- Trial name
- NCT00553436
- Testing
- Tissue Apposition System (TAS) Device
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Ethicon Endo-Surgery
Colon Cleansing in Preparation for Colonoscopy
A Phase III Study With FE 999169 Versus Niflec for Colon Cleansing
To demonstrate non inferiority of a) "FE 999169 Split Dosing Schedule" (one dose on the day before and the second dose on the day of colonoscopy) and b) "FE 999169 Day Before Dosing Schedule" (two doses on the day before…
- Trial name
- NCT02215954
- Testing
- FE 999169, Niflec
- Where
- 4 sites in Japan
- Volunteers
- 637 people
- Sponsor
- Ferring Pharmaceuticals
Adenoma, Polyps
Prospective Trial to Compare the Clinical Efficiency of G-EYE™ HD Colonoscopy With Standard HD Colonoscopy
The purpose of this study is to compare the adenoma detection rate of G-EYE™ high definition colonoscopy with that of standard high definition colonoscopy
- Conditions
- Adenoma, Polyps, Colorectal Cancer
- Trial name
- NCT01917513
- Testing
- G-EYE™ colonoscopy, Standard Colonoscopy
- Where
- 15 sites in United States, Denmark and 6 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.