Clinical trials: Colonoscopy Procedure
Colon Cancer, Colon Rectal Cancer
EndoStyle: Artificial Intelligence Image Transformation Tool for Colonoscopy
The study addresses the limitations of current AI systems in gastrointestinal endoscopy, which are tipically trained with data from a single type of endoscopy processor and have limited expert-annotated images.
- Trial name
- EndoStyle (NCT06553326)
- Testing
- EndoStyle
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Healthy Person, Bowel Preparation Before Colonoscopy
Comparison Between 2L Coolprep® and Combination of 1L Coolprep® and Bisacodyl as Bowel Preparation
comparison of the use of Colyte® (ascorbic acid mixed polyethylene glycol solution) in two-liter versus one-liter volume and pretreatment with bisacodyl for colonoscopy preparation.
- Trial name
- NCT01745835
- Testing
- 2L Coolprep®, 1L Coolprep® and Bisacodyl
- Where
- South Korea
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Colorectal Cancer Screening
Comparison of Transparent Retractable Extension Device and Narrow Band Imaging on Colorectal Adenoma Detection
The investigators previously reported that colonoscopy with a transparent retractable extension (TRE) device improved the adenoma detection rate without affecting intubation and withdrawal times.
- Trial name
- NCT00765180
- Testing
- TRE vs. NBI
- Where
- Japan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Showa Inan General Hospital
Patients Scheduled for Colonoscopy
Linaclotide for Colonoscopy Bowel Prep
The goal of this clinical trial is to learn if drug Linaclotide can be used as a single agent regimen to adequately prepare bowel for colonoscopy.
- Trial name
- NCT06692673
- Testing
- Use of Linaclotide as a single agent Colonoscopy prep
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pain
Electrical Stimulation Over Acupuncture Points in Reduction of Rectal Discomfort Distension
Colonoscopy is a stressful and unpleasant procedure especially during the passage of the endoscope through angulations of colon. Electro-acupuncture is one of the alternative to reduce colorectal discomfort.
- Trial name
- NCT01551654
- Testing
- Transcutaneous Electrical Nerve Stimulation (ITO Company )
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Patient Satisfaction
Use of Virtual Reality Technology as a Sedation Replacement During Colonoscopy
A pilot non-randomized controlled study examined whether the use of VR technology can serve as an appropriate substitute for sedation in a colonoscopy examination.
- Trial name
- NCT05701566
- Testing
- virtual reality headset, colonoscopy with standard sedation.
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Colonoscopy
Thorough Flushing Strategy During Colonoscopy Examination
The investigators plan to adopt a thorough flushing strategy when withdrawing the endoscope, and have zero tolerance for the liquid and foam in the intestinal lumen.
- Trial name
- NCT06117553
- Testing
- thorough flushing
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Bowel Disease
Plenvu 1 - Questionnaire Study Exploring Patients Preference in Bowel Preparation Timings for Morning Colonoscopy
Questionnaire study exploring patients preference in bowel preparation timings for morning colonoscopy.
- Trial name
- NCT04456790
- Where
- United Kingdom
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Colonoscopy, Bowel Preparation
Acid-base Balance in Patients Undergoing Colonoscopy
The purpose of this study is to determine whether fluid administration in patients undergoing colonoscopy should affect acid-base disorder in term of the strong ion differences.
- Trial name
- NCT01250886
- Testing
- Lactated Ringer's solution, Normal saline solution, Acetate Ringer's solution
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Colonoscopy
Bispectral Index Monitoring for Sedation in Elective Colonoscopies of Adult Patients: a Randomized Controlled Trial
The primary aim of the study is to determine the rate sedation-induced adverse events, comparing BIS-guided sedation with clinical observation.
- Trial name
- BIS (NCT03453359)
- Testing
- BIS monitor, Ramsay scale
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hospital Galdakao-Usansolo
Colonoscopy
Morning-Only 4 L PEG vs Split Dose Prep for Afternoon Colonoscopies, Endoscopist-Blinded Prospective Study
Comparison of quality of preparation of colonoscopy in patients taking same day 4L preparation vs. 4 L split dose preparation in patients scheduled for an afternoon colonoscopy procedure.
- Trial name
- NCT02643316
- Testing
- Same day 4 L preparation (Polyethylene Glycol), Split dose 4 L preparation (Polyethylene Glycol)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Procedural Anxiety, Procedural Pain
VR Augmented Human Delivered Integrative Psychotherapy for Colonoscopy Procedural Anxiety and Pain
Colonoscopy is an invaluable tool for the diagnosis and management of colon diseases, especially colorectal cancer (CRC) - the third most common cancer worldwide.
- Trial name
- VRIPanx-COL (NCT06346171)
- Testing
- Virtual Reality Integrative Psychotherapy, Virtual Reality Distraction
- Where
- Romania
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Colorectal Polyps
Research on the Application of AI Image Recognition-Based Smartphone Apps in Personalized Bowel Preparation
Colorectal cancer, as one of the most common malignant tumors of the digestive system, has a high incidence and mortality rate worldwide.
- Trial name
- NCT06610630
- Testing
- Assessment of Bowel Preparation Using AI-Driven Smartphone Applications
- Where
- China
- Volunteers
- 513 people, healthy volunteers welcome
- Sponsor
- Jianning Yao
Artificial Intelligence, Colonoscopy
Artificial Intelligence-assisted Colonoscopy for Detection of Colon Polyps
All subjects shall sign informed consent before screening, and subjects shall be included according to inclusion and exclusion criteria.
- Trial name
- NCT04126265
- Testing
- Artificial intelligence assisted colonoscopy
- Where
- China
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Side Liu
Colorectal Cancer, Colorectal Polyp
Accuracy for Predicting Deep Submucosal Invasion
The main aim of this study is to determine whether the assessment of the invasive pattern based on NBI with dual focus/magnification or BLI with magnification ± chromoendoscopy (NBI+CE) for predicting deep invasion is…
- Trial name
- NBIBLI (NCT03748667)
- Testing
- White light endoscopy (WLE), NBI/BLI +/- chromoendoscopy (NBIBLI +/- CE)
- Where
- 14 sites in United States, Japan and 1 more
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Predictive Cancer Model
Innovative Approach to Detect Recurrent Colorectal Lesions With Surveillance Via Mutation Analysis & Clinical Phenotype
It is known that the development of colorectal adenoma is dependent on the appearance of somatic mutations in protooncogenes and tumor suppressor genes.
- Trial name
- MTG (NCT05929365)
- Testing
- colonoscopy
- Where
- Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Military University Hospital, Prague
Colorectal Cancer
Informed Choice - Compass
The primary objective of this study is to evaluate the impact of a theoretically grounded video that includes information about CRC screening modality choices on CRC screening rates and time adherent to CRC guidelines.
- Trial name
- NCT05246839
- Testing
- Brief Video, Brief Video Plus
- Where
- 39 sites in United States
- Volunteers
- 1,823 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Colonic Adenoma, Colonic Cancer
R vs L Lateral Decubitus Positioning in Colonoscopy
Colonoscopy continues to be the gold standard in detecting precancerous lesions in the colon. It relies on adequate visualization of the bowel wall to see and remove such lesions.
- Trial name
- NCT03355495
- Testing
- Colonoscopy - Position Change
- Where
- Canada
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Performance of Inappropriate Operation
Simulator Training for Gastrointestinal Endoscopy
This is a randomized controlled trial evaluating three training intervals using an endoscopy simulator for novices and comparing performance after training.
- Trial name
- NCT01405443
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Colonoscopy
Will Cap-Assisted Colonoscopy Improve Performance of Colonoscopy: A Randomized Clinical Trial
Observing the effects of an Olympus cap on the visibility and in adenoma detection during colonoscopy.
- Trial name
- CAC (NCT01126632)
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority