Clinical trials: Colonoscopy Procedure
Colon Cancer Screening, Colon Polyps
Comparison of Colon Adenoma Detection Rate Using Two Distal Colonoscope Attachments
The goal of this study is to compare two FDA approved distal colonoscope attachment devices, in order to identify which device can increase adenoma detection rate the most without increasing procedure time or risk.
- Conditions
- Colon Cancer Screening, Colon Polyps, Colon Adenomas, Water Exchange Colonoscopy
- Trial name
- NCT02665741
- Testing
- Olympus transparent cap, Medivators Endocuff, Control
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of California, Davis
Colorectal Cancer
Comparing the Effectiveness of Written Vs Verbal Advice for First Degree Relatives of Colorectal Cancer Patients
CRC patients were enrolled and asked about their FDR contacts These FDRs were telephoned and enrolled and randomized to receive either written advice and verbal advice about their cancer risk and screening methods.
- Trial name
- NCT06242197
- Testing
- written advice
- Where
- Thailand
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ramathibodi Hospital
Diverticular Disease, Diverticulitis
Confocal Laser Endomicrospy in Colonic Diverticular Disease
Confocal laser endomicroscopy detects inflammatory markers undetectable during high definition endoscopy. The investigators aimed to evaluate the role of peridiverticular and colonic mucosa inflammation in the prediction of the…
- Conditions
- Diverticular Disease, Diverticulitis, Diverticula
- Trial name
- NCT04173182
- Testing
- Probe-based confocal laser endomicroscopy evaluation
- Where
- Ecuador
- Volunteers
- 63 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Post Polypectomy Bleeding
A Trial on Prophylactic Clipping to Prevent Post-polypectomy Bleeding After Colonoscopy in Direct Oral Anticoagulant Users
The investigators hypothesize that prophylactic clipping after colonoscopic polypectomy can reduce risk of delayed PPB among DOAC users.
- Trial name
- PROCLIP (NCT05169242)
- Testing
- Endoclip
- Where
- Hong Kong
- Volunteers
- 584 people
- Sponsor
- Chinese University of Hong Kong
Colonoscopy
The Study on the Effect of Different Administration Methods of Simethicone in Reducing Bubbles During Bowel Preparation
To find the simplest and most effective method of intestinal preparation for dimethicone administration.
- Trial name
- NCT06919120
- Testing
- Simethicone is mixed into the final packet of compound polyethylene glycol electrolyte powder, Take simethicone separately
- Where
- China
- Volunteers
- 3 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Colorectal Neoplasms
Computer Assisted Detection of Neoplasia During Colonoscopy Evaluation
The goal of this cluster randomized study is to determine if artificial intelligence systems used during colonoscopy can improve the detection of precancerous polyps in the colon.
- Trial name
- CADeNCE (NCT05888623)
- Testing
- Computer Assisted Detection
- Where
- United States
- Volunteers
- 334,200 people
- Sponsor
- VA Puget Sound Health Care System
Colorectal Cancer (Diagnosis)
Colorectal Lesion Evaluation and Appropriate Resolution (CLEAR) Study
The primary objective of this study is to evaluate a blood-based screening test for Colorectal Cancer (CRC).
- Trial name
- CLEAR (NCT07479381)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Harbinger Health
Any Symptom Requiring Colonoscopy
Evaluation of 3-Dimensional Magnetic Imaging During Colonoscopy
A commercial 3-dimentional magnetic imaging system (Olympus ScopeGuide) is available for routine use during colonoscopy. No randomised trials have been performed to evaluate if, and to what extent, the use of this technology may…
- Trial name
- NCT00258531
- Testing
- Olympus ScopeGuide®, 3-dimentional magnetic imager
- Where
- Norway
- Volunteers
- 360 people
- Sponsor
- Sykehuset Telemark
Colorectal Polyp, Colorectal Cancer
Detection of Endoscopic Resection Scars and Delineation of Recurrence is Trainable
Colorectal cancer is prevented by colonoscopy and polypectomy. Failure to recognize the endoscopic resection scar after Endoscopic Mucosal Resection (EMR) risks unrecognized recurrent or residual adenoma (RRA), which may…
- Trial name
- SCAR (NCT06193356)
- Testing
- Learning tool
- Where
- Belgium
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Adenoma Detection Rate, Colonoscopy
Can Overall Adenoma Detection Rate Replace Screening Adenoma Detection Rate ? Multicenter Study
This is a prospective equivalence colonoscopy study evaluating whether overall adenoma detection rate (ADR) is a reliable alternate for screening ADR.
- Trial name
- NCT05125939
- Testing
- Comparison of ADR
- Where
- 6 sites in United States, Taiwan
- Volunteers
- 2,707 people
- Sponsor
- Evergreen General Hospital, Taiwan
Colonoscopy, Colon Polyps
A Study of AQUAVAN® Injection in the Presence of Pre-Medication in Patients Undergoing Elective Colonoscopy
This study was designed to assess the safety and efficacy of AQUAVAN® Injection in providing adequate sedation in patients undergoing colonoscopy.
- Trial name
- NCT00209534
- Testing
- fospropofol disodium
- Volunteers
- 200 people
- Sponsor
- Eisai Inc.
Liver Disease
Propofol and Remifentanyl Versus Midazolam and Fentanyl for Diagnostic Colonoscopy in Patients With Compensated Cirrhosis Child A-B
This is a prospective, randomized-controlled trial (RCT) comparing the use of Propofol and Remifentanyl and traditional sedation (Midazolam and Fentanyl) for diagnostic colonoscopies in patients with compensated cirrhosis child…
- Trial name
- NCT01148277
- Testing
- Propofol and Remifentnyl, midazolam and fentanyl, midazolam anf fentanyl
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Ziv Hospital
Colonic Diseases
Effect of Magnetic Endoscopic Imaging on Patient Pain During Colonoscopy
Colonoscopy is widely considered as the main choice for patients with suspected colorectal disease,and for screening those at high risk of colorectal cancer.
- Trial name
- NCT02681692
- Testing
- Magnetic endoscopic imaging system
- Where
- China
- Volunteers
- 594 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Colonic Neoplasms
Retroview™ Colonoscope and Lesion Detection Rate
Colonoscopy is considered the gold standard for colorectal polyp and cancer detection. However, even meticulous colonoscopy substantial numbers of colorectal polyps may be missed and carcinomas may not be prevented.
- Trial name
- NCT03155165
- Testing
- Retroview™ colonoscope
- Where
- Ecuador
- Volunteers
- 100 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Colorectal Cancer Prevention
Improve Colorectal Cancer Prevention by Motivational and Community-based Approaches
It has been estimated that 19,000 Colorectal Cancers (CRC) could be prevented each year in France by changing individual risk behaviours (sedentary lifestyle, overweight, diet, alcohol).
- Trial name
- NCT05568667
- Testing
- Low risk, Moderate risk, High risk
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre Leon Berard
Bowel Preparation
A Trial of Four Different Bowel Cleansing Regimens Prior to Colonoscopy
To compare 4 commonly used bowel preparations in terms of efficacy, patient tolerability and safety. All these 4 bowel preparations are likely to be efficacious and safe.
- Trial name
- NCT00831064
- Testing
- colonoscopy bowel prep
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Colonic Neoplasms, Inflammatory Bowel Diseases
IBD Neoplasia Surveillance RCT
We will conduct a multicenter, parallel-group, non-inferiority RCT in persons with IBD undergoing colorectal neoplasia screening with high-definition white light colonoscopy, comparing a strategy of sampling visible lesions alone…
- Conditions
- Colonic Neoplasms, Inflammatory Bowel Diseases, Dysplasia
- Trial name
- NCT05809999
- Testing
- Standard colonoscopy with targeted biopsies
- Where
- 11 sites in Canada
- Volunteers
- 1,411 people
- Sponsor
- Ottawa Hospital Research Institute
Colonoscopy Procedures, Sedation
Effects of Low-Dose Ketamine Added to Propofol Sedation During Colonoscopy
"This prospective observational study aims to evaluate the effects of adding low-dose ketamine (0.25 mg/kg) to standard propofol sedation on hemodynamic stability, sedation depth, and recovery times in adult patients undergoing…
- Trial name
- NCT07809230
- Testing
- Propofol group, Propofol + Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ankara Etlik City Hospital
Colonoscopy
The Effect of Virtual Reality Application on Pain, Anxiety, and Embarrassment During Colonoscopy
This study will be conducted to determine the effects of virtual reality (VR) intervention applied during colonoscopy performed without sedation on pain, anxiety, embarrassment, and physiological parameters.
- Trial name
- COLONOSCOPY (NCT07853300)
- Testing
- Virtual Reality (VR) Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Wound Endoscopical, Colon, After Polyp Resection, Colon
Efficacy of EndoClot™ Spraying After Endoscopic Resection of Large Colorectal Polyps
The effectiveness of colonoscopy in reducing colorectal cancer mortality relies on the detection and removal of neoplastic polyps.
- Trial name
- EndoClot™ (NCT05029934)
- Testing
- use of EndoClot
- Where
- 5 sites in Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
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