Clinical trials: Colonoscopy Procedure
Colonoscopy, Histology
In Vivo Computer-aided Prediction of Polyp Histology on White Light Colonoscopy
Our group, prior to the present study, developed a handcrafted predictive model based on the extraction of surface patterns (textons) with a diagnostic accuracy of over 90%24.
- Conditions
- Colonoscopy, Histology, Computer-aided Diagnosis, Artificial Intelligence
- Trial name
- NCT03775811
- Testing
- AUTOMATED POLYP CLASSIFICATION
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Clinic of Barcelona
Bowel Preparation for Colonoscopy
Split Dose Pico-Salax + Bisacodyl vs. PEG Split Dose
The objective of this study is to compare the efficacy, safety and tolerability of two bowel preparations for colonoscopy - split dose Polyethylene Glycol-Based Lavage and Pico-Salax plus Bisacodyl - with a specific emphasis on…
- Trial name
- BP (NCT01415687)
- Testing
- Polyethylene Glycol-Based Lavage, Pico-Salax (Magnesium Citrate) plus Bisacodyl
- Where
- 2 sites in Canada
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Colonic Polyps, Surveillance
Large Overuse of Post-polypectomy Surveillance Colonoscopy
In colorectal cancer screening era a huge burden of medical resources has been applied to surveillance. Although the adherence to post-polipectomy recommendations is a advocated as a mainstay for quality assurance colonoscopy…
- Conditions
- Colonic Polyps, Surveillance, Colonoscopy
- Trial name
- NCT01458093
- Testing
- colonoscopy
- Where
- Italy
- Volunteers
- 7,081 people
- Sponsor
- Valduce Hospital
Colon Cancer, Colon Adenomas
Plasma ctDNA in Patients Undergoing Diagnostic Colonoscopy
When the DNA inside of human cells undergoes certain alterations (mutations), the cells may develop into a cancer. The cancer cells may shed this DNA into the blood stream.
- Conditions
- Colon Cancer, Colon Adenomas, Colon Polyps
- Trial name
- NCT02665299
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Pathway Genomics
Colonic Polyp, Colonic Adenoma
Nationwide Study of Artificial Intelligence in Adenoma Detection for Colonoscopy
The goal of this trial is to determine whether use of a Computer Assisted Detection (CADe) programme leads to an increase in ADR for either units or individual colonoscopists, independent of setting or expertise
- Conditions
- Colonic Polyp, Colonic Adenoma, Colo-rectal Cancer
- Trial name
- NAIAD (NCT05870332)
- Testing
- GI Genius (GIG)
- Where
- United Kingdom
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Bowel Preparation Before Colonoscopy
A Safety and Efficacy Study of DCL-101 Compared to GoLYTELY
The primary objective of this Phase 2 Study was to compare the safety of 3 liter(L) and 4 liter(L) split dose DCL-101 to split dose 4L GoLYTELY in patients preparing for colonoscopy, with secondary objectives to assess…
- Trial name
- NCT02910440
- Testing
- DCL-101 vs Golytely
- Where
- 5 sites in United States
- Volunteers
- 46 people
- Sponsor
- Dark Canyon Laboratories, LLC
Oxygen Desaturation, Apnea (Central and Obstructive)
Supplemental Oxygen and Oxygen Desaturations in Colonoscopies
This study will compare apnea and oxygen desaturation events among various methods of supplemental oxygen delivery during procedural sedation in colonoscopy patients.
- Conditions
- Oxygen Desaturation, Apnea (Central and Obstructive), Airway Obstruction
- Trial name
- NCT07515755
- Testing
- Breath-synchronized oxygen, CPAP, Control
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Utah
Colorectal Cancer
Text Messaging to Improve Adherence To Repeat Colonoscopy In a Veterans Affairs (VA) Hospital
Colorectal cancer is a common but preventable condition, and increasing colorectal cancer screening is one of the most impactful public health contributions in the field of gastroenterology.
- Trial name
- NCT06185374
- Testing
- Text Message Instructions/Motivation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
the Difficulty of Colonoscopy Insertion
A Study on a New Indicator for Assessing the Difficulty of Colonoscopy Insertion and Its Related Factors
This study will include adult patients undergoing painless colonoscopy at our hospital. The time required for endoscope insertion to reach the cecum (Cecal Intubation Time, CIT) by physicians of different experience levels will…
- Trial name
- NCT07228715
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Second Hospital of Jilin University
Colonoscopy, Colon Disease
Three Distraction Methods for Pain Reduction During Colonoscopy
Colonoscopy is a common procedure to evaluate the gastrointestinal tract. The colonoscopy procedure can sometimes be uncomfortable and painful for the patient.
- Trial name
- NCT05378165
- Testing
- Music group, Stress ball group, Video group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Pain
Nitrous Oxide for Analgesia During Colonoscopy
The purpose of the study is to determine the analgetic effect of nitrous oxide during colonoscopy, compared to no sedation and intravenous (IV) sedation.
- Trial name
- NCT00318825
- Testing
- Nitrous oxide
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Rikshospitalet University Hospital
Colonoscopy Preparation
PEG Versus PEG+Bisacodyl Versus Sennosides for Colon Cleansing Before Colonoscopy
Background: Polyethylene glycol (PEG) solution has been proven to be effective for large bowel cleansing prior to colonoscopy in children.
- Trial name
- NCT01531140
- Testing
- polyethylene glycol +Bisacodyl, Polyethylene glycol, Sennosides
- Where
- 2 sites in Poland
- Volunteers
- 240 people
- Sponsor
- Medical University of Warsaw
Ulcerative Colitis
Indigo Carmine Staining and Narrow Band Imaging (NBI) of Colonic Mucosa for Detection of Dysplasia in Ulcerative Colitis
A prospective, randomized trial to determine indigo carmine dye spraying and narrow band imaging (NBI) of colonic mucosa to detect dysplasia in ulcerative colitis (UC).
- Trial name
- NCT00961948
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Bowel Preparation for Colonoscopy
Bowel Preparation for Repeat Colonoscopy After Preparation Failure (RepeatPrep Study)
This trial will evaluate the efficacy in colon cleansing of a nurse-led educational telephone intervention 24-48 hours before a colonoscopy, in selected participants with a previous inadequate bowel preparation.
- Trial name
- NCT03055689
- Testing
- Educational telephone intervention, Standard education for colonoscopy
- Where
- 14 sites in Spain
- Volunteers
- 657 people
- Sponsor
- Parc de Salut Mar
Health Behavior
Effect of Single Dose of 2L PEG on Bowel Preparation in Average-risk Patients Undergoing Colonoscopy
Adequate quality of bowel preparation(BP) is important for colonoscopy. Several guidelines recommend that split-dose of 4L PEG should be used as a standard regime for BP.
- Trial name
- NCT02998255
- Testing
- Single dose of 2L PEG, Split dose of 4L PEG
- Where
- 3 sites in China
- Volunteers
- 940 people
- Sponsor
- Air Force Military Medical University, China
Healthy
Evaluation of PICOLIGHT Plus COOLPREP, PICOLIGHT Plus CLICOLON for Bowel Preparation
The purpose of this study to bowel cleansing evaluation of mixed two other type bowel preparation drug(PICOLIGHT plus COOLPREP, PICOLIGHT plus CLICOLON).
- Trial name
- NCT01919255
- Testing
- Picolight + Coolprep, Picolight + Clicolon
- Where
- South Korea
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Screening Test, Endoscopy
The Alberta Primary Care Endoscopy (APC-Endo) Study
It is hypothesized that primary care colonoscopists are able to achieve benchmarks in colonoscopy quality including cecal intubation and adenoma detection rates and serious adverse event rates.
- Conditions
- Screening Test, Endoscopy, Colon Disease
- Trial name
- APC-Endo (NCT01320826)
- Testing
- colonoscopy
- Where
- 13 sites in Canada
- Volunteers
- 577 people
- Sponsor
- University of Alberta
Bowel Preparation
A Study Comparing the Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid Oral Solution With PREPOPIK® for Colon Cleansing in Preparation for Colonoscopy
The purpose of this study is to compare the Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid Oral Solution with PREPOPIK® for colon cleansing in adult subjects undergoing colonoscopy.
- Trial name
- NCT03017235
- Testing
- Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid Oral Solution, Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Powder
- Where
- 14 sites in United States, Canada
- Volunteers
- 917 people
- Sponsor
- Ferring Pharmaceuticals
Colorectal Cancer
Clinical Validation of An Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, for Colorectal Cancer Screening "BLUE-C"
The primary objective of this study is to assess the sensitivity for colorectal cancer (CRC) and specificity of the mt-sDNA 2.0 test.
- Trial name
- NCT04144738
- Testing
- mt-sDNA 2.0 screening test, FIT test, Colonoscopy
- Where
- 195 sites in United States
- Volunteers
- 26,758 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Colonoscopy, Lower Gastrointestinal Tract
A Study to Assess Cap-Assisted Colonoscopy Versus Regular Colonoscopy for the First or Repeated Colonoscopy
The primary aim of the study is to increase the success rate of cecal intubation in first colonoscopy and in repeated colonoscopy for the first failed procedure.
- Trial name
- CAC (NCT00153647)
- Testing
- Cap-assisted colonoscopy
- Where
- 2 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Chinese University of Hong Kong
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