Clinical trials: Colonoscopy Procedures
Conscious Sedation
An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Colonoscopy
Very often patients receive medication before a diagnostic procedure, like a colonoscopy, to help them relax and stay calm during the procedure. This is called procedural or minimal-to-moderate sedation.
- Trial name
- NCT00261599
- Testing
- AQUAVAN® (fospropofol disodium) Injection, Midazolam HCI
- Where
- 20 sites in United States
- Volunteers
- 300 people
- Sponsor
- Eisai Inc.
Colon Adenoma, Polyp of Colon
RITUAL Ultivision AI CADe Randomized Controlled Trial
Ultivision AI is a computer-assisted detection (CADe) device intended to aid endoscopists in the real-time identification of colonic mucosal lesions (such as polyps and adenomas).
- Conditions
- Colon Adenoma, Polyp of Colon, Adenoma Colon
- Trial name
- RITUAL (NCT05732233)
- Testing
- Ultivision AI
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 137 people
- Sponsor
- Satisfai Health, Inc.
Gastrointestinal Diseases
A Phase IV Study, of the Efficacy, Safety, and Acceptability of Moviprep® Versus Colopeg® in Colonoscopy Preparation
Primary: To demonstrate the superiority of Moviprep® versus Colopeg® in gut cleansing prior to colonoscopy. Secondary: To assess the safety of Moviprep® versus Colopeg®. To assess acceptability of Moviprep® versus Colopeg®.
- Trial name
- NORMO (NCT00605228)
- Testing
- MOVIPREP, COLOPEG
- Where
- 21 sites in France
- Volunteers
- 400 people
- Sponsor
- Norgine
Colonic Polyps, Adenomatous Polyps
ColoMaia II Software to Support Lesion Detection During Colonoscopy
The goal of this clinical trial is to learn whether the ColoMaia II software can help doctors find colon lesions during colonoscopy and whether it is safe to use in adults aged 40 to 80 years having screening, surveillance, or…
- Conditions
- Colonic Polyps, Adenomatous Polyps, Colorectal Neoplasms
- Trial name
- NCT07563816
- Testing
- ColoMaia II software, Standard colonoscopy
- Where
- 3 sites in Czechia
- Volunteers
- 600 people
- Sponsor
- MAIA Labs s.r.o.
Colonoscopy, Colorectal Cancer Screening
Triton 1.5 Robotic System for Diagnostic Colonoscopy
This study is a prospective, single-arm, non-randomized, single-site study, focused on evaluating the safety and efficacy of the Triton 1.5 System in diagnostic and basic therapeutic colonoscopy.
- Trial name
- CARE II (NCT07606963)
- Testing
- Diagnostic Test: Diagnostic Colonoscopy
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Bowel Preparation Prior to Endoscopic, Radiological and Other Examinations as Well as to Surgical Procedures Which Require Empty Bowel.
Evaluation of the Efficacy, Safety and Tolerance of Experimental Morning-only MOVIPREP® Bowel Preparation in Comparison With Split-dose With Nocturnal Pause MOVIPREP® Bowel Preparation
To compare colon cleansing quality induced by the 2 different modes of MOVIPREP® intake in 5 colon segments prior to colonoscopy.
- Trial name
- NCT01732692
- Testing
- MOVIPREP
- Where
- 3 sites in Kazakhstan, Russia
- Volunteers
- 140 people
- Sponsor
- Takeda
Colorectal Screening
Demonstrating Effective Salvage of Inadequate Colonoscopies
The aim of this study is to demonstrate that the use of the Pure-Vu EVS System can salvage inadequately prepared optical colonoscopies (OCs) to adequate OCs.
- Trial name
- NCT05585879
- Testing
- Pure-Vu EVS
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Bowel Disease
Phase Ⅱ Dose Response Study of NPO-13 in Patients Undergoing Total Colonoscopy
Patients who require screening colonoscopy will receive an intraluminal spraying of NPO-13 per contraction region of large bowel up to fifth times during the colonoscopy.
- Trial name
- NCT02265939
- Testing
- NPO-13
- Where
- 3 sites in Japan
- Volunteers
- 132 people
- Sponsor
- Nihon Pharmaceutical Co., Ltd
Colon Cancer
Polyp Detection With the EndoRings™: A Randomized Tandem Colonoscopy Study
To compare the adenoma miss rate with the EndoRings™ vs. the adenoma miss rate with Standard view colonoscopy. To compare the polyp miss rate with the EndoRings™ vs.
- Trial name
- NCT01955122
- Testing
- Tandem Colonoscopy
- Where
- 3 sites in United States, Israel and 1 more
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- EndoAid
Colon Cleansing
Safety and Efficacy of OsmoPrep® Tablets Versus HalfLytely® and Bisacodyl Tablet Bowel Prep Kit for Colon Cleansing
The purpose of this study is to compare the safety and efficacy of OsmoPrep tablets versus HalfLytely and Bisacodyl Tablet Bowel Prep Kit in subjects who are undergoing colonoscopy.
- Trial name
- NCT01427296
- Testing
- Polyethylene glycol, Oral sodium phosphate solution
- Where
- 18 sites in United States
- Volunteers
- 2,154 people
- Sponsor
- Bausch Health Americas, Inc.
Need for Bowel Preparation
Efficacy and Safety of Prepopik® in Children for Overall Colon Cleansing in Preparation for Colonoscopy
To study the efficacy and safety of Prepopik® in children aged 9 to 16 years for overall colon cleansing in preparation of colonoscopy
- Trial name
- Prepopik PREA (NCT01928862)
- Testing
- Prepopik® ½ Sachet x 2 (9-12 years), Prepopik® 1 Sachet x 2 (9-12 years), Oral polyethylene glycol (PEG) based preparation (9-12 years)
- Where
- 9 sites in United States
- Volunteers
- 78 people
- Sponsor
- Ferring Pharmaceuticals
Sedation
A Dose-ranging Study to Evaluate the Safety and Efficacy of LUSEDRA (Fospropofol Disodium) as an Intravenous Sedative for Diagnostic or Therapeutic Colonoscopy in Adult Special Populations
The purpose of this study is to evaluate the safety and efficacy of LUSEDRA (fospropofol disodium) and to determine whether a dose lower than currently approved can provide effective moderate sedation required to complete…
- Trial name
- NCT01127438
- Testing
- fospropofol disodium Subgroup 1 Lower Dose, fospropofol disodium Subgroup 1 Approved Dose, fospropofol disodium Subgroup 2 Lower Dose
- Where
- 23 sites in United States
- Volunteers
- 153 people
- Sponsor
- Eisai Inc.
Colon Polyp
Collecting Recorded Videos of Colonoscopy Tests
The study shall mainly help to better evaluate the performance the APDS device and secondly it may help to assess the potential of the future alpha version of the device to be a useful and effective for the detection of colon…
- Trial name
- NCT03937063
- Testing
- Collecting recorded videos of Colonoscopy screening tests
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Magentiq Eye LTD
Colorectal Polyps
Metatranscriptomic Markers of Colonic Neoplasia
This study is a collaboration between Viome Life Sciences and Scripps Research Institute to develop and validate a noninvasive molecular diagnostic test for the detection of colorectal polyps.
- Trial name
- NCT07786818
- Testing
- This is an observational study that has no interventions
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Viome
Colonoscopy
Study 302: BLI4900 Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy
The purpose of this study is to compare the safety and efficacy of BLI4900 bowel preparation to an FDA-approved control as 2-day, split-dose bowel preparations prior to colonoscopy in adult patients.
- Trial name
- NCT04446312
- Testing
- Bowel Prep
- Where
- 34 sites in United States
- Volunteers
- 500 people
- Sponsor
- Braintree Laboratories
Colon Staining in Preparation for Colonoscopy
Colon Staining Efficacy of Single Oral Doses of Methylene Blue MMX
To describe and evaluate the mucosal staining efficacy of Methylene Blue MMX® tablets after total oral doses of 150 or 200 mg in patients undergoing a full colonoscopy for various reasons.
- Trial name
- CRO-11-108 (NCT03287219)
- Testing
- Methylene Blue MMX 25 mg modified release tablets
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Cosmo Technologies Ltd
Colonoscopy Procedure
Evaluation of the Performance of the Motus Cleansing System
The purpose of this study is evaluate the Motus GI Colon Cleansing system performance.
- Trial name
- MSC (NCT02161536)
- Testing
- Motus Cleansing System
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Clostridium Difficile Infection Recurrence
A Multi-center, Single-arm Trial Exploring the Safety and Clinical Effectiveness of RBX2660 Administered by Colonoscopy to Adults With Recurrent Clostridioides Difficile Infection
This trial will be initiated to explore whether RBX2660 (REBYOTA®) could be suitable for administration by the practice of colonoscopy.
- Trial name
- CDI-SCOPE (NCT05831189)
- Testing
- RBX2660
- Where
- 12 sites in United States
- Volunteers
- 41 people
- Sponsor
- Ferring Pharmaceuticals
Colonoscopy, Incomplete Colonoscopy
Endorail in Long Lasting Colonoscopy
Patients with long lasting colonoscopy are characterized by higher risk of incompletion. Endorail is an accessory for colonoscopy aimed at facilitating progression of the endoscope in the large intestine.
- Trial name
- NCT05626738
- Testing
- ENDORAIL
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 38 people
- Sponsor
- Endostart srl
Colonoscopy
Study to Investigate the Safety and Efficacy of 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy
This is a phase II, two-part, multiple-dose, dose-finding, single-blind study in adult participants undergoing elective colonoscopy for screening or diagnostic purposes.
- Trial name
- ABP-700 (NCT02800590)
- Testing
- ABP-700
- Where
- 3 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- The Medicines Company