Clinical trials: Colonoscopy Procedures
Preparation for Colonoscopy
Gatorade/Miralax With or Without Bisacodyl Versus NuLytely for Colonoscopy Preparation
The purpose of this study is to compare Nulytely (or Trilyte) with a Gatorade and Miralax combination for cleaning out the colon before colonoscopy.
- Trial name
- NCT01063049
- Testing
- Gatorade/Miralax, NuLytely, Bisacodyl
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gastroenterology Services, Ltd.
Anxiety and Fear
A Comparison Between Dexmedetomidine and Propofol-fentanyl Infusions for Sedation for Colonoscopy Procedures
Background: Different intravenous sedative drugs have been utilized for colonoscopy, with many anesthetists for painless sedation or monitored anesthesia care.
- Trial name
- NCT06148103
- Testing
- Patients who received Dexmedetomodine, patients who received propofol-fentanyl
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zulekha Hospitals
Adenoma Colon
Effect of Simethicone on Screening Colonoscopy
This study is evaluating the effect of adding a high dose of simethicone to the standard polyethylene glycol preparation for screening colonoscopy in the quality of the preparation , adenoma detection rate and withdrawal times.
- Trial name
- NCT03119168
- Testing
- Simethicone Solution, Polyethylenglycol
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Colonic Polyp, Colon Adenoma
Feasibility Study of a Novel Single Use Robotic Colonoscopy System
This is a single centre, non-randomized, tandem colonoscopy trial of the NISInspire-C System, followed immediately by a conventional colonoscope (CC).
- Conditions
- Colonic Polyp, Colon Adenoma, Colorectal Cancer
- Trial name
- NCT03979690
- Testing
- NISInspire-C System
- Where
- Hong Kong
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bio-Medical Engineering (HK) Limited
Education
A Validation Study of a Computerized Movement Analysis of the Colonoscope in Simulated Colonoscopy
A cross validation study comparing an international acknowledged assessment tool "Endoscopy Training System" (ETS) and movement analysis of the colonoscope based on raw data from coils within the scope.
- Trial name
- 3D-CoPS (NCT03401723)
- Testing
- 3D-Colonoscopy Progression Score, Endoscopy Training System, 3D-Colonoscopy Retraction Score
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Colonic Polyps
Evaluation of Computer-assisted, Non-cathartic CT Colonography
The purpose of this study is to evaluate the performance of a non-cathartic, computer-assisted form of CT Colonography (Virtual Colonoscopy) for detection of pre-cancerous colon polyps in a group of asymptomatic screening…
- Trial name
- ncCTC (NCT01200303)
- Testing
- non-cathartic CTC
- Where
- 3 sites in United States
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Colorectal Neoplasms
Impact of Experience on Results With the Third Eye Retroscope
The Third Eye Retroscope is a device that can be used with a colonoscope to improve the ability of a physician to see areas of the colon that may be hidden from the view of the colonoscope.
- Trial name
- NCT00969124
- Testing
- Third Eye Retroscope
- Where
- 9 sites in United States
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Avantis Medical Systems
Colorectal Cancer Screening
Comparison of Transparent Retractable Extension Device and Narrow Band Imaging on Colorectal Adenoma Detection
The investigators previously reported that colonoscopy with a transparent retractable extension (TRE) device improved the adenoma detection rate without affecting intubation and withdrawal times.
- Trial name
- NCT00765180
- Testing
- TRE vs. NBI
- Where
- Japan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Showa Inan General Hospital
Colorectal Cancer, Colorectal Polyp
Accuracy for Predicting Deep Submucosal Invasion
The main aim of this study is to determine whether the assessment of the invasive pattern based on NBI with dual focus/magnification or BLI with magnification ± chromoendoscopy (NBI+CE) for predicting deep invasion is…
- Trial name
- NBIBLI (NCT03748667)
- Testing
- White light endoscopy (WLE), NBI/BLI +/- chromoendoscopy (NBIBLI +/- CE)
- Where
- 14 sites in United States, Japan and 1 more
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Colorectal Cancer
Mailed FIT-Based Outreach Interventions
Colorectal cancer (CRC) is the second most common cancer and the second leading cause of cancer-related mortality in Singapore. Although annual fecal immunochemical testing (FIT) and periodic colonoscopy are recommended for…
- Trial name
- NCT07852793
- Testing
- SMS Reminders, SMS reminders + mailed reminder, SMS reminders + mailed reminder + patient navigation
- Where
- 5 sites in Singapore
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- National Cancer Centre, Singapore
Colonoscopy
The Effect of Virtual Reality Application on Pain, Anxiety, and Embarrassment During Colonoscopy
This study will be conducted to determine the effects of virtual reality (VR) intervention applied during colonoscopy performed without sedation on pain, anxiety, embarrassment, and physiological parameters.
- Trial name
- COLONOSCOPY (NCT07853300)
- Testing
- Virtual Reality (VR) Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Colonoscopy
A Low-residue Diet vs Clear Liquid Diet as a Bowel Colonoscopy Preparation With Polyethylene Glycol (PEG)
This was a randomized, endoscopists' blinded comparison of bowel colonoscopy cleansing and tolerability of a prespecified low-residue diet compared with a clear liquid diet and Polyethylene Glycol bowel preparation.
- Trial name
- PEG (NCT03358537)
- Testing
- Clear Liquid Diet, Low-residue Diet
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Diabetes Mellitus, Type 2, Sedoanalgesia
The Effect of Diabetes Mellitus in Colonoscopy Under Sedoanalgesia
INTRODUCTION AND AIM Diabetes Mellitus (DM) is a common endocrine disease in the world. Colon polyps and colorectal cancers are reported more in DM patients.
- Trial name
- NCT04477694
- Testing
- colonoscopy under sedoanalgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baskent University
Colorectal Cancer
Motivational Interviewing for Colonoscopy
The purpose of this study is to begin to examine the efficacy of a motivational interviewing intervention to increase African Americans' screening colonoscopy rates.
- Trial name
- NCT01877096
- Testing
- Motivational Interviewing, Attention Control
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Colonic Polyps
Effect of Single Colonoscopy on Colorectal Adenomas Detection
Individualized colonoscopy withdrawal time is determined based on the different grade of physician experience and quality of bowel preparation.
- Trial name
- NCT02693886
- Testing
- doctor experience
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Wuxi People's Hospital
Colonoscopy Preparation
2 Regimens of Lactulose for Colonoscopy Preparation in Adults
The purpose of the study is to determine the efficacy of 2 regimens of lactulose as a preparation for colonoscopy.
- Trial name
- NCT01887470
- Testing
- Full dose preparation, Split dose preparation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Cumberland Pharmaceuticals
Colon Cancer
Colonoscopy Motivation for Patients With Positive Immunochemical Fecal Test
Patients with an immunochemical fecal test positive, have to undergo a colonoscopy. Around 10% doesn't realize the colonoscopy. This study evaluate the impact of a motivational phone call (given by a doctor) to improve…
- Trial name
- Colofit+ (NCT03276091)
- Testing
- Colofit+ intervention
- Where
- France
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Patricia Soler-Michel
Colorectal Cancer Screening, Colon Polyps and Adenomas
Artificial Intelligence (AI) Technology May Help Patients to Understand Bowel Preparation Better Before They go for Colonoscopy.This Study Attempts to Leverage AI Chatbot in Counselling Patients to Improve Bowel Cleanliness, Reduce Anxiety as Well as Increase Procedural Satisfaction
Traditional pre-colonoscopy counselling requires significant time from healthcare workers to explain procedures, limiting efficiency and patient turnover.
- Conditions
- Colorectal Cancer Screening, Colon Polyps and Adenomas, Bowel Preparation Quality, Artificial Intelligence (AI)
- Trial name
- NCT06905782
- Testing
- AI chatbot study arm, Traditional counselling study arm
- Where
- Malaysia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Colorectal Neoplasms
Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)
Adenoma detection rate (ADR) is a quality indicator of colonoscopy performed for colorectal cancer screening. Population studies have shown that traditional air colonoscopy fails to eliminate post screening colonoscopy cancers or…
- Trial name
- NCT01607255
- Testing
- Indigo carmine, water (exchange) method, water (exchange) plus dye method
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Colorectal Cancer Screening
Study of Using Computerized Education to Increase Patients' Confidence in Their Ability to Be Screened for Colon Cancer
The purpose of this study is to determine whether a newly developed educational software program is effective in increasing patients' confidence in their ability to undergo colon cancer screening.
- Trial name
- NCT00273585
- Testing
- Personally-tailored educational software program
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, Davis