Clinical trials: Colonoscopy Procedures
Bowel Preparation Scale, Adenoma Detection Rate
Effect of Gum Chewing on Bowel Cleansing Before Colonoscopy
In this randomized controlled study, consecutive outpatients scheduled for elective colonoscopy were randomized into two groups. Group A patients (n = 150) used 2 L PEG before colonoscopy.
- Trial name
- NCT02507037
- Testing
- gum+PEG, polyethylene glycol
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colonic Adenomas
Comparison Between White Light Endoscopy and Bright Narrow Band Imaging in Diagnosis Colonic Adenomas.
Removal of colorectal adenomas prevents the occurence of colorectal cancers. The use of chromo-endoscopy has been shown to improve the detection of flat adenomas.
- Trial name
- WLEvB-NBI (NCT01737567)
- Testing
- Bright Narrow Band Imaging., White Light Endoscopy
- Where
- Australia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Professor Michael Bourke
Digestive System Diseases, Colonoscopy Sedation
Non-anesthesiologist Administered Propofol Sedation for Colonoscopy - a Randomized Clinical Trial
Propofol is the preferred sedation for colonoscopy. There is debate on the safety of the administration of propofol by non-anesthesiologists, despite moderate quality evidence that support its' use.
- Trial name
- NCT02067065
- Testing
- Non-anesthesiologist propofol sedation, Propofol sedation administered by an anesthesiologist, Colonoscopy
- Where
- Portugal
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Hospital Beatriz Ângelo
Colorectal Cancer, Polyp
Performance Evaluation of the NaviAid™ G-Eye System
The purpose of this study is to compare the additional diagnostic yield obtained by performing NaviAid™ G-Eye procedure vs. the diagnostic yield obtained by performing standard colonoscopy procedure.
- Conditions
- Colorectal Cancer, Polyp, Adenoma
- Trial name
- NCT01552200
- Testing
- Group A-Standard Colonoscopy, then NaviAid™ G-Eye procedure, Group B-NaviAid™ G-Eye procedure, then Standard Colonoscopy
- Where
- 4 sites in Germany, Israel
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Colonoscopy
The Effect of Virtual Reality Application on Pain, Anxiety, and Embarrassment During Colonoscopy
This study will be conducted to determine the effects of virtual reality (VR) intervention applied during colonoscopy performed without sedation on pain, anxiety, embarrassment, and physiological parameters.
- Trial name
- COLONOSCOPY (NCT07853300)
- Testing
- Virtual Reality (VR) Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Colon Staining in Preparation for Colonoscopy
Colon Staining Efficacy of Single Oral Doses of Methylene Blue MMX
To describe and evaluate the mucosal staining efficacy of Methylene Blue MMX® tablets after total oral doses of 150 or 200 mg in patients undergoing a full colonoscopy for various reasons.
- Trial name
- CRO-11-108 (NCT03287219)
- Testing
- Methylene Blue MMX 25 mg modified release tablets
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Cosmo Technologies Ltd
Colonoscopy Procedure
Evaluation of the Performance of the Motus Cleansing System
The purpose of this study is evaluate the Motus GI Colon Cleansing system performance.
- Trial name
- MSC (NCT02161536)
- Testing
- Motus Cleansing System
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Colon Cancer
Latino Peers as Patient Navigators for Colon Cancer Screening
Disparities among racial and ethnic minorities remain prevalent despite advances in medical science that make thes early detection and prevention of colorectal cancer a possibility for all human kind.
- Trial name
- NCT02226107
- Testing
- Peer-PN, Pro-PN
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Quality of Bowel Preparation
Effect of Simethicone on Colon Preparation During Water Exchange Colonoscopy
Background: Colonoscopy reduces colorectal cancer mortality by enabling early detection and removal of adenomas. Its effectiveness, however, depends heavily on bowel preparation quality and mucosal visibility.
- Trial name
- NCT07674160
- Testing
- Simethicone with PEG, PEG
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Bowel Preparation Quality
Can Artificial Intelligence Reduce Consumption of Standard High Volume Bowel Preparation Regimen Among Older Population, Without Compromising the Quality of Colonoscopy? An International Multi-centre Randomized Controlled Trial.
The goal of this study is to assess the clinical and cost-effectiveness of the AI bowel preparation evaluation system in reducing the consumption volume of the standard high-volume PEG regimen before colonoscopy among the older…
- Trial name
- AIBP (NCT06904209)
- Testing
- AI
- Where
- Hong Kong
- Volunteers
- 1,824 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colon Cancer
Cruciferous Vegetable Intake and Histone Status in Screening Colonoscopy Patients
This research study will assess cruciferous vegetable intake in patients presenting for screening colonoscopy and correlate intake with histone status and histone deacetylace (HDAC) expression in tissue biopsy specimens and…
- Trial name
- NCT01344330
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Colonoscopy
A Pre-endoscopic Prediction Model for Inadequate Bowel Preparation in Patients Receiving Split Dose Polyethylene Glycol Preparation
After written consent for participating in clinical research studies, all clinical studies conducted to in the one day. The investigators will ask and record about bowel cleansing state in all patients who performed colonoscopy.
- Trial name
- NCT02174601
- Where
- South Korea
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Adenoma
The Effect of Segmental Re-examination of Colon for Adenoma Detection in Colonoscopy
The aim of this study was to determine whether segmental re-examination of the each segment (right colon, mid-colon, and left colon) could increase the proximal adenoma detection rate (ADR) and to evaluate the time-effectiveness…
- Trial name
- NCT03268200
- Testing
- segmental reexamination
- Where
- South Korea
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Ottawa Score, Adenoma
A Repeated Instruction by Telephone on the Day Before Colonoscopy to Patients Undergoing Colonoscopy
Cell phone retell the instruction of bowel preparation on the day before colonoscopy would help patient to prepare for colonoscopy and improve the quality of the bowel preparation.
- Trial name
- NCT01584817
- Testing
- telephone education
- Where
- China
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Colonoscopy
Usefulness Of Flospan As A Premedication For Colonoscopy
Usefulness of Flospan as a premedication for colonoscopy: A randomized double-blind controlled trial
- Trial name
- NCT01842932
- Testing
- Phloroglucin, Cimetropium bromide, Colonoscopy
- Where
- South Korea
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Ajou University School of Medicine
Colo-rectal Cancer, Polyp of Colon
Evaluation of Cold Forcep and Cold Snare Polypectomy for Polyps Less Than or Equal to 3mm in Size During Colonoscopy
The focus of the study is to evaluate impact of cold forcep and cold snare in achieving complete resection during polypectomy of polyps <=3mm during colonoscopy.
- Conditions
- Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyp of Colon
- Trial name
- NCT04551001
- Testing
- Cold forcep polypectomy, Cold snare polypectomy
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Stanford University
Colonic Polyps
Effect of Single Colonoscopy on Colorectal Adenomas Detection
Individualized colonoscopy withdrawal time is determined based on the different grade of physician experience and quality of bowel preparation.
- Trial name
- NCT02693886
- Testing
- doctor experience
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Wuxi People's Hospital
Colorectal Cancer Screening
Colon Capsule Endoscopy (CCE) Versus Computed Tomographic Colonography (CTC) in the Identification of Colonic Polyps in a Screening Population.
The primary objective of this multicenter, prospective, randomized study is to assess the diagnostic yield of Colon Capsule Endoscopy (CCE) versus Computed Tomographic Colonography (CTC) in a screening population.
- Trial name
- TOPAZ (NCT02754661)
- Testing
- COLON Capsule endoscopy, Computed Tomographic Colonography
- Where
- 13 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Colonoscopy, Safety Issues
Motorized Spiral Colonoscopy Trial: A First Feasibility Trial
The aim of this study is to assess the feasibility and the safety of the Novel Motorized Spiral Endoscope to examine the colon. The study is conceived as proof of concept trial with the primary aim to achieve a cecal intubation…
- Conditions
- Colonoscopy, Safety Issues, Adenoma
- Trial name
- MSCT (NCT03000361)
- Testing
- Motorized Spiral Colonoscopy
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Evangelisches Krankenhaus Düsseldorf
Adenoma, Colonoscopy
Effect of Two Colonoscopy AI Systems for Colon Polyp Detection
Computer-aided detection (CADe) systems have been actively researched for polyp detection in colonoscopy. The investigators aim to identify the effect of two CADe systems according to the system performance on false positive rate
- Conditions
- Adenoma, Colonoscopy, Sessile Serrated Adenoma
- Trial name
- NCT05089071
- Testing
- Assist by artificial intelligence system for colon polyp detection
- Where
- South Korea
- Volunteers
- 3,046 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital