Clinical trials: Colonoscopy Procedures
Adenoma Detection Rate
Comparison of Newer Colonoscopy Devices With Standard Forward Viewing (SFV) Colonoscopes in Daily Practice
Retrospective data analysis of comparsion of 3 types of colonoscopes in daily practice (FUSE Full spectrum colonoscopy with 330° angle of view vs Pentax standard HD-colonoscopes and Pentax plus Endocuff): medical device of the…
- Trial name
- NCT04472741
- Testing
- difference between colonoscopes
- Volunteers
- 4,114 people, healthy volunteers welcome
- Sponsor
- Gastroenterologie Baden-Wettingen
Enhancement of the ADR During Colonoscopy
Use of Peppermint Oil During Screening Colonoscopy to Improve Visibility
The investigators hypothesize that spraying peppermint oil containing L-menthol onto the colonic mucosa during colonoscopy will relax smooth muscle allowing better colonic visualization.
- Trial name
- NCT03286764
- Testing
- Peppermint Oil, Distilled water
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colorectal Cancer
I-Scan Vs High Definition White Light (Main Study)
The purpose of this study is to assess whether the use of I-Scan during colonoscopy leads to an increased yield of adenomas in the colon among a population at increased risk for CRC.
- Trial name
- NCT02016326
- Testing
- HD Colon, I-scan 1, I-Scan 2
- Where
- Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Colorectal Neoplasia, Colorectal Cancer
The Longterm Risk of Advanced Colorectal Neoplasia After Colonoscopy - A Population-based Cohort Study in Hong Kong
The primary objective of this study is to analyze the 15-year cumulative incidence of advanced colorectal neoplasia and CRC-related mortality after the index colonoscopy.
- Trial name
- ACNC (NCT04815525)
- Where
- Hong Kong
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colonoscopy [E01.370.372.250.250.200]
Comparison of Low-volume PEG Plus Ascorbic Acid Versus Standard PEG Solution as Bowel Cleansing for Colonoscopy
The purpose of this study is to compare two regimens of low volume (2L) polyethylene glycol(PEG)plus ascorbic acid versus standard volume (4L) PEG alone for bowel preparation in out-patients
- Trial name
- NCT01740518
- Testing
- polyethylene glycol, ascorbic acid
- Where
- South Korea
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Dong Il Park, M.D, Ph.D.
Minimally Sedated Patient Undergoing Colonoscopy
Comparing Maximal and Half-maximal Suction Pressure Applied During Water Exchange in Colonoscopy
This prospective, randomize, controlled trial will compared maximal to half-maximal suction pressure applied during water exchange in patients undergoing minimally sedated colonoscopy.
- Trial name
- NCT01948284
- Testing
- half-maximal pressure, maximal pressure, Suction Unit
- Where
- Taiwan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Colorectal Cancer, Colorectal Adenomas
Water Exchange Versus Carbon Dioxide for Colonoscopy
Colonoscopy is commonly used in screening for colorectal cancer. A refined technique of colonoscopy involving the use of water as the sole modality to aid colonoscope insertion, water exchange, has been described in recent…
- Conditions
- Colorectal Cancer, Colorectal Adenomas, Colorectal Polyps, Pain
- Trial name
- NCT01633333
- Testing
- Water exchange colonoscopy, Carbon dioxide insufflation
- Where
- 3 sites in Norway, Poland
- Volunteers
- 473 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Misadventure During Endoscopic Examination
Effects of VR and Mural Curtain During Colonoscopy
Background: Today, colonoscopy is widely used in many diseases, especially in the screening and diagnosis of colorectal cancers.
- Trial name
- VR_COLON (NCT05410184)
- Testing
- Virtual Reality Glasses group, mural curtain group
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Colon Cancer, Cancer Colorectal
IMProving Adherence to Colonoscopy Through Teams and Technology
Complete and timely colonoscopy after an abnormal stool-based colorectal cancer screening test results in early detection, cancer prevention, and reduction in mortality, but follow-up in safety-net health systems occurs in less…
- Conditions
- Colon Cancer, Cancer Colorectal, Colorectal Cancer
- Trial name
- IMPACTT (NCT06191185)
- Testing
- BPB, No PIN, BPB, PIN, No BPB, PIN
- Where
- United States
- Volunteers
- 1,418 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Colonic Transendoscopic Enteral Tubing
Methods of Colonic Transendoscopic Enteral Tubing
Colonic transendoscopic enteral tubing (TET) is a novel, safe, convenient, and reliable way for fecal microbiota transplantation (FMT) and the whole-colon enema treatment.
- Trial name
- NCT03621033
- Testing
- colonic transendoscopic enteral tubing
- Where
- 2 sites in China
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Nanjing Medical University
Colorectal Cancer (CRC) Screening
A Novel Multi-functional Artificial Intelligence System on Treatment Efficacy and Implementation in Colonoscopy
To overcome non-neoplastic polyp (NNP) resections, computer-aided diagnosis (CADx) systems have been developed. In a meta-analysis, the performance of CADx systems was superior to endoscopists.
- Trial name
- mAInstream (NCT07844252)
- Testing
- CADe/CADx
- Volunteers
- 2,818 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Cancer, Screening
ColoAssist vs. MEI
Colonoscopy aims to investigate the entire colon by advancing the colonoscope tip from the rectum to the cecum, a process called cecal intubation.
- Trial name
- NCT01895504
- Testing
- ColoAssist, MEI
- Where
- 2 sites in Norway
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Colorectal Neoplasms
Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)
Adenoma detection rate (ADR) is a quality indicator of colonoscopy performed for colorectal cancer screening. Population studies have shown that traditional air colonoscopy fails to eliminate post screening colonoscopy cancers or…
- Trial name
- NCT01607255
- Testing
- Indigo carmine, water (exchange) method, water (exchange) plus dye method
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Colorectal Cancer
Clear Liquid vs Liberalized Diet in Preparation for Colonoscopy
Colorectal cancer is the third most common cancer diagnosed in both men and women in the United States. The death rate from this disease, however, has been decreasing over the last 20 years.
- Trial name
- NCT02621658
- Testing
- Clear Liquid Diet, Full Liquid Diet
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- San Antonio Military Medical Center
Advanced Colorectal Cancer, Colo-rectal Cancer
Optimal Surveillance Strategy After Positive FIT and Negative Colonoscopy
Individuals with high fecal hemoglobin concentrations detected by fecal immunochemical testing (FIT) but negative findings on high-quality colonoscopy represent a clinically challenging population.
- Conditions
- Advanced Colorectal Cancer, Colo-rectal Cancer, Fecal Immunochemical Test
- Trial name
- NCT07470658
- Testing
- Colonoscopy Surveillance
- Where
- Taiwan
- Volunteers
- 1,274 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Colonoscopy, Gastrointestinal Microbiome
Effect of Carbon Dioxide Insufflation and Appendix on the Restoration of Intestinal Microecology After Colonoscopy.
The goal of this observational study is to learn about Influencing factors of intestinal microecological changes before and after colonoscopy.
- Conditions
- Colonoscopy, Gastrointestinal Microbiome, Appendix, Carbon Dioxide Insufflation
- Trial name
- NCT05637021
- Testing
- Carbon dioxide insufflated during colonoscopy
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Zhongshan Hospital Xiamen University
Polyp, Adenomatous Polyp
Endoscopy Nurse Participation in Adenoma Detection Rate During Colonoscopy
Colorectal cancer (CRC) is the second most common cancer and the fourth leading cause of cancer death in Korea. Colonoscopy with polypectomy decreases the incidence and mortality from colorectal cancer.
- Conditions
- Polyp, Adenomatous Polyp, Colonoscopy
- Trial name
- NCT01124266
- Testing
- standard of care colonoscopy
- Where
- 6 sites in South Korea
- Volunteers
- 844 people, healthy volunteers welcome
- Sponsor
- Soon Chun Hyang University
Healthy
The Effect of Post Colonoscopy Abdominal Massage on Abdominal Pain, Distension, Discomfort and Patient Satisfaction
Background: Abdominal pain, distension, and discomfort are the most frequently seen side effects after colonoscopy. These side effects can cause physical and mental results and increased workloads and care costs.
- Trial name
- NCT04979351
- Testing
- Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Procedure Time
Combined Simultaneous EGD-colonoscopy Trial (CoSi Endoscopy)
The COVID -19 pandemic has reduced endoscopy services to an average of 83% producing a significant economic impact on endoscopy units worldwide.
- Trial name
- NCT04473456
- Testing
- Simultaneous EGD and colonoscopy
- Where
- Colombia
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- EmuraCenter LatinoAmerica
Predictive Cancer Model
Innovative Approach to Detect Recurrent Colorectal Lesions With Surveillance Via Mutation Analysis & Clinical Phenotype
It is known that the development of colorectal adenoma is dependent on the appearance of somatic mutations in protooncogenes and tumor suppressor genes.
- Trial name
- MTG (NCT05929365)
- Testing
- colonoscopy
- Where
- Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Military University Hospital, Prague