Clinical trials: Colonoscopy Procedures
Colon Cleansing in Preparation for Colonoscopy
A Phase III Study With FE 999169 Versus Niflec for Colon Cleansing
To demonstrate non inferiority of a) "FE 999169 Split Dosing Schedule" (one dose on the day before and the second dose on the day of colonoscopy) and b) "FE 999169 Day Before Dosing Schedule" (two doses on the day before…
- Trial name
- NCT02215954
- Testing
- FE 999169, Niflec
- Where
- 4 sites in Japan
- Volunteers
- 637 people
- Sponsor
- Ferring Pharmaceuticals
Unsedated Colonoscopy, Water Exchange Colonoscopy
Prospective RCT Of Water Exchange (WE) vs. WE Plus Cap-Assisted Colonoscopy
This is a study to compare two different, but normally, used methods of colonoscopy in patients undergoing colonoscopy without sedation.
- Conditions
- Unsedated Colonoscopy, Water Exchange Colonoscopy, Cap, Colonoscopy Pain
- Trial name
- NCT03160859
- Testing
- Control, Study method
- Where
- 3 sites in United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Colon Cancer, Rectal Cancer
Compare Propofol to Fentanyl and Midazolam for Colonoscopy
The study aim is to determine if Propofol or the combination of Fentanyl and low-dose Midazolam, are equivalent for patient satisfaction and discomfort when undergoing a colonoscopy. This is a prospective randomized study of 262.
- Conditions
- Colon Cancer, Rectal Cancer, Colonic Diverticulosis
- Trial name
- NCT01488045
- Testing
- Fentanyl, Propofol, Midazolam
- Where
- United States
- Volunteers
- 289 people
- Sponsor
- Trinity Health Michigan
Bowel Preparation Solutions
Comparison of Clenpiq vs Golytely Bowel Preparation
This is a prospective randomized study which will be done at main campus Cleveland Clinic. The investigators will be comparing the colon cleansing by the Boston Bowel Preparation Scale in participants undergoing colonoscopy as an…
- Trial name
- NCT03198221
- Testing
- Golytely, Clenpiq
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The Cleveland Clinic
Colorectal Cancer Screening
Bowel Preparation in Colonoscopy: Lactulose vs Polyethyleneglycol, Randomized Double-blind Comparative Clinical Trial, Multicenter Study.
The goal of this clinical trial it is to bowel the instestinal preparation with lactulose vs poliethylenglicol as better agent to have a quality colonoscopy and demostrate that lactulose is most efective, has a good tolerance and…
- Trial name
- NCT06666556
- Testing
- Bowel preparation before colonoscopy
- Where
- 3 sites in Mexico
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- Hospital Civil de Guadalajara
Colorectal Cancer
Translation of Colorectal Cancer Screening Guidelines to Practice: A System Intervention
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States. Results from randomized clinical trials and intervention studies have suggested that implementation of a CRC screening program for…
- Trial name
- NCT00122187
- Testing
- Electronic Consult System
- Where
- 9 sites in United States
- Volunteers
- 8 people
- Sponsor
- US Department of Veterans Affairs
Elective Colonoscopy
Efficacy and Safety of mAnnitol in Bowel Preparation During Elective Colonoscopy and Comparison With Moviprep®
The purpose of this dose finding/comparative efficacy study is to first single out the most appropriate dose of mannitol for bowel preparation (phase II) and, subsequently, demonstrate the non-inferiority of the efficacy of…
- Trial name
- SATISFACTION (NCT04759885)
- Testing
- Phase II: NTC015 low dose, Phase II: NTC015 medium dose, Phase II: NTC015 high dose
- Where
- 35 sites in France, Germany and 2 more
- Volunteers
- 886 people
- Sponsor
- NTC srl
Colorectal Cancer Screening
Colon Capsule Endoscopy (CCE) Versus Computed Tomographic Colonography (CTC) in the Identification of Colonic Polyps in a Screening Population.
The primary objective of this multicenter, prospective, randomized study is to assess the diagnostic yield of Colon Capsule Endoscopy (CCE) versus Computed Tomographic Colonography (CTC) in a screening population.
- Trial name
- TOPAZ (NCT02754661)
- Testing
- COLON Capsule endoscopy, Computed Tomographic Colonography
- Where
- 13 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Right Colon Adenoma Miss Rate, Right Colon Hyperplastic Polyp Miss Rate
Right Colon Polyp Miss Rates of Water Exchange and Carbon Dioxide Insufflation Colonoscopy
This will be a prospective randomized controlled trial comparing CO2 insufflation and WE in terms of right colon combined adenoma miss rate (AMR) and hyperplastic polyp miss rate (HPMR) by tandem inspection.
- Trial name
- NCT03845933
- Testing
- Colon polypectomy
- Where
- Taiwan
- Volunteers
- 262 people
- Sponsor
- Evergreen General Hospital, Taiwan
Colonoscopy, Endoscopy, Digestive System
Safety and Effectiveness of a Computer-Assisted Personalized Sedation (CAPS) Device for Propofol Delivery During Endoscopy
Patients routinely receive sedation during a colonoscopy or upper endoscopy (esophagogastroduodenoscopy; EGD) procedure. Propofol is a sedative that can be used during these procedures.
- Conditions
- Colonoscopy, Endoscopy, Digestive System, Conscious Sedation
- Trial name
- NCT00452426
- Testing
- Computer-Assisted Personalized Sedation (CAPS) Device (SEDASYS® System), benzodiazepines and opioid sedation
- Where
- 7 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Ethicon Endo-Surgery
Colonoscopy, Bowel Preparation
BLI800-480: A Safety and Efficacy Evaluation of 2 Different Bowel Cleansing Preparations in Adult Subjects
To compare the safety, tolerance and efficacy of SUPREP Bowel Prep Kit to an FDA approved control as bowel preparations prior to colonoscopy in adult patients.
- Conditions
- Colonoscopy, Bowel Preparation, Endoscopy
- Trial name
- NCT01786629
- Testing
- SUPREP Bowel Prep Kit, FDA approved bowel preparation containing electrolytes
- Where
- 10 sites in United States
- Volunteers
- 338 people
- Sponsor
- Braintree Laboratories
Desaturation of Blood, Obesity
High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients
It is standard practice in the United States and many parts of world to perform Gastrointestinal (GI) endoscopy with the patient under deep sedation.
- Conditions
- Desaturation of Blood, Obesity, Colonoscopy, Sleep Apnea
- Trial name
- NCT03148262
- Testing
- The Comfort Flo system, The Salter nasal cannula
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- University of Texas Southwestern Medical Center
CRC
Evaluation of the Motus GI CleanUp System During Screening Colonoscopy
Motus GI is developing a single-use device that attaches to a standard colonoscope, thereby integrating colon cleansing, screening and treatment into one procedure. The device creates turbulence within the colon using water jets.
- Trial name
- NCT01838980
- Testing
- Motus GI Clean-Up Device
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Preparation for Colonoscopy
Gatorade/Miralax With or Without Bisacodyl Versus NuLytely for Colonoscopy Preparation
The purpose of this study is to compare Nulytely (or Trilyte) with a Gatorade and Miralax combination for cleaning out the colon before colonoscopy.
- Trial name
- NCT01063049
- Testing
- Gatorade/Miralax, NuLytely, Bisacodyl
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gastroenterology Services, Ltd.
Adenoma Colon
Effect of Simethicone on Screening Colonoscopy
This study is evaluating the effect of adding a high dose of simethicone to the standard polyethylene glycol preparation for screening colonoscopy in the quality of the preparation , adenoma detection rate and withdrawal times.
- Trial name
- NCT03119168
- Testing
- Simethicone Solution, Polyethylenglycol
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Colorectal Neoplasms
Impact of Experience on Results With the Third Eye Retroscope
The Third Eye Retroscope is a device that can be used with a colonoscope to improve the ability of a physician to see areas of the colon that may be hidden from the view of the colonoscope.
- Trial name
- NCT00969124
- Testing
- Third Eye Retroscope
- Where
- 9 sites in United States
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Avantis Medical Systems
Colonoscopy Preparation
2 Regimens of Lactulose for Colonoscopy Preparation in Adults
The purpose of the study is to determine the efficacy of 2 regimens of lactulose as a preparation for colonoscopy.
- Trial name
- NCT01887470
- Testing
- Full dose preparation, Split dose preparation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Cumberland Pharmaceuticals
Colorectal Neoplasms
Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)
Adenoma detection rate (ADR) is a quality indicator of colonoscopy performed for colorectal cancer screening. Population studies have shown that traditional air colonoscopy fails to eliminate post screening colonoscopy cancers or…
- Trial name
- NCT01607255
- Testing
- Indigo carmine, water (exchange) method, water (exchange) plus dye method
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Polyps
Cap-fitted Colonoscopy: a Randomized, Tandem Colonoscopy Study of Adenoma Miss Rates
This is a test in which a thin, black, flexible tube with a lighting system on the end is passed through the anus, into the rectum, in order to examine the large bowel or intestine, also called the colon.
- Trial name
- NCT00577083
- Testing
- Cap-fitted colonoscopy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colorectal Neoplasm, Colonic Polyps
Clinical Study of Real Time Colorectal Polyp Diagnosis During Colonoscopy - the VALID Colonoscopy Study
The investigators hypothesize that high definition colonoscopy with close focus narrow band imaging features has a high diagnostic accuracy for colorectal polyp histology, and can replace formal pathologic assessment in cases of…
- Trial name
- VALID (NCT01288833)
- Testing
- Close focus HD NBI Colonoscopy System
- Where
- 2 sites in United States
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System