Clinical trials: Colonoscopy Procedures
Colorectal Polyp, Colorectal Neoplasms
Colonoscopy vs Stool Testing for Older Adults With Colon Polyps
This is a multi-site comparative effectiveness randomized controlled trial (RCT) comparing annual fecal immunochemical testing (FIT) and colonoscopy for post-polypectomy surveillance among adults aged 65-82 with a history of…
- Conditions
- Colorectal Polyp, Colorectal Neoplasms, Colorectal Adenoma, Colorectal Cancer
- Trial name
- COOP (NCT05612347)
- Testing
- FIT, Colonoscopy
- Where
- 24 sites in United States, Canada
- Volunteers
- 6,434 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Colonoscopy, Colonic Polyps
Implementation of Optical Diagnosis for Diminutive Polyps Amongst Endoscopists: Training and Long-term Quality Assurance
In this study, Dutch gastroenterologists who are certified for performing colonoscopies on FIT-positive patients in the Dutch population screening program are trained in optical diagnosis with validated methods.
- Trial name
- DISCOUNT2 (NCT02407925)
- Testing
- Feedback
- Where
- 13 sites in Netherlands
- Volunteers
- 3,144 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Ulcerative Colitis
Tolerability and Efficacy of Sodium Picosulfate/Magnesium Citrate Versus PEG/Ascorbic Acid in Ulcerative Colitis Patients
Ulcerative colitis is a chronic condition that results in the inflammation of the colon and rectum. Patients suspected to have ulcerative colitis are diagnosed via colonoscopy.
- Trial name
- NCT03581149
- Testing
- Sodium Picosulfate/Magnesium Citrate Laxative, 2L polyethylene glycol/ascorbic acid
- Where
- Lebanon
- Volunteers
- 68 people
- Sponsor
- American University of Beirut Medical Center
Colonic Polyps, Adenomatous Polyps
Impact of Indigo Carmine Pump Spraying on the Adenoma Detection Rate
Detection and removal of polyps during colonoscopy is crucial for the prevention of colorectal cancer. Indigo carmine spraying up to the colonic mucosa could probably increase the adenoma detection rate.
- Conditions
- Colonic Polyps, Adenomatous Polyps, Adenoma Detection Rate, Chromoendoscopy
- Trial name
- NCT06596317
- Testing
- Chromoendoscopy, Conventional colonoscopy
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Shandong University
Bowel Preparation Quality, Colonoscopy
Bowel Preparation Quality Following Video-Based Intervention and Educational Booklet Versus Standard of Care in an Outpatient Setting
High cancellation rates and suboptimal bowel preparation increase patient discomfort, drive economic waste, and compromise clinical outcomes.
- Conditions
- Bowel Preparation Quality, Colonoscopy, Patient Education Materials
- Trial name
- PrepVibe (NCT07685652)
- Testing
- Verbal Counseling, Tri-lingual Educational Pamphlet, QR-Linked Instructional Videos
- Where
- Malaysia
- Volunteers
- 324 people
- Sponsor
- Sibu Hospital
Bowel Cleansing Prior to Colonoscopy
Study of Efficacy of Bowel Preparation Before Colonoscopy
The purpose of this study is to evaluate the effectiveness of FM-602 as a bowel preparation before colonoscopy.
- Trial name
- NCT00771485
- Testing
- FM-602, Marketed Bowel Cleanser
- Where
- 3 sites in United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- C.B. Fleet Company, Inc.
Colon Cancer
Cruciferous Vegetable Intake and Histone Status in Screening Colonoscopy Patients
This research study will assess cruciferous vegetable intake in patients presenting for screening colonoscopy and correlate intake with histone status and histone deacetylace (HDAC) expression in tissue biopsy specimens and…
- Trial name
- NCT01344330
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Colonic Polyp, Colon Cancer
Improving Outpatient Colonoscopy Bowel Prep With the Orton Score
Colonoscopy is a common endoscopic procedure which the UVA Gastroenterology \& Hepatology department performs on a daily basis for both screening/surveillance and diagnostic/therapeutic intent.
- Trial name
- NCT04093557
- Testing
- Orton Score, Typical Standard of Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia
Subjects Undergoing a Complete Exploratory Diagnostic Colonoscopy for the First Time.
Safety and Efficacy Study of CitraFleet (Sodium Picosulphate) as an Evacuating Treatment Prior to Colonoscopy.
The purpose of this study is to determine any significant differences in the efficacy and acceptability between CitraFleet and Klean Prep® (polyethylene glycol) for the preparation of gastrointestinal subjects undergoing a colon…
- Trial name
- NCT01065857
- Testing
- Sodium picosulphate, light magnesium oxide and anhydride citric acid., Polyethylene glycol, KCl, NaCl, sodium sulphate anhydrous and sodium bicarbonate.
- Where
- 15 sites in Spain
- Volunteers
- 547 people
- Sponsor
- Laboratorios Casen-Fleet S.L.U.
Ambulatory Patients Referred for a First-time Colonoscopy
Sedation Effect on the Global Quality Colonoscopy
This study aims to assess the impact of the use of sedation on the overall quality of the colonoscopy, therefore addressing each and every one of its dimensions, namely: scientific and technical quality, perceived quality and…
- Trial name
- NCT02220530
- Testing
- Conscious sedation with iv midazolam and fentanyl.
- Where
- Spain
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Hospital San Juan de Dios Tenerife
Colonoscopy, Colorectal Cancer Screening
Triton 1.5 Robotic System for Diagnostic Colonoscopy in the Middle East
The purpose of this study is to gain early experience in the Triton 1.5 System in performing diagnostic, screening, surveillance, and basic therapeutic tasks (e.g., polypectomy for lesions ≤ 2 cm).
- Trial name
- CARE-UAE (NCT07835542)
- Testing
- Diagnostic Test: Diagnostic Colonoscopy
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Colonoscopy
Comparing 4L Golytely to 2L Golytely With 15mg Bisacodyl Regimens for Inpatient Colonic Preparation
The investigators wish to compare the efficacy and patient tolerability of a preparation consisting of 2L Golytely (PEG + electrolytes) plus 15mg of bisacodyl vs the standard preparation of 4L Golytely.
- Trial name
- NCT01452737
- Testing
- Standard Bowel Prep, 2L Golytely/bisacodyl
- Where
- Canada
- Sponsor
- University of British Columbia
Outpatient Colonoscopy for Colorectal Cancer Screening or for Symptoms Suggestive of Colonic Diseases
Effect of Anesthesia on Force Application During Colonoscopy
The aim of the study is to determine if more force is used during colonoscopy when patients receive monitored anesthesia with propofol versus conscious sedation.
- Trial name
- CFM (NCT02101099)
- Testing
- Colonoscopy Force Monitor
- Where
- 3 sites in United States
- Volunteers
- 102 people
- Sponsor
- Artann Laboratories
Bowel Preparation, Colonoscopy
Low Volume PEG With Low Residue Test Meals Versus High Volume Split-dose PEG Bowel Preparation
Morning only low volume PEG with low reside meals may enhance patient tolerability and have similar bowel cleansing efficacy compared to standard method using high volume split-dose PEG with standard diet.
- Trial name
- LOWPEG (NCT01568814)
- Testing
- Low volume PEG, high volume PEG
- Where
- South Korea
- Volunteers
- 188 people
- Sponsor
- Inje University
Colonoscopy
Right or Left for Colonoscopy?
Colonoscopy is technically challenging. Conventionally, colonoscopy begins with patients positioned in the left lateral position.
- Trial name
- ROLCOL (NCT02305706)
- Testing
- starting position in colonoscopy
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Colorectal Cancer Screening, Bowel Cleansing for Colonoscopy
Cleansing Options in Out-Patient Setting to Improve Tolerance (COOP SIT) Trial
The purpose of this research is to compare patient preferences for two bowel preparation options: low-volume tablets (Suflave/Sutab) versus the standard colon preparation using Golytely (polyethylene glycol).
- Trial name
- COOP SIT (NCT07215000)
- Testing
- Golytely, Sulfave, Sutab
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
CRC Screening, CRC (Colorectal Cancer)
Improving Rates of Diagnostic Colonoscopy in Native Americans
Colorectal cancer (CRC) is the second-leading cause of cancer death in both men and women in the United States. Compared to national averages, Native Americans (NA) endure a disproportionate burden of CRC incidence and…
- Trial name
- YVONNE-DX (NCT07115875)
- Testing
- Digital Outreach, In Person consultation
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- University of Oklahoma
Colon Polyp
Combined Chromoendoscopy and Water Method for Screening Colonoscopy
In a RCT in screening colonoscopy subjects, we will determine if chromoendoscopy using a dilute solution of Indigocarmine (IC) delivered by the water method (study method) will improve adenoma detection rate compared with the…
- Trial name
- NCT01383265
- Testing
- Water method and chromoendoscopy, Water method
- Where
- United States
- Volunteers
- 1,177 people
- Sponsor
- VA Northern California Health Care System
Cancer Colorectal
Evaluation of Letters Promoting Colorectal Cancer Testing
In this evaluation, 4 different versions of letters are being sent with mailers promoting colorectal cancer screening with an at-home test.
- Trial name
- NCT04548765
- Testing
- Letter, Loss Frame and Fear Appeals, Transparency
- Where
- United States
- Volunteers
- 14,644 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Colonoscopy
Comparisons of SWI, WWI and CI in Potentially Difficult Colonoscopy.
Colonoscopy insertion is technically challenging, time-consuming, and painful, especially for the sigmoid. It is reported that the difficult colonoscopy score (DCS) >1 can predict the difficulty during colonoscopy.
- Trial name
- NCT03571061
- Testing
- whole colon water immersion and sigmoid water immersion
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Shenzhen People's Hospital
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