Clinical trials: Colonoscopy Procedures
Abdominal Pain
Impact of Carbon Dioxide Insufflation and Water Exchange on Post-Colonoscopy Outcomes
Room air insufflated during colonoscopy cannot be completely suctioned, is not easily absorbed and remains in the bowel for quite some time, resulting in prolonged bowel distension with the discomfort of bloating.
- Trial name
- NCT02409979
- Testing
- Carbon dioxide method, Water Exchange-CO2, Water Exchange-AI
- Where
- 3 sites in United States, Czechia and 1 more
- Volunteers
- 246 people
- Sponsor
- Presidio Ospedaliero Santa Barbara
Cognition, Sedation
Cognitive Function in Geriatric Colonoscopy Patients
Procedures such as colonoscopy cause discomfort and pain and are therefore performed under sedation and analgesia. Although patients aged 65 and older frequently undergo colonoscopy procedures, it is unclear to what extent the…
- Conditions
- Cognition, Sedation, Geriatric Anesthesia, Frailty
- Trial name
- NCT07384169
- Testing
- Propofol Group, Dexmedetomidine group
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people
- Sponsor
- Ankara City Hospital Bilkent
Polyps
Automated Telephone Reminder for Colonoscopy
This is a quality improvement study to determine the impact of an automated telephone reminder on the quality of bowel preparation in patients undergoing outpatient colonoscopy.
- Trial name
- NCT02478918
- Testing
- Phone call
- Where
- Canada
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Queen's University
Acute Kidney Injuries
the Percent of AKI Occurred in Patient With Comorbidities Undergoing Colonoscopy
observation the percent AKI in patient with comorbidities undergoing colonoscopy
- Trial name
- NCT06743815
- Volunteers
- 113 people
- Sponsor
- Assiut University
Colorectal Cancer
PillCam Colon Capsule and CT-colonography in the Evaluation of Patients With Incomplete Conventional Colonoscopy
Colorectal cancer (CRC) is the second most common cause of cancer-related death in the Western world, with 500000 deaths per year worldwide. Colonoscopy is accepted as a primary CRC screening tool in many countries.
- Trial name
- NCT01525940
- Testing
- PillCam Colon Capsule Endoscopy (Given® Diagnostic System)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Colon Disease, Educational Problems
Patient Education and Text Message Reminders in Colonoscopy
This study will be conducted to examine the effects of detailed education and text message reminders given to patients undergoing colonoscopy on bowel cleansing, vital signs and anxiety.
- Trial name
- NCT06073782
- Testing
- Education Group, Text Message Group
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Amasya University
Manual Pressure, Repositioning
Water Exchange and CO2 Insufflation With Abdominal Compression Device to Reduce Manual Assistance
The goal of this trial is to evaluate whether water exchange colonoscopy and CO2-insufflation colonoscopy with an abdominal compression device (Maxbelt me3 type, Nippon Sigmax Co., Tokyo, Japan) can achieve a significantly lower…
- Conditions
- Manual Pressure, Repositioning, Colonoscopy, Colon Polyp
- Trial name
- NCT06496958
- Testing
- CO2 insufflation with an abdominal compression device, Water exchange colonoscopy
- Where
- 2 sites in Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Evergreen General Hospital, Taiwan
Colo-rectal Polyps, Colonoscopy
Comparison of the Diagnostic Accuracy Between Three Dimensional and Standard Colonoscopy of Colorectal Polyps
Colorectal cancer (CRC) is one of the most common cancers worldwide. These malignancies originate in the colon or rectum, and the majority evolve from pre-existing colonic adenomas (a type of colon polyp).
- Trial name
- NCT07619248
- Testing
- 3D MonoStereo
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
Artificial Intelligence, Colonoscopy
AI-assisted Colonoscopy Report System In Improving Reporting Quality
In this study, the investigators proposed a prospective study about the effectiveness of speech and image recognition-based system in improving reporting quality during colonoscopy for colonoscopy report quality in endoscopists.
- Trial name
- NCT05829590
- Testing
- Artificial intelligence assistant system
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Anesthesia
Propofol-fentanyl-ketamine (PFK) Combination Versus General Anesthesia Using Propofol and Fentanyl in Patients Undergoing Endoscopic Procedures.
Conscious sedation provides adequate control of pain and anxiety for the majority of routine endoscopic procedures as well as adequate amnesia.
- Trial name
- NCT04473846
- Testing
- PK general anesthesia, PFK combination
- Where
- Jordan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Adenomatous Polyp, New Imaging Techniques in Colonoscopy
Narrow Band Imaging Colon Polyp Study
In this study the investigators hypothesize that High Definition White Light colonoscopy and narrow band imaging (NBI) will detect a higher number of adenomas compared to standard definition white light colonoscopy.
- Trial name
- NCT00614770
- Testing
- standard of care colonoscopy, colonoscopy
- Where
- 2 sites in United States
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Kansas City Veteran Affairs Medical Center
Pain, Side Effect
Analgosedation for Elective Colonoscopy
Aim: The aim of the study was to to compare the analgesic effects of ketamine over fentanyl combined with propofol in analgesia-based elective colonoscopy with purpose of patient safety and satisfaction.
- Trial name
- NCT05421962
- Testing
- Ketamine
- Where
- Bosnia and Herzegovina
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cantonal Hospital Zenica
Narcotism
Application of Propofol Mixed With Remifentanil in Fiber Colonoscopyand Analgesia in Fiber Colonoscopy
Fiber colonoscopy, as a terminal examination method for lower gastrointestinal diseases, often brings varying degrees of pain, discomfort, tension, and anxiety to patients.
- Trial name
- NCT06175156
- Testing
- Controlled analgesia/sedation, Intravenous combined anesthesia
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Handan First Hospital
Pain
Electrical Stimulation Over Acupuncture Points in Reduction of Rectal Discomfort Distension
Colonoscopy is a stressful and unpleasant procedure especially during the passage of the endoscope through angulations of colon. Electro-acupuncture is one of the alternative to reduce colorectal discomfort.
- Trial name
- NCT01551654
- Testing
- Transcutaneous Electrical Nerve Stimulation (ITO Company )
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Cancer, Colon Cancer
Pilot Study of Colon Cancer Screening Tests
Colon cancer is the second leading cause of cancer death in North America. These deaths are preventable with proper screening. Fecal occult blood testing, virtual colonoscopy, and standard (optical) colonoscopy are all options…
- Conditions
- Colorectal Cancer, Colon Cancer, Adenomatous Polyps
- Trial name
- NCT00865527
- Testing
- Fecal occult blood test, Virtual colonoscopy, Optical colonoscopy
- Where
- Canada
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Colonic Polyp, Colonic Adenoma
Abdominal Compression Administered Early by the Colonoscopist During Water Exchange Colonoscopy
Loop formation is the most frequent cause of cecal intubation failure during colonoscopy. To reduce the loop formation, external abdominal pressure is widely used and proved to be helpful.
- Trial name
- NCT03954561
- Testing
- endoscopist-administered abdominal compression, assistant-administered abdominal compression
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Dalin Tzu Chi General Hospital
Colorectal Cancer
Colonoscopy Followup After Positive Fecal Occult Blood Test- Understanding Barriers to Adherence
Approximately 40% of members with a positive fecal occult blood result do not continue to followup colonoscopy in Meuhedet. The purpose of this study is to identify the structural, process, carer and patient related causes of…
- Trial name
- NCT02534142
- Where
- Israel
- Volunteers
- 774 people, healthy volunteers welcome
- Sponsor
- Meuhedet. Healthcare Organization
Incomplete Colonoscopy, CT Colonography
Patients With Incomplete Colonoscopy a Comparison of Colon Capsule Endoscopy and CT Colonography
A total of 8000 colonoscopies are performed on a yearly basis on the Funen Island. Between 5% and 10% of those are incomplete due to excessive pain, fixed colon loops, and other reasons.
- Conditions
- Incomplete Colonoscopy, CT Colonography, Camera Capsule Endoscopy
- Trial name
- CfC100 (NCT02826993)
- Testing
- CCE in incomplete Colonoscopies
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Colonoscopy
External, Multicentre Validation of a Machine-Learning Model to Predict Colonic Adenoma in Indian Adults
Colorectal adenomas are precursors to colorectal cancer (CRC). Accurate pre-procedure risk stratification could optimize colonoscopy yield and resource allocation in India, where adenoma prevalence varies by age, sex, and…
- Trial name
- NCT07329816
- Testing
- Not Applicable / Observational study
- Volunteers
- 1,000 people
- Sponsor
- Asian Institute of Gastroenterology, India
Bowel Cleansing
A Trial Comparing the PICOPREP Tailored Dosing Schedule to the PICOPREP Day-before Dosing Schedule for Colon Cleansing in Preparation for Colonoscopy
This was a phase 3, randomised, assessor-blinded, multi-centre trial comparing the efficacy, safety and tolerability of a PICOPREP tailored dosing schedule to the PICOPREP day-before dosing schedule for colon cleansing in…
- Trial name
- OPTIMA (NCT02239692)
- Testing
- PICOPREP
- Where
- 3 sites in France, Germany and 1 more
- Volunteers
- 204 people
- Sponsor
- Ferring Pharmaceuticals
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