Clinical trials: Color Blindness
Achromatopsia
Long-Term Follow-Up Gene Therapy Study for Achromatopsia CNGB3 and CNGA3
This is a longer-term follow-up study of patients with achromatopsia associated with defects in CNGA3 who participated in a clinical trial in which they received AAV-CNGA3 retinal gene therapy, or of patients with achromatopsia…
- Trial name
- NCT03278873
- Testing
- Prior exposure to AAV-CNGA3 or AAV-CNGB3
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 34 people
- Sponsor
- MeiraGTx UK II Ltd
Blindness
Do Blue-Blocking Lenses Block Blue Colour From Our Lives?
To measure colour vision in patients with a blue light filtering lens implant in one eye and non-tinted implant in the other eye (and compared this group with a control group with bilateral non-tinted implants) and to determine…
- Trial name
- NCT00403143
- Testing
- cataract surgery
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- London North West Healthcare NHS Trust
Visual Impairment and Blindness (Excl Colour Blindness)
A Trial of Tai Chi Intervention for Youngsters with Visual Impairments
Investigators conducted a single-blind, randomized trial of Taijiquan exercise as compared with a control intervention consisting of wellness education and jogging for youngsters with visual impairments.
- Trial name
- NCT06450340
- Testing
- Moderate-intensity aerobic exercise refers to rhythmic and long-lasting exercise with increased heart rate, slight sweating and slight wheezing.
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Yanyun Zhang
Bipolar Disorder
MAPP: Imagery-focused Therapy for Bipolar Disorder
Bipolar Disorder (BD) (previously known as "manic depression") is a severe mental health illness affecting at least 1% of the population and with annual NHS cost estimated at £342 million.
- Trial name
- MAPP (NCT01981018)
- Testing
- Imagery-focused Cognitive Therapy (ImCT - psychotherapy based on CBT principles)
- Where
- 4 sites in United Kingdom
- Volunteers
- 15 people
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Psychosis
Culturally Adapted Family Intervention For Psychosis
Aim: To assess the feasibility of culturally adapted Family Intervention for Psychosis. Design: Randomized Control Trial Setting: psychiatric department of different hospitals Participants: A total of 36 caregivers of Psychosis…
- Trial name
- NCT02167347
- Testing
- Family intervention
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Pakistan Institute of Living and Learning
Age Related Macular Degeneration, Retinitis Pigmentosa
Visual Activity Evoked by Infrared in Humans After Dark Adaptation
This pilot study will evaluate the visual response to infrared (IR) in humans after dark adaptation. The investigators plan to determine which wavelength and intensity the human eye is most sensitive to in healthy and color-blind…
- Conditions
- Age Related Macular Degeneration, Retinitis Pigmentosa, Congenital Stationary Night Blindness, Colorblindness
- Trial name
- NCT02909985
- Testing
- Tungsten halogen light with narrow bandpass filters
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Smoking Cessation
Cognitive-Behavioral Therapy and Hypnotherapy for Smoking Cessation
Intensive cognitive-behaviour interventions (CBT) combined with pharmacotherapy for smoking cessation are well established and have been proved to be efficacious.
- Trial name
- CBT-HT (NCT01129999)
- Testing
- Cognitive-Behavioral Therapy, Hypnotherapy
- Where
- Germany
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Tinnitus
A CBT-based Internet Intervention for Adults With Tinnitus in the United Kingdom
The purpose of this study is to determine the feasibility and effectiveness of a CBT-based internet intervention for adults with tinnitus in the United Kingdom
- Trial name
- NCT02370810
- Testing
- CBT-based internet-intervention for tinnitus
- Where
- United Kingdom
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Anglia Ruskin University
Chronic Pain
Acceptance and Commitment Therapy and Cognitive Behavioral Therapy for Chronic Pain
Chronic pain is a long-term condition which is related to a number of negative consequences including reduced productivity at work, increased number of sick leave , depression and emotional difficulties among others.
- Trial name
- ALGEA (NCT02778737)
- Testing
- ACT-based intervention, CBT-based intervention
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- University of Cyprus
Psychosis
Culturally Adapted Cognitive Behavior Therapy for Psychosis in Pakistan
Aim: To assess the feasibility of application of culturally-adapted CBT (CaCBTp) for use in Pakistan. Design: Randomized Control Trial Setting: Psychiatry Departments of General Hospitals in Karachi.
- Trial name
- NCT02202694
- Testing
- Culturally Adapted Cognitive behavior therapy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Pakistan Institute of Living and Learning
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
MIRAGE Study: Clinical Outcomes of the Mamba Sirolimus-Eluting PTCA Balloon
This Clinical Evaluation Report (CER) covers the Mamba Sirolimus-Eluting PTCA Balloon catheter intended for the treatment of coronary artery disease in de novo or in-stent restenosis lesions.
- Trial name
- NCT07326735
- Testing
- Mamba Sirolimus-Eluting PTCA Balloon, Percutaneous Coronary Angioplasty with Sirolimus-Coated Balloon
- Where
- 2 sites in Burma, Malaysia
- Volunteers
- 360 people
- Sponsor
- Frisch Medical Device Private Limited
Achromatopsia
Clinical and Genetic Characterization of Individuals With Achromatopsia
The purpose of this study is to identify individuals with achromatopsia caused by mutations in the CNGB3 gene and characterize their clinical condition using several tests of visual function every 6 months for up to 1.5 years.
- Trial name
- NCT01846052
- Where
- 5 sites in United States
- Volunteers
- 56 people
- Sponsor
- Beacon Therapeutics
Achromatopsia
Gene Therapy for Achromatopsia (CNGA3)
A clinical trial of adeno-associated virus vector (AAV) CNGA3 retinal gene therapy for patients with achromatopsia
- Trial name
- CNGA3 (NCT03758404)
- Testing
- adeno-associated virus vector AAV- CNGA3
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 11 people
- Sponsor
- MeiraGTx UK II Ltd
Color Vision Defects
Feasibility of EnChroma Use in the Emergency Department Setting
This study addresses whether the use of EnChroma products are feasible for use in the emergency department by color vision deficient providers.
- Trial name
- NCT04021914
- Testing
- EnChroma glasses
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Emory University
Glaucoma
Incidence of Dyschromatopsia in Glaucoma
Incidence of dyschromatopsia
- Trial name
- NCT02966678
- Testing
- Color Vision Test
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Achromatopsia
Safety and Efficacy of rAAV.hCNGA3 Gene Therapy in Patients With CNGA3-linked Achromatopsia
The purpose of this study is to proof the safety and efficacy of a single bilateral subretinal injection of rAAV.hCNGA3 in adult and minor patients with CNGA3-linked achromatopsia.
- Trial name
- Colourbridge (NCT02610582)
- Testing
- rAAV.hCNGA3
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- STZ eyetrial
Tooth Decay
This Research Study Examines the Effects of Cannabidiol-infused Candy on Reducing the Bacteria Causing Tooth Decay, When Comparing it to a Sugar Free Candy on Adults.
The goal of this clinical trial is to compare the effect of CBD candy versus sugar free candy on reducing the number of bacteria causing tooth decay, in adults The main question is to see whether CBD have any effect on reducing…
- Trial name
- NCT06301113
- Testing
- CBD infused candy, Sugar free Candy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- West Coast University
Suicide Attempt
Treating Suicidality Remotely
Background: Practical and psychological barriers make it difficult for people with Suicidal Thoughts and Behaviors (STBs) to get professional help.
- Trial name
- TREASURE (NCT06370104)
- Testing
- Brief Cognitive Behavioral Therapy for Suicide Prevention, Living under control
- Where
- Netherlands
- Volunteers
- 364 people
- Sponsor
- 113 Suicide Prevention
Color Blindness, Color Vision Defects
Impact of Color Correcting Lenses on Color Vision Deficiency
To demonstrate improved color vision in subjects with color vision deficiencies while wearing color-correcting lenses and after color-correcting lense use.
- Conditions
- Color Blindness, Color Vision Defects, Color Blindness, Green, Color Blindness, Red
- Trial name
- NCT05463016
- Testing
- Experimental Group 1: Color Correcting Lenses, Color Correcting Lenses in Subjects with Normal Color Vision
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of the Incarnate Word
Open Angle Glaucoma
Prevalence of Dyschromatopsia in Glaucoma Patients
Glaucoma is a progressive disease resulting in loss of retinal nerve cells and their axons (retinal nerve fibers). Retinal nerve fibers are ordered in a special manner when they enter the optic nerve.
- Trial name
- NCT01994564
- Where
- United States
- Sponsor
- Massachusetts Eye and Ear Infirmary