Clinical trials: Colorectal Cancer
Colorectal Cancer
The Biomarkers Of RIsk of Colorectal Cancer (BORICC) Follow-Up (BFU) Study
Worldwide, colorectal cancer is the 3rd most common cancer; risk increases with age and is modified by lifestyle factors notably diet, physical activity and obesity.
- Trial name
- BFU (NCT04005742)
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Prevention of Colorectal Cancer
Colon Cancer Prevention Using Selenium
Selenium's ability to prevent colorectal cancer (CRC) has been suspected for nearly 30 years, but has never been directly studied in humans.
- Trial name
- NCT01211561
- Testing
- Selenium, selenomethionine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Colorectal Carcinoma
Dolcanatide in Preventing Colorectal Cancer in Healthy Volunteers
This phase I trial studies how well dolcanatide works in preventing colorectal cancer in healthy participants. Dolcanatide is similar to a natural hormone released into the intestine.
- Trial name
- NCT03300570
- Testing
- Dolcanatide, Laboratory Biomarker Analysis, Questionnaire Administration
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer, Colonoscopy
ColoReg: A Register for Gastrointestinal Endoscopy Reports and Examination Videos
With the participants help, the investigators aim to track treatment methods, treatment outcomes, and adverse events, as well as document the treatment strategies used during endoscopic colorectal cancer prevention and treatment.
- Conditions
- Colorectal Cancer, Colonoscopy, Polypectomy
- Trial name
- NCT06920680
- Where
- 2 sites in Germany
- Volunteers
- 1,834 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Colorectal Cancer
Use and Decision-making About Colorectal Cancer Screening Among Hispanic Men and Women
During this first year, the researchers have worked toward identifying factors influencing initiation of colorectal cancer screening among Hispanic men and women aged 50 and older and developing an intervention plan using…
- Trial name
- NCT00136227
- Testing
- small media intervention using video, flip chart, and pamphlets and a tailored interactive multimedia intervention
- Where
- United States
- Volunteers
- 521 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Colorectal Cancer, Cancer Screening
Small Media Interventions to Increase Colorectal Cancer Screening Among Chinese Americans
There have been few studies of small media interventions to promote colorectal cancer screening among Chinese Americans. Based on the results of strong preliminary studies on the promotion of colorectal cancer screening among…
- Trial name
- SMILES (NCT03174444)
- Testing
- Small Media
- Where
- United States
- Volunteers
- 1,707 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Serrated Polyp, Colorectal Neoplasms
Increasing Serrated Polyp Detection With a Brief Awareness Training
In this non-randomized controlled trial, a semi-random group of Dutch endoscopist receive an oral training about the significance of serrated polyps.
- Trial name
- NCT03902899
- Testing
- Educational intervention (oral presentation)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Colorectal Carcinoma
Addressing Disparities in Colorectal Cancer Screening in Black and Underserved Phoenix Communities
This clinical trial studies disparities involving colorectal cancer prevention and screening in Black and underserved communities in the Phoenix metropolitan area.
- Trial name
- NCT05447923
- Testing
- Educational Intervention, Fecal Immunochemical Test, Patient Navigation
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colorectal Cancer
Comparing the Effectiveness of Written Vs Verbal Advice for First Degree Relatives of Colorectal Cancer Patients
CRC patients were enrolled and asked about their FDR contacts These FDRs were telephoned and enrolled and randomized to receive either written advice and verbal advice about their cancer risk and screening methods.
- Trial name
- NCT06242197
- Testing
- written advice
- Where
- Thailand
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ramathibodi Hospital
Colorectal Cancer (Diagnosis)
The Effectiveness of the mHealth Survivorship Program on Enhancing Health-related Quality of Life Among Colorectal Cancer Survivors
The goal of this clinical trial is to evaluate the effectiveness of the mHealth survivorship program in enhancing health-related quality of life among colorectal cancer survivors.
- Trial name
- NCT07158671
- Testing
- Intervention Group
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- The Nethersole School of Nursing
Cancer
Diagnosis of Cancer Using Breath Samples
The purpose of this study is to collect breath samples from healthy and cancer sick patients. The breath, collected to special bags, will be transferred to laboratories in the Technion and analyzed using an electronic nose system…
- Trial name
- NCT01234987
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Technion, Israel Institute of Technology
Colorectal Surgery, Colorectal Cancer
Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy
The purpose of this study is to evaluate the Colorectal Balloon Tube (hereinafter referred to as COLO-BT™) device, a single use, temporary intraluminal bypass device, intended to reduce contact of fecal content with an…
- Conditions
- Colorectal Surgery, Colorectal Cancer, Rectal/Anal, Ileostomy - Stoma
- Trial name
- COLO-BT (NCT05826743)
- Testing
- COLO BT™, Stoma Creation
- Where
- 3 sites in United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- JSR Medical Co., Ltd.
Colorectal Cancer Screening
Does Numerical And Pictorial Information On Risk And Benefit Affects The Uptake Of Colorectal Cancer Screening?
To establish whether provision of numerical data, framed as event rates and illustrated by pictograms, and including figures for all-cause mortality, affects subjects' attitudes to colorectal cancer (CRC) screening.
- Trial name
- NCT01250015
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- County Durham and Darlington NHS Foundation Trust
Adenomatous Polyps, Colorectal Polyps
Endoscopic Quality Improvement Program
Effective colorectal cancer (CRC) screening relies on early identification and removal of both polypoid and non-polypoid lesions with neoplastic potential.
- Trial name
- EQUIP (NCT01415817)
- Testing
- Training session
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colorectal Cancer, Adenoma
Comparing Detection of Standard Colonoscopy, CAD-EYE and Combined CAD-EYE and G-EYE® Aided Colonoscopy
The purpose of this study is to compare the additional diagnostic yield over Standard Colonoscopy (i.e., the adenoma miss-rate reduction) obtained by performing CADEYE and G-EYE® aided colonoscopy, vs.
- Trial name
- NCT05237310
- Testing
- Standard Colonoscopy, G-EYE Colonoscopy, CAD-EYE
- Where
- Germany
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Colon Cancer
Polyp Detection With the EndoRings™: A Randomized Tandem Colonoscopy Study
To compare the adenoma miss rate with the EndoRings™ vs. the adenoma miss rate with Standard view colonoscopy. To compare the polyp miss rate with the EndoRings™ vs.
- Trial name
- NCT01955122
- Testing
- Tandem Colonoscopy
- Where
- 3 sites in United States, Israel and 1 more
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- EndoAid
Endometrial Cancer, Lynch Syndrome
Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome
Study Goal: This pilot study wants to find out if using a menstrual cup can be a good, non-invasive way to collect samples from the lining of the uterus (called the endometrium) to help screen for endometrial cancer.
- Conditions
- Endometrial Cancer, Lynch Syndrome, Screening, Early Detection of Cancer
- Trial name
- SCREEN-CUP (NCT07220239)
- Testing
- Menstrual cup use
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Jessica D. St. Laurent, MD
Peritoneal Carcinomatosis, Peritoneal Metastases
CAR-T Intraperitoneal Infusions for CEA-Expressing Adenocarcinoma Peritoneal Metastases or Malignant Ascites (IPC)
This is an open-label, dose-escalation, phase I trial of the safety and efficacy of anti-CEA intraperitoneal CAR-T infusions for treatment in patients with CEA-expressing adenocarcinoma peritoneal metastases or malignant ascites.
- Conditions
- Peritoneal Carcinomatosis, Peritoneal Metastases, Colorectal Cancer, Gastric Cancer
- Trial name
- NCT03682744
- Testing
- anti-CEA CAR-T cells
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sorrento Therapeutics, Inc.
Colorectal Neoplasms
Third Eye Retroscope Randomized Clinical Evaluation
The Third Eye® Retroscope® is a device that can be inserted through the instrument channel of a standard colonoscope to provide an additional, retrograde (or backward) view that reveals areas behind folds and flexures in the…
- Trial name
- TERRACE (NCT01044732)
- Testing
- Third Eye Retroscope
- Where
- 9 sites in United States, Belgium and 3 more
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Avantis Medical Systems
Colorectal Cancer Screening
Effectiveness of a Cloud-based Digital Health Navigation Program for Colorectal Cancer Screening
mPATH-CRC (mobile Patient Technology for Health) is an automated direct-to-patient digital health program about colorectal cancer screening.
- Trial name
- NCT06821009
- Testing
- mPATH-CRC, Usual Care (Control)
- Where
- 2 sites in United States
- Volunteers
- 6,500 people, healthy volunteers welcome
- Sponsor
- Digital Health Navigation Solutions, Inc
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