Clinical trials: Colorectal Cancer
Colorectal Cancer
Community Collaboration to Advance Racial/Ethnic Equity in CRC Screening
The goal of this pragmatic randomized clinical trial is to compare two colorectal (CRC) screening outreach approaches (FIT and Cologuard) in community health centers (CHC) in patients overdue for CRC screening.
- Trial name
- CARES (NCT05714644)
- Testing
- FIT kit Screening Test, Cologuard Screening Test
- Where
- 3 sites in United States
- Volunteers
- 5,127 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Screening Colonoscopy for Low Risk Subjects
First in Man Aer-O-Scope
A single center study intended to evaluate the Aer-O-Scope Colonoscope System.
- Trial name
- NCT02102412
- Testing
- screening colonoscopy
- Where
- Croatia
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- GI View Ltd.
Colorectal Cancer
Barriers to Care in Patients With Rectal Bleeding in Nigeria
This study sought to find the health seeking behavior of patients with rectal bleeding as related to their risk to develop colorectal cancer and also assess the general practitioner's perceived barriers to colonoscopy for…
- Trial name
- NCT02855385
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Obafemi Awolowo University Teaching Hospital
Bladder Cancer, Glioma
Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer
The objective of this study is to assess two novel positron emission tomography (PET) radiotracers, [64Cu]CM500 and [68Ga]CM500, for Positron Emission Tomography-Magnetic Resonance Imaging (PET-MR) and Positron Emission…
- Conditions
- Bladder Cancer, Glioma, Glioblastoma (GBM), Breast Cancer
- Trial name
- NCT07781852
- Testing
- [64Cu]CM500, [68Ga]CM500, PET/MR
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lumina Pharmaceuticals Inc
Hereditary Breast and Ovarian Cancer Syndrome, Lynch Syndrome
Pediatric Reporting of Adult-Onset Genomic Results
The Investigators will conduct a longitudinal, mixed-methods cohort study to assess primary and secondary psychosocial outcomes among MyCode adolescent participants and their parents, and health behaviors of children who received…
- Conditions
- Hereditary Breast and Ovarian Cancer Syndrome, Lynch Syndrome, Familial Hypercholesterolemia
- Trial name
- NCT03832985
- Testing
- Child(ren) receive an adult-onset result, Child(ren) received a pediatric-onset result, Control - Negative Result
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Rectal Cancer
A Questionnaire to Assess the Quality of Life of Rectal Cancer Patients With or Without Stoma
The aim of the present prospective study was to evaluate the prediction accuracy of EORTC QLQ-C30/C38 questionnaire in rectal cancer patient(RC).
- Trial name
- NCT01181557
- Where
- Italy
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Colorectal Cancer
The C-SPAN Coalition: Colorectal Cancer Screening and Patient Navigation
Participants will be mailed an invitation to complete CRC screening along with a fecal immunochemical test (FIT) kit, containing a 1-sample "Polymedco Over the Counter (OC) Sensor FIT", simplified English/Spanish instructions on…
- Trial name
- C-SPAN (NCT03181334)
- Testing
- Branch I, Branch II, Branch III
- Where
- 2 sites in United States
- Volunteers
- 7,711 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Caregiver, Malignant Neoplasm
Patient Portal and Navigation Program in Providing Information for Asian American Cancer Patients
This phase I/II trial studies how well patient portal and navigation program work in providing information for Asian American cancer patients.
- Conditions
- Caregiver, Malignant Neoplasm, Physician, Stage I Colorectal Cancer AJCC v8
- Trial name
- NCT03867916
- Testing
- Patient Navigation Program, Quality-of-Life Assessment, Survey Administration
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Colorectal Cancer (CRC) Screening
Evaluation of the Performance of the CleanC System-Israel
The Motus GI Colon Cleansing device is intended to facilitate intra-procedural cleaning of a poorly prepared colon by irrigating the colon and evacuating the irrigation fluid and feces.
- Trial name
- NCT02387268
- Testing
- CleanC system
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Screening Colonoscopy, Surveillance Colonoscopy
A Study to Evaluate the Safety and Efficacy of the Use of ME-APDS During Colonoscopy
ME-APDS is a device (software-based with hardware) developed by Magentiq Eye LTD and intended to support the decision of the endoscopist on polyps which appear in the colonoscopy video during the colonoscopy procedure.
- Trial name
- NCT04640792
- Testing
- Screening or Surveillance Conventionall colonoscopy
- Where
- 11 sites in United States, Germany and 2 more
- Volunteers
- 952 people, healthy volunteers welcome
- Sponsor
- Magentiq Eye LTD
Colorectal Cancer
Improving Colon Cancer Screening for Diverse Populations
This study is a multi-site randomized, controlled trial testing the effect of a combined intervention that includes a colorectal cancer (CRC) screening decision aid plus patient navigation in a diverse, primary care patient…
- Trial name
- NCT02054598
- Testing
- Decision aid and navigation
- Where
- 3 sites in United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
MutYH-associated Polyposis
MUTYH-associated Polyposis
This is single-center, prospective, non-randomized study
- Trial name
- MAP (NCT03847532)
- Testing
- Sanger sequencing method
- Where
- Russia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Colorectal Cancer
The Benefits of Deep Neuromuscular Block and Sugammadex in Laparoscopic Colorectal Surgery
Pneumoperitoneum, the use of carbon dioxide, presents some disadvantages, including a risk of hypercarbia and respiratory acidosis during surgery in the respiratory system, and of an increased mean arterial pressure and systemic…
- Trial name
- NCT02266056
- Testing
- Deep neuromuscular block using rocuronium and reversal with suggamadex, Moderate neuromuscular block using rocuronium and reversal with suggamadex
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Colon Cancer
Colon Cancer Risk-stratification Via Optical Analysis of Rectal Ultrastructure
This is a study whose focus is on understanding the clinical utility of rectal ultrastructure in detecting colonic neoplasm. The method uses Low-coherence Enhanced Backscattering Spectroscopy (LEBS).
- Trial name
- NCT02730702
- Testing
- LEBS - Low coherence enhanced backscattering
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- American BioOptics, LLC
Colorectal Cancer
Colorectal Cancer Detection by Means of Optical Fluoroscopy
The aim of the present prospective study was to investigate the fluorescence emission of human blood plasma of patients with colorectal cancer.
- Trial name
- NCT01286064
- Testing
- Optical Fluoroscopy
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Colorectal Cancer, Colorectal Polyps
Does Inspection During Insertion Improve Adenoma Yields During Colonoscopy?
Colonoscopy is not a perfect test. It misses a substantial number of neoplastic lesions and has some risk of missing cancer. Nearly all work on detection during colonoscopy has focused on the withdrawal phase of the examination.
- Trial name
- NCT01035775
- Testing
- Inspection during insertion, Inspection during withdrawal
- Where
- 2 sites in United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colorectal Carcinoma, Obesity-Related Malignant Neoplasm
A Dietary Intervention (Soy Soft Pretzels) for Reducing Chronic Inflammation in Obese Individuals
This clinical trial compares the effects of soy soft pretzels versus wheat pretzels on inflammatory markers in individuals with obesity.
- Trial name
- NCT07650409
- Testing
- Biospecimen Collection, Dietary Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Rectal Cancer (Stage III)
Diagnostic Accuracy and Prognostic Value of 18F FDG PET-CT in the Follow up of Patients With Colorectal Carcinoma.
The goal of this observational study is to learn about the diagnostic and prognostic value of 18f fdg pet ct in follow up of colorectal cancer patients The main question it aims to answer is: Does pet ct have a role in treatment…
- Trial name
- NCT07536321
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Assiut University
Colorectal Neoplasms
Third Eye Retroscope Randomized Clinical Evaluation
The Third Eye® Retroscope® is a device that can be inserted through the instrument channel of a standard colonoscope to provide an additional, retrograde (or backward) view that reveals areas behind folds and flexures in the…
- Trial name
- TERRACE (NCT01044732)
- Testing
- Third Eye Retroscope
- Where
- 9 sites in United States, Belgium and 3 more
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Avantis Medical Systems
Colon Adenocarcinoma, Colorectal Adenocarcinoma
Family Communications After Genetic Testing
This clinical trial compares patient (proband)-mediated communication to provider-mediated communication for improving genetic testing in first-degree relatives of patients with newly diagnosed colorectal cancer.
- Conditions
- Colon Adenocarcinoma, Colorectal Adenocarcinoma, Rectal Adenocarcinoma, Stage I Colon Cancer AJCC v8
- Trial name
- NCT07143487
- Testing
- Biospecimen Collection, Genetic Testing, Communication Intervention
- Where
- 365 sites in United States, Puerto Rico
- Volunteers
- 4,186 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
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