Clinical trials: Colorectal Cancer Screening
Colorectal Carcinoma
Blood Test (Guardant Shield™) for Screening of Colorectal Cancer in Underserved Patients
This clinical trial evaluates the use of a blood test (Guardant Shield™) for colorectal cancer screening. Colorectal cancer is the third leading cancer and cause of death in the United States.
- Trial name
- NCT05716477
- Testing
- Biospecimen Collection, Survey Administration
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Colorectal Carcinoma
Educational Intervention - Improving Knowledge and Screening Rates for Colorectal Cancer
This clinical trial studies how well educational intervention works in improving knowledge and screening rates of colorectal cancer.
- Trial name
- NCT03287453
- Testing
- Educational Intervention, Survey Administration
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Colorectal Cancer
Efficacy of a Mobile Clinical Decision Support System (CaPtyVa CCR App) to Improve Performance of Gastroenterology and Coloproctology Specialists in Colorectal Cancer Screening and Surveillance According to Guideline Recommendations: A Randomized Clinical Trial.
This prospective study evaluates the use of a (Mobile Decision Support Systems), MDSS (CaPtyVa CCR app) in order to improves gastroenterology and coloproctology specialist's performance in CRC screening and surveillance according…
- Trial name
- NCT04389502
- Testing
- CaPtyVa app, Control group
- Where
- Argentina
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital Aleman
Colorectal Cancer Screening
Validation of Advanced Colorectal Neoplasm Risk Categories in a Prospective Cohort in Mexico
Worldwide, there are 1,361,000 new cases of colorectal cancers (CRC) annually, with 694,000 deaths. However, the incidence varies by up to a factor of 10x between high and low incidence countries (eg.
- Trial name
- COLOFIT (NCT05661292)
- Testing
- Fecal inmunochemical test, Colonoscopy, Optional collection of tissue, blood and urine for future biomedical research
- Where
- Mexico
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Colorectal Cancer, Colorectal Adenomas
Water Exchange Versus Carbon Dioxide for Colonoscopy
Colonoscopy is commonly used in screening for colorectal cancer. A refined technique of colonoscopy involving the use of water as the sole modality to aid colonoscope insertion, water exchange, has been described in recent…
- Conditions
- Colorectal Cancer, Colorectal Adenomas, Colorectal Polyps, Pain
- Trial name
- NCT01633333
- Testing
- Water exchange colonoscopy, Carbon dioxide insufflation
- Where
- 3 sites in Norway, Poland
- Volunteers
- 473 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Cancer Colon
Blood-Based Colorectal Cancer (CRC) Screening Implementation Into Clinical Practice Highlands
This is a prospective implementation study that will include patients that are identified as being average risk for colorectal cancer (CRC) according to USPSTF guidelines and who have opted to be screened for CRC.
- Trial name
- NCT06119425
- Testing
- blood-based CRC screening
- Where
- United States
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Ballad Health
Colon Cancer
Novel Biophotonics Methodology for Colon Cancer Screening
The study is testing a new, safe and effective way for the early detection of colon cancer. The method uses Low-coherence Enhanced Backscattering Spectroscopy (LEBS).
- Trial name
- BRP (NCT01999478)
- Where
- 5 sites in United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Colorectal Neoplasms, Colonic Polyps
Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities
The purpose of this study is to determine if a new device, called the Endocuff Vision (a small plastic device attached to the end of the colonoscope which helps by holding the folds of the bowel back to give a clear view of the…
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Adenoma
- Trial name
- ADENOMA (NCT02552017)
- Testing
- Endocuff Vision
- Where
- 7 sites in United Kingdom
- Volunteers
- 1,772 people, healthy volunteers welcome
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Colorectal Neoplasms
Randomized Controlled Trial of Tailored Interactive Multimedia to Reduce Colorectal Cancer Screening Disparities
The study investigators have developed an interactive multimedia computer program that provides personally tailored education about colorectal cancer screening in the user's preferred language (English or Spanish).
- Trial name
- NCT00786747
- Testing
- Personally tailored computer program, Non-tailored control computer program
- Where
- 5 sites in United States
- Volunteers
- 1,164 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Colorectal Cancer
A Community Population Screening Cohort Study Based on Polygene Methylation Detection for Colorectal Cancer in Yangzhou
This is a cross-sectional cohort study based on community population jointly developed by Northern Jiangsu People's Hospital and Shanghai Kunyuan Biological Technology Co., LTD.
- Trial name
- NCT05336539
- Where
- 2 sites in China
- Volunteers
- 80,000 people, healthy volunteers welcome
- Sponsor
- Singlera Genomics Inc.
Colorectal Cancer
Young-onset Colorectal Cancer Screening Based on Artificial Intelligence
In this study, we aimed to develop, internally and temporally validate the machine learning models to help screen YOCRC bansed on the retrospective extracted Electronic Medical Records (EMR) data.
- Trial name
- NCT06342622
- Testing
- Using routine clinical data and machine learning models.
- Where
- China
- Volunteers
- 11,000 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Colorectal Cancer Control and Prevention
Life Expectancy-informed Colorectal Cancer Screening
The purpose of this study is to improve life-expectancy concordant colorectal cancer screening for adults over 75 years through design and testing of a life expectancy notification to clinicians delivered via the electronic…
- Trial name
- CRC (NCT07141901)
- Testing
- Decision Tool
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Kathryn Martinez
Thoracic Cancer, Ovarian Cancer
Project CADENCE (CAncer Detected Early caN be CurEd)
With existing evidence showing the difference in miRNA expression levels between non-cancer and cancer groups, the investigators assume that levels of DNA methylation, RNA expression as well as protein concentration will also be…
- Conditions
- Thoracic Cancer, Ovarian Cancer, Liver Cancer, Prostate Cancer
- Trial name
- CADENCE (NCT05633342)
- Where
- Singapore
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- MiRXES Pte Ltd
Colorectal Carcinoma
Online Mindfulness-Based Intervention to Decrease Pre-Procedural Anxiety Before a First-Time Screening Colonoscopy
This clinical trial tests how well an online mindfulness-based intervention (MBI) works to decrease anxiety in patients before a first-time screening colonoscopy.
- Trial name
- NCT06233253
- Testing
- Best Practice, Medical Chart Review, Online Mindfulness Meditation
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Colorectal Cancer, Advanced Adenocarcinoma
Colorectal Cancer and Pre-Cancerous Adenoma Non-Invasive Detection Test Study
This study was a prospective analysis conducted by Geneoscopy Inc. to evaluate the ColoSense test, which is a multi-target stool RNA test for colorectal cancer screening.
- Conditions
- Colorectal Cancer, Advanced Adenocarcinoma, Serrated Polyp
- Trial name
- CRC-PREVENT (NCT04739722)
- Testing
- ColoSense
- Where
- 2 sites in United States
- Volunteers
- 14,263 people, healthy volunteers welcome
- Sponsor
- Geneoscopy, Inc.
Colorectal Cancer, Adenoma Colon
Characterization of Brazilian Colorectal Cancer Screening Population
Colorectal cancer (CRC) is the third most common type of cancer among men and the second among women in Brazil. Despite the high incidence and significance of CRC in Brazil, very little is known about its prevalence among the…
- Trial name
- NCT03355391
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Barretos Cancer Hospital
Colorectal Cancer
Colorectal Cancer Awareness, Research and Education and Screening - Rural Expansion, Access and Capacity for Health
This study is to assess the impact of the CARES-REACH intervention on colorectal cancer screening rates.
- Trial name
- CARES-REACH (NCT04464668)
- Testing
- Provider Tools, Provider surveys
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Colorectal Cancer Screening, Colonic Polyps/Colonoscopy/Colorectal Neoplasms
The Impact of Image-Assisted Colonoscope on Patient Experience, Physician Workload, and Examination Quality
Colonoscopy is the cornerstone for colorectal cancer screening, diagnosis, and post-treatment surveillance. Procedural quality is influenced by patient anatomy, particularly variations in colonic configuration such as sigmoid…
- Conditions
- Colorectal Cancer Screening, Colonic Polyps/Colonoscopy/Colorectal Neoplasms, Difficult Colonoscopy, Colonoscopy-Related Discomfort
- Trial name
- LOOP-p1 (NCT07541924)
- Testing
- CT-Based Image-Assisted Colonoscope Insertion
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- DONG WU
Colo-rectal Cancer
Assessing Repeat Fit Testing for CRC
This study will randomly assign 220 men and women to either a social media intervention or a standard reminder system to have a repeat screening test for colo-rectal cancer.
- Trial name
- ARFT (NCT03248661)
- Testing
- Now I'm Telling You
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Richard Crosby
Colorectal Cancer
A Smartphone-Based Intervention to Improve Colorectal Cancer Screening in African American Men
The goal of this clinical trial is to test a new smartphone-based program designed to help African American men get screened for colorectal cancer (CRC).
- Trial name
- NCT06052202
- Testing
- CRC mHealth, Control
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- ISA Associates, Inc.