Clinical trials: Colorectal Disorders
Obesity, Colorectal Cancer
Prevention of Obesity-related Cancers: Setting up of a Multi-Cancer Education and Prevention Program in Hong Kong
Obesity could increase the risk of many chronic diseases, including hypertension, cardiovascular diseases, high lipid level, diabetes, stroke, endometrial cancer and certain types of cancer which could benefit by secondary…
- Conditions
- Obesity, Colorectal Cancer, Prostate Cancer, Breast Cancer
- Trial name
- NCT04034953
- Testing
- Faecal Immunochemical Test, Prostate-Specific Antigen Test, Mammogram
- Where
- Hong Kong
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colo-rectal Cancer
Eliminating Barriers to Colorectal Cancer Screening Using Rapid Cycle Testing: A Pilot Study
The investigators will use a mixed methods study i.e. focus groups involving CHC staff as well as quantitative study which involves analyzing data that is available from the EHR and DRVS population management platform.
- Trial name
- NCT05524428
- Testing
- Implementation Science Strategy
- Where
- 4 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Colon Adenocarcinoma, Colorectal Carcinoma
Young-Onset Colorectal Cancer
This study investigates the genetic factors that may influence the risk of developing colorectal cancer at a young age. Finding genetic markers for colorectal may help identify patients who are at risk of colorectal cancer.
- Conditions
- Colon Adenocarcinoma, Colorectal Carcinoma, Rectal Adenocarcinoma
- Trial name
- NCT02863107
- Testing
- Biospecimen Collection, Medical Chart Review, Quality-of-Life Assessment
- Where
- 5 sites in United States
- Volunteers
- 818 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Cancer (CRC)
Raising Awareness of Colorectal Screening in American Indian Communities
This study focuses exclusively on American Indian individuals within their communities to enhance health equity and address a critical tribal health priority.
- Trial name
- AIC-DC (NCT07515729)
- Testing
- Navigator-led intervention
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Colon Cancer
Study of Colorectal Cancer Screening Options
The investigators propose to evaluate Guardant Health's commercially available colorectal cancer screening assay(Guardant SHIELD) in individuals who are not up to date with CRC screening.
- Trial name
- NCT05987709
- Testing
- GuardantSHIELD Blood Test
- Where
- United States
- Volunteers
- 2,004 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obesity, Colorectal Cancer
Time-Restricted Eating and Mindfulness-Based Stress Reduction to Reduce the Risk of Early-Onset Colorectal Cancer
The goal of this clinical trial is to evaluate the feasibility of remote time-restricted eating (TRE) and mindfulness-based stress reduction (MBSR) interventions and the preliminary effect on EOCRC-related markers.
- Conditions
- Obesity, Colorectal Cancer, Microbial Colonization, Time Restricted Feeding
- Trial name
- MBSR&TRE (NCT06022887)
- Testing
- TRE, MBSR
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Lisa Tussing-Humphreys
Colorectal Cancer, Surgical Procedure, Unspecified
Perioperative Management of Colorectal Cancer Patients Infected With COVID-19: a Multicenter Prospective Cohort Study.
This trial is a multicenter prospective cohort study to explore timing of colorectal cancer surgery after COVID-19 infection so that can assist clinicians and patients.
- Trial name
- NCT05682898
- Testing
- Timing of colorectal cancer surgery
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Cancer
Virtual Human Delivered Nutrition Module for Colorectal Cancer Prevention
This study uses the opinions of adults between the ages of 45 and 73 years old to develop and test an interactive nutrition module for use in an existing colorectal cancer screening intervention using virtual human technology.
- Trial name
- NCT04192071
- Testing
- virtual technology - high interactive, virtual technology - low interactive, non-colorectal cancer related module
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University of Florida
Colorectal Cancer Screening, Hepatitis C Virus
Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening
This innovative Multilevel Action Toward Colorectal Cancer (CRC) and Hepatitis C Virus (HCV) Education and Screening (MATCHES) intervention aims to promote concurrent HCV and CRC screening among FQHC patients ages 45-75.
- Trial name
- MATCHES (NCT06745895)
- Testing
- MATCHES
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Colorectal Cancer
Colorectal Cancer Screening in Alaska Native Men
Alaska Native men have the highest rates of colorectal cancer incidence and mortality in the US. Screening can prevent disease and improve survival.
- Trial name
- NCT06436300
- Testing
- Motivational text messaging
- Where
- United States
- Volunteers
- 998 people, healthy volunteers welcome
- Sponsor
- Washington State University
Ovarian Cancer, Fallopian Tube Cancer
Choices About Genetic Testing And Learning Your Risk With Smart Technology
This study seeks to enhance genetic education and increase the uptake of genetic testing for hereditary cancer risk among cancer survivors.
- Conditions
- Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer, Breast Cancer
- Trial name
- CATALYST (NCT06184867)
- Testing
- Relational Agent (RA), Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Colorectal Cancer
Colorectal Cancer Screening Assessment Study
This study, led by the American Samoa Community Cancer Coalition's INdigenous Samoan Partnership to Initiate Research Excellence (INSPIRE) and the UH Cancer Center's project team including Dr.
- Trial name
- NCT04500171
- Testing
- Colocare Instruction Sheet: SAM + CAM SMOG, CDC Colorectal cancer screening for life brochure: SAM + CAM SMOG, Colocare Instruction Sheet: SAM + CAM - Superior rating SMOG - 5th Grade Level
- Where
- 2 sites in American Samoa
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Colon Cancer
Voyage: Real-World Impact of the Multi-target Stool DNA Test on CRC Screening and Mortality
The purpose of this study is to gather information about the long term health of people who have been prescribed the Cologuard test, which is used for colorectal cancer (CRC) screening.
- Trial name
- NCT04124406
- Testing
- Cologuard
- Where
- United States
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Human Papillomavirus Infection
A Phase I Trial Evaluate the Safety and Tolerability Profile of HPV Vaccine
This study is to evaluate the safety and tolerability profile of Recombinant Nonavalent (Types 6/11/16/18/31/33/45/52/58) Human Papillomavirus (HPV) Vaccine (Escherichia Coli) in healthy women ages 18-45
- Trial name
- NCT05680454
- Testing
- Recombinant Nonavalent (Types 6/11/16/18/31/33/45/52/58) Human Papillomavirus (HPV) Vaccine (Escherichia Coli), Recombinant nonavalent Human Papillomavirus (Types 6,11,16,18,31,33,45,52,58) Vaccine
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Beijing Health Guard Biotechnology, Inc
Colorectal Cancer (Diagnosis)
ColoSense Post-Approval Study
The post-approval study (PAS) described here will supplement existing data generated in the CRC-PREVENT clinical trial. The primary outcomes of this supplemental study will include: clinical sensitivity, clinical specificity…
- Trial name
- NCT07069556
- Testing
- ColoSense
- Where
- United States
- Volunteers
- 12,500 people, healthy volunteers welcome
- Sponsor
- Geneoscopy, Inc.
Colonic Neoplasms
Case Series With Saneso 3600 Colonoscope
Saneso colonoscope is a novel FDA cleared colonoscope that provides a 360 degree integrated view of the colon. Saneso colonoscope has five cameras and multiple LED lights at the distal head.
- Trial name
- NCT05505370
- Testing
- Colonoscopy
- Where
- 5 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Saneso Inc.
Colorectal Cancer, Inflammatory Bowel Disease
Changes of Muramyl Dipeptide in Intestinal and Extra-intestinal Diseases
Nucleotide-binding oligomerization domain 2 (Nod2) signaling is critical for human health.To figure out the clinical relevance of NOD2 ligands, the investigators plan to evaluate the change of NOD2 ligands in inflammatory bowel…
- Conditions
- Colorectal Cancer, Inflammatory Bowel Disease, Atherosclerotic Cardiovascular Disease, Type2 Diabetes Mellitus
- Trial name
- NCT04924686
- Testing
- Observational studies, no intervention
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Colorectal Neoplasm
Enhancing Prevention Pathways Toward Tribal Colorectal Health
Recent improvements in colorectal cancer (CRC) incidence, mortality, stage at diagnosis, and survival in the general U.S. population have been attributed to routine screening with prompt removal of polyps, early detection, and…
- Trial name
- NCT02882620
- Testing
- High Intensity (Group 1), Medium Intensity (Group 2), Reference Group (Group 3)
- Where
- United States
- Volunteers
- 1,788 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Colorectal Cancer
e-Motivación: Developing and Pilot Testing an App to Improve Latinos' Screening Colonoscopy Rates
Among Latinos, a fast growing and underserved population, Colorectal Cancer (CRC) is the third leading cause of cancer death in men and in women.
- Trial name
- NCT04987788
- Testing
- Motívate, Video link
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Colorectal Cancer
¡Salud! Por la Vida (SPLV) A Colorectal Screening Promotion Program
The overall goal of this educational program was to increase colorectal cancer screening (CRCS) in men and women who attend Federally Qualified Health Centers (FQHC) in Puerto Rico.
- Trial name
- SPLV (NCT05502666)
- Testing
- ¡Salud! Por la Vida
- Where
- Puerto Rico
- Volunteers
- 445 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
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