Clinical trials: Combat
Stress Disorder, Post-Traumatic
Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance
The purpose of this study is to determine whether prazosin will reduce the incidence of nightmares, sleep disturbance, and overall symptoms in combat trauma-exposed individuals with PTSD.
- Trial name
- NCT00108420
- Testing
- Prazosin
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
HIV, Arterial Stiffness
High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV
This is a single site, randomized exercise trial with individuals at least 50 years of age living with HIV who experience suboptimal cognition.
- Conditions
- HIV, Arterial Stiffness, Cognitive Dysfunction
- Trial name
- NCT05965518
- Testing
- High-Intensity Interval Training, Continuous Moderate Exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Post-Traumatic Stress Disorder, Combat Disorders
Trauma Management Therapy for OEF and OIF Combat Veterans
This trial will evaluate the efficacy and efficiency of Trauma Management Therapy (TMT; Frueh, Turner, Beidel, 1996; Beidel, Frueh, Uhde, under preparation), which combines individual virtual reality (VR) assisted exposure…
- Trial name
- TMT (NCT02809326)
- Testing
- 17 week Exposure Therapy Control Arm, Trauma Management Therapy, Intensive 3-Week Trauma Management Therapy
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Nerve Block, Nerve Blocks
Blast-related Regional Anaesthesia and Peripheral nerVe Injury Evaluation
This randomized study will examine whether ultrasound-guided regional anaesthesia (a nerve block) contributes to new or worsening peripheral nerve problems after blast-related limb trauma.
- Conditions
- Nerve Block, Nerve Blocks, Nerve Injury, Blast Injury
- Trial name
- BRAVE (NCT07879508)
- Testing
- Standardized Multimodal Analgesia, Ultrasound-Guided Regional Anaesthesia
- Volunteers
- 150 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Shift-Work Related Sleep Disturbance
Shift Work Intervention Strategies for Night Shift Workers
The goal of this intervention study is to test behavioral interventions in night shift workers. The main question it aims to answer is: Can personalized sleep or nutrition intervention strategies help against the negative health…
- Trial name
- GRIP (NCT06147089)
- Testing
- Sleep Intervention, Nutritional intervention
- Where
- Netherlands
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Post Traumatic Stress Disorder PTSD, Hazardous Alcohol Use
Multimodal Intervention for Individuals With Posttraumatic Stress Disorder (PTSD) and Hazardous Alcohol Use
This project will test the effectiveness of a stepped-care talk therapy model for patients with PTSD and Hazardous Alcohol use (HAU).
- Trial name
- NCT07903974
- Testing
- Written Exposure Therapy (WET), Clinician Supported PTSD Coach App (CS-PTSD), Phone follow up
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Post Traumatic Stress Disorder PTSD
Shared Decision Making in PTSD Treatment
The purpose of this research study is to learn about how Shared Decision Making, when used to decide treatment, impacts treatment engagement, retention, and outcomes for active duty military personnel seeking treatment for…
- Trial name
- NCT06953687
- Testing
- Prolonged Exposure Therapy, Cognitive Processing Therapy, Written Exposure Therapy
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Sarcopenia in Elderly
RANKL Inhibition to Combat Sarcopenia in Hip Fracture Patients
The objective of this study is to conduct a pragmatic, randomized, double-blind, active-controlled trial to assess the efficacy of receptor activator of nuclear factor-kB ligand (RANKL) inhibition in the treatment of sarcopenia…
- Trial name
- NCT07056478
- Testing
- Denosumab (Prolia), Zoledronic acide (Aclasta)
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
Posttraumatic Stress Disorders, Combat Disorders
Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders
In comparison to the general population, U.S. military and Veterans are at an increased risk for developing both substance use disorders (SUD) and Post Traumatic Stress Disorder (PTSD).
- Conditions
- Posttraumatic Stress Disorders, Combat Disorders, Alcohol Dependence, Drug Dependence
- Trial name
- COPE (NCT01338506)
- Testing
- Concurrent Treatment with Prolonged Exposure (COPE)
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Medical University of South Carolina
Stress Disorders, Post-Traumatic, PTSD
Service Dogs and Prolonged Exposure Therapy for Military-Connected PTSD
This study investigates the impact of Service Dog partnership on the effectiveness of Prolonged Exposure Therapy. We will learn whether Service Dog partnership in combination with Prolonged Exposure Therapy treatment can help…
- Conditions
- Stress Disorders, Post-Traumatic, PTSD, Animal-Human Bonding, Combat Stress Disorders
- Trial name
- SERVES+ (NCT06723834)
- Testing
- Psychiatric Service Dog, Prolonged Exposure Therapy
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- University of Arizona
Stress Disorders, Post-Traumatic
Accelerated Image-Guided Robotically Delivered Transcranial Magnetic Stimulation for Combat PTSD
Posttraumatic stress disorder (PTSD) among military service members and veterans is as high as 32% and is the third most service-connected disability, resulting in over $1.5 billion in direct costs over a five-year period.
- Trial name
- NCT06587659
- Testing
- Transcranial Magnetic Stimulation, Robotic Arm
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Traumatic Brain Injury, Veterans
Awareness of Deficit After Combat-related Brain Injury
This study will use MRI imaging, cognitive testing and outcome questionnaires to determine how the brain recovers and reorganizes after an injury.
- Trial name
- NCT00478400
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury, Hypopituitarism
Hormone Deficiency After Brain Injury During Combat
We would like to ascertain the prevalence of hypopituitarism after combat-related TBI. This will lead to enhanced awareness, recognition, and treatment of hypopituitarism, which can have life-saving ramifications and enhance…
- Trial name
- NCT01666964
- Testing
- Blast Traumatic Brain Injury
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Walter Reed National Military Medical Center
Neuropathic Pain
The Effect of Neuropathic Pain in Patients With Combat-related Extremity Injury
It has been suggested that veterans with chronic pain might be at increased risk for the development of depression, anxiety and post-traumatic stress disorder.
- Trial name
- NCT04674631
- Testing
- The effect of neuropathic pain on quality of life, depression and sleep quality
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Posttraumatic Stress Disorder
Hypnotherapeutic Olfactory Conditioning for Posttraumatic Stress Disorder (PTSD)
Chronic combat-related posttraumatic stress disorder can be difficult to treat. The investigators believe that hypnosis, with a stress on the sensation of scent which often plays a role in the traumatic memories, can offer help…
- Trial name
- NCT00784771
- Testing
- Hypnotherapeutic Olfactory Conditioning (HOC)
- Where
- Israel
- Volunteers
- 36 people
- Sponsor
- Herzog Hospital
Respiratory Muscle Function, Athletic Performance
Effects of Diaphragmatic Breathing Retraining in Combat Sport Athletes With Dysfunctional Breathing Patterns
Combat sport athletes often need to maintain a guarded posture, stabilize the trunk, react quickly, and control balance during contact or unexpected movement.
- Conditions
- Respiratory Muscle Function, Athletic Performance, Postural Balance
- Trial name
- NCT07717801
- Testing
- Diaphragmatic breathing training exercise, Usual training
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng Kung University
Military Operational Stress Reaction, Malnutrition (Calorie)
Physiological Response to Protein and Energy-enhanced Food Products During Winter Military Training
Soldiers commonly lose muscle mass during training and combat operations that produce large energy deficits (i.e., calories burned > calories consumed).
- Conditions
- Military Operational Stress Reaction, Malnutrition (Calorie), Weight Loss, Muscle Wasting
- Trial name
- NCT05210205
- Testing
- EAA, Energy Dense, Control
- Where
- Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
PTSD, PTSD - Post Traumatic Stress Disorder
Efficacy of Eye Movement Desensitization and Reprocessing (EMDR) Therapy Versus Selective Serotonin Reuptake Inhibitors (SSRIs) in the Treatment of Post-Traumatic Stress Disorder
This randomized controlled trial aims to compare the efficacy of Eye Movement Desensitization and Reprocessing (EMDR) therapy versus Selective Serotonin Reuptake Inhibitors (SSRIs) in the treatment of Post-Traumatic Stress…
- Trial name
- NCT06955845
- Testing
- Eye Movement Desensitization and Reprocessing Therapy, Selective serotonin reuptake inhibitors
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Asad Ullah Jan
Posttraumatic Stress Disorder, Combat-related
Predictors of Treatment Response to Fluoxetine in PTSD Following a Recent History of War Zone Stress Exposure
Three hundred (300) male or female outpatients, over 18 years of age, will be enrolled in this study to determine whether fluoxetine can be used as a treatment for Posttraumatic Stress Disorder in soldiers recently returning from…
- Trial name
- NCT00633685
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- TEMPVA Research Group, Inc.
Smoking, Smoking Cessation
Project COMBAT: Combating Tobacco Use in the United States Army
The goal of this behavioral research study is to test a new multimedia anti-tobacco video game tailored to the U.S. Army. Researchers want to study how using the program affects tobacco use in soldiers, as compared to standard…
- Trial name
- NCT00948233
- Testing
- Video Game, Pamphlet, Surveys
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center