Clinical trials: Combat
PTSD - Post Traumatic Stress Disorder
A Frequency-Modulated Music Intervention to Enhance Cognitive Processing Therapy (CPT) for PTSD
The goal of this clinical trial is to learn if the addition of frequency filtered music (Safe and Sound Protocol) to daily cognitive processing therapy improves effectiveness for reducing PTSD symptoms.
- Trial name
- NCT06925867
- Testing
- Frequency Filtered Music, Unfiltered Music, Cognitive Processing Therapy for PTSD
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
PTSD, Stress Disorders, Post - Traumatic
Innovative Delivery of Evidence Based Psychotherapy to Women With Military Sexual Trauma
The purpose of this study is to determine whether a scientifically validated treatment for Posttraumatic Stress Disorder (PTSD) called Prolonged Exposure (PE) can be delivered effectively to Veterans with Military Sexual Trauma…
- Conditions
- PTSD, Stress Disorders, Post - Traumatic, Anxiety Disorders, Mental Disorders
- Trial name
- NCT02417025
- Testing
- PE
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Medical University of South Carolina
Traumatic Brain Injuries, TBI (Traumatic Brain Injury)
Rehabilitation Through Virtual Immersion & Integrated Exposure for Mild Traumatic Brain Injury (ReVIVE for mTBI)
The primary goal of this study is to evaluate the effectiveness of an integrated therapeutic model - combining VR and standard psychotherapy in improving executive function and hyperarousal adults impacted with mTBI.
- Conditions
- Traumatic Brain Injuries, TBI (Traumatic Brain Injury), MTBI - Mild Traumatic Brain Injury, mTBI
- Trial name
- ReVIVE (NCT07890337)
- Testing
- Virtual Reality, Standard Psychotherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Johns Hopkins University
Trauma, Wounds and Injuries
Registry of Emergency Airways Arriving at Combat Hospitals
This represents the first prospective examination of advanced airway management under combat conditions. The findings will have a tremendous impact on both modern prehospital medical practice and on the treatment of our wounded…
- Conditions
- Trauma, Wounds and Injuries, Emergencies
- Trial name
- REACH (NCT01405001)
- Volunteers
- 292 people
- Sponsor
- William Beaumont Army Medical Center
Substance Use Disorder, Post-traumatic Stress Disorder
Mindful Self Compassion for Combat Deployed Veterans With Moral Injury and Co-occurring PTSD-SUD
Veterans with co-occurring Posttraumatic Stress Disorder and Substance Use Disorder (PTSD-SUD) experience more severe symptomatology and poorer response to existing treatments than Veterans with either disorder alone.
- Conditions
- Substance Use Disorder, Post-traumatic Stress Disorder, Moral Injury
- Trial name
- NCT03681288
- Testing
- Mindful Self-Compassion
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- VA Office of Research and Development
Combat Posttraumatic Stess Disorder, Mild Traumatic Brain Injury
Lithium Augmentation for Hyperarousal Symptoms of Post Traumatic Stress Disorder: Pilot Study
The purpose of this study is to explore the effectiveness of adding lithium carbonate (lithium) to treatment for combat-related post traumatic stress disorder in combat veterans.
- Trial name
- NCT01754883
- Testing
- Lithium Carbonate
- Where
- United States
- Sponsor
- VA Eastern Colorado Health Care System
Covid19
The Burden of COVID-19 Survivorship
This research study is being done to find out what the longer-term physiological consequences of COVID-19 are, and to determine if exercise therapy can help improve lung function, heart function and overall fitness, and reduce…
- Trial name
- NCT04913129
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic
Performance Enhancement, Supportive Care
Effects of Wrestling Training on Psychological Well-Being, Anxiety, and Resilience in Adolescent Sedanter Boys
This randomized controlled study investigated the psychological effects of a six-week, non-competitive wrestling training program in sedentary adolescent boys.
- Trial name
- NCT07193121
- Testing
- Wrestling Group, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Posttraumatic Stress Disorder (PTSD)
Project Remission: Maximizing Outcomes With Intensive Treatments for Combat-Related PTSD
The study compares two intensive outpatient behavioral programs (Massed Prolonged Exposure versus Intensive Outpatient Prolonged Exposure) for the treatment of posttraumatic stress disorder (PTSD) in post-9/11 active duty service…
- Trial name
- NCT03529435
- Testing
- Massed Prolonged Exposure, Intensive Outpatient Prolonged Exposure
- Where
- 4 sites in United States
- Volunteers
- 234 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Combat and Operational Stress Reaction
Role of Stress Reduction Protocol on Outcome of Periodontal Therapy
Psychological conditions, particularly psychosocial stress, have been implicated as risk indicators for periodontal disease. Minimal evidence in literature exists to assess the effect of stress reduction therapy (SRT) in the…
- Trial name
- NCT02487862
- Testing
- Stress Reduction Protocol
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
PTSD - Post Traumatic Stress Disorder, Intrusive Memories of Traumatic Event(s)
Neuromodulation of the Hippocampus to Reduce Intrusive Re-Experiencing in PTSD: A Randomized Controlled Trial
The goal of this clinical trial is to learn if non-invasive neurostimulation of memory-related brain areas works to treat intrusive memory symptoms in adults patients with posttraumatic stress disorder (PTSD).
- Trial name
- NCT06639061
- Testing
- Hippocampal stimulation using repetitive transcranial magnetic stimulation (rTMS)
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel Aviv University
Traumatic Brain Injury
CONcussion Treatment After Combat Trauma (CONTACT)
This study compares the effects of Individualized Scheduled Telephone Support (ISTS) and Usual Care (UC) for service members with Mild Traumatic Brain Injury (mTBI). A total of 400 service members will participate in this study.
- Trial name
- CONTACT (NCT01387490)
- Testing
- Individualized Scheduled Telephone Support (ISTS), Usual Care (UC)
- Where
- 4 sites in United States
- Volunteers
- 366 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Stress Disorders, Post-Traumatic, Combat Stress Disorders
Multi-site, Longitudinal Trial Evaluating the Efficacy, Mechanisms, and Moderators of Service Dogs for Military Veterans With PTSD
Posttraumatic stress disorder (PTSD) among military Veterans is a critical public health concern. Veteran suicide rates exceed those of the general population, with the disorder creating a mental health challenge that is costly…
- Conditions
- Stress Disorders, Post-Traumatic, Combat Stress Disorders, Animal-Human Bonding
- Trial name
- NCT05900479
- Testing
- PTSD Service Dog
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of Arizona
Hepatitis B, Vertical Transmission of Infectious Disease
The COMBAT HBV Feasibility Trial
This is a double-blind, randomized placebo-controlled trial (RCT) of a prophylaxis-for-all approach to prevention of mother-to-child transmission (PMTCT) of hepatitis B virus (HBV) in the Democratic Republic of Congo (DRC).
- Trial name
- COMBAT-HBV (NCT05705427)
- Testing
- Tenofovir Disoproxil Fumarate 300 MG, Hepatitis B monovalent vaccine
- Where
- Democratic Republic of the Congo
- Volunteers
- 317 people
- Sponsor
- University of North Carolina, Chapel Hill
Artificial Intelligence
Conversational AI in Tactical Casualty Care: Baseline GPT-4o Improves Combat Medic Decision-Making
The aim of the project is to investigate whether the integration of artificial intelligence (AI) support, specifically through the GPT-4 model, enhances the decision-making processes of military medical first responders within…
- Trial name
- FieldAI (NCT06796036)
- Testing
- Combat Medic Decision-Making with and without artificial intelligence assistance
- Where
- Czechia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Post Traumatic Stress Disorder
The Effects of Very Brief Exposure on PTSD in U.S. Combat Veterans
The goal of this clinical trial is to develop a new behavioral treatment for U.S. combat veterans with post-traumatic stress disorder (PTSD), very brief exposure to combat-related stimuli.
- Trial name
- PTSD (NCT06218381)
- Testing
- Very Brief Exposure to Combat Images
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Aging, Combat Disorders
Vietnam Era Health Retrospective Observational Study
The Vietnam Era Health Retrospective Observational Study (VE-HEROeS) is a national study on the health and well-being of Vietnam Veterans, including Blue Water Navy Veterans, as well as Veterans who served elsewhere during the…
- Trial name
- VE-HEROeS (NCT02825602)
- Where
- United States
- Volunteers
- 24,306 people
- Sponsor
- Veteran Affairs Office of Patient Care Services
PTSD - Post Traumatic Stress Disorder
Written Exposure Therapy Plus Adjunctive Methylphenidate Treatment for Veterans With PTSD
Many Veterans with post-traumatic stress disorder (PTSD) do not fully benefit from the best current treatments, some of which focus on helping the brain regulate trauma memories.
- Trial name
- WET+MPH (NCT07904000)
- Testing
- Written Exposure Therapy (WET), methylphenidate (MPH)
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- VA Office of Research and Development
Cardiac Arrest, Post Traumatic Stress Syndrome
Family-Authored ICU Diaries to Reduce Fear in Patients Experiencing a Cardiac Arrest (FAID Fear)
The present study will: Aim 1: Enroll 15 family members of CA patients to (a) pilot recruitment procedures, (b) estimate retention, and (c) assess acceptability of study procedures.
- Trial name
- FAID Fear (NCT05144477)
- Testing
- FAID Fear Intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Columbia University
PTSD - Post Traumatic Stress Disorder, Cardiac Arrest (CA)
Trial of Acceptance and Mindfulness-based Exposure Therapy (AMBET) and Present Centered Therapy (PCT)
The goal of this clinical trial is to learn if a new therapy called Acceptance- and Mindfulness-Based Exposure Therapy (AMBET) helps treat post-traumatic stress disorder (PTSD) in people who survived a cardiac arrest.
- Trial name
- NCT07410481
- Testing
- Acceptance and Mindfulness Based Exposure Therapy, Present-Centered Therapy
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Columbia University