Clinical trials: Combat
PTSD - Post Traumatic Stress Disorder
Written Exposure Therapy Plus Adjunctive Methylphenidate Treatment for Veterans With PTSD
Many Veterans with post-traumatic stress disorder (PTSD) do not fully benefit from the best current treatments, some of which focus on helping the brain regulate trauma memories.
- Trial name
- WET+MPH (NCT07904000)
- Testing
- Written Exposure Therapy (WET), methylphenidate (MPH)
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injuries
Telehealth-Education-Based Program for Military Caregivers of Injured Service Members With Head Injuries
The primary purpose of this research is to evaluate the impact of a telehealth-based, cognitive behavioral therapy (CBT) intervention (problem-solving training: PST) for adult informal military family/friend caregivers of OIF/OEF…
- Trial name
- NCT02215187
- Testing
- Problem-Solving Training (PST), Attention Control
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Vascular Injury
Survey of Tourniquet Use in a Combat Support Hospital
Data will be collected on the type of tourniquet and circumstances of its use. Patients with penetrating extremity injury will have clinical and pre-clinical hospital data collected.
- Trial name
- NCT00517166
- Testing
- CAT (Combat Arms Tourniquet)
- Where
- Iraq
- Volunteers
- 584 people
- Sponsor
- United States Army Institute of Surgical Research
PTSD - Post Traumatic Stress Disorder
Evaluating Evidenced Based Options for PTSD Treatment
This study will look at: How practical it is to offer another round of proven therapy. How effective different therapy options are for people who didn't respond to the first treatment.
- Trial name
- NCT06733376
- Testing
- Cognitive Processing Therapy, Prolonged Exposure, Skills Training for Affective and Interpersonal Regulation
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Rush University Medical Center
Posttraumatic Stress Disorder, Combat Disorders
An Open-Trial of Web-Prolonged Exposure (Web-PE) Among Active-Duty Military
It is urgent to make evidence-based treatments (EBTs) for military personnel readily accessible in order to meet the growing demand for effective and efficient treatment for posttraumatic stress disorder (PTSD) in a timely…
- Trial name
- NCT03337750
- Testing
- Web-PE Therapy
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of Pennsylvania
PTSD - Post Traumatic Stress Disorder, PTSD
Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder
The Redefine Study (COMP202) is testing COMP360 to see if it may reduce post-traumatic stress disorder (PTSD) symptoms when administered alongside monitoring and support from a trained study team.
- Conditions
- PTSD - Post Traumatic Stress Disorder, PTSD, PTSD Symptoms, PTSD, Post Traumatic Stress Disorder
- Trial name
- Redefine (NCT07570654)
- Testing
- COMP360 psilocybin
- Where
- 10 sites in United States, Canada
- Volunteers
- 300 people
- Sponsor
- COMPASS Pathways
TBI Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder
Veterans' Cognitive Function, Mental Health, and Quality of Life After Hyperbaric Oxygen Therapy
The purpose of this study is to evaluate how hyperbaric oxygen therapy (HBOT) may affect cognitive functioning, post-traumatic stress disorder (PTSD), depression, anxiety, and overall quality of life in veterans. 1.
- Conditions
- TBI Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Post Concussive Syndrome
- Trial name
- NCT07214415
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Summit Hyperbarics and Wellness
Hydration Education
Effect of Hydration Education on Young Judokas
Brief Summary The goal of this clinical trial is to learn whether a single-session hydration education intervention combined with hydration-promoting materials can improve hydration status in male child judo athletes (judokas)…
- Trial name
- NCT07897552
- Testing
- Hydration
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Combat Disorders, Stress Disorders, Post-Traumatic
A Placebo-Controlled Trial of D-Cycloserine and Exposure Therapy for Combat-PTSD
The primary aim of this project is to examine whether administration of D-Cycloserine (DCS), a partial N-methyl-D-aspartate (NMDA) receptor agonist that has been shown to facilitate fear extinction, enhances the therapeutic…
- Trial name
- NCT00371176
- Testing
- Exposure therapy, D-Cycloserine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- US Department of Veterans Affairs
Obesity
Virtual Sprouts: Web-based Gardening Games to Teach Nutrition and Combat Obesity
The purpose of this study is to develop, disseminate, and evaluate a web-based nutrition and gardening game using interactive, multiplatform and mobile gaming, rich narrative, a pedagogical agent, meaningful play, and…
- Trial name
- NCT02017158
- Testing
- Virtual Sprouts
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Iron Deficiency Anaemia, Stunting
Zambia Micronutrient Powder Trial Effectiveness Study
Addressing micronutrient deficiencies in Zambia is recognized as a national priority by the government due to its major contribution to morbidity and mortality among children, especially infants in their formative years.
- Trial name
- NCT01878734
- Testing
- Micronutrient Powders
- Where
- Zambia
- Volunteers
- 631 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Post-Traumatic Stress Disorder
Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD)
This was a six-week pilot study testing the efficacy of tramadol extended-release (ER) for posttraumatic stress disorder (PTSD).
- Trial name
- NCT01517711
- Testing
- Tramadol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Stress Disorders, Post-Traumatic
Image-guided, Robotically Delivered Transcranial Magnetic Stimulation Treatment for Combat-Related Post-Traumatic Stress Disorder
Mounting amounts of evidence suggests that non-invasive stimulation of the dorsolateral prefrontal cortex (DLPFC) using repetitive transcranial magnetic stimulation (rTMS) maybe a safe and effective treatment modality for…
- Trial name
- NCT02853032
- Testing
- Active repetitive transcranial magnetic stimulation, robotic arm
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Stress Disorders, Post-traumatic
Information Processing Modification in PTSD (Oct. 18)
The purpose of this study is to determine whether a computerized intervention designed to change the nature of attention biases will be effective in reducing the symptoms of post traumatic stress disorder (PTSD) in American…
- Trial name
- NCT00601952
- Testing
- Attention Bias Modification (ABM), Attention Control Condition (ACC)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- San Diego State University
Posttraumatic Stress Disorder, PTSD
Clinical Effectiveness Trial of In-Home Cognitive Processing Therapy for Combat-Related PTSD
The primary objective of this study is to evaluate the effectiveness of Cognitive Processing Therapy (cognitive only version; CPT-C) delivered using two different formats in the home setting for the treatment of combat-related…
- Trial name
- NCT02290847
- Testing
- Cognitive Processing Therapy (cognitive only version; CPT-C)
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Moral Injury, Functional Impairment
Consulting After Combat: Interviewing Veterans to Develop a Therapy to Restore Functioning and Reintegration After Moral Injury Events
Despite the VA's best efforts to treat the psychosocial impact of war, many combat Veterans report lingering difficulty reintegrating into meaningful post-deployment lives.
- Trial name
- CAC (NCT05020587)
- Testing
- Open pilot trial of a group therapy manual.
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress Disorders
Evaluation of Telehealth Interventions for Post-Trauma Stress
Posttraumatic Stress Disorder (PTSD) is very prevalent within the veteran population and is associated with decreased quality of life and an increased risk of developing other psychiatric and physical illnesses.
- Trial name
- NCT00350584
- Testing
- Mindfulness Telehealth Intervention, Psychoeducation Telehealth Intervention
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- VA Boston Healthcare System
Pediatric Obesity
Integrating Community LITE Programme as an Online Family-based Intervention to Combat Childhood Obesity
Childhood obesity in Singapore is rising with a record prevalence of 13% in 2017 (1). Given that 70% of overweight children remain so into adulthood (2), this will further increase the public health epidemic of diabetes among…
- Trial name
- NCT05281016
- Testing
- Usual Care, Online community LITE programme
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Anxiety Disorders, Complex Regional Pain Syndrome Type II
Regional Anesthesia Military Battlefield Pain Outcomes Study
The purpose of this study is to examine the short and long-term benefits of implementing early regional anesthesia techniques for pain control after a major traumatic injury to one or more extremities during combat in the…
- Conditions
- Anxiety Disorders, Complex Regional Pain Syndrome Type II, Depressive Disorders, Post-Traumatic Stress Disorder
- Trial name
- RAMBPOS (NCT00431847)
- Testing
- Regional Anesthesia, Standard Pain Management Protocol
- Where
- 3 sites in United States
- Volunteers
- 386 people
- Sponsor
- VA Office of Research and Development
Mood Disorders, Depression
Effects of Omega-3 EPA/DHA for Soldiers at Risk for Mood Disorders
Stress-related disorders are among the most prevalent and expensive medical consequences of participation in military operations.
- Conditions
- Mood Disorders, Depression, Combat Disorders, Stress Disorders
- Trial name
- NCT01216982
- Testing
- Lovaza, omega-3 fatty acid ethyl ester
- Where
- Iraq
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- United States Department of Defense