Clinical trials: Combat
Combat Stress Disorder
Exploring Deployment Stress and Reintegration in Army National Guard Chaplains
The purpose of this 2-year pilot study is to explore the impact of deployment on the psychosocial and health characteristics and reintegration of Military Chaplains, specifically those of the Army National Guard (ARNG).
- Trial name
- NCT01330888
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Traumatic Brain Injury
Brain Training to Enhance Frontal Lobe Reasoning
This study is being done to improve the ability to diagnose and to achieve higher-levels of functional recovery in soldiers and civilians who have suffered either mild Traumatic Brain Injury (TBIs) or moderate-to-severe TBIs at…
- Trial name
- NCT01552473
- Testing
- Brain Training Program 1, Brain Training Program 2
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- The University of Texas at Dallas
Stress Disorders, Post Traumatic
A Trial of "Coping Coach," a Web-based Preventive Intervention for Children
This study will evaluate the impact of a psychosocial intervention, Coping Coach, delivered online to children who have experience an acute medical event.
- Trial name
- NCT01653288
- Testing
- Coping Coach
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Children's Hospital of Philadelphia
Medication Adherence, HIV/AIDS
A Mobile Gaming App to Improve Adherence to PrEP
In this study, the investigators will test the mobile game, Viral Combat, for efficacy and acceptability among diverse participants, ages 15-34 years, receiving PrEP care in clinical settings in New England and Mississippi.
- Trial name
- NCT05762705
- Testing
- Multilevel Gaming Adherence Intervention, Treatment as Usual +
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Trauma, Wounds and Injuries
Registry of Emergency Airways Arriving at Combat Hospitals
This represents the first prospective examination of advanced airway management under combat conditions. The findings will have a tremendous impact on both modern prehospital medical practice and on the treatment of our wounded…
- Conditions
- Trauma, Wounds and Injuries, Emergencies
- Trial name
- REACH (NCT01405001)
- Volunteers
- 292 people
- Sponsor
- William Beaumont Army Medical Center
PTSD - Post Traumatic Stress Disorder
Brief Exposure and Exercise for PTSD.
The goal of this clinical trial is to learn if 8 sessions of brief exposure and exercise therapy works to treat Post Traumatic Stress Disorder (PTSD) in adults.
- Trial name
- BEE for PTSD (NCT07080606)
- Testing
- Brief exposure therapy and exercise
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Troy Hubert
Methicillin-resistant Staphylococcus Aureus, Clostridium Difficile
Animal-Assisted Visitation Program Chlorhexidine Trial
Hospital-based Animal-Assisted visitation programs are important complementary therapies, but concerns with infection control may challenge the sustainability of these programs.
- Conditions
- Methicillin-resistant Staphylococcus Aureus, Clostridium Difficile, Pseudomonas Aeruginosa
- Trial name
- NCT04171817
- Testing
- Chlorhexidine
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Stress Disorders, Post-Traumatic, Sleep Initiation and Maintenance Disorders
Examining the Effect of Acupuncture on Sleep Difficulties Related to Post Traumatic Stress Disorder
The purpose of this study was to examine if group ear acupuncture improves Post-Traumatic Stress Disorder sleep difficulties among veterans who participated in Operations Enduring Freedom and Iraqi Freedom.
- Trial name
- NCT00868517
- Testing
- True group auricular acupuncture, Wait-List Control Group
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- US Department of Veterans Affairs
PTSD - Post Traumatic Stress Disorder
Propranolol for Early Secondary Prevention of Post-Traumatic Stress Disorder in Women Victims of Sexual Violence
The goal of this clinical trial is to evaluate the effect of early propranolol administration on the occurrence of post-traumatic stress disorder (PTSD) symptoms at five weeks in adult female victims of sexual violence.
- Trial name
- PPRESVISE (NCT07452978)
- Testing
- Propranolol, 120mg
- Volunteers
- 34 people
- Sponsor
- University Hospital, Tours
Trauma
Dexamethasone as an Immediate Intervention
To determine if a single dose of dexamethasone (5 mg) administered in the first 12 hours following a potentially traumatic event alters a) cortisol and FKBP5 RNA the next day in the periphery measured in saliva; b) FKBP5…
- Trial name
- NCT02753166
- Testing
- Dexamethasone
- Where
- United States
- Sponsor
- NYU Langone Health
Stress Disorders, Combat Disorders
FOCUS-CI: A Preventive Intervention With Children and Families of the Combat Injured
The purpose of this study is to implement a unique evidence-based intervention program to help military families deal with the critical issue of combat injury and its impact on current and future family health and functioning.
- Conditions
- Stress Disorders, Combat Disorders, Traumatic Stress Disorders
- Trial name
- FOCUS-CI (NCT01062022)
- Testing
- Standard of Care, FOCUS-CI
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Exercise Adaptation, Aerobic Capacity
AEROBIC ADAPTATION AND BIOMARKER RESPONSES IN COMBAT ATHLETES
This randomized controlled study investigates the effects of sport-specific training on aerobic adaptation and circulating biomarker responses in trained combat athletes.
- Conditions
- Exercise Adaptation, Aerobic Capacity, Athletic Performance, Combat Sports Training
- Trial name
- AERO-BIO (NCT07473440)
- Testing
- SPORT-SPECIFIC CONDITIONING PROGRAM
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Posttraumatic Stress Disorder
Variable-length Cognitive Processing Therapy for Combat-Related PTSD
The primary goal of this study is to improve the overall efficacy of cognitive processing therapy-cognitive-only version (CPT-C) in a sample of 130 active-duty service members through a variable length treatment.
- Trial name
- NCT02313818
- Testing
- Cognitive Processing Therapy-Cognitive Only
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Duke University
Posttraumatic Stress Disorder
Deep Brain Stimulation of the Amygdala for Combat Post-Traumatic Stress Disorder
Posttraumatic stress disorder (PTSD) affects approximately 30 % of American veterans returning from Iraq and Afghanistan. Although the current therapy is effective, a percentage of patients will fail to improve and will develop…
- Trial name
- NCT02091843
- Testing
- DBS of the Basolateral Nucleus of the Amygdala, Medtronic Activa PC DBS of the Basolateral Nucleus of the Amygdala
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Post Traumatic Stress Disorder, Combat Stress Disorders
MDMA-Assisted Psychotherapy in Veterans With Combat-Related, Refractory PTSD
This will be a single-site, open-label phase 2 study designed to test the feasibility of administering MDMA in conjunction with psychotherapy for combat-related treatment-resistant PTSD in US military veterans currently enrolled…
- Trial name
- VALLMDMA_001 (NCT04264026)
- Testing
- 3,4-methylenedioxymethamphetamine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Loma Linda Health Care System
Post-Traumatic Stress Disorder, PTSD
Trauma-informed Psilocybin Assisted Psychotherapy (TiPAP) for PTSD
This is an open-label pilot study designed to evaluate the safety, tolerability, and preliminary clinical effects of psilocybin-enhanced trauma-focused psychotherapy in individuals with post-traumatic stress disorder (PTSD).
- Trial name
- TiPAP-PTSD (NCT07737054)
- Testing
- Psilocybin (drug), Trauma-Focused Psychotherapy
- Where
- Israel
- Volunteers
- 13 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Suicide Prevention
Suicide in Urban Natives: Detection and Networks to Combat Events
This study compares the effectiveness of a program to detect and manage suicide risk among American-Indian and Alaska Native (AI/AN) youth.
- Trial name
- SUNDANCE (NCT03136094)
- Testing
- SBIRT+12, SBIRT+Usual Care
- Where
- United States
- Volunteers
- 698 people
- Sponsor
- University of Colorado, Denver
PTSD - Post Traumatic Stress Disorder
MentalGym™ and NeuroBrave™ Guided Wearable-Assisted Physiology Regulation Training for PTSD (PRTP)
This randomized controlled trial (RCT) will evaluate the effectiveness of a digital biofeedback-based intervention ("Mental Gym®") designed to reduce Posttraumatic Stress Disorder (PTSD) symptoms and improve mental health.
- Trial name
- NCT07462312
- Testing
- Mental Gym® Biofeedback System
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- NeuroBrave ltd.
Post Traumatic Stress Disorder PTSD
Nurse-Led PTSD Treatment in Primary Care
Purpose of the Study Post-traumatic stress disorder (PTSD) is a common and serious condition, but many people cannot get the help they need because there are not enough mental health specialists (like psychologists or…
- Trial name
- NCT07430657
- Testing
- NurseNET, Referral to PTSD Treatment
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Rush University Medical Center
Opioid Use Disorder, Intimate Partner Violence (IPV)
Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and Recovery
Using a hybrid type 1 effectiveness-implementation approach, this study aims to evaluate the impact of a novel stepped care model ("PCT+2HOPE") versus treatment as usual (TAU) on increasing retention in community-based medication…
- Conditions
- Opioid Use Disorder, Intimate Partner Violence (IPV), Post Traumatic Stress Disorder PTSD
- Trial name
- STRONGER (NCT07115030)
- Testing
- PCT+2HOPE
- Where
- 3 sites in United States
- Volunteers
- 532 people
- Sponsor
- Yale University