Clinical trials: Combat
Post-Traumatic Stress Disorder, PTSD
Trauma-informed Psilocybin Assisted Psychotherapy (TiPAP) for PTSD
This is an open-label pilot study designed to evaluate the safety, tolerability, and preliminary clinical effects of psilocybin-enhanced trauma-focused psychotherapy in individuals with post-traumatic stress disorder (PTSD).
- Trial name
- TiPAP-PTSD (NCT07737054)
- Testing
- Psilocybin (drug), Trauma-Focused Psychotherapy
- Where
- Israel
- Volunteers
- 13 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Metastatic Pancreatic Adenocarcinoma
Study Assessing Safety and Efficacy of Combination of BL-8040 and Pembrolizumab in Metastatic Pancreatic Cancer Patients
This study will assess the efficacy and safety of BL-8040 in combination with pembrolizumab (Keytruda®) and BL-8040/ Pembrolizumab in combination with liposomal irinotecan (Onivyde®)/5-fluorouracil/leucovorin (5-FU/LV) in…
- Trial name
- COMBAT (NCT02826486)
- Testing
- BL-8040, Pembrolizumab, Chemotherapy
- Where
- 31 sites in United States, Israel and 2 more
- Volunteers
- 80 people
- Sponsor
- BioLineRx, Ltd.
Post Traumatic Stress Syndrome
The Effects of D-cycloserine on Stimulus Generalization of Conditioned Fear Healthy Controls.
PROJECT SUMMARY: PTSD is a debilitating psychiatric condition precipitated by exposure to extreme, or life threatening, trauma with an estimated lifetime prevalence between 8% and 9% in U.S. adults.
- Trial name
- DCS (NCT01733030)
- Testing
- Seromycin
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Nutrition, Healthy
The Effect of Omega-3 Fortified Smoothies on Omega-3 Index and Physical Performance Related Outcomes Among Soldiers
The goal of this clinical trial is to test the effect of omega-3 on physical performance and recovery of Soldiers. Objectives 1: Assess the impact of 8-weeks of daily consumption of 1600mg of omega-3 fortified smoothie on O3I…
- Trial name
- H2FO3 (NCT06462898)
- Testing
- Omega-3 Fortified Protein Smoothie, Non-Fortified Protein Smoothie
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Post Traumatic Stress Disorder PTSD
Psychosocial Factors and Efficacy of Remote Cognitive Remediation for Post-Traumatic Stress Disorder
The goal of this clinical trial is to evaluate whether computer-based brain training can help adults with post-traumatic stress disorder (PTSD).
- Trial name
- NCT07309302
- Testing
- Cognitive Remediation Training, Control Group
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Université du Québec a Montréal
Obesity, Overweight
NEW Keiki Family Based Intervention to Combat Childhood Obesity
The purpose of this project is to create a database to collect information about the NEW Keiki Program. The information collected for this project will be used to evaluate the program.
- Trial name
- NCT02691039
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Malia Shimokawa, MD
PTSD - Post Traumatic Stress Disorder, Sexual Abuse
Evaluation of Restory - an Online Trauma Treatment for Victims of Sexual Abuse
This project aims to evaluate Restory - a newly developed anonymous, iCBT prolonged exposure therapy program specifically tailored for victims of sexual abuse - using a pre-registered randomized controlled trial with waitlist…
- Trial name
- NCT07610187
- Testing
- Restory
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Karolinska Institutet
PTSD - Post Traumatic Stress Disorder, PTSD and Alcohol Use Disorder
Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons
Addiction and trauma exposure are common among the 5.5 million people (1 in 47 adults) in the U.S. who are in prison or under supervision.
- Conditions
- PTSD - Post Traumatic Stress Disorder, PTSD and Alcohol Use Disorder, PTSD and Trauma-related Symptoms, Substance Use Disorder (SUD)
- Trial name
- STRIDES2 (NCT06923423)
- Testing
- Group Cognitive Processing Therapy (CPT), Control Group Individual trauma focused self-help via workbook
- Where
- 6 sites in United States
- Volunteers
- 640 people
- Sponsor
- University of Arkansas
Squamous Cell Carcinoma of Head and Neck
Using MASL to Combat Oral Cancer
This project will evaluate the expression of a receptor called podoplanin (PDPN) in cells from oral cancers and precancerous lesions.
- Trial name
- NCT04188665
- Testing
- MASL
- Where
- 4 sites in United States
- Volunteers
- 18 people
- Sponsor
- Rowan University
Post Traumatic Stress Disorder PTSD, Major Depressive Disorder (MDD)
Accelerated iTBS for PTSD and Depression
The goal of this pilot clinical trial is to learn if a faster brain stimulation schedule is practical, safe, tolerable, and acceptable. This study looks at accelerated intermittent theta burst stimulation, or accelerated iTBS.
- Trial name
- NCT07682207
- Testing
- Accelerated intermittent theta burst stimulation
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Lawson Research Institute of St. Joseph's
Concussion Post Syndrome, Concussion
Effect of Vestibular Rehabilitation on Gait, Balance, and Coordination in Post Concussion Combat Athletes
This randomized controlled trial aims to evaluate the effectiveness of vestibular rehabilitation in improving gait and balance among post-concussion combat athletes aged 18-25 years.
- Trial name
- NCT07717528
- Testing
- Vestibular Rehabilitation Program, Conventional Post-Concussion Rehabilitation
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Posttraumatic Stress Disorder, Combat Disorders
An Open-Trial of Web-Prolonged Exposure (Web-PE) Among Active-Duty Military
It is urgent to make evidence-based treatments (EBTs) for military personnel readily accessible in order to meet the growing demand for effective and efficient treatment for posttraumatic stress disorder (PTSD) in a timely…
- Trial name
- NCT03337750
- Testing
- Web-PE Therapy
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of Pennsylvania
Post-traumatic Stress Disorder (PTSD)
Blended Trauma-Focused Cognitive Behavioral Therapy With Compassion
Brief Summary The goal of this clinical trial is to evaluate the feasibility and acceptability of a blended (mHealth) Trauma-Focused Cognitive Behavioral Therapy with Compassion (bTF-CBT-C) for adolescents with post-traumatic…
- Trial name
- b-TF-CBT-C (NCT07407946)
- Testing
- Blended Trauma-Focused Cognitive Behavioral Therapy with Compassion (bTF-CBT-C), Trauma-Focused Cognitive Behavioral Therapy (TF-CBT)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Umeå University
Cardiac Autonomic Function, Hemodynamic Changes
Effects of Post-Match Foam Rolling, Static Stretching, and Passive Rest on Acute Cardiac-Autonomic, Hemodynamic, and Neuromuscular Recovery in National Wrestlers
This study looks at three common ways athletes recover after a wrestling match: foam rolling, static stretching, and resting. We want to learn which method helps the body recover better in the short time that athletes often have…
- Conditions
- Cardiac Autonomic Function, Hemodynamic Changes, Neuromuscular Adaptations, Exercise and Recovery
- Trial name
- NCT07305506
- Testing
- Foam Rolling, Static Stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ali Kamil GÜNGÖR
Post Traumatic Stress Disorder PTSD
Inhaled Cannabis for Treatment of PTSD
The rationale for the use of inhalational cannabis to potentially treat PTSD symptoms is based on the many reports of cannabis attenuating PTSD symptom expression among individuals with PTSD, including veterans.
- Trial name
- NCT07224698
- Testing
- High THC Cannabis
- Volunteers
- 320 people
- Sponsor
- Multidisciplinary Association for Psychedelic Studies
PTSD - Post Traumatic Stress Disorder
Brief Exposure and Exercise for PTSD.
The goal of this clinical trial is to learn if 8 sessions of brief exposure and exercise therapy works to treat Post Traumatic Stress Disorder (PTSD) in adults.
- Trial name
- BEE for PTSD (NCT07080606)
- Testing
- Brief exposure therapy and exercise
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Troy Hubert
Bloodstream Infection
Comparison of Bloodstream Infections With Carbapenem Hetero-resistant vs Carbapenem Resistant Klebsiella Pneumoniae
COMBAT trial was contemplated to elucidate unknown clinical relevance of carbapenem heteroresistance among Klebsiella pneumoniae species.
- Trial name
- COMBAT (NCT04229498)
- Testing
- Monotherapy and combination therapy (all antibiotics that are given by attending pysicians and can be active against Klebsiella pneumoniae will be evaluated)
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- SCARE (Study group for carbapenem resistance)
Personality Disorder, Borderline, Personality Trait
Bridging Affect Consciousness, Mentalization and Trauma- Exploring an Integrative Treatment Approach for Personality Disorder (PD).
Study background: Specialized Group Outpatient Clinic within specialist mental health services, tailoring two year group treatment programmes for severe Avoidant PD (AvPD) and Borderline PD (BPD) with Affect Consciousness (AC)…
- Conditions
- Personality Disorder, Borderline, Personality Trait, Personality Disorder, Personality Type
- Trial name
- NCT06983002
- Testing
- Experimental group: AC-group therapy intervention., Control group 1: Body Awareness Group., Control group 2: Art Psychotherapy group.
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Helse Stavanger HF
Psychological Trauma
Virtual Reality and D-Cycloserine in Combat Related Psycological Trauma in Burn Service Members
The purpose of this pilot study is to begin the examination of the feasibility of using Gradual Virtual Reality Exposure Therapy and D-Cycloserine (DCS) in the management of posttraumatic psychological symptoms in burned OIF/OEF…
- Trial name
- NCT00855153
- Testing
- VR (Virtual reality), D-Cycloserine
- Where
- United States
- Sponsor
- United States Army Institute of Surgical Research
Post Traumatic Stress Disorder PTSD
The Effects of Stellate Ganglion Block Sleep in U.S. Active Duty Service Members and Veterans Receiving Prolonged Exposure Therapy for PTSD
Participants in this study will have already been enrolled in another research study: Combining Stellate Ganglion Block with Prolonged Exposure for PTSD, NCT05889741.
- Trial name
- NCT07667309
- Testing
- Sleep Profiler Headband
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center at San Antonio