Clinical trials: Combat
PTSD, Post Traumatic Stress Disorder
Massed Cognitive Processing Therapy for Combat-related PTSD
The purpose of this study is to determine if cognitive processing therapy (CPT) delivered in a massed format (MCPT) is as effective as standard delivery of CPT.
- Trial name
- NCT03808727
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- VA Boston Healthcare System
Blast or Combat Exposure, Head Injury Trauma
Pre-post Evaluation of the Safety and Efficacy of Ibogaine-Magnesium Therapy in Veterans With Repeated Blast Exposure
A Pre-post Study Evaluating the Safety and Efficacy of Ibogaine-Magnesium Therapy in Veterans with Sequelae of Repeated Blast Exposure.
- Trial name
- NCT04313712
- Testing
- ibogaine with magnesium treatment
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Posttraumatic Stress Disorder
Prolonged Exposure Versus Treatment as Usual in Chronic Posttraumatic Stress Disorder Combat and Terror Related Patients
Assessing the efficacy of Posttraumatic Stress Disorder (PE) treatment for chronic Posttraumatic Stress Disorder (PTSD)
- Trial name
- NCT00229372
- Testing
- Prolonged Exposure (PE) therapy
- Where
- Israel
- Sponsor
- Sheba Medical Center
Post Traumatic Stress Disorder PTSD
Effectiveness of Informational and Educational Tools to Improve the Experience of Relatives of ICU Patients. RELIEF, a Platform Trial
The admission of a patient to an intensive care unit (ICU) is associated with high levels of acute stress, anxiety, and depression among relatives, as well as extreme emotions such as fear, guilt, distress, and helplessness.
- Trial name
- RELIEF (NCT06851884)
- Testing
- Standard of Care (SOC), Video capsules, Cartoon
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post Traumatic Stress Disorder PTSD
Developing Innovative PTSD Treatment for Children
This study is testing a new version of a treatment called the Reconsolidation of Traumatic Memories Protocol for Children (RTM-C Protocol).
- Trial name
- ChildrenRTM (NCT07185126)
- Testing
- Reconsolidation of traumatic memories
- Where
- Ukraine
- Volunteers
- 40 people
- Sponsor
- Viktoriia Gorbunova
Combat Disorders, Stress Disorders, Post-Traumatic
A Placebo-Controlled Trial of D-Cycloserine and Exposure Therapy for Combat-PTSD
The primary aim of this project is to examine whether administration of D-Cycloserine (DCS), a partial N-methyl-D-aspartate (NMDA) receptor agonist that has been shown to facilitate fear extinction, enhances the therapeutic…
- Trial name
- NCT00371176
- Testing
- Exposure therapy, D-Cycloserine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- US Department of Veterans Affairs
PTSD, Recent Era Combat Veteran
UCLA Couples Counseling for Combat Veterans
A pilot intervention of an existing intervention adapted for the returning warfighter population: a couples treatment for PTSD, Structured Approach Therapy (SAT), which emphasizes reducing the PTSD avoidance/numbing symptoms that…
- Conditions
- PTSD, Recent Era Combat Veteran, Couples Communication
- Trial name
- CCCV (NCT01627548)
- Testing
- Structured Approach Therapy
- Where
- United States
- Sponsor
- University of California, Los Angeles
PTSD, Post Traumatic Stress Disorder
Targeted Plasticity Therapy for PTSD
Objectives of this study are to provide continued safety assessment for the ReStore system, and to gain further estimates of the effect size of Vagus Nerve Stimulation (VNS) therapy with Prolonged Exposure Therapy (PE) compared…
- Trial name
- NCT06266364
- Testing
- Active VNS stimulation
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas at Dallas
Obsessive Compulsive Disorder (OCD), Bipolar Disorders
Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions
This is a research study looking at whether the way people speak can help predict how well they'll respond to certain mental health treatments.
- Conditions
- Obsessive Compulsive Disorder (OCD), Bipolar Disorders, Major Depressive Disorder, Post-Traumatic Stress Disorder, PTSD
- Trial name
- NCT06823024
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Psyrin Inc.
Mood Disorders, Depression
Effects of Omega-3 EPA/DHA for Soldiers at Risk for Mood Disorders
Stress-related disorders are among the most prevalent and expensive medical consequences of participation in military operations.
- Conditions
- Mood Disorders, Depression, Combat Disorders, Stress Disorders
- Trial name
- NCT01216982
- Testing
- Lovaza, omega-3 fatty acid ethyl ester
- Where
- Iraq
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- United States Department of Defense
Wound Heal
Efficacy of SynEx Wound Rinse in Civilian Surrogates of Combat Injury Wounds
The purpose of this interventional study is to compare SynEx Wound Cleanser with the current routine care (Saline) in traumatic wounds.
- Trial name
- NCT05743283
- Testing
- SynEx Wound Cleanser, Saline
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Synedgen, Inc.
Posttraumatic Stress Disorder
Modafinil in the Treatment of PTSD (Posttraumatic Stress Disorder)
The purpose of this study is to determine if modafinil is more effective than placebo in the treatment of posttraumatic stress disorder (PTSD) in male combat veterans who have been deployed to Iraq or Afghanistan.
- Trial name
- NCT01726088
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Biomedical Research Foundation
Post-Traumatic Stress Disorder
Carvedilol Versus Placebo for Treatment in Post Traumatic Stress Disorder (PTSD)
The investigators hypothesize that carvedilol, at less then therapeutic doses for cardiac effect, will reduce symptoms of Post Traumatic Stress Disorder.
- Trial name
- NCT01221792
- Testing
- Carvedilol
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Columbia Northwest Pharmaceuticals
PTSD, Suicidal Ideation
Experiential Avoidance in Combat Veterans With and Without Posttraumatic Stress Disorder
This study plans to examine if symptoms of PTSD affect how Veterans who have served in combat think and react to certain information, and whether or not this has an influence on suicidal thoughts.
- Trial name
- NCT01652430
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Traumatic Brain Injury
Brain Training to Enhance Frontal Lobe Reasoning
This study is being done to improve the ability to diagnose and to achieve higher-levels of functional recovery in soldiers and civilians who have suffered either mild Traumatic Brain Injury (TBIs) or moderate-to-severe TBIs at…
- Trial name
- NCT01552473
- Testing
- Brain Training Program 1, Brain Training Program 2
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- The University of Texas at Dallas
Chronic Pain Due to Injury, Neuroma of Lower Limb
Botulinum Toxin Type A Versus Local Anesthetic Injection for Chronic Neuroma Pain After Combat-Related Amputation
Patients with combat-related amputations frequently experience persistent neuroma pain that may interfere with rehabilitation, prosthesis use, sleep, mobility, and quality of life.
- Conditions
- Chronic Pain Due to Injury, Neuroma of Lower Limb, Neural Injury, Neuroma of Upper Limb
- Trial name
- NEUROQUIET (NCT07626983)
- Testing
- Botulinum Toxin Type A (BoNT-A), Local Anesthetic Solution
- Where
- 2 sites in Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Cellulite
Structural Changes of Subcutaneous Tissue by Ultrasonographies in Patients After Treatment With PnKCelulitis® Program
Exploratory, prospective, uncontrolled and single-blinded pilot study, with clinical and ultrasound assessments of cutaneous cellulite before and after treatment with a specific multidisciplinary programme following dietary…
- Trial name
- PnKCelulitis (NCT03550157)
- Volunteers
- 20 people
- Sponsor
- Protein Supplies SL
Posttraumatic Stress Disorder
Hypnotherapeutic Olfactory Conditioning for Posttraumatic Stress Disorder (PTSD)
Chronic combat-related posttraumatic stress disorder can be difficult to treat. The investigators believe that hypnosis, with a stress on the sensation of scent which often plays a role in the traumatic memories, can offer help…
- Trial name
- NCT00784771
- Testing
- Hypnotherapeutic Olfactory Conditioning (HOC)
- Where
- Israel
- Volunteers
- 36 people
- Sponsor
- Herzog Hospital
Iron Deficiency Anaemia, Stunting
Zambia Micronutrient Powder Trial Effectiveness Study
Addressing micronutrient deficiencies in Zambia is recognized as a national priority by the government due to its major contribution to morbidity and mortality among children, especially infants in their formative years.
- Trial name
- NCT01878734
- Testing
- Micronutrient Powders
- Where
- Zambia
- Volunteers
- 631 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Stress Disorders, Post-traumatic
Information Processing Modification in PTSD (Oct. 18)
The purpose of this study is to determine whether a computerized intervention designed to change the nature of attention biases will be effective in reducing the symptoms of post traumatic stress disorder (PTSD) in American…
- Trial name
- NCT00601952
- Testing
- Attention Bias Modification (ABM), Attention Control Condition (ACC)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- San Diego State University