Clinical trials: Common Bile Duct Diseases
Irritable Bowel Syndrome, Gallstone Disease
Pharmacokinetics, Bioequivalence, and Safety Study of Trimedat® 76,95 mg Orally Disintegrating Tablets and Trimedat® 100 mg Tablets in Healthy Volunteers.
This study aims to evaluate pharmacokinetic profile, safety and establish bioequivalence of the investigational drug Trimedat® 76,95 mg orally disintegrating tablets compared to the reference drug Trimedat® 100 mg tablets in…
- Conditions
- Irritable Bowel Syndrome, Gallstone Disease, GERD, Biliary Dyskinesia
- Trial name
- NCT07421011
- Testing
- Trimedat®
- Where
- Russia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Cholelithiasis, Biliary Dyskinesia
Natural Orifice Translumenal Endoscopic Surgery (NOTES) Transvaginal Cholecystectomy
Natural Orifice Translumenal Endoscopic Surgery (NOTES) describes a new field of investigational surgery which uses the endoscope as the primary operative tool.
- Trial name
- NCT00984100
- Testing
- NOTES Transvaginal Cholecystectomy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Baystate Medical Center
Drainage, Laparoscopic Cholecystectomy
The Efficacy and Safety of Using Prophylactic Abdominal Drainage After Cholecystectomy
Investigators want to assess the safety and efficacy of using abdominal drainage with not using any drainage, by estimating different outcomes after laparoscopic cholecystectomy for different reasons.
- Conditions
- Drainage, Laparoscopic Cholecystectomy, Acute Cholecystitis
- Trial name
- NCT05267860
- Testing
- Prophylactic Drain
- Where
- Syria
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Cholelithiasis Associated With Common Bile Duct Stones
Timing of Laparoscopic Cholecystectomy After Endoscopic Retrograde Cholangiography for Acute Biliary Pancreatitis
Timing of laparoscopic cholecystectomy following after endoscopic retrograde cholangiography for acute biliary pancreatitis is a controversial issue.
- Trial name
- NCT01687959
- Testing
- tissue sampling from peritoneum of the gallbladder
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Chronic Cholecystitis, Biliary Dyskinesia
Food-Effect, Single and Multiple Dose Pharmacokinetics, Safety and Tolerability Study of 4-MUST, 128 mg, Tablets in Healthy Volunteers
This open-label study will evaluate the effect of food on the bioavailability of a single dose of 4-MUST, tablets, 128 mg. Additionally, the study will assess the pharmacokinetics, safety, and tolerability of 4-MUST, tablets, 128…
- Trial name
- NCT07594977
- Testing
- 4-MUST
- Where
- Russia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Choledocholithiasis, Asymptomatic Condition
The Treatment Effect for Asymptomatic Common Bile Duct Stone
This study is prospective, multicenter study for identify the characteristics of asymptomatic common bile duct stones and effectiveness of treatment.
- Conditions
- Choledocholithiasis, Asymptomatic Condition, Quality of Life
- Trial name
- NCT06215040
- Testing
- Endoscopic retrograde cholangiopancratography
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Hospital
Cholecystitis, Cholelithiasis
Feasibility and Utility of Artificial Intelligence (AI) / Machine Learning (ML) - Driven Advanced Intraoperative Visualization and Identification of Critical Anatomic Structures and Procedural Phases in Laparoscopic Cholecystectomy
The goal of this study is to evaluate the utility and efficacy of an artificial intelligence (AI) model at identifying structures and phases of surgery compared to traditional white light assessment by trained surgeons.
- Conditions
- Cholecystitis, Cholelithiasis, Biliary Dyskinesia
- Trial name
- NCT05775133
- Testing
- ICG
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Activ Surgical
Choledocholithiasis
To Compare EUS and MRCP in Detecting Choledocholithiasis in Patients of Intermediate Risk of Choledocholithiasis
A Recent Meta analysis, showed pooled sensitivity and specificity were 97% and 90 for EUS and 87% and 92 for MRCP . This meta analysis includes only 5 studies, smaller sample size in each study, significant heterogeneity in…
- Trial name
- NCT04173624
- Testing
- Endosonography, Magnetic Resonance Cholangiopancreatography
- Where
- India
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Cholelithiasis, Common Bile Duct
Intraoperative ERCP Versus Therapeutic Splitting in Cholecysto-, Choledocholithiasis
At the Kepler University Hospital Linz all variants of ERCP (preoperative, intraoperative, postoperative ERCP) are performed in cases of simultaneous cholecysto- and choledocholithiasis.
- Trial name
- NCT06130163
- Testing
- endoscopic retrograde cholangiopancreatography
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kepler University Hospital
Chronic Pancreatitis, Chronic Pain
QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing
Quantitative Sensory Testing (QST) is a novel investigative technique used in other pain conditions to evaluate patterns of chronic pain, and in this study will be used to elucidate pain patterns in patients with Chronic…
- Trial name
- NCT03434392
- Testing
- Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Anna Evans Phillips
Common Bile Duct Calculi
Failed Retrograde Cholangiopancreatography (ERCP) Stone Extraction: Surgical Interference
Assessment of the differences in stone size and the largest CBD diameter before and after stenting in one or two sessions. Stone clearance and complications were also determined with the ERCP, and factors associated with complete…
- Trial name
- NCT05746832
- Testing
- Endoscopic stenting Retrograde Cholangiopancreatography (ERCP)
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Assiut University
Common Bile Duct Closure
Comparative Study of Three Common Bile Duct Closure Techniques
This study evaluates the efficacy and safety of three different methods of CBD repair after common bile duct exploration and provides more evidence for selecting the optimal duct closure after choledocholithotomy.
- Trial name
- NCT04264299
- Testing
- T tube drainage, Primary closure, Antegrade stenting
- Where
- Egypt
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- South Valley University
Common Bile Duct Gallstones
Effect of Saline Irrigation to DEcrease Rate Of Residual Common Bile Duct Stones
In recent years, endoscopic sphincterotomy and stone extraction are standard procedures for the removal of bile duct stones. After procedures, there are some complications such as stone recurrence, papillary stenosis, cholangitis…
- Trial name
- SIDEROD (NCT01425177)
- Testing
- Normal Saline Irrigation
- Where
- South Korea
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Choledocholithiasis
Papillary Balloon Dilation Versus Intraductal Lithotripsy
Our aim is to compare the efficacy, safety, procedural time required, and costs of a strategy initially employing cholangioscopy guided intraductal lithotripsy (laser/electrohydraulic lithtripsy (EHL)) versus a strategy initially…
- Trial name
- NCT03536247
- Testing
- Initial therapy with papillary balloon dilation, Initial therapy with intraductal lithotripsy
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Sphincter of Oddi Dysfunction
A Study of Serial Magnetic Resonance Cholangiopancreatography (MRCP) Following Morphine-neostigmine and Secretin Provocation in Healthy Volunteers
The sphincter of Oddi is a circular band of muscle which controls the flow of pancreatic juices and bile into the small intestine.
- Trial name
- NCT01134848
- Testing
- Morphine, Neostigmine, 0.9% saline
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Choledocholithiasis
EUS Guided ERCP in Bile Duct Stone Removal
For endoscopist, ERCP for bile duct stone removal is the most widely performed procedure. However, the risk associated radiation exposure to patients and staff are not neglible.
- Trial name
- NCT02870686
- Testing
- ERCP without the use of fluoroscopy, ERCP with the use of fluoroscopy
- Where
- Thailand
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University