Clinical trials: Communication Disorders
Primary Progressive Aphasia(PPA)
Speech and Language Interventions for Italian People With PPA
Primary progressive aphasia (PPA) is an umbrella term used to refer to several clinical variants that manifest as an insidious deterioration of speech/language skills, usually due to frontotemporal lobar degeneration and/or…
- Trial name
- PPA-rehab (NCT06739967)
- Testing
- Behavioral Treatment
- Where
- 2 sites in Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Developmental Delays
Empower EI: Comparing Early Intervention Approaches to Improve Communication in Toddlers With Developmental Delays
This study is testing three ways to deliver Early Intervention (EI) services for toddlers with developmental disabilities (DD). Children enrolled in EI speech therapy will receive one of three approaches: 1.
- Trial name
- NCT07227974
- Testing
- Therapist-Delivered Early Intervention Approach, Caregiver Coaching Early Intervention Approach, Parents Taking Action
- Where
- United States
- Volunteers
- 1,269 people
- Sponsor
- Northwestern University
Childhood Apraxia of Speech, Speech Sound Disorders
Feasibility and Preliminary Effects of a Therapeutic Approach Using Ultrasound Visual Biofeedback in Children With AFI: a Pilot Randomized Clinical Trial.
The aim of this study is to evaluate the feasibility of the Ultrax protocol and estimate preliminary effects on articulatory precision, prosody, and speech motor planning.
- Trial name
- PICOS (NCT07087249)
- Testing
- Ultrasound Visual Feedback, Waitlist
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Aline Mara de Oliveira
Cancer, Quality of Life
The PRISM Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults With Advanced Cancer
Multi-Site Randomized Controlled Trial testing the efficacy of the Promoting Resilience in Stress Management (PRISM) intervention among Adolescents and Young Adults with Advanced Cancer
- Conditions
- Cancer, Quality of Life, Anxiety, Depression
- Trial name
- PRISM-AC (NCT03668223)
- Testing
- Promoting Resilience in Stress Management (PRISM)
- Where
- 5 sites in United States
- Volunteers
- 269 people
- Sponsor
- Dana-Farber Cancer Institute
Traumatic Brain Injury, Neurogenic Communication Disorders
Narrative Discourse Treatment Development
Discourse impairments are breakdowns in meaningful communication beyond the level of single sentences and have a functional impact on the lives of Veterans with traumatic brain injury (TBI), disrupting return to work…
- Trial name
- NCT05008419
- Testing
- Narrative discourse treatment
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- VA Office of Research and Development
Speech Sound Disorder, Articulation Disorder
AI-Integrated Virtual Reality Speech Therapy in Children With Speech Sound Disorders
Speech sound disorders can affect intelligibility, learning, participation, and communication in children. This completed randomized controlled trial evaluated AI-Integrated Virtual Reality Speech Therapy (AI-IVR-ST) against…
- Conditions
- Speech Sound Disorder, Articulation Disorder, Phonological Disorder
- Trial name
- NCT07863778
- Testing
- AI-Integrated Virtual Reality Speech Therapy (AI-IVR-ST), Conventional Speech Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 64 people
- Sponsor
- Superior University
Autism Spectrum Disorder, Earthquake
The Effect of Parent Mediated Intervention Program on Children With ASD Exposed to Earthquake in Turkey in February 2023
After devastating natural events such as earthquakes, individuals with special needs experience much more difficulties. There is a limited number of studies investigating the impact of disasters on individuals with autism.
- Conditions
- Autism Spectrum Disorder, Earthquake, Behavior Problem of Childhood and Adolescence
- Trial name
- NCT05998382
- Testing
- Online group-based parent-mediated intervention program
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Sabri Hergüner
Stroke, Aphasia
Comparison of Therapeutic Effect Between Speech Rehabilitation Program and Speech Therapy in Stroke Patients With Aphasia
Our study will provide precise and intensive speech rehabilitation treatment program to patients with speech disorders after stroke, and compare clinical evaluations with the conventional speech therapy patient group.
- Conditions
- Stroke, Aphasia, Speech Therapy
- Trial name
- NCT06361901
- Testing
- Zenicog;language rehabilitation program, Conventional language rehabilitation
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Korea University Guro Hospital
Aphasia Following Cerebral Infarction, Stroke Ischemic
Brain Stimulation Effects on Post-Stroke Fatigue and Aphasia
The goal of this clinical trial is to determine if electrical brain stimulation applied to the front parts of the brain can help people who have had a stroke improve their fatigue, language, and attention.
- Conditions
- Aphasia Following Cerebral Infarction, Stroke Ischemic, Fatigue Symptom
- Trial name
- NCT07151677
- Testing
- tDCS (active), Attention-focused sentence comprehension treatment, Sentence comprehension treatment
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Syracuse University
Childhood-Onset Fluency Disorder (Stuttering)
Effects of Ecopipam or Placebo in Adults With Stuttering (Speak Freely)
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, Phase 2 exploratory study in adult subjects with childhood onset fluency disorder.
- Trial name
- NCT04492956
- Testing
- Ecopipam
- Where
- 9 sites in United States
- Volunteers
- 68 people
- Sponsor
- Emalex Biosciences Inc.
Autism Spectrum Disorder, Social Communication Disorder
Safety and Efficacy of NDTx-03 in Children and Adolescents With ASD or SCD
The purpose of this study is to evaluate the safety of NDTx-03 used together with treatment as usual (TAU) and to determine whether NDTx-03 plus TAU is more effective than TAU alone in improving social situation recognition and…
- Trial name
- NCT07770867
- Testing
- NDTx-03, TAU
- Where
- 7 sites in South Korea
- Volunteers
- 156 people
- Sponsor
- Neudive Inc.
Childhood Apraxia of Speech, Genetic Condition
Speech Therapy for Children With Rare Genetic Conditions and Childhood Apraxia of Speech
The goal of this trial is to learn if speech therapy can improve speech accuracy in children with rare genetic conditions and childhood apraxia of speech (CAS). This study will look at each child individually.
- Trial name
- NCT07815249
- Testing
- Rapid Syllable Transition Treatment, Dynamic Temporal and Tactile Cueing
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Murdoch Childrens Research Institute
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Pai.ACT - An Artificial Intelligence Driven Chatbot Assisted ACT
Limited psychological support for parents of children with special needs in Hong Kong can profoundly impact the child rehabilitation process and the well-being of parent-child dyads.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Neurodevelopmental Disorders, Intellectual Disability
- Trial name
- NCT06086951
- Testing
- Pai.ACT Group, Control Group
- Where
- 2 sites in Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Primary Progressive Aphasia(PPA), Progressive Aphasia
Remotely-supervised Neuromodulation in PPA
The goal of this clinical trial is to learn whether home-based brain stimulation combined with virtual speech-language therapy can improve communication abilities in adults with logopenic variant primary progressive aphasia…
- Conditions
- Primary Progressive Aphasia(PPA), Progressive Aphasia, Progressive Aphasia in Alzheimer's Disease, Logopenic Progressive Aphasia (LPA)
- Trial name
- NCT07260253
- Testing
- Lexical Retrieval Cascade Treatment, Remotely Supervised Transcranial Direct Current Stimulation- Active
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Maya Henry
Premature Infants
Using the Babble Boot Camp© Speech Therapy Approach With Babies Born Prematurely
Babble Boot Camp focuses on early speech and language development, environmental enrichment and supporting parent-infant interaction with the aim of improving communication outcomes and parental well-being in at risk children.
- Trial name
- BBCPrem (NCT07738224)
- Testing
- Babble Boot Camp
- Where
- 2 sites in Australia
- Volunteers
- 86 people
- Sponsor
- Murdoch Childrens Research Institute
Communication, Anxiety
AYA-PeerConnect: A Communication Coaching Intervention for Adolescent/Young Adult Cancer Survivors (AYACS)
This research is being done to test a communication coaching intervention pilot designed to improve communication quality between adolescent/young adult cancer survivors (AYACS) and their friends/peers.
- Conditions
- Communication, Anxiety, Depression, Social Isolation
- Trial name
- NCT07454460
- Testing
- Asynchronous coaching and artificial intelligence (AI) Yoodli coach sessions
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Milton S. Hershey Medical Center
Cleft Lip and Palate, Cleft Palate Children
Perceptions of High and Low Intensity Speech Intervention in Children With a Cleft Palate
A cleft (lip and) palate is the most common congenital abnormality of the face and skull with a significant social impact, affecting speech, hearing, feeding, oral behavior, dentition and satisfaction with appearance.
- Conditions
- Cleft Lip and Palate, Cleft Palate Children, Speech Therapy, Speech Disorders in Children
- Trial name
- NCT07781566
- Testing
- High-intensity speech therapy for children with cleft palate, Low-intensity speech therapy for children with cleft palate
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- University Ghent
Speech Therapy, Speech Disorders in Children
High-intensity vs Low-intensity Speech Intervention in Children With Phonological Speech Sound Disorders
Achieving speech that is understandable and acceptable to others is the key outcome in the treatment of phonological speech sound disorders. Therefore, speech therapy provided by a speech-language pathologist is essential.
- Conditions
- Speech Therapy, Speech Disorders in Children, Phonological (Speech) Disorder
- Trial name
- NCT07779759
- Testing
- High-intensity combined phonetic-phonological intervention, Low-intensity combined phonetic-phonological intervention
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Ghent
Autism Spectrum Disorder
Acceptability and Outcomes of an Online Parent-Mediated Intervention for Young Autistic Children
This preliminary single-arm pre-post interventional study was designed to evaluate the acceptability and preliminary clinical outcomes of an 8-week online group-based parent-mediated intervention (OYNA) for parents of young…
- Trial name
- NCT07763067
- Testing
- Online Group-Based Parent-Mediated Intervention (OYNA)
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Herguner Therapy Private Clinic
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Dance, Yoga, And Mindful Movement Training For ASD
The goal of this study is to learn if a dance, yoga, and mindful movement program can improve the lives of adults with autism spectrum disorder (ASD).
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism
- Trial name
- NCT07758088
- Testing
- Yoga, dance and Mindful Movement
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- USC Glorya Kaufman School of Dance