Clinical trials: Communications Disorders
Neurofibromatosis Type 1, Learning Disability
Interventions for Reading Disabilities in NF1
Neurofibromatosis Type 1 (NF1) is a common genetic disorder that is associated with a four times greater risk of learning disabilities, including reading disabilities, and a deficiency of neurofibromin - a protein important in a…
- Conditions
- Neurofibromatosis Type 1, Learning Disability, Reading Disability, NF1
- Trial name
- NCT02964884
- Testing
- Lovastatin, reading tutoring intervention
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Parkinson Disease
Intelligibility Assessment for Parkinson's Disease
The investigators aim at testing the efficacy of an app to measure sentence intelligibility in noise in speakers with Parkinson's disease and in healthy controls.
- Trial name
- NCT04829006
- Testing
- Understand Me For Life
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Long Island University
Other Developmental Disorders of Speech and Language
A Speech Sound and Phonemic Awareness Intervention in Flemish Early Childhood Education
The language intervention 'Kaatje Klank' is designed for stimulating the speech production and speech perception skills of 4-year-olds in an early childhood educational setting, in order to stimulate early literacy skills.
- Trial name
- NCT02313025
- Testing
- speech sound intervention, World-project
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Mentoring
Effects of a Peer-mentoring Program on Undergraduate Students' Outcomes and Perspectives Related to a Career in Communication Sciences and Disorders
The purpose of the study is to investigate the effects of implementing a semester-long mentoring program in Communication Sciences \& Disorders on its participants and how the experience differs from the students who did not…
- Trial name
- NCT07308821
- Testing
- mentor program
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Montclair State University
Developmental Language Disorder, Speech Sound Disorder
A Framework For Linking Sequential Pattern Rules in DLD: Perception in Adults
This broad aim of this clinical study is to assess the hypothesis that morphological and phonological deficits are linked by a broader deficit in sequential pattern learning.
- Conditions
- Developmental Language Disorder, Speech Sound Disorder, Specific Language Impairment
- Trial name
- NCT04996472
- Testing
- Sensitivity to phonological rules: Adults, Sensitivity to semantic category cues: Adults
- Where
- 2 sites in United States
- Volunteers
- 933 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Pregnancy Related, Obesity
Evidence-based Educational Materials and Local Resources for Improving Exercise-related Outcomes During Pregnancy
Despite the well-established benefits of physical activity, only 23% of pregnant women report exercising in accordance with guidelines recommended by the American Congress of Obstetricians and Gynecologists.
- Trial name
- NCT03504267
- Testing
- Physical Activity Education and Resources
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Western Kentucky University
Parkinson Disease, REM Sleep Behavior Disorder
Detecting Parkinson's Disease Through Speech Analysis
Speech is an important indicator of motor function and movement coordination and can be extremely sensitive to involvement in the course of neurologic diseases.
- Trial name
- NCT03133611
- Testing
- Speech assessment, Routine clinical assessment
- Where
- 7 sites in United States, Austria and 5 more
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Dyslexia, Developmental
Neural Mechanisms of Successful Intervention in Children With Dyslexia
Dyslexia, an impairment in accurate or fluent word recognition, is the most common learning disability affecting roughly ten percent of children.
- Trial name
- NCT04323488
- Testing
- Lindamood-Bell Seeing Stars
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Stanford University
Developmental Dyslexia
Prediction and Intervention in Developmental Dyslexia
The long-term goal of this study is to improve prediction of poor reading outcome at preschool age by using a combination of behavioural and neuroimaging measures and to evaluate a specific computerized training program to…
- Trial name
- LEXI (NCT02217696)
- Testing
- Computerized reading training
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Reading Disability, Dyslexia
Eye Movements and Reading Disabilities
The mechanism of the eye movement anomalies seen in dyslexic patients is not well defined. Some optometrists use observational eye movement tests as screening devices for dyslexia and advocate eye movement therapy as a treatment…
- Trial name
- EOMRD (NCT01860027)
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Scripps Health
Autism Spectrum Disorder, Attention Deficit Disorder With Hyperactivity (ADHD)
Pai.ACT: AI-Driven ACT Chatbot for Mental Health Triage and Service Evaluation
Parents of children with special needs in Hong Kong often face limited psychological support, which can negatively impact the child rehabilitation process and the well-being of parent-child relationships.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Disorder With Hyperactivity (ADHD), Neurodevelopmental Disorder (Diagnosis), Dyslexia
- Trial name
- NCT06808555
- Testing
- Pai.ACT Group, Control Group
- Where
- 20 sites in Hong Kong
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Primary Progressive Aphasia, Semantic Dementia
Treatment for Speech and Language in Primary Progressive Aphasia
Primary progressive aphasia (PPA) is a progressive neurological disorder that causes a gradual decline in communication ability as a result of selective neurodegeneration of speech and language networks in the brain.
- Conditions
- Primary Progressive Aphasia, Semantic Dementia, Semantic Memory Disorder, Logopenic Progressive Aphasia
- Trial name
- NCT04881617
- Testing
- Lexical Retrieval Training (LRT), Video-Implemented Script Training for Aphasia (VISTA)
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Colonic Neoplasms, Colorectal Neoplasms
Evaluating Strategies to Present Colon Cancer Screening Information
This is a study examining the effects of different educational-motivational materials about colorectal cancer screening on perceptions and intentions to get screened.
- Conditions
- Colonic Neoplasms, Colorectal Neoplasms, Colonic Diseases, Gastrointestinal Neoplasms
- Trial name
- NCT02485561
- Testing
- Health communication intervention, Education information
- Where
- United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Developmental Language Disorder
Neuroimaging Reveals Treatment-related Changes in DLD
Children with developmental language disorders (DLD, aka specific language impairment), a prevalent pediatric disorder, experience hallmark grammar deficits with life-long impacts on educational and occupational outcomes.
- Trial name
- NCT05268341
- Testing
- My Sentence Builder
- Where
- 6 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
ASF Consumption
Transforming Food System Evaluation in Mozambique
Global Alliance for Improved Nutrition (GAIN)'s "Transforming Food Systems to Improve Diet Quality and Resilience for the Most Vulnerable" program seeks to improve consumption of healthy foods by improving supply, increasing…
- Trial name
- NCT05858151
- Testing
- Food system and demand generation
- Where
- Mozambique
- Volunteers
- 5,216 people, healthy volunteers welcome
- Sponsor
- RTI International
Voice, Speech
Virtual Reality as a Tool for Training Public Speaking Skills in Higher Education Students
According to the scientific literature, public speaking (PS) is an important skill for students to master. However, a large proportion of students do not feel comfortable speaking in public.
- Conditions
- Voice, Speech, Virtual Reality Simulation, Healthy Adult
- Trial name
- NCT07392554
- Testing
- Indirect Method, Direct Method
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Liege
Myopia, Small-incision Lenticule Extraction (SMILE) Surgery
Potential Risk Factors and Predictive Model Construction of OBL During SMILE
To explore the prediction of OBL by deep learning model in SMILE surgery
- Trial name
- NCT06577012
- Testing
- Small incision lenticule extraction
- Where
- China
- Volunteers
- 4,678 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Stroke, Stroke (CVA) or TIA
The Imperial Comprehensive Cognitive Assessment in Cerebrovascular Disease (IC3)
Stroke is a major cause of death and disability worldwide, frequently resulting in persistent cognitive deficits among survivors.
- Conditions
- Stroke, Stroke (CVA) or TIA, Dementia, Vascular, Cerebrovascular Disorders
- Trial name
- IC3 (NCT05885295)
- Testing
- MRI brain, Blood tests, cognitive assessments
- Where
- United Kingdom
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Primary Progressive Aphasia
Speech-Language Treatment With Remotely Supervised Transcranial Direct Current Stimulation in Primary Progressive Aphasia
Primary progressive aphasia (PPA) is a disorder characterized by gradual decline in speech-language ability caused by underlying neurodegenerative disease.
- Trial name
- NCT05901233
- Testing
- Remotely supervised Transcranial Direct Current Stimulation (RS-tDCS), Lexical Retrieval Training (LRT), Video Implemented Script Training in Aphasia (VISTA)
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Prediabetes
Training Induced Muscle-Adipose EV Communication
This study examines how muscle cells communicate with fat cells through tiny packages called extracellular vesicles (EV) during exercise.
- Trial name
- TIMER2 (NCT07106450)
- Testing
- Acute Resistance Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yuan Wen